Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy, 3rd Edition, includes clinical trial results of more than 250 state-of-the-art targeted therapy and immunotherapy agents, providing a practical, intuitive, colorful overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Daniel D. Karp, Gerald S. Falchook, and JoAnn D. Lim, helps you navigate through the newest research reports and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of investigational targeted agents and combinations of agents. This handbook presents information distilled by dozens of translational research clinicians and other healthcare experts with hundreds of years of cumulative experience in the revolutionary area of genomically based precision oncology.
Written by and for Nurse Practitioners from a unique collaborative perspective, Primary Care: A Collaborative Practice, 4th Edition, prepares you to provide care for all of the major disorders of adults seen in the outpatient setting. Evidence-based content reflects the latest guidelines for primary care of hundreds of conditions, including hypertension, diabetes, and sexually transmitted infections. Now in full color, the 4th Edition includes chapters on emerging topics such as genetics, obesity, lifestyle management, and emergency preparedness. Combining a special blend of academic and clinical expertise, the author team provides a practical text/reference that promotes a truly collaborative primary care practice. Comprehensive, evidence-based content incorporates the latest standardized guidelines for primary care in today's fast-paced, collaborative environment. Unique! A collaborative perspective, reflecting the key roles of NPs, MDs, PAs, PharmDs, and others, promotes seamless continuity of care. A consistent format from chapter to chapters facilitates learning and clinical reference value. Diagnostics and Differential Diagnosis boxes provide a quick reference for diagnosing disorders and helping to develop effective management plans. Physician Consultation icons highlight situations or conditions in which consultation is either recommended or necessary. Emergency Referral icons identify signs and symptoms that indicate the need for immediate referral to an emergency facility. Co-management with Specialists discussions help you provide truly collaborative care in the outpatient setting. Complementary and alternative therapies are addressed where supported by solid research evidence.
Financial econometrics is a great success story in economics. Econometrics uses data and statistical inference methods, together with structural and descriptive modeling, to address rigorous economic problems. Its development within the world of finance is quite recent and has been paralleled by a fast expansion of financial markets and an increasing variety and complexity of financial products. This has fueled the demand for people with advanced econometrics skills. For professionals and advanced graduate students pursuing greater expertise in econometric modeling, this is a superb guide to the field's frontier. With the goal of providing information that is absolutely up-to-date—essential in today's rapidly evolving financial environment—Gourieroux and Jasiak focus on methods related to foregoing research and those modeling techniques that seem relevant to future advances. They present a balanced synthesis of financial theory and statistical methodology. Recognizing that any model is necessarily a simplified image of reality and that econometric methods must be adapted and applied on a case-by-case basis, the authors employ a wide variety of data sampled at frequencies ranging from intraday to monthly. These data comprise time series representing both the European and North American markets for stocks, bonds, and foreign currencies. Practitioners are encouraged to keep a critical eye and are armed with graphical diagnostics to eradicate misspecification errors. This authoritative, state-of-the-art reference text is ideal for upper-level graduate students, researchers, and professionals seeking to update their skills and gain greater facility in using econometric models. All will benefit from the emphasis on practical aspects of financial modeling and statistical inference. Doctoral candidates will appreciate the inclusion of detailed mathematical derivations of the deeper results as well as the more advanced problems concerning high-frequency data and risk control. By establishing a link between practical questions and the answers provided by financial and statistical theory, the book also addresses the needs of applied researchers employed by financial institutions.
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