Joe W. Gray's Books

The Molecular Basis of Cancer

Expert Consult - Online

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

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The Molecular Basis of Cancer

Expert Consult - Online

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.

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Page Count

1948

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1437710999

ISBN 13

9781437710991

The Molecular Basis of Cancer E-Book

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

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The Molecular Basis of Cancer E-Book

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. - Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. - Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. - Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. - Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. - Access the entire text and illustrations online, fully searchable, at Expert Consult.

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Page Count

1040

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323261965

ISBN 13

9780323261968

Techniques in Cell Cycle Analysis

By: Joe W. Gray,Zbigniew Darzynkiewicz

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Techniques in Cell Cycle Analysis

By: Joe W. Gray,Zbigniew Darzynkiewicz

Quantification of the proliferative characteristics of normal and malignant cells has been of interest to oncolo gists and cancer biologists for almost three decades. This interest stems from (a) the fact that cancer is a disease of uncontrolled proliferation, (b) the finding that many of the commonly used anticancer agents are preferentially toxic to cells that are actively proliferating, and (c) the observa tion that significant differences in proliferation characteristics exist between normal and malignant cells. Initially, cell cycle analysis was pursued enthusiastically in the hope of gener ating information useful for the development of rational cancer therapy strategies; for example, by allowing identi fication of rapidly proliferating tumors against which cell cycle-specific agents could be used with maximum effec tiveness and by allowing rational scheduling of cell cyc- specific therapeutic agents to maximize the therapeutic ratio. Unfortunately, several difficulties have prevented realiza tion of the early promise of cell cycle analysis: Proliferative patterns of the normal and malignant tissues have been found to be substantially more complex than originally an ticipated, and synchronization of human tumors has proved remarkably difficult. Human tumors of the same type have proved highly variable, and the cytokinetic tools available for cell cycle analysis have been labor intensive, as well as somewhat subjective and in many cases inapplicable to humans. However, the potential for substantially improved cancer therapy remains if more accurate cytokinetic infor mation about human malignancies and normal tissues can be obtained in a timely fashion.

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Page Count

419

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1603274065

ISBN 13

9781603274067

Grass

In Search of Human Habitat

By: Joe C. Truett

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Grass

In Search of Human Habitat

By: Joe C. Truett

Part autobiography, part philosophical rumination, this evocative conservation odyssey explores the deep affinities between humans and our original habitat: grasslands. In a richly drawn, anecdotally driven narrative, Joe C. Truett, a grasslands ecologist who writes with a flair for language, traces the evolutionary, historical, and cultural forces that have reshaped North American rangelands over the past two centuries. He introduces an intriguing cast of characters—wildlife and grasslands biologists, archaeologists, ranchers, and petroleum geologists—to illuminate a wide range of related topics: our love affair with turf and how it manifests in lawns and sports, the ecological and economic dimensions of ranching, the glory of cowboy culture, grasslands and restoration ecology, and more. His book ultimately provides the background against which we can envision a new paradigm for restoring rangeland ecosystems—and a new paradigm for envisioning a more sustainable future.

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Page Count

237

Publisher

Univ of California Press

Published Date

ISBN 10

0520944526

ISBN 13

9780520944527

Book's by Joe W. Gray

The Molecular Basis of Cancer

The Molecular Basis of Cancer

The Molecular Basis of Cancer E-Book

The Molecular Basis of Cancer E-Book

Techniques in Cell Cycle Analysis

Techniques in Cell Cycle Analysis

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