Inversion polymorphism in Drosophila has long served as a research subject for a variety of evolutionary studies and continues to be extremely important in understanding evolutionary principles today. Until now, no single volume has ever been assembled as a summary of this work. Drosophila Inversion Polymorphism provides background information, explores new and rigorous approaches to reconstructing phylogenetic relationships from inversion variation, and discusses inversion polymorphism in the six most studied species groups. Some chapters examine general principles and conclusions, some present detailed data sets (many of which have never before been published), and others offer detailed chromosome maps for identification. The book is a one-of-a-kind source of summary discussions and data ripe for analysis. Geneticists, evolutionary biologists, biologists, and all investigators researching inversion polymorphisms should consider Drosophila Inversion Polymorphism a "must-have" volume.
A clear, engaging writing style, hundreds of full-color images, and new information throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource for those who provide care for neonates with neurological conditions. World authority Dr. Joseph Volpe, along with Dr. Terrie E. Inder and other distinguished editors, continue the unparalleled clarity and guidance you've come to expect from the leading reference in the field – keeping you up to date with today's latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology. - Provides comprehensive coverage of neonatal neurology, solely written by the field's founding expert, Dr. Joseph Volpe - for a masterful, cohesive source of answers to any question that arises in your practice. - Focuses on clinical evaluation and management, while also examining the many scientific and technological advances that are revolutionizing neonatal neurology. - Organizes disease-focused chapters by affected body region for ease of reference. - Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs. - Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders. - Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women's Hospital, all of whom bring a wealth of insight to this classic text. - Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more. - Uses an improved organization to enhance navigation. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
In a pioneering work, Jeffrey Fear overturns the dominant understanding of German management as “backward” relative to the U.S. and uncovers an autonomous and sophisticated German managerial tradition. Beginning with founder August Thyssen—the Andrew Carnegie of Germany—Fear traces the evolution of management inside the Thyssen-Konzern and the Vereinigte Stahlwerke (United Steel Works) between 1871 and 1934. Fear focuses on the organization and internal dynamics of the company. He demonstrates that initiatives often flowed from middle managers, rather than from the top down. Shattering stereotypes of the overly bureaucratic and rigid German firm, Fear portrays a decentralized and flexible system that underscores the dynamic and entrepreneurial nature of German business. He fundamentally revises the scholarship on Alexander Gerschenkron and Germany’s Sonderweg, and critiques Max Weber’s concept of the corporation and capital accounting. He develops a loosely coupled relationship among enterprise strategy, organization, the structure of responsibility, and its accounting system, which links information, knowledge, and power inside the firm. This method of organizing control is central to understanding corporate governance. Original and provocative, this work will generate much debate among historians, organizational theorists, and management and accounting scholars.
Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students and professionals who are developing their knowledge of this important topic. Key topics covered include stem cells; morphogenesis and cellular signaling; the extracellular matrix; biocompatibility; scaffold design and fabrication; controlled release strategies; bioreactors; tissue engineering of skin, cartilage, bone and organ systems; and ethical issues. - Covers all the essentials from tissue homeostasis and biocompatibility to cardiovascular engineering and regulations - 22 chapters from internationally recognized authors, provide a comprehensive introduction for engineers and life scientists, including biomedical engineers, chemical and process engineers, materials scientists, biologists and medical students - Full colour throughout, with clear development of understanding through frequent examples, experimental approaches and the latest research and developments
A complex and captivating portrait of Mark Antony that offers a fresh perspective on the fall of the Roman Republic In his lifetime, Mark Antony was a famous man. Ally and avenger of Julius Caesar, rhetorical target of Cicero, lover of Cleopatra, and mortal enemy of Octavian (the future emperor Augustus), Antony played a leading role in the transformation of the Roman world. Ever since his and Cleopatra's demise at the hands of Octavian, he has remained famous, or infamous, a figure of recurring fascination. His life--variegated, passionate, sensual, bold, and tragic--inspires vigorous reactions. Nearly everyone has a view on Antony. For Cicero, he was a distasteful though talented man. Octavian fashioned him a dangerous failure, a Roman noble corrupted by his appetites and his lust for Cleopatra. Later historians adopted and adapted these themes, delivering their readers an Antony who was irresistibly depraved, startlingly brave, sometimes cunning, but almost always constitutionally incapable of choosing the right side of history. From these, especially Plutarch's compelling portrait, Shakespeare gave us the chivalrous and unstudied Antony of Antony and Cleopatra. A Noble Ruin, the fullest biography of Antony in English, assimilates the various, often competing, ancient sources to provide a strong and much-needed dose of realism to the caricature we have of this major historical figure. The book gives ample attention to the varied cultural circumstances in which Antony operated, including the social and moral expectations of his republican heritage, as well as the exceptional challenges posed by the convulsion of civil war. In furnishing a complex and captivating portrait of Anthony, A Noble Ruin allows readers to freshly assess his conduct, ambitions, and attainments, as well as the turbulent age in which he lived.
