The European Court of Justice has been celebrated as a central force in the creation and deepening of the EU internal market. Yet, it has also been criticized for engaging in judicial activism, restricting national regulatory autonomy, and taking away the powers of Member State institutions. In recent years, the Court appears to afford greater deference to domestic actors in free movement cases. Europe's Passive Virtues explores the scope of and reasons for this phenomenon. It enquires into the decision-making latitude given to the Member States through two doctrines: the margin of appreciation and decentralized judicial review. At the heart of the book lies an original empirical study of the European Court's free movement jurisprudence from 1974 to 2013. The analysis examines how frequently and under which circumstances the Court defers to national authorities. The results suggest that free movement law has substantially changed over the past four decades. The Court is leaving a growing range of decisions in the hands of national law-makers and judges, a trend that affects the level of scrutiny applied to Member State action, the division of powers between the European and national judiciary, and ultimately the nature of the internal market. The book argues that these new-found 'passive virtues' are linked to a series of broader political, constitutional, and institutional developments that have taken place in the EU.
For the first time, fixation, resin embedding and immunocytochemistry, the subjects of innumerable publications, have been organised into a comprehensive and coherent scheme showing how the various methodologies interrelate. Commercially available resins and their mode of use are described, and the book considers the advantages for cytochemistry and immunocytochemistry of matching tissue fixation to processing and resin embedding. On-section single and double immunolabelling methods are covered, using immunocolloidal gold and immunoperoxidase.
The second volume of the series Manuals in Biomedical Research, this book is aimed to be both a concise introduction to the diverse field of microscopy and a practical guide those who require the use of microscopic for methods in their research. It provides young as well as experienced scientists a state-of-the-art multidisciplinary overview of microscopic techniques, covering all the major microscopy fields in biomedical sciences and showing their application in evaluating samples ranging from molecules to cells and tissues.Microscopy has revolutionized our understanding of biological events. Within the last two decades, microscopic techniques have provided insights into the dynamics of biological processes that regulate such events. Biological discovery, to a large extent, depends on advances in imaging techniques and various microscopic techniques have emerged as central and indispensable tools in the biomedical sciences.The four authors bring with them extensive experiences spanning across disciplines such as Microbiology, Molecular and Cell Biology, Tissue Engineering, Biomedical and Regenerative Medicine and so forth, reinforcing the fact that microscopy has proven useful in countless investigations into the mysteries of life.
The result of more than twenty years' research, this seven-volume book lists over 23,000 people and 8,500 marriages, all related to each other by birth or marriage and grouped into families with the surnames Brandt, Cencia, Cressman, Dybdall, Froelich, Henry, Knutson, Kohn, Krenz, Marsh, Meilgaard, Newell, Panetti, Raub, Richardson, Serra, Tempera, Walters, Whirry, and Young. Other frequently-occurring surnames include: Greene, Bartlett, Eastman, Smith, Wright, Davis, Denison, Arnold, Brown, Johnson, Spencer, Crossmann, Colby, Knighten, Wilbur, Marsh, Parker, Olmstead, Bowman, Hawley, Curtis, Adams, Hollingsworth, Rowley, Millis, and Howell. A few records extend back as far as the tenth century in Europe. The earliest recorded arrival in the New World was in 1626 with many more arrivals in the 1630s and 1640s. Until recent decades, the family has lived entirely north of the Mason-Dixon Line.
Studebaker and the Railroads is a history of the Studebaker Corporation and of the railroads that served it in and around the city of South Bend, Indiana. Both Studebaker and the railroads of northern Indiana have extensive and dramatic histories and there are many connections between the two. Studebaker lovers and railfans will equally enjoy the stories and facts reported.Divided into two volumes, Studebaker and the Railroads comprises over four hundred fifty pages and contains over three hundred fifty photographs, drawings, maps and diagrams.Volume 1 covers the Studebaker and the steam railroads that once decorated South Bend. Volume 2 covers the extensive electric railroad history of the area and includes a history of Studebaker's private in-plant railroad, the Chicago & South Bend, together with additional topics linking Studebaker and railroading. Both volumes feature detailed indexes. Volume 2 includes an extensive bibliography, numerous maps, and corporate history charts.
