Managing Integrated Healthcare Systems: A Guide for Health Executives provides those managers engaged in and studying healthcare the understanding and the knowledge required to succeed in this dynamic industry.
Managing Integrated Healthcare Systems: A Guide for Health Executives provides those managers engaged in and studying healthcare the understanding and the knowledge required to succeed in this dynamic industry.
Actins are a highly conserved family of proteins found in virtually all eukaryotic cells. They have prolific roles in cell motility - from the contraction of striated muscle to the movement of organelles within cells, and are known to interact with a diverse number of proteins families from myosins to gelsolins. This up-to-date edition gives a comprehensive account of actin sequence, mutation and structure as well as providing insight into ligand-binding sites and drug and toxin binding. Illustrated throughout, this modern text also contains an extensive bibliography for the interested reader.
This critical, state-of-the-art review brings together the scattered and often controversial information on multidrug resistance reversal. Leading scientists in the field cover P-glycoprotein, the genetics of resistance, and its reversal by drugs. Resistance modifiers and modulators are tabulated and critically evaluated. Reversal of Multidrug Resistance in Cancer is important reading for oncologists, cancer chemotherapists, and other cancer researchers.
On the Other Shore explores the social history of Italian communities in South America and the transnational networks in which they were situated during and after World War I. From 1915 to 1921 Italy's conflict against Austria-Hungary and its aftermath shook Italian immigrants and their children in the metropolitan areas of Buenos Aires, Montevideo, and São Paulo. The war led portions of these communities to mobilize resources--patriotic support, young men who could enlist in the Italian army, goods like wool from Argentina and limes from Brazil, and lots of money--to support Italy in the face of "total war." Yet other portions of these communities simultaneously organized a strident movement against the war, inspired especially by anarchism and revolutionary socialism. Both of these factions sought to extend their influence and ambitions into the immediate postwar period. On the Other Shore demonstrates patterns of social cohesion and division within the Italian communities of South America; reconstructs varying transatlantic and inter-American networks of interaction, exchange, and mobility in an "Italian Atlantic"; interrogates how authorities in Italy viewed their South American "colonies"; and uncovers ways that Italians in Latin America balanced and blended relationships and loyalties to their countries of residence and origin. On the Other Shore's position at the intersection of Latin American history, Atlantic history, and the histories of World War I and Italian immigration thereby engages with and informs each of these subject areas in distinctive ways.
Vasopressin is a hormone which has an increasingly important profile. Not only does it play a physiologically significant role in renal water regulation but it also has other renal actions and plays a role in overall cardiovascular control. Even more interesting is the recent growing interest in its potential effects on the brain, notably its influence on specific behaviours.This monograph about the polypeptide vasopressin covers all aspects relating to the production, control of release, and actions of this molecule within the body, including its roles as a hormone and as a central neurotransmitter. A consideration of the evolution of the molecule across the species and a brief historical perspective are also included. Clinical conditions associated with hypo- and hyper-production states are considered together with aspects of treatment, in addition to other clinical correlates./a
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