Revised and updated throughout, the 2nd Edition offers a concise, clinically focused, and practical approach to the diagnosis and management of the full range of issues in transfusion and blood banking. Jeffrey McCullough, MD, a national leader in the field, reviews the most common disorders involving red blood cells, white blood cells, and hemostasis, and examines each disease state with discussions of underlying pathophysiology, clinical features, up-to-date lab tests, and current management strategies. - Presents the practice-proven experience of a leader in the field of pathology and hematology. - Includes chapter summaries throughout for quick access to key guidance. - Offers complete, quick access guidance on the full range of topics in blood bank and transfusion—from blood collection and storage...to testing and transfusing blood components...to cellular engineering. - Discusses the latest developments, including HP growth factors and cellular engineering - Features a wealth of new illustrations and line drawings
High Speed Digital Design discusses the major factors to consider in designing a high speed digital system and how design concepts affect the functionality of the system as a whole. It will help you understand why signals act so differently on a high speed digital system, identify the various problems that may occur in the design, and research solutions to minimize their impact and address their root causes. The authors offer a strong foundation that will help you get high speed digital system designs right the first time. Taking a systems design approach, High Speed Digital Design offers a progression from fundamental to advanced concepts, starting with transmission line theory, covering core concepts as well as recent developments. It then covers the challenges of signal and power integrity, offers guidelines for channel modeling, and optimizing link circuits. Tying together concepts presented throughout the book, the authors present Intel processors and chipsets as real-world design examples. - Provides knowledge and guidance in the design of high speed digital circuits - Explores the latest developments in system design - Covers everything that encompasses a successful printed circuit board (PCB) product - Offers insight from Intel insiders about real-world high speed digital design
Wood Microbiology, Second Edition, presents the latest advances in wood decay and its prevention. Coverage includes classification of fungi and bacteria, factors affecting growth and survival, fungal metabolism, and wood chemistry. There are also chapters that focus on the anatomical aspects, chemical changes, and ultrastructural effects of wood decay. Additionally, this book discusses major issues associated with wood decay, detecting decay, and how to take protective action against it. This is a one-stop reference resource for wood scientists, wood processing and preserving professionals, foresters and forest pathologists, as well as students of forestry, and wood science and technology courses. It is authored by two leading experts with over 80 years of experience working with timber durability. - Provides updated taxonomy and classification of decay groups - Presents detailed descriptions of anatomical, chemical, and ultrastructural aspects of wood decay - Includes discussions on major issues associated with decay, how to detect decay and preventative measures
Explores the uses of Yiddish language in German literary and cultural texts 1781 until the late nineteenth century. This book explores the uses of Yiddish language in German literary and cultural texts from the onset of Jewish civil emancipation in the Germanies in 1781 until the late 19th century. Showing the various functions Yiddish assumedat this time, the study crosses traditional boundaries between literary and non-literary texts. It focuses on responses to Yiddish in genres of literature ranging from drama to language handbooks, from cultural criticism to the realist novel in order to address broader issues of literary representation and Jewish-German relations in the 18th and 19th centuries. Professor Grossman shows how the emergence of attitudes toward Jews and Yiddish is directly related to linguistic theories and cultural ideologies that bear a complex relationship to the changing social and political institutions of the time. Amidst the rise of national ideologies and modern anti-Semitism, the increasing consolidation of institutions, and the drive to cultural homogeneity in the 18th- and 19th-century German context, Yiddish functioned as an anarchic element that, in the view of its opponents, "threatened" to dissolve German nationalculture. Grossman locates the response to Yiddish in the context of historical events (the Hep Hep Riots of 1819, the Revolution of 1848) and institutional changes (Jewish legal emancipation, the promotion of Bildung as an educational and cultural ideal). In its methodology and its focus, this study seeks to show how the conflicted responses to the Yiddish language point to the problems that connected and frequently divided Jews and Germans as they soughtto re-invent themselves for a new and unsettling context.
The dream of mathematical modeling is of systems evolving in a continuous, deterministic, predictable way. Unfortunately continuity is lost whenever the `rules of the game' change, whether a change of behavioural regime, or a change of physical properties. From biological mitosis to seizures. From rattling machine parts to earthquakes. From individual decisions to economic crashes. Where discontinuities occur, determinacy is inevitably lost. Typically the physical laws of such change are poorly understood, and too ill-defined for standard mathematics. Discontinuities offer a way to make the bounds of scientific knowledge a part of the model, to analyse a system with detail and rigour, yet still leave room for uncertainty. This is done without recourse to stochastic modeling, instead retaining determinacy as far as possible, and focussing on the geometry of the many outcomes that become possible when it breaks down. In this book the foundations of `piecewise-smooth dynamics' theory are rejuvenated, given new life through the lens of modern nonlinear dynamics and asymptotics. Numerous examples and exercises lead the reader through from basic to advanced analytical methods, particularly new tools for studying stability and bifurcations. The book is aimed at scientists and engineers from any background with a basic grounding in calculus and linear algebra. It seeks to provide an invaluable resource for modeling discontinuous systems, but also to empower the reader to develop their own novel models and discover as yet unknown phenomena.
