This book is filled with practical advice for inventors and managers. It charts the course from ideas and needs through selecting the best projects and turning them into successes. Also, the exclusive Inventor Profile is a powerful tool for identifying people with the most inventive potential. It comes from the most productive inventors in the U.S.. There are 45 figures and tables, all backed up with new methods of research and analysis. Yet the style is direct and highly readable.
This book provides the first comprehensive economic valuation of U.S. National Parks (including monuments, seashores, lakeshores, recreation areas, and historic sites) and National Park Service (NPS) programs. The book develops a comprehensive framework to calculate the economic value of protected areas, with particular application to the U.S. National Park Service. The framework covers many benefits provided by NPS units and programs, including on-site visitation, carbon sequestration, and intellectual property such as in education curricula and filming of movies/ TV shows, with case studies of each included. Examples are drawn from studies in Santa Monica Mountains National Recreation Area, Golden Gate National Recreation Area, Everglades National Park, and Chesapeake Bay. The editors conclude with a chapter on innovative approaches for sustainable funding of the NPS in its second century. The framework serves as a blueprint of methodologies for conservationists, government agencies, land trusts, economists, and others to value public lands, historical sites, and related programs, such as education. The methodologies are relevant to local and state parks, wildlife refuges, and protected areas in developed and developing countries as well as to national parks around the world. Containing a series of unique case studies, this book will be of great interest to professionals and students in environmental economics, land management, and nature conservation, as well as the more general reader interested in National Parks.
Given the frequent movement of commercial plants outside their native location, the consistent and standard use of plant names for proper identification and communication has become increasingly important. This second edition of World Economic Plants: A Standard Reference is a key tool in the maintenance of standards for the basic science underlyin
Why did Ptolemy's theory cause problems for the church? What is the big secret concerning the "?Age" of the earth? Why do many scientists reject the use of design in explaining origins? The seemingly absurd idea that all matter, energy, space, and time once exploded from a point of extreme density has captured the imagination of scientists and laypersons for decades. The big bang has provided a central teaching for the eons of time of "cosmic evolution", undermining the history and cosmology of the Bible. It is a theory that fails, even violating the very physical laws on which it is purportedly based. In this easy-to-read format, authors Alex Williams and John Hartnett explode this naturalistic explanation for the universe, and show that the biblical model provides a far better explanation of our origins. This fully indexed, illustrated analysis of the big bang theory is an invaluable help in understanding and countering a world view that is as chaotic and destructive as its name implies.
Dr. Perloff, the founding father of the field of adult congenital heart disease, presents a decade's worth of research and clinical data in the completely redefined 3rd edition to bring you the most current information. With advances in diagnosis and treatment in children, more and more of those with CHD survive well into adulthood. Expert contributors in various fields offer a multi-disciplinary, multi-system approach to treatment so you get comprehensive coverage on all aspects of the subspecialty, including basic unoperated malformations, medical and surgical perspectives, postoperative residue, and sequelae. As someone who treats these patients, you need to be ready to provide the continual care they require. - Conveys a multidisciplinary, multi-system approach to the lifelong care of adult CHD patients to put treatment in a broader context. - Presents information in a consistent, logical style so the information you need is easy to find and apply. - Supplements the text with 600 clear conceptual illustrations to clarify difficult concepts. - Features completely rewritten chapters to include the latest developments in the field—such as major advances in surgical and interventional techniques—and the various needs of patients with adult CHD. - Incorporates recently published trials such as those involving cyanotic CHD and atherogenesis, coronary microcirculation, and pathogenesis of thrombocytopenia to supplement the chapter on cyanotic CHD. - Emphasizes advances in imaging in a new section—edited by an expert—that covers echocardiography as well as specialized imaging techniques. - Illustrates the full range of advances in the field with 600 images that reflect the latest progress. - Includes new chapters—Global Scope of ACHD; Cardiac Transplantation; Electrophysiologic Abnormalities in Unoperated Patients and Residue and Sequelae After Cardiac Surgery—to provide you with the latest information on the growth of the subspecialty and its effect on treatment. - Presents revisions by a new authorship of experts in infectious disease, genetics and epidemiology, sports medicine, neurology, cardiac surgery, cardiac anesthesiology, and more.
The first up-to-date source on the subject in more than a decade, this authoritative and all-encompassing guide summarizes the latest findings on the epidemiology, pathogenesis, pathophysiology, clinical manifestations, diagnosis, and treatment of infective endocarditis. Written by a world recognized expert with more than 35 years of experience in
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
Amyloids, Prions and Beta Proteins is the last volume of the three-part thematic series on Fibrous Proteins in the Advances in Protein Chemistry serial. Fibrous proteins act as molecular scaffolds in cells providing the supporting structures of our skeletons, bones, tendons, cartilage, and skin. They define the mechanical properties of our internal hollow organs such as the intestines, heart, and blood vessels. This volume covers such topics as Beta-Structures in Fibrous Proteins; B-Silks: Enhancing and Controlling Aggregation; Beta-Rolls, Beta-Helices and Other Beta-Solenoid Proteins; Natural Triple B-Stranded Fibrous Folds; Structure, Function and Amyloidogenesis of Fungal Prions: Filament Polymorphism and Prion Variants; X-Ray Fiber and powder Diffraction of PRP Prion Peptides; From the Polymorphism of Amyloid Fibrils to Their Assembly Mechanism and Cytotoxicity; Structural Models of Amyloid-like Fibrils.
