The streets are a battleground for humans, vampires, and demons alike—where survival is a skill, love is a weapon, and the most dangerous act is to care for another . . . Keir is an assassin devoted to Lady Arianne, the last of her royal bloodline. He is sworn to protect her, and that means eliminating any threat to her life. But while on a mission, he is set upon by a pack of demons, barely escaping with his life. Cleopatra lives by a set of rules so rigid she no longer knows her true self. But her kind and loving nature resurfaces when she finds a man, bloodied and dying. Moved to help him, she risks her future and her life to save a stranger far below her aristocratic station. Their attraction to each other is as powerful as it is forbidden. But even as their love grows, Keir keeps his true identity a secret—and this lie is not the only threat to their love . . . or their lives.
Winter skiing, spring wildflowers, summertime beaches, or autumnal foliage: no matter the season, Moon Maine, Vermont & New Hampshire reveals the best of these New England gems. Inside you'll find: Strategic, flexible itineraries designed for outdoor adventurers, history buffs, foodies, and more, including a week-long road trip covering Maine, Vermont, and New Hampshire The top sights and unique experiences: See the fall foliage paint the landscape red and gold, and wander through a small-town harvest festival. Wade through tide pools in Acadia National Park, or hike the rocky landscapes of White Mountains. Sip your way through Burlington's breweries, or sample local flavors at the Brattleboro farmers market. Catch the sunrise at a picturesque lighthouse, relax on miles of sandy coastline, and line up with the locals for lobster rolls, fresh-shucked oysters, and fried clams. Go skiing in the Green Mountains, or cozy up for an old-fashioned sleigh ride through the snow Honest advice on when to go, where to stay, and how to get around from Vermont local Jen Rose Smith Full-color, vibrant photos and detailed maps throughout Thorough background on the wildlife, landscape, climate, and local culture Recommendations for families, international visitors, travelers with disabilities, and more With Moon Maine, Vermont & New Hampshire's expert tips and local know-how, you can plan your trip your way. Hitting the road? Try Moon New England Road Trip.
Praise for the First Edition of Design and Analysis of Clinical Trials "An excellent book, providing a discussion of the clinical trial process from designing the study through analyzing the data, and to regulatory requirement . . . could easily be used as a classroom text to understand the process in the new drug development area." –Statistical Methods in Medicine A complete and balanced presentation now revised, updated, and expanded As the field of research possibilities expands, the need for a working understanding of how to carry out clinical trials only increases. New developments in the theory and practice of clinical research include a growing body of literature on the subject, new technologies and methodologies, and new guidelines from the International Conference on Harmonization (ICH). Design and Analysis of Clinical Trials, Second Edition provides both a comprehensive, unified presentation of principles and methodologies for various clinical trials, and a well-balanced summary of current regulatory requirements. This unique resource bridges the gap between clinical and statistical disciplines, covering both fields in a lucid and accessible manner. Thoroughly updated from its first edition, the Second Edition of Design and Analysis of Clinical Trials features new topics such as: Clinical trials and regulations, especially those of the ICH Clinical significance, reproducibility, and generalizability Goals of clinical trials and target population New study designs and trial types Sample size determination on equivalence and noninferiority trials, as well as comparing variabilities Also, three entirely new chapters cover: Designs for cancer clinical trials Preparation and implementation of a clinical protocol Data management of a clinical trial Written with the practitioner in mind, the presentation assumes only a minimal mathematical and statistical background for its reader. Instead, the writing emphasizes real-life examples and illustrations from clinical case studies, as well as numerous references-280 of them new to the Second Edition-to the literature. Design and Analysis of Clinical Trials, Second Edition will benefit academic, pharmaceutical, medical, and regulatory scientists/researchers, statisticians, and graduate-level students in these areas by serving as a useful, thorough reference source for clinical research.
Building Science Graphics: An illustrated guide to communicating science through diagrams and visualizations is a practical guide for anyone—regardless of previous design experience and preferred drawing tools—interested in creating science-centric illustrated explanatory diagrams. Starting with a clear introduction to the concept of information graphics and their role in contemporary science communication, it then outlines a process for creating graphics using evidence-based design strategies. The heart of the book is composed of two step-by-step graphical worksheets, designed to help jump-start any new project. This is both a textbook and a practical reference for anyone that needs to convey scientific information in an illustrated form for articles, poster presentations, slide shows, press releases, blog posts, social media posts and beyond.
