Dr. Hatanaka's exhaustive research and analysis have resulted in a book that should be an essential tool for those professionals who are assisting our soldiers having difficulties adjusting to life after the stress of service in a war zone. Likewise, soldiers, their families, and their friends experiencing difficulties understanding their own feelings and frustrations would benefit from taking the time to read this practical toolbox of ideas." --Lewis MacKenzie, CM, OOnt, MSC and Bar, CD Major-General (Ret'd) Jan Hatanaka, PhD, is the founder of Grief Reconciliation International Inc. Her pragmatic approach to grief and reconciliation is informed by her personal experience; her extensive academic research on the universality of grief and loss; and her in-depth discussions with hundreds of individuals willing to recount their personal stories when faced with significant grief. She has a Bachelor of Science degree in Nursing from the University of Ottawa, a Master's degree in Education and Counselling Psychology from the University of Toronto, and a PhD in Theology from the University of Wales.
Now available in paperback -- Jan Hatanaka's powerful, life-enhancing book on how six people, encountering significant adversity, made a conscious choice to work to build a life of meaning. Using six stories from her casebook as a therapist, Hatanaka explores and illustrates the complex relationships that exist between death and grief and the path that can lead to reconciling that grief. Included in her stories is her own heart-wrenching and dramatic experience following a major health crisis. Hatanaka draws on her personal, clinical, and academic experience as she takes the reader through the Grief Reconciliation Process, describing the actual steps taken by people who manage to build a life of meaning in the face of significant adversity. The Choice is brilliant in its simple, gentle, and profound exploration of the reality of suffering as part of the human experience. It exposes the hope that can be hidden in affliction. The Choice will be of great help to those currently in the grips of personal adversity; the loved ones of those who are suffering; and health-care professionals, including medical practitioners, counsellors, therapists, and spiritual advisors. Jan Hatanaka, the founder of Grief Reconciliation International Inc., holds positions at York University, Toronto, in the Department of Nursing, the Religious Studies program, and the York Institute for Health Research. She has a B.Sc. in Nursing from the University of Ottawa, a Master's degree in Education and Counselling Psychology from the University of Toronto, and a Ph.D. in Theology from the University of Wales. Dr. Hatanaka's approach to grief and reconciliation is informed by her personal experience; her extensive academic research on the universality of grief and loss; and her in-depth discussions with hundreds of individuals willing to recount their personal stories.
Dr. Hatanaka's exhaustive research and analysis have resulted in a book that should be an essential tool for those professionals who are assisting our soldiers having difficulties adjusting to life after the stress of service in a war zone. Likewise, soldiers, their families, and their friends experiencing difficulties understanding their own feelings and frustrations would benefit from taking the time to read this practical toolbox of ideas." --Lewis MacKenzie, CM, OOnt, MSC and Bar, CD Major-General (Ret'd) Jan Hatanaka, PhD, is the founder of Grief Reconciliation International Inc. Her pragmatic approach to grief and reconciliation is informed by her personal experience; her extensive academic research on the universality of grief and loss; and her in-depth discussions with hundreds of individuals willing to recount their personal stories when faced with significant grief. She has a Bachelor of Science degree in Nursing from the University of Ottawa, a Master's degree in Education and Counselling Psychology from the University of Toronto, and a PhD in Theology from the University of Wales.
Now available in paperback -- Jan Hatanaka's powerful, life-enhancing book on how six people, encountering significant adversity, made a conscious choice to work to build a life of meaning. Using six stories from her casebook as a therapist, Hatanaka explores and illustrates the complex relationships that exist between death and grief and the path that can lead to reconciling that grief. Included in her stories is her own heart-wrenching and dramatic experience following a major health crisis. Hatanaka draws on her personal, clinical, and academic experience as she takes the reader through the Grief Reconciliation Process, describing the actual steps taken by people who manage to build a life of meaning in the face of significant adversity. The Choice is brilliant in its simple, gentle, and profound exploration of the reality of suffering as part of the human experience. It exposes the hope that can be hidden in affliction. The Choice will be of great help to those currently in the grips of personal adversity; the loved ones of those who are suffering; and health-care professionals, including medical practitioners, counsellors, therapists, and spiritual advisors. Jan Hatanaka, the founder of Grief Reconciliation International Inc., holds positions at York University, Toronto, in the Department of Nursing, the Religious Studies program, and the York Institute for Health Research. She has a B.Sc. in Nursing from the University of Ottawa, a Master's degree in Education and Counselling Psychology from the University of Toronto, and a Ph.D. in Theology from the University of Wales. Dr. Hatanaka's approach to grief and reconciliation is informed by her personal experience; her extensive academic research on the universality of grief and loss; and her in-depth discussions with hundreds of individuals willing to recount their personal stories.
