John C Lucchesi's Books

Chromatin And Gene Function: A Primer

By: John C Lucchesi

Write a review Read reviews Take a Quiz Solve Book Puzzle

Chromatin And Gene Function: A Primer

By: John C Lucchesi

The purpose of this primer is to provide students, teachers as well as academic and industry researchers with a succinct account of the chemical and structural features of chromatin and the role that these features play in the maintenance and function of the genetic material.It is universally accepted that DNA is the carrier of the genetic information that is transmitted from parents to their offspring and that it is responsible for the anatomy, physiology and behavior of all individuals throughout development and adult life. Yet, how this information is retrieved and used selectively to allow a fertilized egg to become an organism made up of myriads of different cells and tissues is not as evident and easily understood.Dr Lucchesi, an internationally known researcher and teacher, provides an easily opened window into the role that the complex of proteins and nucleic acids that are associated with the DNA play in mediating gene expression and in responding to environmental circumstances.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

163

Publisher

World Scientific

Published Date

ISBN 10

9811258457

ISBN 13

9789811258459

Epigenetics, Nuclear Organization & Gene Function

With implications of epigenetic regulation and genetic architecture for human development and health

By: John C. Lucchesi

Write a review Read reviews Take a Quiz Solve Book Puzzle

Epigenetics, Nuclear Organization & Gene Function

With implications of epigenetic regulation and genetic architecture for human development and health

By: John C. Lucchesi

Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine. This book's primary goal is to establish a framework that can be used to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. A further aim is to highlight the role played by the three-dimensional organization of the genetic material itself (the complex of DNA, histones and non-histone proteins referred to as chromatin), and its distribution within a functionally compartmentalized nucleus. This architectural organization of the genome plays a major role in the subsequent retrieval, interpretation, and execution of both genetic and epigenetic information.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

240

Publisher

Oxford University Press

Published Date

ISBN 10

0192567160

ISBN 13

9780192567161

Environmental Issues in the Mediterranean

Processes and Perspectives from the Past and Present

By: John B. Thornes,John Wainwright

Write a review Read reviews Take a Quiz Solve Book Puzzle

Environmental Issues in the Mediterranean

Processes and Perspectives from the Past and Present

By: John B. Thornes,John Wainwright

The Mediterranean has been subject to changing human settlement and land use patterns for millennia. This book reviews both physical and social aspects of this region, in relation to its environment.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

510

Publisher

Routledge

Published Date

ISBN 10

1134729863

ISBN 13

9781134729869

Book's by John C Lucchesi

Chromatin And Gene Function: A Primer

Chromatin And Gene Function: A Primer

Epigenetics, Nuclear Organization & Gene Function

Epigenetics, Nuclear Organization & Gene Function

Environmental Issues in the Mediterranean

Environmental Issues in the Mediterranean

Username

Password

Username

Password

Password again

Birthday

Email