Joel Pardee's Books

Cell Origin, Structure, and Function

How Cells Make a Living : a Visual Approach

By: Joel D. Pardee

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Cell Origin, Structure, and Function

How Cells Make a Living : a Visual Approach

By: Joel D. Pardee

In this lecture, we will briefly review the principles of physics, central metabolism, and cell biology that make health possible. This exercise is appropriate for those of us who have set before ourselves the problem of understanding and preserving life processes, because it is through the medium of a cell that energy creates life. We are aware that life processes require a complex set of biochemical reactions. But that is not enough. Not only are complex reactions necessary, but superimposed on this essential requirement is the necessity to build and maintain a dynamic cellular structure. Chemical energy builds cells. In this lecture, we will see how cells extract energy from the entropic dissolution of the universe, how the extracted energy is used to build cell structure, and how cell structure determines cell function. Table of Contents: Origin and Energy of Life / How Cells Make a Living / Order From Chaos: Entropy and The River of Time / Capturing Entropy / Cell Architecture / Why Cells are Compartmentalized. The Function of Organelles / Cell Function / The Secretory Pathway / The Golgi Apparatus / Mitochondria / The Cytoskeleton: How Organelles are Organized / Vesicle Transport / Mitosis / Energy and Metabolism / References

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Morgan & Claypool Publishers

Published Date

ISBN 10

1615042679

ISBN 13

9781615042678

Understanding Breast Cancer

Cell Biology and Therapy -- A Visual Approach

By: Joel D. Pardee

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Understanding Breast Cancer

Cell Biology and Therapy -- A Visual Approach

By: Joel D. Pardee

The mysterious disease of cancer, including breast cancer, has plagued mankind since the dawn of recorded history. Regarding the elusive cause of the disease, the "Father of Medicine," Hippocrates of Athens (460–377 BC), wrote that, "For instability is characteristic of the humours and so they may be easily altered by nature and by chance." The enigma has persisted until today. In 1971, then President Richard Nixon signed the National Cancer Act and declared a "War on Cancer." He believed the counsel of scientists and physicians that if sufficient resources were committed to the fight, cancer could be virtually eliminated within 5 years. The prophesy failed. Although mortality from a few cancers, most notably leukemias, has been significantly reduced, carcinomas, cancers of the epithelium, which account for 80% of cancer deaths, remain unchanged. While tremendous advances have taken place in our understanding of the molecular and cellular mechanisms operant in cancer, it has proven exceedingly difficult to prevent the occurrence or to halt the progress of the disease. The very best therapy remains early detection while the primary tumor is small and localized to a single site, followed by removal of the offending growth by surgery and/or radiation. The great challenge of finding a cure confronts us yet, and it is effective intervention at the molecular level that offers our best hope. We still must find the "magic bullet.

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Biota Publishing

Published Date

ISBN 10

1615040765

ISBN 13

9781615040766

America

Volume I

By: Joel Cook

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America

Volume I

By: Joel Cook

Reproduction of the original: America by Joel Cook

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Page Count

150

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BoD – Books on Demand

Published Date

ISBN 10

3734038812

ISBN 13

9783734038815

Wild Ride

The History and Lore of Rodeo

By: Joel H. Bernstein

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Wild Ride

The History and Lore of Rodeo

By: Joel H. Bernstein

Rodeos" presents a fascinating history of this Western American institution,rom its rugged beginnings on the ranch to today's very lucrativerofessional circuits. This book captures the mystique of the cowboy and hislace in Western folklore, from the early days when groups of cowboys fromeighboring ranches met to settle arguments over who was the best aterforming ranching tasks to the multi-million dollar prizes and endorsementswarded to professionals today. Experience first-hand the energy, electricity,nd exhilaration of the rodeo through stunning colour photography andintage illustrations that tell the stories of these courageous and athleticodeo characters, and highlights of important moments throughout rodeoistory.