One of the funniest voices in the inspirational genre."--Booklist Lucetta Plum is an actress on the rise in New York City, but is forced to abandon her starring role when a fan's interest turns threatening. Lucetta's widowed friend, Abigail Hart, is delighted at the opportunity to meddle in Lucetta's life and promptly whisks her away to her grandson's estate to hide out. Bram Haverstein may appear to simply be a somewhat eccentric gentleman of means, but a mysterious career and a secret fascination with a certain actress mean there's much more to him than society knows. Lucetta, who has no interest in Abigail's matchmaking machinations, has the best intentions of remaining cordial but coolly distant to Bram. But when she can't ignore the strange and mysterious things going on in his house, it'll take more than good intentions to keep her from trying to discover who Bram is behind the part he plays.
Explore the best of New England's historic cities, admire the famed fall foliage, and stroll the stunning coastline with Moon New England. Inside you'll find: Flexible itineraries for every season, including quick weekend getaways from Boston and New York and two weeks exploring all of New England Strategic advice for foliage-seekers, beach bums, winter sports enthusiasts, foodies, and more Can't-miss highlights and unique experiences: Catch America's first sunrise at Acadia, or hike the rocky landscape of the White Mountain Peaks. Sample your way through craft breweries, or sip chowder in America's oldest restaurant. Explore rolling dunes and sandy beaches at Cape Cod, and find the best local seafood shack for lobster rolls, fresh-shucked oysters, and piles of fried clams. Follow in the footsteps of the founders on Boston's Freedom Trail, or gaze at glamorous 19th-century mansions in Newport. Hit the top slopes in the region for skiing and snowboarding, or watch the changing leaves paint the landscape in red and gold Expert advice from Vermont local Jen Rose Smith on when to go, where to stay, and how to get around Full-color photos and detailed regional and city maps throughout Thorough background on the wildlife, landscape, climate, and local culture Recommendations for families with children, international visitors, seniors, travelers with disabilities, and more Focused coverage of Boston, Cape Cod and the Islands, the Berkshires, Connecticut, Rhode Island, Vermont, New Hampshire's Seacoast and Lakes Region, New Hampshire's White Mountains, Coastal Maine, and Acadia National Park With Moon New England's practical tips and local know-how, you can plan your trip your way. Hitting the road? Try Moon New England Road Trip. Looking for more New England? Try Moon Boston or Moon Vermont.
While many people think true crime is a new phenomenon, Americans have been obsessed with the genre for over a century, and popular culture continuously tries to cash in. The names of infamous serial killers are well-known, but the identities of their often-female victims are frequently lost to history. This text flips the script and focuses on the women to keep their identities known and remembered. This is the first book to examine how popular culture has mistreated women as both perpetrators and victims of crime, covering a hundred-year span from 1920 to 2020. Detailed is popular culture's interest in true crime and how women in true crime documentation have largely been sexualized and victim-blamed over the decades.
A reporter uncovers the rest of the story In More After the Break, Jen Maxfield revisits ten memorable stories from her career as a TV news reporter, describing in heart-pounding detail how the events unfolded and revealing what happened after the cameras went away. She introduces readers to unforgettable people who will inspire you with their hopefulness, even when confronting life’s greatest heartbreaks: a young man who lost both legs in a ferry crash, an endurance athlete with stage-four lung cancer, a fifth grader on a doomed field trip, an Ivy League undergrad sentenced to decades in prison, a young woman who gave her life for an animal, a Wall Street executive on an ill-fated bike ride, a preschooler whose health hinged on an immigration battle, a family who lost everything in a hurricane, a mother who fought back against domestic violence, and a man who stood up for his rights while seated in his wheelchair. Returning to find these people years—even decades—after she featured their stories on the news gives Maxfield an opportunity to ask the burning questions she had always pondered: What happened after the live truck pulled away? What is the rest of the story?
