This book presents a fascinating and self-contained account of "recruitment learning", a model and theory of fast learning in the neocortex. In contrast to the more common attractor network paradigm for long- and short-term memory, recruitment learning focuses on one-shot learning or "chunking" of arbitrary feature conjunctions that co-occur in single presentations. The book starts with a comprehensive review of the historic background of recruitment learning, putting special emphasis on the ground-breaking work of D.O. Hebb, W.A.Wickelgren, J.A.Feldman, L.G.Valiant, and L. Shastri. Afterwards a thorough mathematical analysis of the model is presented which shows that recruitment is indeed a plausible mechanism of memory formation in the neocortex. A third part extends the main concepts towards state-of-the-art spiking neuron models and dynamic synchronization as a tentative solution of the binding problem. The book further discusses the possible role of adult neurogenesis for recruitment. These recent developments put the theory of recruitment learning at the forefront of research on biologically inspired memory models and make the book an important and timely contribution to the field.
With the completion of the single market, an increasing number of unstructured information sources are available. This Directory is therefore aimed at providing practical and comprehensive guidance on EC business information sources in an accessible format. It provides information on legislative and consultative procedures and relevant published and organisational sources. Entries are arranged under NACE classification, the system which superseded the current UK SIC system during 1991. The Directory is an invaluable EC business reference source and complements its UK equivalent, The Macmillan Directory of Business Information Sources (UK), EC Industry.
Since it was first published in 1987, Galactic Dynamics has become the most widely used advanced textbook on the structure and dynamics of galaxies and one of the most cited references in astrophysics. Now, in this extensively revised and updated edition, James Binney and Scott Tremaine describe the dramatic recent advances in this subject, making Galactic Dynamics the most authoritative introduction to galactic astrophysics available to advanced undergraduate students, graduate students, and researchers. Every part of the book has been thoroughly overhauled, and many sections have been completely rewritten. Many new topics are covered, including N-body simulation methods, black holes in stellar systems, linear stability and response theory, and galaxy formation in the cosmological context. Binney and Tremaine, two of the world's leading astrophysicists, use the tools of theoretical physics to describe how galaxies and other stellar systems work, succinctly and lucidly explaining theoretical principles and their applications to observational phenomena. They provide readers with an understanding of stellar dynamics at the level needed to reach the frontiers of the subject. This new edition of the classic text is the definitive introduction to the field. ? A complete revision and update of one of the most cited references in astrophysics Provides a comprehensive description of the dynamical structure and evolution of galaxies and other stellar systems Serves as both a graduate textbook and a resource for researchers Includes 20 color illustrations, 205 figures, and more than 200 problems Covers the gravitational N-body problem, hierarchical galaxy formation, galaxy mergers, dark matter, spiral structure, numerical simulations, orbits and chaos, equilibrium and stability of stellar systems, evolution of binary stars and star clusters, and much more Companion volume to Galactic Astronomy, the definitive book on the phenomenology of galaxies and star clusters
Ideal for use in the clinic and in the field, Equine Emergencies: Treatment and Procedures, 4th Edition, offers practical step-by-step guidelines for effectively managing a wide range of emergency situations. Thoroughly updated content keeps you informed of the latest advances in horse care in a portable, convenient format. Essential examination, diagnostic, and treatment information for each body system is presented in a logical format so you can quickly find answers during equine emergencies. What to Do and What Not to Do boxes guide you through the step-by-step treatment of an emergency and draw your attention to important steps to take and those to avoid. High-quality photographs and illustrations visually clarify key concepts and guide you through procedures step by step. NEW! Chapter covering bacterial and viral diseases arms you with critical information on diagnostic labs, collection, submission, and interpretation. NEW! Chapter on emergency diagnostic procedures keeps you up-to-date on all the tests needed to determine the most effective treatment. NEW! Chapter on gene testing provides information on which gene tests and labs should be performed. NEW! Chapter on biopsy techniques highlights the different instruments available, endoscopic and laparoscopic techniques, as well as how to perform a pleuritis examination. NEW! Chapter on laboratory submission offers the latest information on tests, laboratory charts, guidelines for making an appropriate submission, and blood drawing. NEW! Chapters on feeding and starvation and flood injury supply the latest guidelines for nutrition, disaster medicine, and snake bites/envenomation.