Each volume profiles about six to eight novelists, poets, playwrights, short story writers, and other creative and nonfiction writers who are currently active or who died after Dec. 31, 1999. A biographical and critical introduction to each author prefaces a collection of reprinted critical essays and reviews. A cumulative title index to the entire series is available separately (included in subscription).
Hamburger's singular discovery of a group of devotional drawings made by an anonymous nun . . . is here presented with magisterial learning, theoretical sophistication, and deep human sympathy."—V. A. Kolve, University of California, Los Angeles
Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician. Opioids and analgesics are members of a diverse group of drugs used to relieve pain. They are frequently used in combination with prescription and nonprescription pain relievers, and misuse is prevalent. Pain medicine specialists and physicians or surgeons will find this volume useful in prescribing the appropriate drugs for pain therapy and for preventing misuse of the medication. - The only drug guide that includes clinical case studies and expert analysis - UNIQUE! Features not only analgesics and anti-inflammatory drugs, but also all other drugs that act in an analgesic or anti-inflammatory manner - Most complete cross referencing of drug-drug interactions available - Latest content from the most highly regarded compilation of drug side effects: Side Effects of Drugs Annual serial
Provides current information on more than 5,000 legal topics. Includes completely revised articles covering important issues, biographies, definitions of legal terms and more. Covers such high-profile topics as the Americans with Disabilities Act, capital punishment, domestic violence, gay and lesbian rights, and physician-assisted suicide.
Make God's Word your everyday traveling companion. Thin and lightweight, Thomas Nelson's KJV Compact UltraSlim™ Bible boasts a complete and easy-to-read Bible that is ready to go when you are! A Bible you can be comfortable taking with you every day and everywhere you go, the Compact UltraSlim Bible is thin enough to tuck into your purse, briefcase, backpack, or glove compartment, yet large enough for easy readability. The Compact UltraSlim Bible is the perfect gift and ideal companion for today's Christian on the move. Features include: Presentation page Self-pronouncing text Words of Jesus in red Concordance Full-color maps Type size: 6 Part of the CLASSIC SERIES line of Thomas Nelson Bibles Compact UltraSlim Bibles sold to date: More than 135,000 The King James Version-The most successful Bible translation in history with billions of copies published Thomas Nelson Bibles is giving back through the God's Word in Action program. Donating a portion of profits to World Vision, we are helping to eradicate poverty and preventable deaths among children. Learn more and discover what you can do at www.seegodswordinaction.com.
The common fruitfly, Drosophila, is the most extensively studied of all organisms in genetical research. Thus, it would appear to be the best model for achieving new insights. Its use in evolutionary studies has resulted in an explosion of knowledge which has never before been gathered into a single volume. This book spans the full range of evolutionary studies - population genetics, ecology, ecological genetics, speciation, phylogenetics, genome evolution, molecular; evolution, and development. In covering these topics, highlights of empirical research are emphasized and are put into the context of major issues in evolution.
Now with full-color illustrations throughout, dozens of new review questions, and state-of-the-art coverage of this fast-changing area, Pediatric Gastrointestinal and Liver Disease, 6th Edition, remains the leading text in the field. You'll find definitive guidance on diagnosis and treatment from experienced editors Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay, as well as globally renowned contributors who share their knowledge and expertise on complex issues. - Features an enhanced art program with full-color anatomical figures, clinical photos, and other illustrations throughout the text. - Includes a new chapter on fecal transplantation (FCT), covering donor and recipient screening, preparation, delivery, follow-up, and safety considerations, as well as investigative uses for FCT for disorders such as IBD, IBS, and D-lactic acidosis. - Prepares you for certification and recertification with more than 400 board review-style questions, answers, and rationales – 30% new to this edition. - Includes detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes. - Contains numerous algorithms that provide quick and easy retrieval of diagnostic, screening, and treatment information. - Provides up-to-date information on indigenous flora and the gut microbiome and clinical correlations to treatment, as well as advancements in liver transplantation including split liver transplantation (SLT) and living donor liver transplantation (LDLT). - Details key procedures such as esophagogastroduodenoscopy and related techniques; colonoscopy and polypectomy; endoscopic retrograde cholangiopancreatography; capsule endoscopy and small bowel enteroscopy; gastrointestinal pathology; and more.
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