Joaquim M.S. Cabral's Books

Stem Cell Bioprocessing

For Cellular Therapy, Diagnostics and Drug Development

By: Tiago G. Fernandes,M. Margardia Diogo,Joaquim M.S. Cabral

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Stem Cell Bioprocessing

For Cellular Therapy, Diagnostics and Drug Development

By: Tiago G. Fernandes,M. Margardia Diogo,Joaquim M.S. Cabral

Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. - Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approaches - Envisages the use of stem cells in regenerative medicine and drug screening applications - Discusses the application of microscale techniques as a tool to perform basic stem cell biology studies

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Page Count

236

Publisher

Elsevier

Published Date

ISBN 10

1908818301

ISBN 13

9781908818300

Stem Cell Bioprocessing

For Cellular Therapy, Diagnostics and Drug Development

By: Tiago G. Fernandes,M. Margardia Diogo,Joaquim M.S. Cabral

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Stem Cell Bioprocessing

For Cellular Therapy, Diagnostics and Drug Development

By: Tiago G. Fernandes,M. Margardia Diogo,Joaquim M.S. Cabral

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236

Publisher

Elsevier

Published Date

ISBN 10

1908818301

ISBN 13

9781908818300

Immobilised Enzymes and Cells

By: A Rosevear,J.F Kennedy,Joaquim M.S. Cabral

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Immobilised Enzymes and Cells

By: A Rosevear,J.F Kennedy,Joaquim M.S. Cabral

During the past twenty years the immobilisation of enzymes and cells has developed into a major topic of theoretical and practical importance. This technology unites the disciplines of chemistry, biochemistry and cell biology on one hand with biochemical and process engineering on the other. As well as having an importance in its own right, its use has already made an impact on downstream processing of biochemicals. In this handbook the authors, who are experts in their field, bring together for the first time in a single volume information on the techniques of immobilisation and the uses of the immobilised enzymes and cells. They provide an overview of the subject, as well as practical guidance on the choice and relative merits of many techniques. Carefully selected examples taken from the literature illustrate the general principles. The balance between theory and practice provides a text which will introduce the topic to research students and also provide a source of practical details on efficient immobilisation methods for workers who's only interest is in exploiting the methods in their particular field. This is primarily a laboratory book, and as such it should be found dog-eared and stained on a laboratory bench rather than gathering dust on a library shelf. Key references are given to enable the reader to explore the literature in depth. Information is also supplied on journals, enzyme and equipment suppliers.

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Page Count

248

Publisher

CRC Press

Published Date

ISBN 10

085274515X

ISBN 13

9780852745151

Book's by Joaquim M.S. Cabral

Stem Cell Bioprocessing

Stem Cell Bioprocessing

Stem Cell Bioprocessing

Stem Cell Bioprocessing

Immobilised Enzymes and Cells

Immobilised Enzymes and Cells

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