This balanced volume provides a broad and coherent overview of recent progress in membrane fusion research—highlighting an interdisciplinary treatment of the subject from the fields of biophysics, biochemistry, cell biology, virology, and biotechnology—in a single volume., Featuring easy-access sections on the general properties of membranes and applications of membrane fusion techniques, this valuable sourcebook outlines membrane structure, lipid polymorphism, and intermembrane forces ... covers membrane fusion in model systems ... presents the fusogenic properties of enveloped viruses ... discusses the fusion and flow of intracellular membranes and cell-cell fusion occurring during fertilization and myogenesis ... offers applications of membrane fusion techniques in cell-biological research and biotechnology ... and more. Supplying a comprehensive view of this exciting topic, Membrane Fusion is a working resource for molecular, cell, and membrane biologists; biophysicists; biochemists; virologists; biotechnologists; microbiologists; immunologists; physiologists; and graduate and medical school students in biophysics, biochemistry, physiology, virology, cell biology, and biotechnology.
Many books focus on individual differences and how those relate to traffic safety such as accident proneness, gender differences, age, alcohol, and the effects of drugs. Others focus on the safety effects regarding the vehicle such as airbags, anti-lock brakes, navigation systems, intelligent cruise control and other new gadgets coming to the vehicle. Even though these topics are undoubtedly important for traffic safety, this book takes a unique approach as it focuses solely on the road environment. Designing Safe Road Systems provides the background for those who want to know more about the effects of road design on driving behaviour. It uses a systems approach to allow a better understanding of why and in what circumstances drivers may commit errors. This understanding will ultimately lead to road systems that prevent (fatal) errors from occurring. The book contains an overview of the current models and theories about human performance and human behaviour in traffic that are relevant for all those involved in designing safe road systems. The central theme of this book is how design principles can reduce the probability of an error while driving. The authors demonstrate how knowledge of human factors helps a road authority to better understand how road users behave. They argue that in many cases the design of the environment can be further adjusted to human capabilities, and that safety should be considered a system property to be built into the road system.
`This book is a good comprehensive text and comes highly recommended to anyone currently involved in, looking to get involved in, or just interested in environmental management, environmental accounting and reporting′ - Pacific Accounting Review This is the long-awaited 2nd edition of the benchmark publication that helped shape the developing agenda of environmental accounting. This excellent new edition provides an overview of the subject ranging from environmental management to sustainability, and integrates the major advancements that have occurred since the first edition - in both research and practice. It introduces and explains environmental issues as they relate to accountants today. This new work also places an increased emphasis on the emerging research literature in the field and reveals a consciousness of the difficulties of developing an environmental agenda in business. It makes an excellent stand-alone text for lower level students, a firm base from which the advanced student or researcher can explore research and more complex issues, and a useful guide for practitioners seeking to understand and implement environmental practice.
This comprehensive reference is clearly destined to become the definitive anatomical basis for all molecular neuroscience research. The three volumes provide a complete overview and comparison of the structural organisation of all vertebrate groups, ranging from amphioxus and lamprey through fishes, amphibians and birds to mammals. This thus allows a systematic treatment of the concepts and methodology found in modern comparative neuroscience. Neuroscientists, comparative morphologists and anatomists will all benefit from: * 1,200 detailed and standardised neuroanatomical drawings * the illustrations were painstakingly hand-drawn by a team of graphic designers, specially commissioned by the authors, over a period of 25 years * functional correlations of vertebrate brains * concepts and methodology of modern comparative neuroscience * five full-colour posters giving an overview of the central nervous system of the vertebrates, ideal for mounting and display This monumental work is, and will remain, unique; the only source of such brilliant illustrations at both the macroscopic and microscopic levels.
The ongoing threat of pandemic influenza is very serious indeed as evidenced by recent articles within The Lancet and The Lancet Infectious Disease. This title provides the reader with authoritative and accessible information on the subject of influenza. Clearly written by key experts in the field and highly illustrated in full colour, the book provides an overview of influenza, its pathogenesis, epidemiology, the burden of disease and its health economics. Rapid Reference Influenza also summarises available information on the molecular biology of influenza and the emergence of new influenza viruses. Completely updated with the latest information on H5N1, the book aims to contribute to international efforts to emphasize the major burden of influenza and the need for better control. Expert information succinctly written for ease of use. Abundant use of bulleted lists and short tables, for quick access to comparative information. Presents evidence-based sources for practice when available, either through research or best-practice guidelines. Completely up-to-date in light of the H5N1 emergence and spread. Useful addresses and websites appendix provide additional resources for the physician. Updated epidemiology regarding H5N1. Revised discussion about the relevance of the potential impact of H5N1. Latest statistics from the World Health Organization. Update on 'pandemic preparedness' and related issues including new vaccine development. Includes an overview of current 'global thinking' about the possible pandemic including reports from the recent meeting between the WHO and the World Bank.
This book provides an overview of influenza, its pathogenesis, epidemiology, the burden of disease and its health economics. It also summarizes available information on the molecular biology of influenza and the emergence of new influenza viruses. It is written primarily for health care professionals, so they may understand the facts behind increased efforts to implement immunization policies recommended by health authorities in many countries. The book recognizes the key role of general practitioners in the prevention and treatment of influenza for the benefit of their patients and society. By publishing this book, the authors contribute to international efforts to emphasize the major burden of influenza and the need for better control. To increase awareness of the significant worldwide public health issue resulting from influenza infection, and therefore the importance of effective prevention strategies To emphasise the importance of early management of clinical symptoms, to reduce the morbidity and mortality of influenza, particularly in vulnerable groups such as the elderly or infirm To provide the busy healthcare professional with a pragmatic, easy-to-use guide, based on best practice and evidence-based medicine To provide a contemporary source of information for the user so that his/her management approach is up-to-date
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