A. Definitions of Transformation in vitro When normal tissues or organs are explanted to conditions favoring the growth of cells as individual units ("cell culture"), the original cell population undergoes a large variety of modifications. Only a minority of the cells will thrive and multiply and within a rather short period of time, the complex composition of the original explant is replaced by a much simplified one of only a few recogniz ably different cell types. With most organs fibroblast-like cells survive longest and outgrow other types. This is then a stable state of affairs for many gener ations. This treatise will not discuss whether this simplification and stabilization represents selection of certain pre-existing cell types or a modification of cells into only a few recognizably different categories; for an excellent review see HARRIS. (1964). Table 1. Terminology Employed to Describe Transformations in vitro Type of transformation Essential features Irregular growth Lack of contact inhibition of cell membrane movement ("ruffled membranes") between juxtaposed cells Unrestrained growth Deficient inhibition of the cell cycle (mitosis) in a crowded culture Infinite growth Capacity of cells to undergo an infinite number of di visions (formation of established cell lines) Cells may depart from this typical behavior in numerous ways involving for instance cellular morphology, immunology, chromosomes or metabolism. Such changes have, sometimes rather vaguely, been called "transformations". This is unprecise and the term "transformation" will here be used exclusively to indicate disturbances in cell growth related to neoplasia.
The award-winning Rough Guide to Japan is the definitive guide to this fascinating country with its stunning landscapes, dynamic pop culture, world-class dining and rich history. It will guide you with reliable information and a clearly explained background on everything from Japan's history, religions, arts, movies and music to the country's pressing environmental issues. Whether you're looking for great places to eat and drink or the most exciting places to party and the newest accommodation, you'll find the solution. Plus, all the major and many off-the-beaten-track sights are covered, including tropical dives in Okinawa, mountain traverses across the Japanese Alps and contemporary art exhibits on islands in the Inland Sea. Accurate maps and comprehensive practical information help you get under the skin of this dynamic country, whilst stunning photography makes The Rough Guide to Japan your ultimate travelling companion. Now available in epub format. Make the most of your trip with The Rough Guide to Japan.
Statistical Methods for Long Term Memory Processes covers the diverse statistical methods and applications for data with long-range dependence. Presenting material that previously appeared only in journals, the author provides a concise and effective overview of probabilistic foundations, statistical methods, and applications. The material emphasizes basic principles and practical applications and provides an integrated perspective of both theory and practice. This book explores data sets from a wide range of disciplines, such as hydrology, climatology, telecommunications engineering, and high-precision physical measurement. The data sets are conveniently compiled in the index, and this allows readers to view statistical approaches in a practical context. Statistical Methods for Long Term Memory Processes also supplies S-PLUS programs for the major methods discussed. This feature allows the practitioner to apply long memory processes in daily data analysis. For newcomers to the area, the first three chapters provide the basic knowledge necessary for understanding the remainder of the material. To promote selective reading, the author presents the chapters independently. Combining essential methodologies with real-life applications, this outstanding volume is and indispensable reference for statisticians and scientists who analyze data with long-range dependence.