How can social movements help bring about large-scale systems change? This is the question Jen Gobby sets out to answer in More Powerful Together. As an activist, Gobby has been actively involved with climate justice, anti-pipeline, and Indigenous land defense movements in Canada for many years. As a researcher, she has sat down with folks from these movements and asked them to reflect on their experiences with movement building. Bringing their incredibly poignant insights into dialogue with scholarly and activist literature on transformation, Gobby weaves together a powerful story about how change happens. In reflecting on what’s working and what’s not working in these movements, taking inventory of the obstacles hindering efforts, and imagining the strategies for building a powerful movement of movements, a common theme emerges: relationships are crucial to building movements strong enough to transform systems. Indigenous scholarship, ecological principles, and activist reflections all converge on the insight that the means and ends of radical transformation is in forging relationships of equality and reciprocity with each other and with the land. It is through this, Gobby argues, that we become more powerful together. 100% of the royalties made from the sales of this book are being donated to Indigenous Climate Action www.indigenousclimateaction.com
Much of the coverage surrounding the relationship between Indigenous communities and the Crown in Canada has focused on the federal, provincial, and territorial governments. Yet it is at the local level where some of the most important and significant partnerships are being made between Indigenous and non-Indigenous peoples. In A Quiet Evolution, Christopher Alcantara and Jen Nelles look closely at hundreds of agreements from across Canada and at four case studies drawn from Ontario, Quebec, and Yukon Territory to explore relationships between Indigenous and local governments. By analyzing the various ways in which they work together, the authors provide an original, transferable framework for studying any type of intergovernmental partnership at the local level. Timely and accessible, A Quiet Evolution is a call to politicians, policymakers and citizens alike to encourage Indigenous and local governments to work towards mutually beneficial partnerships.
From explorers’ accounts to boys’ adventure fiction, how Arctic exploration served as a metaphor for nation-building and empire in nineteenth-century Britain.
Civil Society has not been more relevant as a concept and a practice since the fall of communism in Eastern Europe. Global events from Tahir Square to Wall St have brought a new relevance and urgency to questions about the boundaries of legitimate dissent and public order policing, the meaning of tolerance in the context of conflicting rights claims, and how we can agree on the shared values of the ’good society’. This timely book examines the representation of civil society in news media, exploring the popular understanding of this contested space in relation to conflicting legitimating frames: as the neo-liberal Big Society, activist political participation, or postmodern apolitical tolerance. With close reference to prominent news stories, including the UK state visit of Pope Benedict XVI, anti-austerity protests and industrial action, police infiltration of the environmental movement, and the Occupy camp at St Paul’s Cathedral in London, News and Civil Society scrutinises different facets of contemporary civil society, civility and civic virtue. A cross-disciplinary engagement with questions of national identity and pluralism, civil liberties and dissent, power and accountability, this book will appeal to those with interests in media, journalism, sociology, citizenship and political studies.
New York Times bestselling author Jen Hatmaker believes that life can be fun, fulfilling, exciting, and beautiful. There's just one thing getting in the way: people. So many of our joys, struggles, thrills, and heartbreaks are connected to others, starting with ourselves and the people we came from. As we grow, our community does too. Before we know it, our lives are full of people: people we became friends with, married, birthed, live by, go to church with, don't like, don't understand, fear, and endlessly compare ourselves to. It's easy to lose our love for ourselves and for others, but what if we let people off the hook instead? What if we let go of the need to criticize ourselves and our neighbors? Jen shares the lessons she’s learned about how important it is to love people by teaching you how to: Break free of guilt and shame by dismantling the unattainable Pinterest life Learn to engage our culture's controversial issues with grace Release the burden of always being right and be liberated to love Identify the tools you already have, to develop real-life, all-in, know-my-junk-but-love-me-anyway friendships Escape our impossible standards for parenting and marriage by accepting the standard of "mostly good" Laugh until you cry In this raucous ride to freedom for modern women, Jen bares the refreshing wisdom, wry humor, no-nonsense faith, liberating insight, and fearless honesty that have made her beloved by women worldwide. Join Jen as she reminds you how amazing you are, how shockingly gracious God is, and how free we are to love others well and live the beautiful, wholehearted lives we were created to live.
