Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
Adaptive survey designs (ASDs) provide a framework for data-driven tailoring of data collection procedures to different sample members, often for cost and bias reduction. People vary in how likely they are to respond and in how they respond. This variation leads to opportunities to selectively deploy design features in order to control both nonresponse and measurement errors. ASD aims at the optimal matching of design features and the characteristics of respondents given the survey budget. Such a goal is sensible, but ASD requires investment in more advanced technical systems and management infrastructure and asks for the collection of relevant auxiliary data. So what are current best practices in ASD? And is ASD worthwhile when the same auxiliary data are employed in the estimation afterwards? In this book, the authors provide answers to these questions, and much more.
Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Algorithms for line finding, fitting spectra to voigtian profiles, filtering, Fourier transforming, and spectrum synthesis are a basis for spectrum analysis tools from which complex signal-processing procedures can be constructed.".
This book chronicles the history and development of cucurbiturils. It provides a general introduction and a field-wide overview of the synthesis, properties and applications of cucurbiturils.Beginning with a chronicled history in the development of the once little-known peculiarity to the forefront of supramolecular chemistry, followed by an in depth look at the preparation, properties and host-guest chemistry, the title showcases the uses of cucurbiturils in chemistry, materials science and biology.An essential resource for both new and experienced researchers, as it provides an overview of the diverse applications, new methodologies and research, as well as challenges in the field.
More than half a century has passed since man first stood on the summit of Mount Everest, and the story of man's attempts to climb higher and higher unaided is one of the more colourful and exciting in medicine and physiology. The past few decades have seen an explosion in the interest in mountain pursuits in general, as increasing numbers of peopl
This comprehensive compendium of current knowledge in the fields of otology/neurotology, rhinology, facial plastic and reconstructive surgery, paediatric otorhinolaryngology, head and neck surgery and bronchoesophagology features sections on facial plastic, reconstructive surgery and paediatrics. The content reflects the central responsibility of the otorhinolaryngologist in treating patients with diseases affecting the senses of smell, taste and balance. Also encompassed in this section are treatments for disorders of human communication affecting hearing, voice, speech and language.
Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine. - Provides a new and versatile method to fabricating living tissue - Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction - Describes current approaches and future challenges for translational science - Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms
Still the most widely used comprehensive resource in orthopaedic surgery, Campbell's Operative Orthopaedics is an essential reference for trainees, a trusted clinical tool for practitioners, and the gold standard for worldwide orthopaedic practice. Unparalleled in scope and depth, this 14th Edition contains updated diagnostic images, practical guidance on when and how to perform every procedure, and rapid access to data in preparation for surgical cases or patient evaluation. Drs. Frederick M. Azar and James H. Beaty, along with other expert contributors from the world-renowned Campbell Clinic, have collaborated diligently to ensure that this 4-volume text remains a valuable resource in your practice, helping you achieve optimal outcomes with every patient. - Features evidence-based surgical coverage throughout to aid in making informed clinical choices for each patient. - Covers multiple procedures for all body regions to provide comprehensive coverage. - Keeps you up to date with even more high-quality procedural videos, a new chapter on biologics in orthopaedics, and expanded and updated content on hip arthroscopy, patellofemoral arthritis and more. - Follows a standard template for every chapter that features highlighted procedural steps, high-quality illustrations for clear visual guidance, and bulleted text. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices
Even after more than two centuries, mystery continues to surround Meriwether Lewis’s death—did the famous explorer commit suicide or was he murdered? Recently revealed truths and deconstructed myths are woven together in this fascinating account to form an unforgettable tale of political corruption, assassins, forged documents, and skeletal remains. New research implicating General James Wilkinson—commanding general of the U.S. Army and coconspirator of Aaron Burr—as the assassin is thoroughly discussed, while riveting testimony from 13 leading experts in wound ballistics, forensic anthropology, suicide psychology, grave-site exhumation, and handwriting analysis offers new insight into what Lewis’s exhumed remains might reveal. The new evidence not only destroys the foundation of suicide arguments by proving the primary evidence is a forgery, it also proves the Indian Agent escorting Lewis lied about his activities on the day of Lewis's death. The book also contains evidence of a previously unknown plot by Aaron Burr to seize New Orleans and invade Mexico in 1809, a repeat of his 1806 plot. It explains why Lewis suddenly changed his plans to travel to Washington, DC, by boat, and instead chose to go overland on the Natchez Trace, where he met his untimely death on October 11, 1809, at age 35.
Recently revealed truths and deconstructed myths are woven together in this fascinating account to form an unforgettable tale of political corruption, assassins, forged documents, and skeletal remains.
Providing vital updates, this two volume set describes the central role and aim of health care needs assessment in the NHS health care reforms, and explains the 'epidemiological approach' to needs assessment, and the effectiveness and availability of services.