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188

Publisher

Gibbs Smith

Published Date

ISBN 10

1586857452

ISBN 13

9781586857455

The Actin Cytoskeleton in Cell Motility, Cancer, and Infection

By: Joel Pardee

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The Actin Cytoskeleton in Cell Motility, Cancer, and Infection

By: Joel Pardee

The cell is no longer considered to be a bag full of enzymes dissolved in a liquid cytoplasm. It is now known that the cytoplasm is an exquisitely ordered structure of properly placed organelles and enzyme complexes that are suspended from an intricate network of structural protein polymers termed the cytoskeleton. All movement of organelles and vesicles within the cell is regulated by this cytoskeleton, and it is clear that the cytoskeleton is responsible for all of the cell's external movement as well. In this lecture, we will consider how the cytoskeleton elicits cell migration.The three main elements of the cytoskeleton are microtubules, intermediate filaments, and actin filaments. Microtubules are essential for (a) intracellular transport within the cytoplasm and transport between the nucleus and cytoplasm, (b) the structure and movement of all cilia and flagella, and (c) the structure of the mitotic spindle and movement of chromosomes on the spindle during cell division. Intermediate filaments give structural integrity to virtually all cells and tissues by providing an intracellular network of flexible cables that strengthen internal cell structure and stabilize cell-to-cell adhesion. It is this intercellular binding property that stably joins epithelial cells together to provide the protective functions of skin and the integrity of the intestinal mucosa.Actin is a highly conserved protein ubiquitous to all eukaryotic cells. Actin is absolutely required for (a) cell migration, (b) the contraction of muscle (both striated and smooth), (c) the structure and function of many cell protrusions (e.g., microvilli, filopodia, lamellopodia, blood platelet projections), (d) division of the cytoplasm (cytokinesis) during telophase of cell mitosis, and (e) movement and placement of organelles within the cell. Actin filaments are also called thin filaments because of their very slender (70 Ã…) diameter.

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Morgan & Claypool Publishers

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ISBN 10

1615040064

ISBN 13

9781615040063

A Primer on Ugaritic

Language, Culture and Literature

By: William M. Schniedewind,Joel H. Hunt

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A Primer on Ugaritic

Language, Culture and Literature

By: William M. Schniedewind,Joel H. Hunt

A Primer on Ugaritic is an introduction to the language of the ancient city of Ugarit, a city that flourished in the second millennium BCE on the Lebanese coast, placed in the context of the culture, literature, and religion of this ancient Semitic culture. The Ugaritic language and literature was a precursor to Canaanite and serves as one of our most important resources for understanding the Old Testament and the Hebrew language. Special emphasis is placed on contextualization of the Ugaritic language and comparison to ancient Hebrew as well as Akkadian. The book begins with a general introduction to ancient Ugarit, and the introduction to the various genres of Ugaritic literature is placed in the context of this introduction. The language is introduced by genre, beginning with prose and letters, proceeding to administrative, and finally introducing the classic examples of Ugaritic epic. A summary of the grammar, a glossary, and a bibliography round out the volume.

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218

Publisher

Cambridge University Press

Published Date

ISBN 10

1139466984

ISBN 13

9781139466981

Rhoda: ‘Comrade Kadalie, You Are Out of Order!’

A Biography

By: Joel B Pollak

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Rhoda: ‘Comrade Kadalie, You Are Out of Order!’

A Biography

By: Joel B Pollak

This authorized biography was made possible through the gracious help of my mother-in-law, Rhoda Kadalie, who provided generous access to her files, letters, photographs, and extensive library of documents. She made time to sit with me for several hours of interviews from September through October 2021, to answer questions as they arose, and to offer innumerable clarifications. Rhoda also reviewed the first draft of the biography in December 2021, making corrections and additions, and contributing some of her own original vignettes, never before published.