- NEW! Chapter covering bacterial and viral diseases arms you with critical information on diagnostic labs, collection, submission, and interpretation. - NEW! Chapter on emergency diagnostic procedures keeps you up-to-date on all the tests needed to determine the most effective treatment. - NEW! Chapter on gene testing provides information on which gene tests and labs should be performed. - NEW! Chapter on biopsy techniques highlights the different instruments available, endoscopic and laparoscopic techniques, as well as how to perform a pleuritis examination. - NEW! Chapter on laboratory submission offers the latest information on tests, laboratory charts, guidelines for making an appropriate submission, and blood drawing. - NEW! Chapters on feeding and starvation and flood injury supply the latest guidelines for nutrition, disaster medicine, and snake bites/envenomation.
The process of inflammation, which causes the swelling and redness around a wound, is a vital part of the body's system for fighting off infections. When the body is hurt, the immune system produces chemical signals telling cells to multiply without dying, allowing skin to close over a gash, for example. Other chemicals spur the growth of new blood vessels to feed the recovering tissue. Scientists have linked inflammation to cancer and recently to heart disease in several ways. Doctors suspect that long-term inflammation or infection is involved in up to 20 per cent of cancers, including those of the oesophagus, colon, skin, stomach, liver, bladder, breast and some kinds of lymphoma. C-reactive protein (CRP) is one of the acute phase proteins that increase during systemic inflammation. It's been suggested that testing CRP levels in the blood may be a new way to assess cardiovascular disease risk. A high sensitivity assay for CRP test (hs-CRP) is now widely available. This book presents recent leading-edge research from around the world.
A sequel to the popular Zen and the Brain further explores pivotal points of intersection in Zen Buddhism, neuroscience, and consciousness, arriving at a new synthesis of information from both neuroscience research and Zen studies. This sequel to the widely read Zen and the Brain continues James Austin's explorations into the key interrelationships between Zen Buddhism and brain research. In Zen-Brain Reflections, Austin, a clinical neurologist, researcher, and Zen practitioner, examines the evolving psychological processes and brain changes associated with the path of long-range meditative training. Austin draws not only on the latest neuroscience research and new neuroimaging studies but also on Zen literature and his personal experience with alternate states of consciousness. Zen-Brain Reflections takes up where the earlier book left off. It addresses such questions as: how do placebos and acupuncture change the brain? Can neuroimaging studies localize the sites where our notions of self arise? How can the latest brain imaging methods monitor meditators more effectively? How do long years of meditative training plus brief enlightened states produce pivotal transformations in the physiology of the brain? In many chapters testable hypotheses suggest ways to correlate normal brain functions and meditative training with the phenomena of extraordinary states of consciousness. After briefly introducing the topic of Zen and describing recent research into meditation, Austin reviews the latest studies on the amygdala, frontotemporal interactions, and paralimbic extensions of the limbic system. He then explores different states of consciousness, both the early superficial absorptions and the later, major "peak experiences." This discussion begins with the states called kensho and satori and includes a fresh analysis of their several different expressions of "oneness." He points beyond the still more advanced states toward that rare ongoing stage of enlightenment that is manifest as "sage wisdom." Finally, with reference to a delayed "moonlight" phase of kensho, Austin envisions novel links between migraines and metaphors, moonlight and mysticism. The Zen perspective on the self and consciousness is an ancient one. Readers will discover how relevant Zen is to the neurosciences, and how each field can illuminate the other.
Psychology recognises no borders. The relationships between people and the groups they form are determined by similar principles no matter where in the world they come from. This book has been written to introduce students from all countries and backgrounds to the exciting field of social psychology. Recognising the limitations that come from studying the subject through the lens of any one culture, James Alcock and Stan Sadava have crafted a truly international social psychology book for the modern era. Based on classic and cutting-edge scholarship from across the world, An Introduction to Social Psychology encourages mastery of the basics as well as critical thinking. Incorporating relevant insights from social neuroscience, evolutionary theory and positive psychology, it offers: Chapters on crowd behaviour and applied social psychology Discussion of new means of social interaction, including social media Relevant insights from social neuroscience, evolutionary theory and positive psychology A companion website features extensive additional resources for students and instructors
This is a treatment of the phenomenology of galaxies. The text draws on observations of both our own galaxy, the Milky Way, and of external galaxies. It emphasizes the observational basis for current understanding of galactic astromony in the late '90s.