This volume introduces a summary of all the techniques used to estimate pH reliably. Emphasis is placed on the techniques that provide the most reliable and detailed data. The role of cell pH is explained with special emphasis on enzymology and membrane transport and bioenergetics. This book was written especially for molecular biologists, biochemists and biophysicists.
This book explores the extent to which a transformation of public employment regimes has taken place in four Western countries, and the factors influencing the pathways of reform. It demonstrates how public employment regimes have unravelled in different domains of public service, contesting the idea that the state remains a 'model' employer.
This outstanding work is a manual that enables one to identify pupae, or empty pupal skins, of about two thirds (some 2,600 species) of the Central European Lepidoptera. The text part of about 560 pages comprises a short introduction, identification keys, and species-for species accounts including succinct descriptions of pupal morphology as well as information about habitats, life-style and food plants. Lepidoptera Pupae of Central Europe should be useful for anyone with a primary interest in Central European Lepidoptera. It will also be indispensable for population ecologists studying predators and parasites of Lepidoptera, for soil biologists (since so many Lepidoptera pupate in/on the soil), and for applied entomologists in need of identifying lepidopteran pests without rearing the adults. All families are well covered except for the Nepticulidae and Coleophoridae, for which much basic research on pupal stucture still remains to be done (and whose immatures are usually identifiable from mine architecture/case structure anyway) and a few of the smallest families. The print edition is available as a set of two volumes (9788788757477).
The Power of Design offers an introduction and a practical guide to product innovation, integrating the key topics that are necessary for the design of sustainable and energy-efficient products using sustainable energy technologies. Product innovation in sustainable energy technologies is an interdisciplinary field. In response to its growing importance and the need for an integrated view on the development of solutions, this text addresses the functional principles of various energy technologies next to the latest design processes and innovation methods. From the perspective of product applications, the book provides clear explanations of technologies that are significant for product integration, such as batteries, photovoltaic solar energy, fuel cells, small wind turbines, human power, energy saving lighting, thermal energy technologies in buildings, and piezoelectric energy conversions. The design processes and innovation methods presented in this book include various approaches ranging from technical, societal and creative methods that can be applied in different stages of the design process. Other features include: a methodological approach, enabling readers to easily apply the theory to their research projects and to the actual design of sustainable products with energy technologies discussion on interaction design and smart grid interventions colour photographs that illustrate the final products numerous case studies of product development projects and concepts in practice, enabling readers to understand and design energy-efficient products in several different markets a companion website containing useful information about the cases and an additional design cases with sustainable energy technologies The Power of Design provides a comprehensive and visually-appealing opening into the subject for third and fourth year students, postgraduates, and professionals in the areas of energy, environment, product design and engineering
Nicolaas van Wijk (1880-1941) was the founder of Slavic studies in the Netherlands and one of the greatest Slavists in general. This book describes for the first time how a scholar of the Dutch language, whose etymological dictionary of the Dutch language is still considered the best of its kind, was appointed in 1913 to the newly created Chair in Slavic languages at Leiden University and built up a tremendous reputation for himself in Eastern Europe. Van Wijk’s relations with his famous teacher, the linguist C.C. Uhlenbeck, are followed attentively, as is his postgraduate apprenticeship in Leipzig (1902-1903), where he followed August Leskien’s lectures in Slavic studies. Attention is also paid to the various aspects of Van Wijk’s enormous oeuvre covering the whole field of Slavic studies and of phonology, of which he was one of the pioneers. Van Wijk did not, however, follow the lines approved for the social conduct of a Leiden professor and was at one time suspected by the police of communist activities. His commitment to materially helping all he could from an Eastern Europe torn apart by the First World War and its aftermath was exceptional. His fascination with all things Russian is a background theme that played throughout his life and even at his death: son of a Dutch Reformed minister, the bachelor Van Wijk was buried in a grave surmounted by a Russian Orthodox cross beside his Russian foster son, who died young. This book is of interest to Slavists, linguists and cultural historians.
