In diesem Buch werden wertvolle Informationen zur Chemie der Tragerreagenzien dargeboten, die bisher in der chemischen Literatur oder in entsprechenden Abstracts nur sehr schwer zu finden waren. Materialien und deren Praparation, sowie Analysemethoden und Fallstudien werden ausfuhrlich beschrieben. In der Entwicklung von Tragerreagenzien und deren potentieller Anwendung in der organischen Synthese gab es in jungster Zeit einen regelrechten Boom. Ein ganz entscheidender Vorteil von Tragerreagenzien ist ihre Umweltvertraglichkeit. Sie stellen somit eine interessante Alternative zu den konventionellen Reagenzien dar, die korrodierend, unwirtschaftlich und vor allem schwer zu entsorgen sind.
This book functions as a workbook for consultants in pediatric anesthesia. Based on a curriculum developed at the Boston Children’s Hospital Department of Anesthesiology, the content illustrates the breadth and depth of the practice of pediatric anesthesia. Organized into two parts, the book seeks to provide a sense of progression and feedback using clinical scenarios to aid the medical professional in developing autonomy, while preserving the availability of expert level discussion. Each chapter features self-assessments in question and answer format, and encourages the reader to be creative in their responses by invoking not only their clinical knowledge, but their philosophical views of pediatric anesthesia practice as well. Practical and accessible, The Pediatric Anesthesiology Review is an essential resource for those looking to attain proficiency, expertise, and mastery in pediatric anesthesiology.
This text addresses the expanding role of resistance training for health, disease prevention and rehabilitation. It presents a clear and sound rationale for including resistance training as a health benefit, pointing out the areas in which it helps.
Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up. - Includes new chapters on Cancer Metabolism and Clinical Trial Designs in Oncology and a standalone chapter on lifestyles and cancer prevention. - Features extensive updates including the latest clinical practice guidelines, decision-making algorithms, and clinical trial implications, as well as new content on precision medicine, genetics, and PET/CT imaging. - Includes revised diagnostic and treatment protocols for medical management, surgical considerations, and radiation oncology therapies, stressing a multispecialty, integrated approach to care. - Helps you find information quickly with updated indexing related to management recommendations, focused fact summaries, updated key points at the beginning of each chapter ideal for quick reference and board review, and algorithms for patient evaluation, diagnosis, and treatment options. - Offers more patient care coverage in disease chapters, plus new information on cancer as a chronic illness and cancer survivorship. - Discusses today's key topics such as immuno-oncology, functional imaging, precision medicine, the application of genetics in pathologic diagnosis and sub-categorization of tumors as well as the association of chronic infectious diseases such as HIV and cancer. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.
Introducing HEMATOPATHOLOGY, a definitive new diagnostic reference on diseases of the hematopoietic system by Dr. Elaine S. Jaffe and her fellow editors, all collaborators on the World Health Organization's classification of lymphoid and myeloid disorders. These experts provide you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, equipping you to deliver more accurate and actionable pathology reports. More than 1,100 high-quality color images mirror the findings you encounter in practice. Overcome the toughest diagnostic challenges with authoritative guidance from the world's leading experts. Make optimal use of the newest diagnostic techniques, including molecular, immunohistochemical, and genetic studies. Compare specimens to more than 1,100 high-quality color images to confirm or challenge your diagnostic interpretations. Search the full contents online and download any of the images at expertconsult.com.
