This book is a compelling and balanced history of the California missions and their impact on the Indians they tried to convert. Focusing primarily on the religious conflict between the two groups, it sheds new light on the tensions, accomplishments, and limitations of the California mission experience. James A. Sandos, an eminent authority on the American West, traces the history of the Franciscan missions from the creation of the first one in 1769 until they were turned over to the public in 1836. Addressing such topics as the singular theology of the missions, the role of music in bonding Indians to Franciscan enterprises, the diseases caused by contact with the missions, and the Indian resistance to missionary activity, Sandos not only describes what happened in the California missions but offers a persuasive explanation for why it happened.
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.
A Columbia Law School team’s in-depth examination of one man’s 1989 wrongful conviction and execution for murder. In 1989, Texas executed Carlos DeLuna, a poor Hispanic man with childlike intelligence, for the murder of Wanda Lopez, a convenience store clerk. His execution passed unnoticed for years until a team of Columbia Law School faculty and students chose to investigate his case and found that DeLuna almost certainly was innocent. No one had cared enough about either the defendant or the victim to make sure the real perpetrator was found. Everything that could go wrong in a criminal case did. DeLuna’s conviction was based on a single, nighttime, cross-ethnic eyewitness identification with no corroborating forensic evidence. At his trial, DeLuna’s defense—that another Carlos had committed the crime—was not taken seriously. The lead prosecutor told the jury that the other Carlos, Carlos Hernandez, was a “phantom” of DeLuna’s imagination. In upholding the death penalty on appeal, both the state and federal courts concluded the same thing: Carlos Hernandez did not exist. However, he not only existed, but also had a long history of violent crimes . . . This book and its website (thewrongcarlos.net) reproduce law-enforcement, crime lab, lawyer, court, social service, media, and witness records, as well as court transcripts, photographs, radio traffic, and audio and videotaped interviews, documenting one of the most comprehensive investigations into a criminal case in US history. “This book will become a classic in the field.” —Austin Sarat, Amherst College “[An] infuriating yet engrossing book on wrongful conviction...An important critique of our legal system.” —Publishers Weekly
With unlimited archival access and a journalist's attention to detail, James L. Rogers updates and expands his 1965 publication to bring the university's history into the next century. The founder of the Texas Normal College, Joshua C. Chilton, declared in 1890 the institution's aim "to become leaders in the education of the young men and women of Texas, fitting them to creditably fill the most important positions in business and professional circles." By 1965 the eighth president, J. C. Matthews, presided over an institution granting doctorates in the sciences, mathematics, humanities, social sciences, teacher education, business administration, and the fine arts. In the last thirty-five years the institution has grown to become the University of North Texas System under the leadership of Chancellor Alfred Hurley and President Norval Pohl, with campuses in Dallas and Fort Worth. It now stands as the leading university of the Dallas/Fort Worth Metroplex. Generously illustrated with over eighty photos of people and events on campus, The Story of North Texas provides the definitive history of this institution and is an inspiration to its alumni and friends..
Through 10 outstanding editions, Kelley & Firestein's Textbook of Rheumatology has provided authoritative, in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. The 11th Edition of this classic text continues this tradition of excellence, while keeping you abreast of recent advances in genetics and the microbiome, new therapies such as biologics and biosimilars, and other rapid changes in the field. It provides comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, in a user-friendly, full color reference. - Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes—including key data on therapeutic outcomes to better inform clinical decision making. - Includes new chapters on Innate Lymphoid Cells and Natural Killer Cells, Pathogenesis of Inflammasome Mediated Diseases, Bisphosphonates, Ultrasound Evaluation of the Musculoskeletal System, and Evaluation of Monoarticular and Polyarticular Arthritis. - Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs. - Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editor Dr. Gary Koretzky, specialist in immunology and rheumatology. - Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
A fascinating and fun look at the Lone Star State’s history, culture, and people Texas is the country's second-largest state by size and population. It has a unique and varied history, having been ruled by a succession of nations—from which the term “six flags over Texas” sprang—before becoming an independent republic. From its traditional oil, cattle, and cotton industries to the modern energy, electronics, computer, aerospace, and biomedical industries, Texas has become an economic powerhouse. It’s known for its low taxes, diverse population, thriving universities, and art scenes. Exploring the state’s fascinating history, people, myths, culture, and trivia, The Handy Texas Answer Book takes an in-depth look at this fascinating and diverse state with the bigger-than-life personality. Learn about the original Indigenous peoples, the Spanish, French, and Mexican colonizations, the independence from Mexico, the ties to the Confederacy and United States, devastating hurricanes, football culture, fast-growing cities and urban sprawl, food, attitude, and much, much more. Tour landmarks from the Alamo and cattle ranches to the Rio Grande and the state capital. Learn about famous sons and daughters, including Lyndon Johnson, Sam Houston, Howard Hughes, Janis Joplin, and Renée Zellweger. Sports (both college and professional) are illuminated. The government, parks, and cultural institutions are all packed into this comprehensive guide to the state of Texas. Find answers to more than 850 questions, including: • What is the origin of “Howdy?” • Where in Texas can you find all three kinds of dinosaur tracks in one place? • Where can gold be found in Texas? • How did we come to have “Dr. Pepper”? • Is it true that Texas’s annexation to the United States was never really legal? • How did Texas women get to vote a year before women in the rest of the United States? • What Texan became the most-decorated soldier in World War II? • Is it true that the only Texas governor to die in office expired in the arms of his mistress? • How did Texas transform from solidly Democratic to solidly Republican? • How did the discovery of Texas oil change the face of American business? • How did rodeos originate? • What was the University of Texas mascot before there was Bevo the Longhorn? • What was the slightly dishonest secret of UT’s early success in baseball? • What is so special about the television show Austin City Limits? • What are the “Marfa Lights”? • How many Texas convicts have been freed after proving their innocence with DNA? • What is the Cuero Turkey Trot? Illustrating the unique character of the state through a combination of facts, stats, and history, as well as the unusual and quirky, The Handy Texas Answer Book answers intriguing questions about people, places, events, government, and places of interest. This informative book also includes a helpful bibliography and an extensive index, adding to its usefulness.