Trivia Why's will make you trivia wise with these great features: 1) Over 2,000 questions with multiple-choice answers are each accompanied by a related factoid. Why is this answer correct (and not that one)? Why else is this person famous (or infamous)? Why was this event historically significant? 2) By cycling through six standard genus categories, this book makes an excellent supplement to your favorite trivia board game while providing a healthy variety of topics for your reading pleasure. Answers are hidden from view while the questions are being read and appear in the same block on the same side of the book two pages later. 3) Every question and answer has been carefully researched for accuracy and recently updated to include the latest available data. Since trivia is a moving target, however, updates and corrections will be posted to the triviawhys.com web site.
From snowy resorts and fall foliage to maple syrup and artisanal cheese, get to know the Green Mountain State with Moon Vermont. Inside you'll find: Strategic, flexible itineraries like a week touring the food scene, the great outdoors, and the best of the state, with ideas for families, foodies, outdoor adventurers, and more Must-see highlights and unique experiences: Wander through historic Montpelier, quirky Brattleboro, or charming Woodstock. Take a horse-drawn sleigh ride through fresh, fluffy snow, visit the woods that inspired Robert Frost, or stock up on flannels at an old-fashioned country store. Cruise the highway to see the stunning changing leaves, go cross-country skiing, hike a segment of the Long Trail, or cool off in a swimming hole. Dine at innovative restaurants serving forest-foraged cuisine and sample small-batch artisanal cheese, a flight of craft brews, and maple syrup Scenic drives in Vermont for viewing fall foliage, the best romantic getaways, and the top ski areas in the state Honest recommendations from Vermont local Jen Rose Smith on when to go, where to eat, and where to stay, from budget campgrounds to historic bed-and-breakfasts Full-color photos and detailed maps throughout Accurate, up-to-date information on the landscape, wildlife, and history Handy tips for international visitors, seniors, travelers with disabilities, and more With Moon Vermont's practical tips and local know-how, you can find your adventure. Expanding your trip? Try Moon Maine, Vermont & New Hampshire. Hitting the road? Check out Moon New England Road Trip.
How are metropolitan regions governed? What makes some regions more effective than others in managing policies that cross local jurisdictional boundaries? Political coordination among municipal governments is necessary to attract investment, rapid and efficient public transit systems, and to sustain cultural infrastructure in metropolitan regions. In this era of fragmented authority, local governments alone rarely possess the capacity to address these policy issues alone. This book explores the sources and barriers to cooperation and metropolitan policy making. It combines different streams of scholarship on regional governance to explain how and why metropolitan partnerships emerge and flourish in some places and fail to in others. It systematically tests this theory in the Frankfurt and Rhein-Neckar regions of Germany and the Toronto and Waterloo regions in Canada. Discovering that existing theories of metropolitan collective action based on institutions and opportunities are inconsistent, the author proposes a new theory of "civic capital", which argues that civic engagement and leadership at the regional scale can be important catalysts to metropolitan cooperation. The extent to which the actors hold a shared image of the metropolis and engage at that scale strongly influences the degree to which local authorities will be willing and able to coordinate policies for the collective development of the region. Metropolitan Governance and Policy will be of interest to students and scholars of comparative urban and metropolitan governance and sociology.
Life is messy for each of us. But Jen Hatmaker reminds us that it's okay to admit that we're all in the same boat. Join New York Times bestselling author and honorary big sister Jen as she shares hilarious tales, shameless honesty, and unconditional hope for the woman who's forgotten her moxie. We will endure discouragement, heartbreak, failure, and suffering. All of us. And more than once. But we are the very same folks who can experience triumph, perseverance, joy, and rebirth. More than once. And in more than one category. And in more than one season. And that? That's moxie. Moxie reaches for laughter, for courage, for the deep and important truth that women are capable of weathering the storm. We are not victims, we are not weak, we are not a sad, defeated group of sob sisters. Yes, life is hard, but we are incredibly resilient. Of Mess and Moxie shines a light on Jen's own triumphs and tragedies into a sigh of relief for all normal, fierce women everywhere. Whether it's the time she drove to the wrong city for a fourth-grade field trip or the way she learned to truly forgive, she offers a reminder to those of us who sometimes hide in the car eating crackers that we do actually have the moxie to get back up and face our messes head-on. After all, this race is not a contest--there's enough abundance to go around. This book will give you the encouragement you need to remember that: Your mess is normal You are not in competition with your peers--your seat at the table is secure You have incredible gifts to offer Come alongside Jen as she teaches us that we can all choose to live undaunted and in the moment, no matter what the moments hold, and we really can lead vibrant, courageous, grace-filled lives.