High Risk Pregnancy examines the full range of challenges in general obstetrics, medical complications of pregnancy, prenatal diagnosis, fetal disease, and management of labor and delivery. Drs. David James, Philip J. Steer, Carl P. Weiner, Bernard Gonik, Caroline Crowther, and Stephen Robson present an evidence-based approach to the available management options, equipping you with the most appropriate strategy for each patient. This comprehensive reference features the fully searchable text online at www.expertconsult.com, as well as more than 100 videos of imaging and monitoring. giving you easy access to the resources you need to manage high risk pregnancies. Prepare for clinical challenges and save time in addressing them thanks to expert advice on treatment options from international contributors. Find and apply the information you need quickly and easily through a consistent organization and at-a-glance summary boxes that discuss evidence-based management options. Access the fully searchable text online at www.expertconsult.com, along with links to Medline. View over 140 videos of detailed fetal imaging and monitoring that aid in diagnoses. Tap into recent developments in treatment and management in four new chapters—Global Maternal & Perinatal Health Issues; Recurrent Pregnancy Loss; Surveillance of the Fetus and its Indications; and Training for Obstetric Emergencies. Apply new evidence-based management options to treat genetic and constitutional factors leading to a high-risk pregnancy (such as diabetes, obesity, hypertension, and cardiac disease) through new and expanded coverage of these increasingly common presentations. Reference pregnancy-relevant laboratory values with an updated and comprehensive appendix on "Normal Values in Pregnancy." Effectively manage patients newly diagnosed with hematologic and immunologic malignancies, and explore the available drug options. Confirm your diagnoses with greater confidence thanks to full-color images throughout the text.
Waste minimisation has a number of aims which include enhancing the intrinsic selectivity of any given process, providing a means of recovering reagents in a form which allows easy regeneration and the replacement of stoichiometric processes with catalytic ones. Solids, as catalysts or as supports for other reagents, offer potential for benefit in all these areas. This monograph provides an overview of the properties of the more useful solid catalysts and supported reagents, and highlights their most valuable applications in the preparation of organic chemicals in liquid phase reactions. Clean Synthesis Using Porous Inorganic Solid Catalysts and Supported Reagents is concerned with the use of solid catalysts in the clean synthesis of organic chemicals. The emphasis is on chemical processes of importance to the manufacture/preparation of fine and speciality chemicals, chemical intermediates and pharmaceutical intermediates, especially where catalysis is not currently used or where current catalysts are homogeneous, leading to difficult separation procedures and unacceptable levels of waste. This book focuses on solid catalysts based on inorganic supports and covers the emerging area of chemically modified mesoporous solid catalysts.
**Selected for Doody's Core Titles® 2024 in Respiratory Therapy** Ensure you understand one of the most sophisticated areas of respiratory care with Pilbeam's Mechanical Ventilation: Physiological and Clinical Applications, 8th Edition! Known for its simple explanations and in-depth coverage of patient-ventilator management, this evidence-based text walks you through the most fundamental and advanced concepts surrounding mechanical ventilation and helps you understand how to properly apply these principles to patient care. This new edition is an excellent reference for all critical care practitioners and features coverage of the physiological effects of mechanical ventilation on different cross-sections of the population. Additionally, user-friendly features promote critical thinking and clinical application, such as key points, AARC clinical practice guidelines, critical care concepts, and updated learning objectives. - UNIQUE! Ventilator-Associated Pneumonia chapter presents in-depth, comprehensive coverage on this very challenging issue. - Critical Care Concepts present short questions that challenge you to apply knowledge learned to difficult concepts. - Brief patient case studies list pertinent assessment data and pose a critical thinking question to test your content comprehension. - Key Points draw attention to pivotal concepts and highlight important information as topics are addressed. - Intended for classroom or small group discussions, Clinical Scenarios offer a more comprehensive patient scenario that covers patient presentation, assessment data, and treatment options. - Logical sequencing of chapters builds on previously learned concepts. - Comprehensive Learning Objectives provide a clear, concise listing of what you need to learn in the chapter. - Bulleted end-of-chapter summaries help assess comprehension and guide study efforts. - Excerpts of Clinical Practice Guidelines developed by the American Association for Respiratory Care (AARC) are presented in a convenient, reader-friendly format. - Chapter outlines provide a "big picture" of the chapter content. - NBRC-style end-of-chapter review questions reinforce the very difficult concept of mechanical ventilation with practice that focuses on certification exam success. - Glossary of mechanical ventilation terminology provides definitions for highlighted key terms in each chapter. - UPDATED! Revised content throughout reflects the latest standards of respiratory care.
A comprehensive review of current endovascular techniques for the treatment of cerebral aneurysms, this is a practical manual for those practicing, or intending to practice, this rapidly expanding branch of minimally invasive surgery. The authors provide descriptions based on an extensive combined experience of clinical management, technical problems, complications and recent results, and discuss the limitations and role of combined extravasular/endovascular techniques.