A comprehensive and sympathetic history of all branches of the Mennonites and Amish, including a portrayal of their doctrine, life, and piety. It attempts to present a true picture of the Christian bodies in Indiana and Michigan which are descended from the European Anabaptists of the sixteenth century.
This book develops the theoretical and experimental basis of quantum optics, i.e. the interaction of individual particles of light (photons) with matter, starting from elementary quantum theory. The self-contained exposition will be useful to graduate students in physics, engineering, chemistry, and senior undergraduates in physics.
This timely volume provides a comprehensive account of the natural history of the organisms associated with the deep-sea floor and examines their relationship with this inhospitable environment--perhaps the most remote and least accessible location on the planet. The authors begin by describing the physical and chemical nature of the deep-sea floor and the methods used to collect and study its fauna. Then they discuss the ecology of the deep sea by exploring spatial patterns, diversity, biomass, vertical zonation, and large-scale distribution of organisms. Subsequent chapters review current knowledge of feeding, respiration, reproduction, and growth processes in these communities. The unique fauna of hypothermal vents and seeps are considered separately. Finally, there is a pertinent discussion of human exploitation of deep-sea resources and potential use of this environment for waste disposal.
The study of valvular heart disease has progressed rapidly over the past two decades. The understanding of etiology and natural history, the precision of noninvasive assessment, and the surgical and interventional management of valve disease have all improved dramatically. Coupled with an appreciation of physiologic principles, thoughtful interviews and physical exam, current technology allows clinicians to characterize all types of valve lesion. In addition, evolving techniques in interventional cardiology and cardiac surgery, guided by quantitative outcome analysis, have reduced the morbidity and mortality of these procedures. Reflecting all the above and evidence-based medical practice, the authors aim to provide a concise and straightforward guide to the recognition and management of valvular heart disease, complemented by current guidelines and abundant high-quality images. It will be a valuable reference for all involved in the care of patients with valvular heart disease, including cardiologists in practice and training, young hospital doctors, general physicians, cardiac nurse specialists, and medical students.
lt is a tremendous achievement to have provided this highly comprehensive but readable text, which informs such a large group of researchers and clinicians." Christopher Kennard, PhD, FRCP, FMedSci, Professor of Clinical Neurology, Head, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom. "A monograph written with deep knowledge, understanding, wisdom, clarity, intelligibility - the superlatives could go on and on... A remarkable achievement and a great gift to all of us from the two modern giants of eye movement disorders." Michael Halmagyi, MD, Eye and Ear Research Unit, Neurology Department, Royal Prince Alfred Hospital, The University of Sydney, Australia. "The fifth edition of The Neurology of Eye Movements is a must for all neurologists and neuroscientists interested in how the human vestibular and oculomotor systems adapt to movement in space and to optimally viewing the world and its contents." Louis R. Caplan, MD, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
The past few years have seen considerable advances in our understanding of the molecular basis underlying cutaneous cell adhesion mechanisms. Co-authored by a number of leading experts in the field ^Cell Adhesion and Migration in Skin Disease provides a comprehensive overview of the critical role played by cell adhesion in determining the structure and function of both healthy and diseased human skin. The book is divided into three main sections, with each one addressing a principal function of adhesion molecules. The first part focuses on the epidermis, which as the skin's outermost layer, acts as the human body's primary barrier of defence. Roles played by cytoskeletal intermediate filaments and junctional complexes in cutaneous cell adhesion are emphasised with descriptions of blistering skin diseases that can arise if these molecules malfunction. The second part describes the macromolecular interactions responsible for the anchorage of cells to the underlying extracellular basement membrane. The experimental approaches detailed in the text not only reveal how the molecular components of the dermal-epidermal junction have been elucidated, but also highlight how mutations in the genes which encode these molecules are responsible for many heritable skin diseases. Leukocytes continually infiltrate the skin and patrol it for potentially harmful pathogens. Control of leukocyte adhesion to resident cells within the skin and to the extracellular matrix plays a key role in controlling these processes. These mechanisms constitute the primary focus of the final section. The pivotal role of leukocytes is examined in conjunction with the chronic inflammatory diseases which arise when components of the skin's finely tuned defence strategy go awry and the potential for these anomalies to be pinpointed as important immunotherapeutic targets for skin diseases.