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616

Publisher

UJ Press

Published Date

ISBN 10

1776413482

ISBN 13

9781776413485

The City

A Global History

By: Joel Kotkin

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The City

A Global History

By: Joel Kotkin

If humankind can be said to have a single greatest creation, it would be those places that represent the most eloquent expression of our species’s ingenuity, beliefs, and ideals: the city. In this authoritative and engagingly written account, the acclaimed urbanist and bestselling author examines the evolution of urban life over the millennia and, in doing so, attempts to answer the age-old question: What makes a city great? Despite their infinite variety, all cities essentially serve three purposes: spiritual, political, and economic. Kotkin follows the progression of the city from the early religious centers of Mesopotamia, the Indus Valley, and China to the imperial centers of the Classical era, through the rise of the Islamic city and the European commercial capitals, ending with today’s post-industrial suburban metropolis. Despite widespread optimistic claims that cities are “back in style,” Kotkin warns that whatever their form, cities can thrive only if they remain sacred, safe, and busy–and this is true for both the increasingly urbanized developing world and the often self-possessed “global cities” of the West and East Asia. Looking at cities in the twenty-first century, Kotkin discusses the effects of developments such as shifting demographics and emerging technologies. He also considers the effects of terrorism–how the religious and cultural struggles of the present pose the greatest challenge to the urban future. Truly global in scope, The City is a timely narrative that will place Kotkin in the company of Lewis Mumford, Jane Jacobs, and other preeminent urban scholars.

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172

Publisher

Modern Library

Published Date

ISBN 10

0307432041

ISBN 13

9780307432049

The Composition of the Pentateuch

Renewing the Documentary Hypothesis

By: Joel S. Baden

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The Composition of the Pentateuch

Renewing the Documentary Hypothesis

By: Joel S. Baden

For well over two centuries the question of the composition of the Pentateuch has been among the most central and hotly debated issues in the field of biblical studies. In this book, Joel Baden presents a fresh and comprehensive argument for the Documentary Hypothesis. Critically engaging both older and more recent scholarship, he fundamentally revises and reorients the classical model of the formation of the Pentateuch. Interweaving historical and methodological chapters with detailed textual case studies, Baden provides a critical introduction to the history of Pentateuchal scholarship, discussions on the most pressing issues in the current debate, and a practical model for the study of the biblical text.

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393

Publisher

Yale University Press

Published Date

ISBN 10

0300152639

ISBN 13

9780300152630

The World on a Plate

A Tour Through the History of America's Ethnic Cuisine

By: Joel Denker

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The World on a Plate

A Tour Through the History of America's Ethnic Cuisine

By: Joel Denker

A food and travel writer draws on a series of interviews with ethnic food merchants, including importers, restaurateurs, grocers, vendors, and manufacturers, to explore the diverse ways in which immigrants from every corner of the world have transformed and shaped American culinary traditions. Reprint.

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220

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U of Nebraska Press

Published Date

ISBN 10

0803260148

ISBN 13

9780803260146

John the Baptist in History and Theology

By: Joel Marcus

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John the Baptist in History and Theology

By: Joel Marcus

An analysis that challenges the conventional Christian hierarchy of John the Baptist and Jesus of Nazareth While the Christian tradition has subordinated John the Baptist to Jesus of Nazareth, John himself would likely have disagreed with that ranking. In this eye-opening new book, John the Baptist in History and Theology, Joel Marcus makes a powerful case that John saw himself, not Jesus, as the proclaimer and initiator of the kingdom of God and his own ministry as the center of God's saving action in history. Although the Fourth Gospel has the Baptist saying, "He must increase, but I must decrease," Marcus contends that this and other biblical and extrabiblical evidence reveal a continuing competition between the two men that early Christians sought to muffle. Like Jesus, John was an apocalyptic prophet who looked forward to the imminent end of the world and the establishment of God's rule on earth. Originally a member of the Dead Sea Sect, an apocalyptic community within Judaism, John broke with the group over his growing conviction that he himself was Elijah, the end-time prophet who would inaugurate God's kingdom on earth. Through his ministry of baptism, he ushered all who came to him—Jews and non-Jews alike—into this dawning new age. Jesus began his career as a follower of the Baptist, but, like other successor figures in religious history, he parted ways from his predecessor as he became convinced of his own centrality in God's purposes. Meanwhile John's mass following and apocalyptic message became political threats to Herod Antipas, who had John executed to abort any revolutionary movement. Based on close critical-historical readings of early texts—including the accounts of John in the Gospels and in Josephus's Antiquities—as well as parallels from later religious movements, John the Baptist in History and Theology situates the Baptist within Second Temple Judaism and compares him to other apocalyptic thinkers from ancient and modern times. It concludes with thoughtful reflections on how its revisionist interpretations might be incorporated into the Christian faith.