This book is written by a team of speech and language therapists from The Wolfson Neurorehabilitation Centre. It is intended for practitioners working with patients who have acquired communication disorders resulting from brain injury: aphasia, cognitive-communication disorder, dysarthria, apraxia. The authors believe that a therapeutic programme should have it's foundations in the linguistic, non-verbal, neurological and neurospsychological perspective of the patient's difficulties. The approach the team has developed consists of several different strangs of therapy, with each strand representing an element of the rehabilitation process: assessment; goal planning; specific individualised treatment; education; friends and family; and psychosocial adjustment. This book describes these strands, illustrates in a user-friendly way how each one relates to therapy, and fives some practical ideas of how practitioners might work within them. Each chapter begins with the guiding principles and evidence bases that underlie the rationale for one particular strand of therapy. They then follow examples of practice and case studies of a real-life example of each strand. This book describes a speech and language therapy service that aims to be responsive to patients' needs and develops tailor-made intervention programmes that arer unique to each individual. It includes CD containing assessments and practical tools.
Since the early seventies, European thinkers have departed notably from their predecessors in order to pursue analytical programs more thoroughly their own. Rethinking the Subject brings together in one volume some of the most influential writings of Foucault, Habermas, Bourdieu, Pizzorno, Macfarlane, and other authors whose ideas have had a worldwide influence in recent social theory. This anthology is testament to the central importance of three contemporary themes, each familiar to earlier thinkers but never definitively formulated or resolved. The first two concern the nature and modalities of power and legitimacy in society. The third, and most fundamental, deals with the nature and modalities of the "self" or "subject." These themes owe their special contemporary relevance to an array of events— from the collapse of colonialism to the birth of test-tube babies. James Faubion's introduction traces the historical context of these influential events and themes. It also traces the lineaments of a still inchoate intellectual movement, of which the anthology's contributors are the vanguard. Whether "modernist" or "post-modernist," this movement leads away from a "world-constituting subject," which in one guise or another has served as the ontological ground of social reflection and research since Kant. It points instead toward ontological pluralism and toward polythetic diagnostics of heterogeneous forces that constitute a multiplicity of worlds and subjects.
The environmental sciences are undergoing a revolution in the use of models and data. Facing ecological data sets of unprecedented size and complexity, environmental scientists are struggling to understand and exploit powerful new statistical tools for making sense of ecological processes. In Models for Ecological Data, James Clark introduces ecologists to these modern methods in modeling and computation. Assuming only basic courses in calculus and statistics, the text introduces readers to basic maximum likelihood and then works up to more advanced topics in Bayesian modeling and computation. Clark covers both classical statistical approaches and powerful new computational tools and describes how complexity can motivate a shift from classical to Bayesian methods. Through an available lab manual, the book introduces readers to the practical work of data modeling and computation in the language R. Based on a successful course at Duke University and National Science Foundation-funded institutes on hierarchical modeling, Models for Ecological Data will enable ecologists and other environmental scientists to develop useful models that make sense of ecological data. Consistent treatment from classical to modern Bayes Underlying distribution theory to algorithm development Many examples and applications Does not assume statistical background Extensive supporting appendixes Lab manual in R is available separately
For some time I have been preparing a general work on primitive superstition and religion. Among the problems which had attracted my attention was the hitherto unexplained rule of the Arician priesthood; and last spring it happened that in the course of my reading I came across some facts which, combined with others I had noted before, suggested an explanation of the rule in question. As the explanation, if correct, promised to throw light on some obscure features of primitive religion, I resolved to develop it fully, and, detaching it from my general work, to issue it as a separate study. This book is the result. Now that the theory, which necessarily presented itself to me at first in outline, has been worked out in detail, I cannot but feel that in some places I may have pushed it too far. If this should prove to have been the case, I will readily acknowledge and retract my error as soon as it is brought home to me. Meantime my essay may serve its purpose as a first attempt to solve a difficult problem, and to bring a variety of scattered facts into some sort of order and system. A justification is perhaps needed of the length at which I have dwelt upon the popular festivals observed by European peasants in spring, at midsummer, and at harvest. It can hardly be too often repeated, since it is not yet generally recognised, that in spite of their fragmentary character the popular superstitions and customs of the peasantry are by far the fullest and most trustworthy evidence we possess as to the primitive religion of the Aryans. Indeed the primitive Aryan, in all that regards his mental fibre and texture, is not extinct. He is amongst us to this day. The great intellectual and moral forces which have revolutionised the educated world have scarcely affected the peasant. In his inmost beliefs he is what his forefathers were in the days when forest trees still grew and squirrels played on the ground where Rome and London now stand.