The general concept of information is here, for the first time, defined mathematically by adding one single axiom to the probability theory. This Mathematical Theory of Information is explored in fourteen chapters: 1. Information can be measured in different units, in anything from bits to dollars. We will here argue that any measure is acceptable if it does not violate the Law of Diminishing Information. This law is supported by two independent arguments: one derived from the Bar-Hillel ideal receiver, the other is based on Shannon's noisy channel. The entropy in the 'classical information theory' is one of the measures conforming to the Law of Diminishing Information, but it has, however, properties such as being symmetric, which makes it unsuitable for some applications. The measure reliability is found to be a universal information measure. 2. For discrete and finite signals, the Law of Diminishing Information is defined mathematically, using probability theory and matrix algebra. 3. The Law of Diminishing Information is used as an axiom to derive essential properties of information. Byron's law: there is more information in a lie than in gibberish. Preservation: no information is lost in a reversible channel. Etc. The Mathematical Theory of Information supports colligation, i. e. the property to bind facts together making 'two plus two greater than four'. Colligation is a must when the information carries knowledge, or is a base for decisions. In such cases, reliability is always a useful information measure. Entropy does not allow colligation.
Fascia in Sport and Movement, Second edition is a multi-author book with contributions from 51 leading teachers and practitioners across the entire spectrum of bodywork and movement professions. It provides professionals from all bodywork and movement specialisms with the most up-to-date information they need for success in teaching, training, coaching, strengthening, tackling injury, reducing pain, and improving mobility. The new edition has 21 new chapters, and chapters from the first edition have been updated with new research. This book is an essential resource for all bodywork professionals - sports coaches, fitness trainers, yoga teachers, Pilates instructors, dance teachers and manual therapists. It explains and demonstrates how an understanding of the structure and function of fascia can inform and improve your clinical practice. The book's unique strength lies in the breadth of its coverage, the expertise of its authorship and the currency of its research and practice base.
Covering the major topics of evolutionary game theory, Game-Theoretical Models in Biology, Second Edition presents both abstract and practical mathematical models of real biological situations. It discusses the static aspects of game theory in a mathematically rigorous way that is appealing to mathematicians. In addition, the authors explore many applications of game theory to biology, making the text useful to biologists as well. The book describes a wide range of topics in evolutionary games, including matrix games, replicator dynamics, the hawk-dove game, and the prisoner’s dilemma. It covers the evolutionarily stable strategy, a key concept in biological games, and offers in-depth details of the mathematical models. Most chapters illustrate how to use Python to solve various games. Important biological phenomena, such as the sex ratio of so many species being close to a half, the evolution of cooperative behaviour, and the existence of adornments (for example, the peacock’s tail), have been explained using ideas underpinned by game theoretical modelling. Suitable for readers studying and working at the interface of mathematics and the life sciences, this book shows how evolutionary game theory is used in the modelling of these diverse biological phenomena. In this thoroughly revised new edition, the authors have added three new chapters on the evolution of structured populations, biological signalling games, and a topical new chapter on evolutionary models of cancer. There are also new sections on games with time constraints that convert simple games to potentially complex nonlinear ones; new models on extortion strategies for the Iterated Prisoner’s Dilemma and on social dilemmas; and on evolutionary models of vaccination, a timely section given the current Covid pandemic. Features Presents a wide range of biological applications of game theory. Suitable for researchers and professionals in mathematical biology and the life sciences, and as a text for postgraduate courses in mathematical biology. Provides numerous examples, exercises, and Python code.
This book is the first systematic treatment of measures on projection lattices of von Neumann algebras. It presents significant recent results in this field. One part is inspired by the Generalized Gleason Theorem on extending measures on the projection lattices of von Neumann algebras to linear functionals. Applications of this principle to various problems in quantum physics are considered (hidden variable problem, Wigner type theorems, decoherence functional, etc.). Another part of the monograph deals with a fascinating interplay of algebraic properties of the projection lattice with the continuity of measures (the analysis of Jauch-Piron states, independence conditions in quantum field theory, etc.). These results have no direct analogy in the standard measure and probability theory. On the theoretical physics side, they are instrumental in recovering technical assumptions of the axiomatics of quantum theories only by considering algebraic properties of finitely additive measures (states) on quantum propositions.