This second edition of the critically acclaimed core textbook provides students from technology and science based backgrounds with the theoretical knowledge and practical skills required to transform innovative ideas into commercially viable businesses for profit or social ends. Blending theory, policy and practice in a manner that is accessible to readers with little prior knowledge of business commercialisation, it offers a framework for understanding the entrepreneurial process for technological ideas. The book provides students with comprehensive guidance on the specialized field of 'technopreneurship'. It provides the tools and frameworks required for managing, commercialising and marketing technological innovation. With real life examples and case studies from a range of countries and industries, it will equip students with the understanding required to successfully launch their product. This text caters for undergraduate and postgraduate students studying technology entrepreneurship modules on engineering, science and computing technology programmes. New to this edition: -All chapters updated to reflect the evolution of theory and practice in the field -New cases on digital entrepreneurship, growth and scaling -Extended geographical coverage of case studies -Entrepreneurial practices updated to include recent research -Strategic context of business models, business growth and scaling, digital entrepreneurship, entrepreneurial marketing, organization design and crowdfunding developed and updated.
Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. James T. Cassidy, Ross E. Petty, Ronald M. Laxer, and Carol B. Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders. Choose treatment protocols based on the best scientific evidence available today. Apply the knowledge and experience of the leading experts in the field. Keep current with coverage of new topics including macrophage activation syndrome, pediatric sarcoidosis, uveitis, imaging, and occupational and physical therapy. Tap into detailed discussions of recent advances in the field, new research on the immunologic mechanisms of inflammatory disease, and new developments on biologic treatments for arthritis in ten new chapters. Master complex concepts and key techniques with a full-color design and full-color illustrations.
This title traces the history of US v. IBT (International Brotherhood of Teamsters), beginning with Giuliani's controversial lawsuit and continuing with in-depth analysis of the ups and downs of an unprecedented remedial effort involving the Department of Justice, the federal courts, and the IBT itself.
This text addresses the expanding role of resistance training for health, disease prevention and rehabilitation. It presents a clear and sound rationale for including resistance training as a health benefit, pointing out the areas in which it helps.
The fifth edition of this best-selling introductory text has been updated to reflect the latest trends and statistics in community health in an effort to effectively address the health issues facing today's communities. with emphasis on developing the knowledge and skills necessary for a career in health education, an Introduction to Community Health, Fifth Edition, covers such topics as epidemiology, community organization, program planning, minority health, health care, mental health, environmental health, drugs, safety, and occupational health.
James Reaney is one of Canada's favourite poets and playwrights; at the intersection of his dramatic and poetic talents is Scripts, a collection of musical writings. There are nine complete works here, including the chamber opera Night-blooming Cereus, the poetry/music collage (and Governor General's Award winner) Twelve Letters to a Small Town, the Canada Dot, Canada Dashtrilogy and operas Shivaree, Taptoo!and Serinette. Many of these pieces have been published individually, but none are in print, and they have never been amassed.
Carrying on the tradition established by its founding editor, the late Dr. Martin Abeloff, the 4th Edition of this respected reference synthesizes all of the latest oncology knowledge in one practical, clinically focused, easy-to-use volume. It incorporates basic science, pathology, diagnosis, management, outcomes, rehabilitation, and prevention – all in one convenient resource – equipping you to overcome your toughest clinical challenges. What's more, you can access the complete contents of this Expert Consult title online, and tap into its unparalleled guidance wherever and whenever you need it most! Equips you to select the most appropriate tests and imaging studies for diagnosing and staging each type of cancer, and manage your patients most effectively using all of the latest techniques and approaches. Explores all of the latest scientific discoveries' implications for cancer diagnosis and management. Employs a multidisciplinary approach - with contributions from pathologists, radiation oncologists, medical oncologists, and surgical oncologists - for well-rounded perspectives on the problems you face. Offers a user-friendly layout with a consistent chapter format • summary boxes • a full-color design • and more than 1,445 illustrations (1,200 in full color), to make reference easy and efficient. Offers access to the book's complete contents online – fully searchable – from anyplace with an Internet connection. Presents discussions on cutting-edge new topics including nanotechnology, functional imaging, signal transduction inhibitors, hormone modulators, complications of transplantation, and much more. Includes an expanded color art program that highlights key points, illustrates relevant science and clinical problems, and enhances your understanding of complex concepts.
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