New edition of a text in which six researchers from leading institutions discuss what is known and what is yet to be understood in the field of cell biology. The material on molecular genetics has been revised and expanded so that it can be used as a stand-alone text. A new chapter covers pathogens, infection, and innate immunity. Topics include introduction to the cell, basic genetic mechanisms, methods, internal organization of the cell, and cells in their social context. The book contains color illustrations and charts; and the included CD-ROM contains dozens of video clips, animations, molecular structures, and high-resolution micrographs. Annotation copyrighted by Book News Inc., Portland, OR.
Accompanying CD-ROM includes 600 figures, tables and color plates from the book Plants in action which can be used for the production of color transparencies or for projections in lectures.
Dr. James Wright, Associate Editor for the Journal of Bone and Joint Surgery, presents this landmark publication and novel approach to orthopaedic problems and solutions. This new, evidence-based reference examines clinical options and discusses relevant research evidence to provide you with expert recommendations for best practice. The consistent chapter format and featured summary tables provide "at-a-glance? access to the evidence-based literature and clinical options. Leading authorities contribute their expertise so you can apply the most effective clinical solutions to the persistent questions you encounter in your practice. You can even access the fully searchable and regularly updated text online The result is an outstanding resource in clinical orthopaedics, as well as a valuable framework for translating evidence into practice.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
This open access book... There is significant interest in the Philosophy of Science community to understand the role that "effective theories" have in the work of forefront science. The ideas of effective theories have been implicit in science for a long time, but have only been articulated well in the last few decades. Since Wilson's renormalization group revolution in the early 1970's, the science community has come to more fully understand its power, and by the mid-1990's it had gained its apotheosis. It is still one of the most powerful concepts in science, which has direct impact in how one thinks about and formulates theories of nature. It is this power that this Brief sets out to emphasize through historical analysis and current examples. This is an open access book.
Offering highly visual, easy-to-read coverage of the full range of anesthesia equipment in use today, this authoritative reference is your go-to text for objective, informed answers to ensure optimal patient safety. Anesthesia Equipment, 3rd Edition, provides detailed information on the intricate workings of each device or workstation, keeping you fully up to date and helping you meet both equipment and patient care challenges. - Remains unequalled in both depth and breadth of coverage, offering readable, concise guidance on all aspects of today's anesthesia machines and equipment. - Details the latest machines, vaporizers, ventilators, breathing systems, vigilance, ergonomics, and simulation. - Improves your understanding of the physical principles of equipment, the rationale for its use, delivery systems for inhalational anesthesia, systems monitoring, hazards and safety features, maintenance and quality assurance, special situations/equipment for non-routine adult anesthesia, and future directions for the field. - Includes ASA Practice Parameters for care, and helps you ensure patient safety with detailed advice on risk management and medicolegal implications of equipment use. - Highlights the text with hundreds of full-color line drawings and photographs, graphs, and charts. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This comprehensive compendium of current knowledge in the fields of otology/neurotology, rhinology, facial plastic and reconstructive surgery, paediatric otorhinolaryngology, head and neck surgery and bronchoesophagology features sections on facial plastic, reconstructive surgery and paediatrics. The content reflects the central responsibility of the otorhinolaryngologist in treating patients with diseases affecting the senses of smell, taste and balance. Also encompassed in this section are treatments for disorders of human communication affecting hearing, voice, speech and language.
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