Charles N. Hunter, one of North Carolina's outstanding black reformers, was born a slave in Raleigh around 1851, and he lived there until his death in 1931. As public school teacher, journalist, and historian, Hunter devoted his long life to improving opportunities for blacks. A political activist, but never a radical, he skillfully used his journalistic abilities and his personal contacts with whites to publicize the problems and progress of his race. He urged blacks to ally themselves with the best of the white leaders, and he constantly reminded whites that their treatment of his race ran counter to their professed religious beliefs and the basic tenets of the American liberal tradition. By carefully balancing his efforts, Hunter helped to establish a spirit of passive protest against racial injustice. John Haley's compelling book, largely based on Hunter's voluminous papers, affords a unique opportunity to view race relations in North Carolina through the eyes of a black man. It also provides the first continuous survey of the black experience in the state from the end of the Civil War to the Great Depression, an account that critiques the belief that race relations were better in North Carolina than in other southern states.
Recent developments in DNA marker technologies, in particular the emergence of Single Nucleotide Polymorphism (SNP) discovery, have rendered some of the traditional methods of genetic research outdated. Next Generation Sequencing and Whole Genome Selection in Aquaculture comprehensively covers the current state of research in whole genome selection and applies these discoveries to the aquaculture industry specifically. The text begins with a thorough review of SNP and transitions into topics such as next generation sequencing, EST data mining, SNP quality assessment, and whole genome selection principles. Ending with a discussion of the technology's specific applications to the industry, this text will be a valuable reference for those involved in all aspects of aquaculture research. Special Features: Unique linking of SNP technologies, next generation sequencing technologies, and whole genome selection in the context of aquaculture research Thorough review of Single Nucleotide Polymorphism and existing research 8-page color plate section featuring detailed illustrations
U.S. Ranger Major John Lock vividly brings to life the horrific battles and the heroic exploits--from the French and Indian War to Desert Storm--of a special breed of men for whom valor, honor, and country mean more than life itself. Photo insert.
From acclaimed historian John Wukovits, the untold story of the USS Laffey and her crew, who heroically withstood twenty-two kamikaze attacks at Okinawa which the US Navy describes Òas one of the great sea epics of the warÓ
Parkinson's disease is a neurological disorder with cardinal motor signs of resting tremor, bradykinesia and lead-pipe rigidity. In addition, many patients display non-motor symptoms, including a diminished sensation of smell, gastrointestinal problems, various disorders of sleep and some cognitive impairment. These clinical features - particularly the motor signs - manifest after a progressive death of many dopaminergic neurones in the brain. Although currently available, conventional therapies can reduce the signs of the disease, the progression of this neuronal death has proved difficult to slow or stop, and the condition is relentlessly progressive. Hence, there is a real need to develop a treatment that is neuroprotective, one that slows the pathology of the disease effectively. At present, there are several neuroprotective therapies in the experimental pipeline, but these are for the patients of tomorrow. This book focuses on two therapies that are readily available for the patients of today. They involve the use of exercise and light (i.e. photobiomodulation, the use of red to infrared light therapy (λ=600-1070nm) on body tissues). The two therapies are tied together in several ways. First, in animal models of Parkinson's disease, they each have been shown to offer the key feature of neuroprotection, stimulating a series of built-in protective mechanisms within the neurones, that helps their survival, to self-protect and/or self-repair. There are also some promising indications of neuroprotection and many beneficial outcomes in parkinsonian patients. Further, both exercise and light therapies are similar in that they are non-invasive and safe to use, with no known adverse side-effects, making their combination with the conventional therapies, such as dopamine replacement drug therapy and deep brain stimulation, all the more feasible. Given the heterogeneity of Parkinson's disease in humans, tackling the condition from a range of different angles - with a number of different therapies - would only serve to enhance the positive outcomes. This book considers the use of exercise and light therapies, proposing that they have the potential to make a powerful "dynamic duo", offering a most effective neuroprotective treatment option to patients.
In addition to listings for more than 30,000 American records of the 1950s-1980s, this edition also provides current collector pricing for every record listing, giving collectors more information for their dollar.
This book describes the way in which the human brain is supplied with blood and how the brain uses this to provide nutrients, primarily oxygen and glucose, to brain cells in order to maintain healthy brain function. In particular, it focuses on the quantitative nature of blood flow and metabolism. The book covers models of blood flow and metabolism and how these can be measured using a variety of imaging and non-imaging techniques. It also examines how cerebral blood flow is controlled in response to a wide variety of challenges and how it changes with normal physiological variation and in response to a large number of pathological conditions, including stroke and dementia.As the first substantial book for over ten years in a fast-changing field, it highlights how the subject has progressed in the last couple of decades. It tackles the subject in a quantitative way, underlining its importance in both technical and clinical fields. Audiences with a technical or clinical background, especially researchers and postgraduate students in biomedical engineering or medicine, will find this a valuable read.
The South Carolina 2nd Regiment Rifles was organized during the spring of 1862 using the 5th South Carolina Battalion Rifles as its nucleus. It was organized from extra companies initially intended for Orr's Rifles. These companies were organized into a battalion that was officially designated the Fifth South Carolina Infantry Battalion. The unit served in South Carolina, then was ordered to Virginia and assigned to General Jenkins' and Bratton's Brigade. It participated in the Seven Days' Battles and the conflicts at Second Manassas, Sharpsburg, and Fredericksburg. Later the regiment was with Longstreet at Suffolk and D.H. Hill in North Carolina. It moved again with Longstreet but did not take part in the Battle of Chickamauga. The unit was involved in the Knoxville operations, returned to Virginia, and saw action at The Wilderness, Spotsylvania, and Cold Harbor. After enduring the hardships of the Petersburg siege south and north of the James River, it ended the war at Appomattox.
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