The authors describe in detail the capture and use of design rationale in software engineering to improve the quality of software. Their book is the first comprehensive and unified treatment of rationale usage in software engineering. It provides a consistent conceptual framework and a unified terminology for comparing, contrasting and combining the myriad approaches to rationale in software engineering. It is both an excellent introductory text and a uniquely valuable reference.
The book makes a plea for systemic governance. It follows a practical approach including case studies and conceptual tools. Policy makers and managers need to work with rather than within theoretical and methodological frameworks. The closest we can get to truth is through compassionate dialogue that explores paradoxes and considers the rights and responsibilities of caretakers.
Nucleosides, Nucleotides, and Their Biological Applications contains the proceedings of the Fifth International Round Table on Nucleosides, Nucleotides, and Their Biological Applications held at Research Triangle Park, North Carolina on October 20-22, 1982. Contributors focus on the biological applications of nucleosides and nucleotides, along with advances in synthetic chemistry. Topic range from fast-moving biochemical subjects such as the 2',5'-oligoadenylates and their relationship to interferons; adenosine and adenine nucleotide receptors; and nucleosides with selective antiviral action. This volume is organized into 11 chapters and begins with an overview of nucleosides that are used as antiviral agents and their mechanism of action, including idoxuridine, vidarabine, and trifluridine. The discussion then shifts to the chemical and biological properties of nucleosides of purines and ring analogs; 2'-fluoroarabinosyl pyrimidines and purine-like C-nucleosides; and the potential of 2',5'-oligoadenylates as chemotherapeutic agents. The reader is also introduced to receptors for adenosine and adenine nucleotides; the function of pyrrolo[2,3-d]pyrimidine nucleosides in polynucleotides; and unusual nucleoside synthons and oligonucleotide synthesis. A chapter on the synthesis of versatile C-nucleoside precursors and certain C-nucleosides concludes the book. This book will be of value to chemists, biologists, and those with an interest in nucleosides and nucleotides.
The secure life of Rene Grenville crumbles when a drunk driver kills her mother. Consumed by her grief, shes skipping school and avoiding her friends. Home has become a battleground of daily fights with her dad, Steve. When a stalker turns her telephone into a tool of terror, she feels totally lost and alone. Follow Rene and her dad as they search for new life in the face of tragedy. Join Rene on her faith journey from a Mr. Fix-It God who has failed her, to a companion God who walks with her through lifes pain.
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