The direct-to-consumer business model has transformed how people seek out goods and services from music to mortgages. So what happens now that the revolution has come for healthcare? While consumers have begun to insist on healthcare that is as convenient and personalized as nearly every other good or service they purchase, most healthcare provider organizations, physicians, and insurance companies remain woefully unprepared to meet this demand. Choice Matters is the healthcare sector's guide to understanding and delivering the brand of consumer-centered care that is an imperative for the Zocdoc age. Drawing on the authors' diverse backgrounds in medicine, business, and public policy, this practically-oriented resource offers an on-the-ground introduction for clinicians and managers to better understand: Â- The differences between healthcare and other consumer-driven markets Â- What factors are most important for consumers in seeking care providers Â- How consumers make decisions about healthcare Â- The system-wide effects of increased consumer choice in healthcare Â- The important distinction between patients and consumers By celebrating the possibilities inherent to consumer-centered healthcare, Choice Matters offers a refreshing, empirically informed take on how healthcare in the United States can flourish, not wither, in the new economy.
The leading scholarly and theoretical approach to clinical reasoning in occupational therapy, Schell & Schell’s Clinical and Professional Reasoning in Occupational Therapy, 3rd Edition, continues a successful tradition of not only teaching occupational therapy students how practitioners think in practice, but detailing the why and how to develop effective reasoning in all phases of their careers. More practical and approachable than ever, this updated 3rd Edition incorporates a new emphasis on application and reflects the personal insights of an international team of contributors, giving emerging occupational therapists a professional advantage as they transition to professional practice.
Proceedings from a 2016 sustainability symposium Information from REWAS 2016 proceedings were collected and published in REWAS 2016: Towards Materials Resource Sustainability. This collection covers the proceedings of the symposium sponsored by the Recycling and Environmental Technologies Committee; the Materials and Society Committee; the Extracting & Processing Division; and the Light Metals Division of the Minerals, Metals and Materials Society. Topics covered include: enabling and understanding the sustainability related to ferrous and non-ferrous metals processing; batteries; rare earth element applications; and building materials. At REWAS 2016, materials professionals exchanged ideas with other researchers and stakeholders to outline a path toward a resource-efficient society.
Using a broad selection of classic and current sources, The Natural History of the Earth probes selected discussions within biology, climatology, geology, and geomorphology and explores a selection of debates about Earth and life history, considering their origins and their present state-of-play. After outlining the arguments, placing them in an historical context and indicating their significance, the book goes on to deal with specific debates. In the geosphere section, topics covered include geological processes, the bombardment hypothesis, frigid climates and cataclysmic floods, and in the section concerning the biosphere, the topics covered include evolutionary patterns, mass extinctions, patterns in life’s history and life–environment connections. Written in a clear and accessible style, this volume will interest Earth and life scientists, physical geographers and any informed person fascinated by long-term Earth history. This accessible volume is illustrated throughout with over fifty informative diagrams, photographs, tables and over 700 references.
This textbook presents techniques for statistical analysis in the absence of strong assumptions about the distributions generating the data. Rank-based and resampling techniques are heavily represented, but robust techniques are considered as well. These techniques include one-sample testing and estimation, multi-sample testing and estimation, and regression. Attention is payed to the intellectual development of the field, with a thorough review of bibliographical references. Computational tools, in R and SAS, are developed and illustrated via examples. Exercises designed to reinforce examples are included. Important techniques covered include Rank-based techniques, including sign, Kruskal-Wallis, Friedman, Mann-Whitney and Wilcoxon tests, are presented. Tests are inverted to produce estimates and confidence intervals. Multivariate tests are explored. Techniques reflecting the dependence of a response variable on explanatory variables are presented. Density estimation is explored. The bootstrap and jackknife are discussed. This text is intended for a graduate student in applied statistics. The course is best taken after an introductory course in statistical methodology, a course in elementary probability, and a course in regression. Mathematical prerequisites include calculus through multivariate differentiation and integration, and, ideally, a course in matrix algebra.
Over the past few decades, the book series Linguistische Arbeiten [Linguistic Studies], comprising over 500 volumes, has made a significant contribution to the development of linguistic theory both in Germany and internationally. The series will continue to deliver new impulses for research and maintain the central insight of linguistics that progress can only be made in acquiring new knowledge about human languages both synchronically and diachronically by closely combining empirical and theoretical analyses. To this end, we invite submission of high-quality linguistic studies from all the central areas of general linguistics and the linguistics of individual languages which address topical questions, discuss new data and advance the development of linguistic theory.
The 1924 Filipino sugar strike came as a shocking blow to Hawaii's self-image. The tragic deaths at Hanapepe were regarded as an anomaly in Hawaii's peaceful, idyllic image. Yet as Reinecke's research clearly indicates, the sugar industry was building to a climax in the 1920s. In the traditional sense, the strike was a "piecemeal" affair, lacking clear goals and having virtually no leadership or plans. These young, largely illiterate, Filipinos wrought massive changes into a more modern, industrial mode; into what was widely known thereafter as the Big Five. Evidence from the University of Hawaii's new archive collection, the H.S.P.A. Plantation Archives, not available to Dr. Reinecke completes the picture of the strike with evidence of the massive changes in management, recruitment and labor policies. The strike remains as he described it in his title: "The Piecemeal Strike." The new evidence rounds out the transformation of the industry.
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