In his Histories, Herodotus of Halicarnassus gave an account of Xerxes’ invasion of Greece (480 BCE). Among the information in this work features a rich topography of the places visited by the army, as well as of the battlefields. Apparently there existed a certain demand among the Greeks to behold the exact places where they believed that the Greeks had fallen, gods had appeared, or Xerxes had watched over his men. This book argues that Herodotus’ topography, long taken at face value as if it provided unambiguous access to the historical sites of the war, may partly be a product of Greek imagination in the approximately fifty years between the Xerxes’ invasion and its publication, with the landscape functioning as a catalyst. This innovative approach leads to a new understanding of the topography of the invasion, and of the ways in which Greeks in the late fifth century BCE understood the world around them. It also prompts new suggestions about the real-world locations of various places mentioned in Herodotus’ text.
This balanced volume provides a broad and coherent overview of recent progress in membrane fusion research—highlighting an interdisciplinary treatment of the subject from the fields of biophysics, biochemistry, cell biology, virology, and biotechnology—in a single volume., Featuring easy-access sections on the general properties of membranes and applications of membrane fusion techniques, this valuable sourcebook outlines membrane structure, lipid polymorphism, and intermembrane forces ... covers membrane fusion in model systems ... presents the fusogenic properties of enveloped viruses ... discusses the fusion and flow of intracellular membranes and cell-cell fusion occurring during fertilization and myogenesis ... offers applications of membrane fusion techniques in cell-biological research and biotechnology ... and more. Supplying a comprehensive view of this exciting topic, Membrane Fusion is a working resource for molecular, cell, and membrane biologists; biophysicists; biochemists; virologists; biotechnologists; microbiologists; immunologists; physiologists; and graduate and medical school students in biophysics, biochemistry, physiology, virology, cell biology, and biotechnology.
European Union Law and Private International Law both attempt to resolve a conflict of laws. There is however a certain tension between the two disciplines. The present book proposes suggestions to enhance their mutual understanding.
This is a cultural and intellectual biography of a neglected but important figure, Thomas Morgan (1671/2–1743). Educated at Bridgewater Academy, he was active as Presbyterian preacher, medical practitioner, and one of the first who called himself a Christian Deist. Morgan was not only a harbinger of the disparagement of the Old Testament, but also a prolific pamphleteer about things religious, and a publisher of medical books. He received praise for his medical work, but a negative press for his theological visions, and he ended as a forgotten figure in history; this book restores an overlooked writer to his due place in history. It is the first modern biography of Morgan and its readership comprises historians of deism, the enlightenment, the eighteenth century, theology and the church, Presbyterianism, and medical history.
Jan-Hendrik Sewing makes a significant contribution to opening the black box of current divestiture decision-making. He uses detailed case studies, including numerous interviews with corporate executives and experts from management consulting, private equity, and investment banking. The author develops a conceptual framework to identify remedies to behavioral pathologies and their origins. The study highlights multiple techniques for pursuing divestitures proactively and formulates best-practice recommendations.
Completely updated edition, written by a close-knit author team Presents a unique approach to stroke - integrated clinical management that weaves together causation, presentation, diagnosis, management and rehabilitation Includes increased coverage of the statins due to clearer evidence of their effectiveness in preventing stroke Features important new evidence on the preventive effect of lowering blood pressure Contains a completely revised section on imaging Covers new advances in interventional radiology
In the twenty-first century technology has become global, and firms compete using knowledge and capital. The ‘traditional firm’ has a need for innovation and depends on efficient knowledge management to improve productivity. This book examines five firms that produce the same commodity, white chicken meat, in different parts of the world and under very different conditions. It brings to bear the expertise and international perspectives of the author team, utilizing theoretical discussions and case studies to address the question: How do local firms use knowledge to compete in an increasingly globalized world? This book will be of interest to any postgraduate student, researcher or policymaker hoping to achieve a firmer grasp of innovation and knowledge management: a recurring and highly pertinent theme in contemporary economics.
Combinatorics and Algebraic Geometry have enjoyed a fruitful interplay since the nineteenth century. Classical interactions include invariant theory, theta functions and enumerative geometry. The aim of this volume is to introduce recent developments in combinatorial algebraic geometry and to approach algebraic geometry with a view towards applications, such as tensor calculus and algebraic statistics. A common theme is the study of algebraic varieties endowed with a rich combinatorial structure. Relevant techniques include polyhedral geometry, free resolutions, multilinear algebra, projective duality and compactifications.