Published in cooperation with the William P. Clements Center for Southwest Studies, Southern Methodist University Ruins are as central to the image of the American Southwest as are its mountains and deserts, and antiquity is a key element of modern southwestern heritage. Yet prior to the mid-nineteenth century this rich legacy was largely unknown to the outside world. While military expeditions first brought word of enigmatic relics to the eastern United States, the new intellectual frontier was seized by archaeologists, who used the results of their southwestern explorations to build a foundation for the scientific study of the American past. In Ruins and Rivals, James Snead helps us understand the historical development of archaeology in the Southwest from the 1890s to the 1920s and its relationship with the popular conception of the region. He examines two major research traditions: expeditions dispatched from the major eastern museums and those supported by archaeological societies based in the Southwest itself. By comparing the projects of New York's American Museum of Natural History with those of the Southwest Museum in Los Angeles and the Santa Fe-based School of American Archaeology, he illustrates the way that competition for status and prestige shaped the way that archaeological remains were explored and interpreted. The decades-long competition between institutions and their advocates ultimately created an agenda for Southwest archaeology that has survived into modern times. Snead takes us back to the days when the field was populated by relic hunters and eastern "museum men" who formed uneasy alliances among themselves and with western boosters who used archaeology to advance their own causes. Richard Wetherill, Frederic Ward Putnam, Charles Lummis, and other colorful characters all promoted their own archaeological endeavors before an audience that included wealthy patrons, museum administrators, and other cultural figures. The resulting competition between scholarly and public interests shifted among museum halls, legislative chambers, and the drawing rooms of Victorian America but always returned to the enigmatic ruins of Chaco Canyon, Bandelier, and Mesa Verde. Ruins and Rivals contains a wealth of anecdotal material that conveys the flavor of digs and discoveries, scholars and scoundrels, tracing the origins of everything from national monuments to "Santa Fe Style." It rekindles the excitement of discovery, illustrating the role that archaeology played in creating the southwestern "past" and how that image of antiquity continues to exert its influence today.
A vast and desolate region, the Texas–New Mexico borderlands have long been an ideal setting for intrigue and illegal dealings—never more so than in the lawless early days of cattle trafficking and trade among the Plains tribes and Comancheros. This book takes us to the borderlands in the 1860s and 1870s for an in-depth look at Union-Confederate skullduggery amid the infamous Comanche-Comanchero trade in stolen Texas livestock. In 1862, the Confederates abandoned New Mexico Territory and Texas west of the Pecos River, fully expecting to return someday. Meanwhile, administered by Union troops under martial law, the region became a hotbed of Rebel exiles and spies, who gathered intelligence, disrupted federal supply lines, and plotted to retake the Southwest. Using a treasure trove of previously unexplored documents, authors James Bailey Blackshear and Glen Sample Ely trace the complicated network of relationships that drew both Texas cattlemen and Comancheros into these borderlands, revealing the urban elite who were heavily involved in both the legal and illegal transactions that fueled the region’s economy. Confederates and Comancheros deftly weaves a complex tale of Texan overreach and New Mexican resistance, explores cattle drives and cattle rustling, and details shady government contracts and bloody frontier justice. Peopled with Rebels and bluecoats, Comanches and Comancheros, Texas cattlemen and New Mexican merchants, opportunistic Indian agents and Anglo arms dealers, this book illustrates how central these contested borderlands were to the history of the American West.
