An integrated presentation of the basic science and clinical applications of anticancer agents Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications. After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating an ever-greater demand for safer, more effective anticancer agents. In response to that demand, the $100 billion cancer drug market continues to grow, with our increased understanding of cancer leading to new drugs being used clinically almost every year. Anticancer Therapeutics is divided into three sections. Section 1 is an introduction to cancer and therapeutics, and covers the etiology and cellular and molecular basis of cancer. In Section 2, the authors focus on the anticancer agents — their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. Section 3 focuses on specific cancers, explaining how and why the various agents discussed in Section 2 are used, both individually and in combination, to treat different cancers. Integrates aspects of basic science, including chemistry and pharmacology and clinical medicine in relation to cancer therapeutics Written by an author team comprising specialists in medicinal chemistry, pharmacology, and oncology Features full-color images throughout illustrating how drugs bind to cellular targets and exert their pharmacological effect Divided into three sections, covering the etiology and cellular and molecular basis of cancer, anticancer agents, and drug applications for different cancers. Providing the reader with an integrated understanding of all aspects of the science of anticancer agents, this is an ideal textbook for undergraduates studying medicine, nursing, medicinal chemistry, pharmacy, pharmacology and other allied heath / life sciences. It is also a valuable bench reference for pharmacists, medics, and pharmaceutical researchers working in both academia and industry.
Sharpen your critical thinking skills and prepare for real-world practice with clinical cases Build and enhance your knowledge of orthopaedic physical therapy with this accessible, case-filled resource. Each case includes a discussion of the health condition, examination, evaluation, diagnosis, plan of care and interventions, evidence-based practice recommendations, and references. NPTE-style review questions accompanying each case reinforce your learning. Featuring more than three dozen cases and new content, this updated edition of Physical Therapy Case Files: Orthopaedics is an ideal resource for coursework, NPTE preparation, and in the clinic. New: Coverage of blood flow restriction, dry needling, thoracic spine manipulation, and exercise for chronic low back pain 37 orthopaedic cases with National Physical Therapy Examination-style review questions to help users learn best practices in the context of patient care Evidence-based cases written by leading clinicians, researchers, and academics Includes evidence-based ratings for treatment plans Perfect for coursework use and NPTE preparation
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