Jan Piek provides guidance to help students understand infant motor development from a variety of disciplines and perspectives. She outlines current theory and research on the topic.
Jan Brinckmann analyzes how competencies of founders of new technology-based firms affect the development of their ventures. The research is grounded in competence-related literature and combines insights from entrepreneurship and management research.
The purpose of this unique book is to outline the core of game science by presenting principles underlying the design and use of games and simulations. Game science covers three levels of discourse: the philosophy of science level, the science level, and the application or practical level. The framework presented will help to grasp the interplay between forms of knowledge and knowledge content, interplay that evolves through the action of the players.
Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. - Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion - Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning - New edition contains material on regulatory authorities and commercial considerations in tissue engineering
The result of more than twenty years' research, this seven-volume book lists over 23,000 people and 8,500 marriages, all related to each other by birth or marriage and grouped into families with the surnames Brandt, Cencia, Cressman, Dybdall, Froelich, Henry, Knutson, Kohn, Krenz, Marsh, Meilgaard, Newell, Panetti, Raub, Richardson, Serra, Tempera, Walters, Whirry, and Young. Other frequently-occurring surnames include: Greene, Bartlett, Eastman, Smith, Wright, Davis, Denison, Arnold, Brown, Johnson, Spencer, Crossmann, Colby, Knighten, Wilbur, Marsh, Parker, Olmstead, Bowman, Hawley, Curtis, Adams, Hollingsworth, Rowley, Millis, and Howell. A few records extend back as far as the tenth century in Europe. The earliest recorded arrival in the New World was in 1626 with many more arrivals in the 1630s and 1640s. Until recent decades, the family has lived entirely north of the Mason-Dixon Line.
This book provides an innovative approach to sustainable development, one based on insights gleaned from the Industrial Revolution to the present, and which highlights the importance of aligning economic interests with sustainable development considerations. It investigates how a broad-based systematic approach can be used to develop societies sustainably by integrating environmental issues into the capitalist system without value-laden approaches, which produce little more than politics and inaction as we are witnessing today. The proposed approach focuses on realigning the financial markets to providing capital at reasonable cost to fuel innovation towards sustainable development across the entire economy. This requires government policies that level the playing field and also intervene strategically in cases where the playing field is weak or missing . Intended for researchers, policy-makers and graduate students, the book will also benefit non-governmental organizations, economists and the general public.
Mammals of Africa (MoA) is a series of six volumes which describes, in detail, every currently recognized species of African land mammal. This is the first time that such extensive coverage has ever been attempted, and the volumes incorporate the very latest information and detailed discussion of the morphology, distribution, biology and evolution (including reference to fossil and molecular data) of Africa's mammals. With 1,160 species and 16 orders, Africa has the greatest diversity and abundance of mammals in the world. The reasons for this and the mechanisms behind their evolution are given special attention in the series. Each volume follows the same format, with detailed profiles of every species and higher taxa. The series includes some 660 colour illustrations by Jonathan Kingdon and his many drawings highlight details of morphology and behaviour of the species concerned. Diagrams, schematic details and line drawings of skulls and jaws are by Jonathan Kingdon and Meredith Happold. Every species also includes a detailed distribution map. Extensive references alert readers to more detailed information. Volume I: Introductory Chapters and Afrotheria (352 pages) Volume II: Primates (560 pages) Volume III: Rodents, Hares and Rabbits (784 pages) Volume IV: Hedgehogs, Shrews and Bats (800 pages) Volume V: Carnivores, Pangolins, Equids and Rhinoceroses (560 pages) Volume VI: Pigs, Hippopotamuses, Chevrotain, Giraffes, Deer and Bovids (704 pages)
Drawn after nature presents a vivid and complete picture of a unique historical collection of botanical watercolours. Botanists, art lovers, historians as well as the general public will enjoy this publication of the watercolours, their annotations and their history, but above all their supreme beauty and display of craftsmanship. For over 300 years, the Preußische Staatsbibliothek in Berlin held a most remarkable collection of botanical watercolours. They were catalogued as part of the library’s illustrated manuscripts, or Libri Picturati. These magnificent works of art, rich in colour and detail, were made in the second half of the 16th century in the southern part of the Low Countries. In the 1970s the complete set of watercolours had been rediscovered and sparked the interest of historians, art historians and botanists alike. Together they set out to unravel the many secrets still held by the Libri Picturati’s watercolours: who had collected them, and why? A team of pre-eminent European scientists worked together on these and other intriguing questions surrounding the collection. They unveiled the important role played by the famous Dutch botanist Carolus Clusius, who later founded the University of Leiden’s Botanical Gardens. Drawn after nature contains accessible and informative chapters on the collection’s history, but most importantly: it brings together all of the original 1429 watercolours and sketches, for the first time in one volume, accompanied by their original annotations.
