Starting from the intraprocedural basic case, this monograph focuses on interprocedural optimization. It emphasizes the analogies and essential differences between intraprocedural and interprocedural optimization, and offers cookbook style support for constructing the underlying algorithms. It is aimed at compiler constructors and researchers interested in the systematic transfer of intraprocedural optimizations to the interprocedural setting, as well as students seeking a gentle introduction to the field.
In-vivo imaging markers of neuronal changes related to Alzheimer’s disease (AD) are ideally suited to be employed as diagnostic markers for early and differential diagnosis of AD as well as for the assessment of neurobiological effects of medical treatments in clinical trials. Novel molecular imaging techniques enable in-vivo detection of cerebral amyloid pathology, whereas magnetic resonance imaging (MRI)-based techniques, such as volumetric MRI and diffusion tensor imaging (DTI), provide structural lesion markers that allow tracking disease progression from preclinical through predementia to clinically manifest stages of AD. However, a widespread clinical use of these imaging biomarkers is hampered by considerable multi-centric variability related to differences in scanner hardware and acquisition protocols, but also by the lack of internationally agreed upon standards for analytic design and employed quantitative metrics. Several strategies for reducing multicenter variability in imaging measures have been proposed, including homogenization of the acquisition settings across scanner platforms, stringent quality assurance procedures, and artifact removal by means of post-acquisition image processing techniques. In addition, selection of appropriate statistical models to account for remaining multicenter variability in the data can further improve the accuracy and reproducibility of study results. The first projects for international standardization of image analysis methods and derived quantitative metrics have emerged recently for volumetric MRI measures. In contrast, the standardization and establishment of DTI-derived measures within a multicenter context are less well developed. Although molecular imaging techniques are already widely used in multicenter settings, sources of variability across sites and appropriate methods to reduce multicenter effects are still not explored in detail. Comparability of neuroimaging measures as AD biomarkers in worldwide clinical settings will finally depend on the establishment of internationally agreed upon standards for image acquisition, quality assurance, and employed quantitative metrics.
In 1935-40 and again in 1947, the Iranian Expedition of the Metropolitan Museum excavated the city of Nishapur, a flourishing center in medieval times located in eastern Iran. This is the fourth volume in a series dedicated to publishing the finds. It presents a survey of glass of the early Islamic period throughout the Near East, discusses the significance of the Nishapur glass findings, and provides a catalogue of the finds with a focus on glass-decorating techniques. Map and site plans, a glossary, a concordance, and an extensive bibliography are included. Annotation copyright by Book News, Inc., Portland, OR
This textbook teaches important material and technological fundamentals in various technical systems and applied geoscientific fields. Beginning with the mineralogical characteristics of selected non-metallic raw materials and industrial minerals, this book presents the connections between properties and industrial applications and discusses the environment-relevant aspects as well as problems of biomineralogy. An introduction is given to important mineralogical and physico-chemical aspects of ceramic materials such as silicate ceramics, glass, cement, refractory materials as well as an overview about material synthesis. This makes it the first textbook to present the fundamentals of applied mineralogy as a material-related geoscience in a compact form and to show important bridges to industrial issues and approaches to solutions. It is aimed primarily at undergraduate students of geosciences and materials science, but is also suitable for related disciplines and practical applications.
A practical, full-color guide to optical manufacturing Featuring more than 300 full-color photos and illustrations, Optical Technology describes the basics of optics and optical materials and the methods and applications of optical manufacturing and assembly. Important procedures for the production of optical components and systems are examined in detail. Real-world examples demonstrate the potential of various manufacturing procedures, and end-of-chapter questions reinforce key concepts. This is an invaluable resource for optical designers and fabrication engineers and also a well-rounded introduction to optics and optical technology. On the book's website are more than two hours of video featuring selected fabrication and assembly techniques, plus SagCalc, a practical fabrication-specific software. Optical Technology covers: Development of glass and optical production Basics of optics Optical materials, including mineral glass, organic glass, and crystals Foundations of the manufacturing process Primary forming of optical glass Transforming methods Cutting processes, including dividing, grinding, drilling, lapping, polishing, and centering Ultra-precision processing, structuring, and cleaning Coating with protective and optical layers Material property changes, such as annealing, strengthening, aging, coloration, and phototropic effects Joining processes, including blocking, clamping, and connecting optical elements Selecting fabrication technologies based on required specifications
Starting from the intraprocedural basic case, this monograph focuses on interprocedural optimization. It emphasizes the analogies and essential differences between intraprocedural and interprocedural optimization, and offers cookbook style support for constructing the underlying algorithms. It is aimed at compiler constructors and researchers interested in the systematic transfer of intraprocedural optimizations to the interprocedural setting, as well as students seeking a gentle introduction to the field.
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