Utilizing many sources new to publication, James L. Haley delivers a most readable and enjoyable narrative history of Texas, told through stories—the words and recollections of Texans who actually lived the state’s spectacular history. From Jim Bowie’s and Davy Crockett’s myth-enshrouded stand at the Alamo, to the Mexican-American War, and to Sam Houston’s heroic failed effort to keep Texas in the Union during the Civil War, the transitions in Texas history have often been as painful and tense as the “normal” periods in between. Here, in all of its epic grandeur, is the story of Texas as its own passionate nation. “Texas native Haley does an outstanding job of narrating the outsized and dramatic history of the Lone Star State. John Steinbeck observed, ‘Like most passionate nations, Texas has its own private history based on, but not limited by, facts.’ Cognizant of this, Haley takes pains to separate folklore from fact. He's a good storyteller, but then it's hard to go wrong with the colorful characters he has to work with: pioneer nationalists Sam Houston and Davy Crockett, Quaker abolitionist Benjamin Lundy, a wagonload of liquored-up turn-of-the-century oilmen and such latter-day heroes as Lyndon Johnson, John Connally and Janis Joplin.”—Publishers Weekly Starred Review
A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms
Praise for Bush's Brain "Love him or hate him, Karl Rove is one of the most brilliant and successful political consultants of all time. In this riveting account, Wayne Slater and Jim Moore tell how he got there." —Paul Begala, CNN's Crossfire "Bush's Brain isn't a hatchet job on George W. Bush. In fact, the two authors largely dispel the myth of Bush's supposedly deficient IQ. But, more importantly, they lay bare the story of how Karl Rove may be the most powerful man in America. It's a compelling story told by two veteran Texas journalists who don't need a briefing packet to understand the men they're writing about." —Philip Bruce, KCET/PBS Television, Los Angeles The most powerful individual in the United States may not be George W. Bush. It is probably Karl Rove, the President's brilliant advisor. Who is this man and how did he acquire so much power? Having watched in awe for over fifteen years as they reported on the rise of Karl Rove, Moore and Slater expose the brutal and sometimes morally questionable, but invariably effective ways in which Karl Rove?and America's political system—actually operate.
The success story of a much-decorated fighter pilot who overcame poverty and racism to become America's first African-American four-star general. Born in Pensacola, Florida, the youngest of seventeen children in a relatively poor family, "Chappie" James (1920-1978) rose to attain the rank of four-star general-the highest rank of the peacetime American military. His parents had early on imbued him with personal and national pride and a singular drive that motivated him his whole life. At Tuskegee Institute, James enrolled in the Army Air Corps unit formed to train black pilots. After combat service in World War II, James became the leader of a fighter group in the Korean War, during which he developed innovative tactics for providing close air support for advancing ground forces. He served with distinction in Vietnam and then became a public affairs officer in the Department of Defense. Between 1970 and 1974, James served as the Pentagon's chief spokesman to youth and civic organizations. General James's importance transcends his unprecedented achievements as an African American in the military and his role as a spokesman for the patriotic community. He was an early and important proponent of black self-improvement through education, training, and the tireless pursuit of excellence. He became the very embodiment of the American dream. First published in 1985 in hardcover, this reissue of Black Eagle in paperback makes the inspiring story of a notable Tuskegee airman available again.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Utilize the Latest Supportability Tools and Methods to Design Durable and Maintainable Systems Engineers in both the commercial and military sectors can rely on the Supportability Engineering Handbook for complete support criteria that ensure the performance of products ranging from automobiles to spacecraft. This one-of-a-kind resource offers the latest supportability tools and methods for designing complex systems that will last a long time and be easy to maintain in actual use. World-renowned supportability and logistics expert James V. Jones shows readers how to create supportable design solutions through effective system architecting, system and design engineering, and integration. He fully analyzes reliability, maintainability, and testability, and also explores every aspect of supportability. In addition, the author presents detailed coverage of reliability-centered maintenance...safety and human factors engineering...cost of ownership...supportability assessment and testing... configuration management and control...and much more. The Supportability Engineering Handbook features: Step-by-step guidelines for implementing supportability State-of-the-art measurement methods and tools A wealth of cutting-edge system design knowledge An expert critique of commercial off-the-shelf applications Achieve Optimal Supportability in the Design of Complex Systems • The Evolving Supportability Design Solution • Creating the Design Solution through System Architecting, System Engineering, Design Engineering, and Integration Engineering • Reliability, Maintainability, and Testability Engineering • Supportability Characteristics • Reliability Centered Maintenance • Safety and Human Factors Engineering • Cost of Ownership • Supportability Analysis • Supportability Assessment and Testing • Configuration Management and Control • Special Considerations: Software, Off the Shelf Items • Abbreviations and Acronyms • Glossary of Terms
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