Carbohydrates offer a ready source of enantiomerically pure starting materials. They have been used for the imaginative synthesis of a wide range of compounds, and have been found to be effective chiral auxiliaries which enable the introduction of a range of functionalities in a highly enantioselective manner. In a subject dominated by volumes at research and professional level, this book provides a broad understanding of the use of carbohydrates in organic synthesis, at postgraduate student level. Emphasis is placed on retrosynthetic analysis, with discussion of why a particular synthetic route has been chosen, and mechanistic explanations are provided for key and novel reactions. Wherever possible, the authors highlight points of general significance to organic synthesis. Selected experimental conditions and reaction details are incorporated to ensure that information can be utilised in research. The book is extensively referenced and so provides a convenient point of entry to the primary literature.
Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers.
Power Aware Design Methodologies was conceived as an effort to bring all aspects of power-aware design methodologies together in a single document. It covers several layers of the design hierarchy from technology, circuit logic, and architectural levels up to the system layer. It includes discussion of techniques and methodologies for improving the power efficiency of CMOS circuits (digital and analog), systems on chip, microelectronic systems, wirelessly networked systems of computational nodes and so on. In addition to providing an in-depth analysis of the sources of power dissipation in VLSI circuits and systems and the technology and design trends, this book provides a myriad of state-of-the-art approaches to power optimization and control. The different chapters of Power Aware Design Methodologies have been written by leading researchers and experts in their respective areas. Contributions are from both academia and industry. The contributors have reported the various technologies, methodologies, and techniques in such a way that they are understandable and useful.
Immunodermatology is a field covering the majority of skin diseases, including the most prevalent onesin the general population. The Second Edition of Skin Immune System (SIS) discusses immune-mediated skin diseases and disease groups in which the SIS plays a role. It covers major findings in immunophysiology and immunopathology that have occurred since the introduction of the First Edition in 1990. As the subtitle indicates, the Second Edition adds a new emphasis on cutaneous immunology, and also includes new information on immune-based therapeutic interventions and methods, such as phototherapy and the immunological therapy of skin cancer. The book contains Part I, with introductory chapters; Part II, with descriptions of the cellular elements; and Part III, which describes the humoral and molecular components of SIS. Part IV follows to integrate the facts described in Parts II and III into concepts of pathophysiology. It contains a number of concepts entitled "response patterns" that describe how the constitutional elements of SIS work together. New in this edition are the descriptions of immunodermatological diseases individually described in Part V. Part VI is also all new and summarizes principles of immunotherapy.
The present edition of The Human Central Nervous System differs considerably from its predecessors. In previous editions, the text was essentially confined to a section dealing with the various functional systems of the brain. This section, which has been rewritten and updated, is now preceded by 15 newly written chapters, which introduce the pictorial material of the gross anatomy, the blood vessels and meninges and the microstructure of its various parts and deal with the development, topography and functional anatomy of the spinal cord, the brain stem and the cerebellum, the diencephalon and the telencephalon. Great pains have been taken to cover the most recent concepts and data. As suggested by the front cover, there is a focus on the evolutionary development of the human brain. Throughout the text numerous correlations with neuropathology and clinical n- rology have been made. After much thought, we decided to replace the full Latin terminology, cherished in all previous editions, with English and Anglicized Latin terms. It has been an emotional farewell from beautiful terms such as decussatio hipposideriformis W- nekinkii and pontes grisei caudatolenticulares. Not only the text, but also the p- torial material has been extended and brought into harmony with the present state of knowledge. More than 230 new illustrations have been added and many others have been revised. The number of macroscopical sections through the brain has been extended considerably. Together, these illustrations now comprise a complete and convenient atlas for interpreting neuroimaging studies.
The domain of catalytic hydrogenation continues to grow fast, reflecting the wide range of chemical applications that can be enhanced by the easy use of molecular hydrogen. The advances in characterization techniques and their application have improved our understanding of the catalytic processes and mechanisms occurring in both homogeneous and heterogeneous catalysis. The aim of this volume, although not exhaustive, is to provide a general overview of new progress of the hydrogenation reactions. This volume comprises a series of various contributions, as reviews or original articles, treating heterogeneously and homogeneously catalyzed hydrogenation reactions. It is composed of three parts: hydrogenation reactions in fine organic chemistry, hydrogenation reactions in environmental chemistry and renewable energy, and special topics in hydrogenation.
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