Based on the past 30-years' research on the technical and cultural values of China's Grand Canal, this book, based on interdisciplinary research, studies the natural and social background of the evolution and development of different sections of the Grand Canal in different historical periods, as well as the interrelations between the Grand Canal and the Chinese politics, economics, and culture. It also assesses the effects of the Grand Canal on the progress of the Chinese civilization, engineering technology achievement, the natural environment, and the society, providing the readers with an understanding of China's Grand Canal from the perspectives of hydraulic engineering and history.
Hyperglycemia refers to a condition in which an excessive amount of glucose circulates in the blood plasma. A wide range of evidence has proved hyperglycemia to be a great inducer of reactive oxygen species (ROS), through which various processes and signaling transduction cascades are activated or inhibited. Bursts of ROS can be produced by mitochondria, NADPH oxidase, and xanthine oxidase under hyperglycemia. These excessive ROS will further cause oxidative stress and contribute to the development of hyperglycemia complications. One of the downstream processes affected by redox imbalance is autophagy. Increasing evidence shows disturbed autophagy in cell lines treated with high glucose or in animals under hyperglycemia. The signaling pathways involved in are quite controversial, however. Here, we focus on the ROS-ERK/JNK-p53 pathway and discuss its potential role in activating autophagy in the condition of hyperglycemia.
This book discusses the features of composite materials and arch structures. Providing an in-depth fundamental and practical guide to the field, it systemically addresses all aspects of concrete-filled steel tubular (CFST) arch bridges, including a comprehensive overview on technical developments, structural systems, structural detailing, design and analysis, construction technology, and maintenance. The real-world examples presented have been carefully selected to highlight the advanced theoretical and technological solutions for CFST arch bridges and to motivate researchers to promote innovative and sustainable development in the area. The book couples fundamental concepts with advanced practices translated from the third edition of the author’s Chinese book on CFST arch bridges, which has been the most significant book on the topic since the first edition published in 1999. This English translation can servers as an idea textbook for postgraduate students in the fields of civil, construction and environmental engineering, especially in bridge engineering, as well as a perfect review and reference guide for engineering practitioners and researchers.
Based on the past 30-years' research on the technical and cultural values of China's Grand Canal, this book, based on interdisciplinary research, studies the natural and social background of the evolution and development of different sections of the Grand Canal in different historical periods, as well as the interrelations between the Grand Canal and the Chinese politics, economics, and culture. It also assesses the effects of the Grand Canal on the progress of the Chinese civilization, engineering technology achievement, the natural environment, and the society, providing the readers with an understanding of China's Grand Canal from the perspectives of hydraulic engineering and history.
This book discusses the features of composite materials and arch structures. Providing an in-depth fundamental and practical guide to the field, it systemically addresses all aspects of concrete-filled steel tubular (CFST) arch bridges, including a comprehensive overview on technical developments, structural systems, structural detailing, design and analysis, construction technology, and maintenance. The real-world examples presented have been carefully selected to highlight the advanced theoretical and technological solutions for CFST arch bridges and to motivate researchers to promote innovative and sustainable development in the area. The book couples fundamental concepts with advanced practices translated from the third edition of the author’s Chinese book on CFST arch bridges, which has been the most significant book on the topic since the first edition published in 1999. This English translation can servers as an idea textbook for postgraduate students in the fields of civil, construction and environmental engineering, especially in bridge engineering, as well as a perfect review and reference guide for engineering practitioners and researchers.
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