In 1959, a college student, Matt, is contacted by his cousin who was presumed killed during the Korean War. His cousin invites him to spend the winter break at his parents’ remote lodge in northern Minnesota. Matt persuades two friends to join him and together, they drive to the lodge in a blinding blizzard. On arrival they are shocked to find a horror scene at the lodge. Matt’s two friends and the owner of the lodge disappear after a confrontation with Matt’s cousin, but Matt escapes. Matt is subsequently arrested and accused of murdering the occupants of the lodge including his two friends, his aunt and uncle. No evidence is found to convict Matt; however, he remains a person of interest and is restricted by the court to reside in a small town nearby. Years later, the lodge is acquired by a computer programmer and his friend, but on their initial visit to the property, they encounter several strange and frightening incidents that prompt them to investigate the history of the lodge. They find an article that details Matt’s account of the 1959 incident and set out to locate him in the small local town. After they locate Matt and compare notes, they discover that Matt’s cousin disappeared in northern Alaska. They then set out to locate the site of his cousin’s disappearance. After an arduous trip into the Brooks Range Mountains of northern Alaska, they are captured and find themselves in a large subterranean city.
This is the final volume in a three-volume work that has addressed the scientific methodologies relevant to clinical neurobehavioral toxicology. Volume I focused on basic concepts and methodologies in Neurobehavioral Toxicology, with Volume II focusing on the peripheral nervous system. Volume III attends to what is known about industrial and environmental chemicals, medicines, and substances of abuse and how these agents affect the central nervous system. All substances have the capacity to be toxic, depending on factors that include the physical properties of the chemical or compound, organism related variables, or interaction between the two. These substances on the other hand and as a result of these same factors might be used therapeutically or even recreationally. The difference between medicine, recreational drug, or poison depends often on a careful balance between adverse and intended effects. How to determine that a specified substance has caused harm is emphasized in the present volume by way of case examples and discussion. Illnesses and behavioral variations that compete with toxicant-induced explanations for findings in a given case, as well as the various controversies that can arise around issues of diagnosis and causal determination, are treated comprehensively in this volume.
During the last few years there has been a rapidly increasing interest in neural modeling of brain and cognitive disorders. This multidisciplinary book presents a variety of such models in neurology, neuropsychology and psychiatry. A review of work in this area is given first. Computational models are then presented of memory impairment in Alzheimer's disease, functional brain reorganization following a stroke, patterns of neural activity in epilepsy, disruption of language processes in aphasia and acquired dyslexia, altered cognitive processes in schizophrenia and depression, and related disorders. This is the first book on this topic, with contributions from many of the leading researchers in this field.
This book was conceived many years ago as an abstract goal for a father-son team when the father was working in university administration and the son was just getting into the academic business. Eventually, the father returned to the laboratory, the son began to get his feet on the ground, and the goal became concrete. Now the work is finished, and our book enters the literature as, we hope, a valuable contribution to understanding the terribly complex and subtle problem of the neuro biology of motivated behaviors. We would also like the book to stand as a personal mark of a cooperative relationship between father and son. This special relationship between the authors gave us an extra dimension of pleasure in writing the book, and it would delight us if it gave anyone else an extra dimension of enjoyment from reading it. One thing we hope happens is that anyone or simply considering entering similar considering a similar partnership, of this book as encouragement. Such re fields, will take the existence lationships are highly satisfying if both parties take care to protect the partnership. When we actually sat down to write the book, we were humbled by the immense literature and the smallness of both our conceived space for putting it down and of our brains for processing all the information.
This book, the first of three volumes, provides a thorough background to the emerging field of neurobehavioral toxicology by looking at current clinical approaches and tests, as well as assessing current clinical research. The analysis of the impact of toxins on the human nervous system is particularly pertinent given the ongoing expansion of pharmaceuticals, industrial hazards, biological warfare and global pollution. A comprehensive introduction to neurobehavioral toxicology, this work will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.
This book summarizes current knowledge of the neuropsychology of dementia, highlights the multifaceted nature of the problem, and argue that an input from neuropsychologists can facilitate the advances made by other neuroscientists
Dr. Lester Adelson's original The Pathology of Homicide has been described as a "superb textbook" and "without doubt…the best written book of its type in the English language" by Dr. Charles Hirsch. This new, revised edition preserves Dr. Adelson's eloquent and articulate voice, while bringing the subject matter up to date. Since the first edition was published in 1974, Dr. Adelson’s book was a treasured text among many forensic pathologists. The “aging” of the book, however, made it less appealing to the new generation of forensic pathologists, and Dr. Adelson’s important contribution to forensic pathology was at risk of being lost. Although much has changed in forensic pathology in the ensuing nearly fifty years since it was first written, much also has stayed the same. In this new edition, the author, Dr. James Gill—Chief Medical Examiner of the State of Connecticut and past president of the National Association of Medical Examiners—preserves the voice, vision, and wisdom of Dr. Adelson while updating the forensic pathology material. The author has included nearly 700 all new color images. In addition, the references have been updated with over 4,400 citations. Six new chapters and sections have been added, including death certification, elder abuse, pediatric head injury, drugs of misuse, histopathology, and bereavement. Other updates are included on DNA technology, CT scans, and novel drugs. Although primarily concerned with homicides, there is the need to be able to recognize natural, accidental, and suicidal deaths; therefore, these topics are interspersed in the text to give the appropriate context. This book will help the reader understand the details of injuries and how a person was injured, why they died, and how these injuries, perhaps at first blush seemingly insignificant, can shed new light on a death investigation. It is the author’s hope to get this book to the next generation of forensic pathologists.
In 1959, a college student, Matt, is contacted by his cousin who was presumed killed during the Korean War. His cousin invites him to spend the winter break at his parents’ remote lodge in northern Minnesota. Matt persuades two friends to join him and together, they drive to the lodge in a blinding blizzard. On arrival they are shocked to find a horror scene at the lodge. Matt’s two friends and the owner of the lodge disappear after a confrontation with Matt’s cousin, but Matt escapes. Matt is subsequently arrested and accused of murdering the occupants of the lodge including his two friends, his aunt and uncle. No evidence is found to convict Matt; however, he remains a person of interest and is restricted by the court to reside in a small town nearby. Years later, the lodge is acquired by a computer programmer and his friend, but on their initial visit to the property, they encounter several strange and frightening incidents that prompt them to investigate the history of the lodge. They find an article that details Matt’s account of the 1959 incident and set out to locate him in the small local town. After they locate Matt and compare notes, they discover that Matt’s cousin disappeared in northern Alaska. They then set out to locate the site of his cousin’s disappearance. After an arduous trip into the Brooks Range Mountains of northern Alaska, they are captured and find themselves in a large subterranean city.
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