Provides a comprehensive summary of the continuously growing literature and research activities on the regulatory requirements, scientific and practical issues, and statistical methodology of the design and analysis of bioavailability and bioequivalence studies. Includes several new chapters.
From ancient woodland to wildflower blanketed meadows, lace up your trainers and explore the British countryside in 100 short runs. Following on from the National Trust's bestselling walks books, this has 100 short runs at NT properties and places around Britain. The routes travel through beautiful countryside of all kinds, from ancient woodland and meadows studded with wildflowers to rugged headlands with uninterrupted views of the sea. The runs are ideal for beginners as well as experienced runners looking for a more relaxed route. They range from 1 to 10 miles, with the vast majority being 6 miles (10k) max. Information on terrain and facilities is included, as are interesting points of history and natural history to look out for. The book also includes a section on training, gear and avoiding and dealing with injuries for beginners.
Quiet Rink always sits at the back of the classroom, away from the other children who have heard strange rumors about his family and prefer to keep their distance. But when a kind new girl joins his class, Rink's life begins to change. Inspired by the experiences of her brother, who is on the autism spectrum, Jen Wojtowicz's heartwarming tale encourages children to empathize with and reach out to others.
This book critically examines the development of the ‘stirring up hatred’ offences which are currently found within the UK’s Public Order Act 1986. Through a critical discourse analysis of key excerpts of parliamentary Hansard, the book constructs a detailed genealogy of the offences from the perspectives that shaped them. A novel application of theory on 'myth' is used to navigate the complex arguments and to trace ideas about identity and order across parliamentary debates, from fears of Fascism in the 1930s to condemnations of homophobia in the early 21st century. The story of the stirring up hatred offences told in this book therefore extends far beyond the traditional frame of a dilemma between regulating hate speech and safeguarding free speech: it is inextricably entwined with myths about law, race and national identity, and speaks to wider themes of coloniality, neoliberalism, white entitlement, British-Christian exceptionalism and the innocence of law. Written in an accessible and engaging style, this book challenges a wide range of assumptions about hate speech law and raises a series of considerations for developing forms of accountability that are less complicit in the harms that they are supposed to redress.
What's a superheroine to do when her super soldier ex turns up alive after more than fifteen years? Lyndsey Daniels doesn't have much time to walk down memory lane before she and Ian Fox find themselves thrown together to investigate the mysterious deaths of ten young men in the Canadian wilderness. How do the hearts of such seemingly normal, healthy men just...stop? With the hint of an evil spirit in the wind—and a whole lot of butterflies—there's no telling what Lyndsey and Ian are dealing with, including their own extensive baggage. Though sixteen years is a lot of life to live, there's one thing they can't deny: their attraction is as intense as ever. But is it just a spark that will burn itself out, or is it true love bringing them back together? When the force they're hunting turns its sights on them, the leap of faith required far exceeds the powers of either of them. But worrying about their future might be premature because one wrong move and they might not make it out alive. In Book One of the Butterfly Ops trilogy, Lyndsey and Ian reconnect fifteen years after seeing each other for what each thought was the last time. That the spark is still there is undeniable—but is it enough to get past the secrets and lies that tore them apart the first time around? With old tensions rearing their heads as new challenges arise, what at first seems to be a sure path back to trust and happiness is rockier than it seems. Note: this is Book One in a serial trilogy. Book Two will be released in Spring 2019; Book Three will be released in early Summer 2019. Books should be read in order.
