This volume four of The Needs Assessment Kit provides a good overview of how to: analyze two distinct types of data; pull them together in a meaningful way; and to derive priorities from the collation of the information that has been generated by the needs assessment. What should result is a stronger foundation for needs-related decisions and one that will stand the scrutiny of involved and questioning audiences. áThis text offers guidance not absolute solutions to help needs assessment committees (NACs) and their facilitators work through the complexities of analysis and subsequent prioritization.
Frontiers in Computational Chemistry, originally published by Bentham and now distributed by Elsevier, presents the latest research findings and methods in the diverse field of computational chemistry, focusing on molecular modeling techniques used in drug discovery and the drug development process. This includes computer-aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. In Volume 2, the authors continue the compendium with nine additional perspectives in the application of computational methods towards drug design. This volume covers an array of subjects from modern hardware advances that accelerate new antibacterial peptide identification, electronic structure methods that explain how singlet oxygen damages DNA, to QSAR model validation, the application of DFT and DFRT methods on understanding the action of nitrogen mustards, the design of novel prodrugs using molecular mechanics and molecular orbital methods, computational simulations of lipid bilayers, high throughput screening methods, and more. - Brings together a wide range of research into a single collection to help researchers keep up with new methods - Uniquely focuses on computational chemistry approaches that can accelerate drug design - Makes a solid connection between experiment and computation, and the novel application of computational methods in the fields of biology, chemistry, biochemistry, physics, and biophysics
No single battalion was more feared during the Civil War than the 43rd Battalion of Virginia Cavalry. As one contemporary said, “They had…all the glamour of Robin Hood…all the courage and bravery of the ancient crusaders.” Better known as Mosby’s Rangers, they were an elite guerrilla unit that operated with stunning success in northern Virginia and Maryland from 1863 to the last days of the war. In this vivid account of the famous command of John Singleton Mosby, Jeffry D. Wert explores the personality of this iron-willed commander and brilliant tactician and gives us colorful profiles of the officers who served under him. Drawing on contemporary documents, including letters and diaries, this is the most complete and vivid account to date of the fighting unit that was so hated by General Ulysses S. Grant that he ordered any captured Ranger to be summarily executed without trial.
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