The quality of life for millions of people all over the globe has been improved by the work of diligent biologists and doctors working in the many branches of life science. An improved knowledge of how the body functions at the genetic, cellular, physiological and behavioural levels and a greater understanding of disease and pharmacology have resulted in a reduction in human suffering. The way is being paved for the effective treatment of some of the greatest health problems of the late twentieth century ? cancer, AIDS and diseases caused by parasites.These two volumes are collections of the Nobel Lectures delivered by the laureates, together with their biographies, portraits and the presentation speeches for the periods 1971 ? 1980 and 1981 ? 1990 respectively. Each Nobel Lecture is based on the work for which the laureate was awarded the prize. New biographical data of the laureate are also included. These volumes of inspiring lectures by outstanding scientists should be on the bookshelf of every keen student, teacher and professor of biological and medical sciences as well as of those in related fields.During the period 1971 ? 1980 important areas of research being recognized were as diverse as hormone action and radioimmunoassays, infectious diseases, molecular genetics, immunology, computerized tomography and social behaviour. The laureates according to the specific year are: (1971) E W SUTHERLAND JR ? for his discoveries concerning the mechanisms of the action of hormones; (1972) G M EDELMAN & R R PORTER ? for their discoveries concerning the chemical structure of antibodies; (1973) K VON FRISCH, K LORENZ & N TINBERGEN ? for their discoveries concerning organization and elicitation of individual and social behaviour patterns; (1974) A CLAUDE, C DE DUVE & G E PALADE ? for their discoveries concerning the structural and functional organization of the cell; (1975) D BALTIMORE, R DULBECCO & H M TEMIN ? for their discoveries concerning the interaction between tumour viruses and genetic material of the cell; (1976) B S BLUMBERG & D C GAJDUSEK ? for their discoveries concerning new mechanisms for the origin and dissemination of infectious diseases; (1977) R GUILLEMIN & A V SCHALLY ? for their discoveries concerning the peptide hormone production of the brain; and R S YALOW ? for the development of radioimmunoassays of peptide hormones; (1978) W ARBER, D NATHANS & H O SMITH ? for the discovery of restriction enzymes and their application to problems of molecular genetics; (1979) A M CORMACK & G N HOUNSFIELD ? for the development of computer assisted tomography; (1980) B BENACERRAF, J DAUSSET & G D SNELL ? for their discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions.
There may still be time for a despondent, mysterious old house with tiny pineapples carved on its eaves to fulfill the dream of one of its owners over seventy years ago. But in order for that to happen, two retired ladies, one black and one white, must unravel the mystery that surrounds both the house and the children who have come to believe it belongs to them. It's these children, living in the apartment complex across from Blessing Path, that most need the puzzle solved because the "For Sale" sign just placed amid the weeds in the front yard seems ominous to them. The clues include old newspaper clippings, a policeman's chance meeting with a soft-spoken genteel visitor, love letters during World War II, and a mason jar, recently excavated from the backyard that is filled with exquisite patterned shells of the sea, long protected by its rusty cap. Together, these pieces of information draw the ladies from the heart of Texas to the sparkling South Carolina coast and deep into the culture of Charleston and its Gullah heritage. Sweet Grass Memories was built on Texas soil, but if you cross her threshold and wait quietly for a few moments, you might just catch a whiff of pluff mud and taste the saltiness of sea air.
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