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289

Publisher

Univ of South Carolina Press

Published Date

ISBN 10

1611179017

ISBN 13

9781611179019

Radical Evolution

The Promise and Peril of Enhancing Our Minds, Our Bodies -- and What It Means to Be Human

By: Joel Garreau

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Radical Evolution

The Promise and Peril of Enhancing Our Minds, Our Bodies -- and What It Means to Be Human

By: Joel Garreau

Taking us behind the scenes with today’s foremost researchers and pioneers, bestselling author Joel Garreau shows that we are at a turning point in history. At this moment we are engineering the next stage of human evolution. Through advances in genetic, robotic, information, and nanotechnologies, we are altering our minds, our memories, our metabolisms, our personalities, our progeny–and perhaps our very souls. Radical Evolution reveals that the powers of our comic-book superheroes already exist, or are in development in hospitals, labs, and research facilities around the country–from the revved-up reflexes and speed of Spider-Man and Superman, to the enhanced mental acuity and memory capabilities of an advanced species. Over the next fifteen years, Garreau makes clear in this New York Times Book Club premiere selection, these enhancements will become part of our everyday lives. Where will they lead us? To heaven–where technology’s promise to make us smarter, vanquish illness, and extend our lives is the answer to our prayers? Or, as some argue, to hell–where unrestrained technology brings about the ultimate destruction of our species?

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402

Publisher

Crown

Published Date

ISBN 10

0767915038

ISBN 13

9780767915038

In the Beginning

A Short History of the Hebrew Language

By: Joel Hoffman

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In the Beginning

A Short History of the Hebrew Language

By: Joel Hoffman

Written in language simple enough for everyone to learn, this sweeping history traces the Hebrew language's development and covers the dramatic story of the rebirth of Hebrew as a modern, spoken language.

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278

Publisher

NYU Press

Published Date

ISBN 10

0814736904

ISBN 13

9780814736906

The Book of Exodus

A Biography

By: Joel S. Baden

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The Book of Exodus

A Biography

By: Joel S. Baden

An essential biography of one of the Bible’s most powerful and inspiring books Exodus is the second book of the Hebrew Bible, but it may rank first in lasting cultural importance. It is here that the classic biblical themes of oppression and redemption, of human enslavement and divine salvation, are most dramatically expressed. Joel Baden tells the story of this influential and enduring book, tracing how its famous account of the Israelites’ journey to the promised land has been adopted and adapted for millennia, often in unexpected ways. Baden draws a distinction between the Exodus story and the book itself, which is one of the most multifaceted in the Bible, containing poems, law codes, rituals, and architectural plans. He shows how Exodus brings together an array of oral and written traditions from the ancient Middle East, and how it came to be ritualized in the Passover Seder and the Eucharist. Highlighting the remarkable resilience and flexibility of Exodus, Baden sheds light on how the bestowing of the Torah to Moses on Mount Sinai divided Jewish and Christian thinkers, on the importance of Exodus during the Reformation and the American Revolution, and on its uses in debates for and against slavery. He also traces how the defining narrative of ancient Israel helped to define Mormon social identity, the American civil rights movement, and liberation theology. Though three thousand years old, the Exodus—as history, as narrative, as metaphor, as model—continues to be vitally important for us today. Here is the essential biography of this incomparable spiritual masterpiece.

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255

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Princeton University Press

Published Date

ISBN 10

0691169543

ISBN 13

9780691169545

Book's by Joel Pardee

Cell Origin, Structure, and Function

Cell Origin, Structure, and Function

Understanding Breast Cancer

Understanding Breast Cancer

America

America

Wild Ride

Wild Ride

The Actin Cytoskeleton in Cell Motility, Cancer, and Infection

The Actin Cytoskeleton in Cell Motility, Cancer, and Infection

A Primer on Ugaritic

A Primer on Ugaritic

Rhoda: ‘Comrade Kadalie, You Are Out of Order!’

Rhoda: ‘Comrade Kadalie, You Are Out of Order!’

The City

The City

The Composition of the Pentateuch

The Composition of the Pentateuch

The World on a Plate

The World on a Plate

John the Baptist in History and Theology

John the Baptist in History and Theology

Radical Evolution

Radical Evolution

In the Beginning

In the Beginning

The Book of Exodus

The Book of Exodus

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