Leader of the first tourist expedition into Yosemite in 1855, James Mason Hutchings became a tireless promoter of the valley-and of himself. Seeking to create an alternative to California's Gold Rush social chaos, Hutchings whetted the public enthusiasm for this unspoiled land by mass producing a lithograph of Yosemite Falls, while his Hutchings' California Magazine beat the drum for tourism. But because of his later legal imbroglios over the park, Hutchings was effectively written out of its history, and today he is largely viewed as an opportunist who made a career out of exploiting Yosemite. Now Jen Huntley removes the tarnish from Hutchings's image. She portrays him instead as a "connector" who brought artists to Yosemite and Yosemite to Americans, and uses his career as a lens through which to view the contests and debates surrounding the creation of Yosemite, and, by extension, America's emerging ethic of land conservation. Blending environmental and cultural history, she tracks Hutchings's professional trajectory amidst significant changes in nineteenth-century America, from technological advances in printing to the growth of tourism, from the birth of modern environmental movements to battles over public lands. Huntley uses Hutchings's legal battles with the government over ownership of land in the Yosemite Valley to analyze larger battles over public land management and national identity. She also explores the role of urban San Francisco in designating Yosemite a public park, shows how the Civil War transformed Yosemite from a regional icon to a national symbol of post-war redemption, and takes a closer look at Hutchings's relationship with John Muir. Making Yosemite sheds light on the role of power, class dynamics, and the late-century ideal of individualism in the shaping of modern America's sacred landscapes. Hutchings emerges here as a visionary communicator who cleverly tapped into midcentury Americans' attitudes toward spectacular scenery to create a sense of place-based identity in the American Far West. Huntley's revisionist approach rediscovers Hutchings as a key player in the histories of American media, tourism, and environmentalism, and suggests new terrain for scholars to consider in writing the histories of our national parks, conservation, and land policy.
This book covers the entire spectrum of health effects induced by chronic arsenic poisoning, which is prevalent in more than 30 countries due to the use of unclean underground water, a result of surface water pollution and shortage. This environmental health disaster has been considered more catastrophic than the Chernobyl nuclear plant explosion in the former Soviet Union and the Bhopal chemical plant explosion in India. All contributors to this review volume have done extensive research on arsenic poisoning and published excellent papers in internationally well-known journals. Health Hazards of Environmental Arsenic Poisoning includes reviews of the state-of-the-art literature and cutting-edge scientific evidence on arsenic-related health effects. It is also an important source of valuable information for health care workers, environmental scientists and epidemiologists, as well as public health practitioners.
This monograph is intended for an advanced undergraduate or graduate course as well as for researchers, who want a compilation of developments in this rapidly growing field of operations research. This is a sequel to our previous works: "Multiple Objective Decision Making--Methods and Applications: A state-of-the-Art Survey" (No.164 of the Lecture Notes); "Multiple Attribute Decision Making--Methods and Applications: A State-of-the-Art Survey" (No.186 of the Lecture Notes); and "Group Decision Making under Multiple Criteria--Methods and Applications" (No.281 of the Lecture Notes). In this monograph, the literature on methods of fuzzy Multiple Attribute Decision Making (MADM) has been reviewed thoroughly and critically, and classified systematically. This study provides readers with a capsule look into the existing methods, their characteristics, and applicability to the analysis of fuzzy MADM problems. The basic concepts and algorithms from the classical MADM methods have been used in the development of the fuzzy MADM methods. We give an overview of the classical MADM in Chapter II. Chapter III presents the basic concepts and mathematical operations of fuzzy set theory with simple numerical examples in a easy-to-read and easy-to-follow manner. Fuzzy MADM methods basically consist of two phases: (1) the aggregation of the performance scores with respect to all the attributes for each alternative, and (2) the rank ordering of the alternatives according to the aggregated scores.
Author Jen Kimberley was building a life for herself in Denver, Colorado after the death of her husband from lung cancer when she was accidentally diagnosed with leukemia. In My Cancer Survival Saga, she shares her personal story. Her narrative covers mistakes she made, things she learned the hard way, and people who helped her. It describes her first encounters with alternative cancer treatments such as IPT and hyperthermia; her changes in diet and lifestyle that removed toxins and increased oxygen levels; and the weight loss and weakness known as cachexia and coming out of it alive and strong despite conventional predictions. In sidebars, she offers helpful and educational information for readers who want to know more about treatment options other than chemotherapy, radiation, and surgery; and she teaches how best to work towards a cure rather than just remission. Along with one of Jen's entertaining poems, My Cancer Survival Saga also offers five sections on energy work to start clearing, validating, and protecting your own space. These include specific tools anyone can learn to use that remove stress and increase personal confidence.
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