This is the first edition of a unique new plastics industry resource: Who's Who in Plastics & Polymers. It is the only biographical directory of its kind and includes contact, affiliation and background information on more than 3300 individuals who are active leaders in this industry and related organizations. The biographical directory is i
For some time immunotherapy has been heralded as a breakthrough approach for cancer treatment. Although the potential of this strategy remains solid, the approach needs considerable refinement. Whilst some programmes are looking to increase the understanding of molecular and cellular mechanisms underlying the stimulation of antitumor immunity, others are trying to find the most appropriate clinical setting that will reveal the role of the immune system in combating cancer. Among the most important discoveries have been tumor-specific antigens. This thematic volume highlights some key issues and discusses where they may move forward. It has been put together by two leading cancer immunotherapists from two eminent institutions that focus on cancer research.
The Power to Learn: The Benefits and the Promise of Personalized Instruction advances the notion that personalized instruction is the direction that schools must take if all students are expected to succeed with difficult learning challenges. Based on the premise that all students are capable, this book offers practical information so that schools can be designed or redesigned to meet individual students where they are academically and to challenge them toward deeper learning. Unlocking their capability is best accomplished by implementing a process labeled DPIE: diagnosis, prescription, implementation, and evaluation. Examples dating back to the early 20th century are described that show the idea is derived from historical antecedents and twenty-two research-based strategies and tactics are offered. Also included are five exemplary schools from preschool to high school.
Representing the state of the art in evolutionary paleobiology, this book provides a much-needed overview of this rapidly changing field. An influx of ideas and techniques both from other areas of biology and from within paleobiology itself have resulted in numerous recent advances, including increased recognition of the relationships between ecological and evolutionary theory, renewed vigor in the study of ecological communities over geologic timescales, increased understanding of biogeographical patterns, and new mathematical approaches to studying the form and structure of plants and animals. Contributors to this volume—a veritable who's who of eminent researchers—present the results of original research and new theoretical developments, and provide directions for future studies. Individually wide ranging, these papers all share a debt to the work of James W. Valentine, one of the founders of modern evolutionary paleobiology. This volume's unified approach to the study of life on earth will be a major contribution to paleobiology, evolution, and ecology.
This book shows how mathematics, computer science and science can be usefully and seamlessly intertwined. It begins with a general model of cognitive processes in a network of computational nodes, such as neurons, using a variety of tools from mathematics, computational science and neurobiology. It then moves on to solve the diffusion model from a low-level random walk point of view. It also demonstrates how this idea can be used in a new approach to solving the cable equation, in order to better understand the neural computation approximations. It introduces specialized data for emotional content, which allows a brain model to be built using MatLab tools, and also highlights a simple model of cognitive dysfunction.
From pioneering family-based treatment developer James Lock, this is the first comprehensive guide to adolescent-focused therapy (AFT) for anorexia nervosa (AN), an evidence-based individual approach. AFT is an effective alternative to family-based treatment that may be a better fit for some patients. Lock explains how AN serves as a maladaptive response to developmental challenges of adolescence. He presents a manualized framework for helping adolescents find more adaptive coping strategies, manage difficult emotions, and develop greater autonomy and a stronger sense of self, while reducing risky behaviors and restoring weight. AFT emphasizes the therapist–patient alliance and involves parents in a supportive role. Rich case material and sample dialogues illustrate how to implement each phase of the approach. AFT is recognized as a best practice for the treatment of anorexia nervosa in adolescents by the U.K. National Institute for Health and Care Excellence (NICE).
The Wechsler Intelligence Scale is the most widely used intelligence test for children worldwide. WISC-V introduces new subtests, composite scores, process scores, error scores, and scaled scores as a more complex and accurate means of assessing cognitive abilities. WISC-V Assessment and Interpretation provides practical information for clinicians on selection of subtest measures, administration, and interpretation. New subtests are described along with tips for accurate administration and scoring. Full Scale IQ is identified as important for predicting relevant behaviors, and primary index scores for characterizing the child's strengths and weaknesses. Classroom indicators of low scores on each of these abilities are identified, with suggested interventions, accommodations, and instructional strategies for low scorers. Coverage includes ethnic differences for the Full Scale IQ and each primary index score, along with evidence of the profound influence of parental attitudes and expectations. Several other societal and contextual factors relevant to understanding racial/ethnic differences are presented. Two chapters review use of the WISC-V for identifying learning disabilities, testing of individuals with dyslexia, and best-practice recommendations to ensure accurate diagnosis and intervention. Concluding chapters describe advances in the Q-interactive system platform allowing administration of the WISC-V on iPads and other tablets and how clinicians can tailor assessment using select WISC-V subtests and features. - Authored by the creators of the WISC-V - Describes the new subtests, revised test structure, and test extensions - Advises clinicians on test selection and custom tailoring of assessment measures - Provides best practice recommendations for accurate administration and scoring - Addresses electronic administration via tablets and comparison to print scores - Reviews social/contextual factors for understanding racial/ethnic differences - Translates scores to predict behaviors and identify child strengths and weaknesses - Suggests interventions, accommodations, and instructional strategies for low scorers
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