A thoughtfully researched, movingly presented dual–biography of two iconic American writers, each trying to find the ideal friend with whom they could share their journey through our imperfect world. Any biography that concentrates on either Henry David Thoreau or Ralph Waldo Emerson tends to diminish the other figure, but in Solid Seasons both men remain central and equal. Through several decades of writing, friendship remained a primary theme for them both. Collecting extracts from the letters and journals of both men, as well as words written about them by their contemporaries, Jeffrey S. Cramer beautifully illustrates the full nature of their twenty–five–year dialogue. Biographers like to point at the crisis in their friendship, focusing particularly on Thoreau's disappointment in Emerson—rarely on Emerson's own disappointment in Thoreau—and leaving it there, a friendship ruptured. But the solid seasons remained, as is evident when, in 1878, Anne Burrows Gilchrist, the English writer and friend of Whitman, visited Emerson. She wrote that his memory was failing "as to recent names and topics but as is usual in such cases all the mental impressions that were made when he was in full vigour remain clear and strong." As they chatted, Emerson called to his wife, Lidian, in the next room, "What was the name of my best friend?" "Henry Thoreau," she answered. "Oh, yes," Emerson repeated. "Henry Thoreau.
From Boron Trifluoride to Zinc, the 52 most widely used reagents in organic synthesis are described in this unique desktop reference for every organic chemist. The list of reagents contains classics such as N-Bromosuccinimide (NBS) and Trifluoromethanesulfonic Acid side by side with recently developed ones like Pinacolborane and Tetra-n-propylammonium Perruthenate (TPAP). For each reagent, a concise article provides a brief description of all important reactions for which the reagent is being used, including yields and reaction conditions, an overview of the physical properties of the reagent, its storage conditions, safe handling, laboratory synthesis and purification methods. Advantages and disadvantages of the reagent compared to alternative synthesis methods are also discussed. Reagents have been hand-picked from among the 5000 reagents contained in EROS, the Encyclopedia of Reagents for Organic Synthesis. Every organic chemist should be familiar with these key reagents that can make almost every reaction work.
Chronic obstructive pulmonary disease (COPD), which encompasses both chronic bronchitis and emphysema, is one of the most common respiratory conditions of adults in the developed world. Asthma and COPD: Basic Mechanisms and Clinical Management provides a unique, authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it is a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.* Highlights distinguishing features between asthma and COPD* Reviews benefits and limitations of current therapies* Summarises key information in two-colour artwork * Extensively referenced to primary literature
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