Silicon-On-Insulator (SOI) CMOS technology has been regarded as another major technology for VLSI in addition to bulk CMOS technology. Owing to the buried oxide structure, SOI technology offers superior CMOS devices with higher speed, high density, and reduced second order effects for deep-submicron low-voltage, low-power VLSI circuits applications. In addition to VLSI applications, and because of its outstanding properties, SOI technology has been used to realize communication circuits, microwave devices, BICMOS devices, and even fiber optics applications. CMOS VLSI Engineering: Silicon-On-Insulator addresses three key factors in engineering SOI CMOS VLSI - processing technology, device modelling, and circuit designs are all covered with their mutual interactions. Starting from the SOI CMOS processing technology and the SOI CMOS digital and analog circuits, behaviors of the SOI CMOS devices are presented, followed by a CAD program, ST-SPICE, which incorporates models for deep-submicron fully-depleted mesa-isolated SOI CMOS devices and special purpose SOI devices including polysilicon TFTs. CMOS VLSI Engineering: Silicon-On-Insulator is written for undergraduate senior students and first-year graduate students interested in CMOS VLSI. It will also be suitable for electrical engineering professionals interested in microelectronics.
Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases. By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners. - Explains the processes inherent in the protein quality control for pathogenesis and complications of cardiometabolic diseases - Provides knowledge from internationally recognized contributors in the field - Incorporates a translational approach, covering the basic cellular biology of autophagy and presenting the role of autophagy regulation for both pathogenesis and complication in cardiometabolic diseases - Contains access to a companion website with additional illustrations
Holland Frei Cancer Medicine serves as a quick reference to current information on an extensive list of cancers, including breast, lung, thyroid, colorectal, ovarian, prostate, and gastric cancer, to name but a few. Presented as an accessible pocket-sized handbook, the chapters are organized in an outline format, offering only the most essential information on the etiology, staging (including TNM staging) and treatment for each cancer type. Individual chapters are devoted to the molecular biology of cancer, cancer prevention, cancer screening, the mechanisms of chemotherapy, and diagnostic imaging in cancer. Additionally, each chapter lists all the major phase III clinical trials, and therefore, serves as an excellent reference of the major randomized controlled trials for each cancer reported to date. Specific chapters are also dedicated to the discussion of oncologic emergencies, pain and palliation, and prescription complications. At the conclusion of the book, a glossary of oncologic terms and chemotherapeutic drug programs, a table of common cancer incidences, and an overview of the mechanisms, common uses, and related toxicities of various anti-cancer agents are featured. In addition, performance status tables, mathematical formulas and a listing of common biomedical / cancer web sites are highlighted.
Still the most widely used comprehensive resource in orthopaedic surgery, Campbell's Operative Orthopaedics is an essential reference for trainees, a trusted clinical tool for practitioners, and the gold standard for worldwide orthopaedic practice. Unparalleled in scope and depth, this 14th Edition contains updated diagnostic images, practical guidance on when and how to perform every procedure, and rapid access to data in preparation for surgical cases or patient evaluation. Drs. Frederick M. Azar and James H. Beaty, along with other expert contributors from the world-renowned Campbell Clinic, have collaborated diligently to ensure that this 4-volume text remains a valuable resource in your practice, helping you achieve optimal outcomes with every patient. - Features evidence-based surgical coverage throughout to aid in making informed clinical choices for each patient. - Covers multiple procedures for all body regions to provide comprehensive coverage. - Keeps you up to date with even more high-quality procedural videos, a new chapter on biologics in orthopaedics, and expanded and updated content on hip arthroscopy, patellofemoral arthritis and more. - Follows a standard template for every chapter that features highlighted procedural steps, high-quality illustrations for clear visual guidance, and bulleted text. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices
Many nanomaterials exhibit anti-microbial properties and demand for such materials grows as new applications are found in such areas as medicine, environmental science and specialised coatings. This book documents the most up to date research on the area of nanoparticles showing anti-microbial activity and discusses their preparation and characterisation. Further materials showing potential anti-microbial properties are also discussed. With its user-friendly approach to applications, this book is an excellent reference for practical use in the lab. Its emphasis on material characterisation will benefit both the analytical and materials scientist. Frequent references to the primary literature ensure that the book is a good source of information to newcomers and experienced practitioners alike. Chapters devoted to nanoparticles, microbial impacts on surfaces and molecular biology are essential reading, while chapters on characterisation ensure this book stands out in the field.
Carrying on the tradition established by its founding editor, the late Dr. Martin Abeloff, the 4th Edition of this respected reference synthesizes all of the latest oncology knowledge in one practical, clinically focused, easy-to-use volume. It incorporates basic science, pathology, diagnosis, management, outcomes, rehabilitation, and prevention – all in one convenient resource – equipping you to overcome your toughest clinical challenges. What's more, you can access the complete contents of this Expert Consult title online, and tap into its unparalleled guidance wherever and whenever you need it most! Equips you to select the most appropriate tests and imaging studies for diagnosing and staging each type of cancer, and manage your patients most effectively using all of the latest techniques and approaches. Explores all of the latest scientific discoveries' implications for cancer diagnosis and management. Employs a multidisciplinary approach - with contributions from pathologists, radiation oncologists, medical oncologists, and surgical oncologists - for well-rounded perspectives on the problems you face. Offers a user-friendly layout with a consistent chapter format • summary boxes • a full-color design • and more than 1,445 illustrations (1,200 in full color), to make reference easy and efficient. Offers access to the book's complete contents online – fully searchable – from anyplace with an Internet connection. Presents discussions on cutting-edge new topics including nanotechnology, functional imaging, signal transduction inhibitors, hormone modulators, complications of transplantation, and much more. Includes an expanded color art program that highlights key points, illustrates relevant science and clinical problems, and enhances your understanding of complex concepts.
The Definitive, Comprehensive Guide to Cutting-Edge Millimeter Wave Wireless Design “This is a great book on mmWave systems that covers many aspects of the technology targeted for beginners all the way to the advanced users. The authors are some of the most credible scholars I know of who are well respected by the industry. I highly recommend studying this book in detail.” —Ali Sadri, Ph.D., Sr. Director, Intel Corporation, MCG mmWave Standards and Advanced Technologies Millimeter wave (mmWave) is today's breakthrough frontier for emerging wireless mobile cellular networks, wireless local area networks, personal area networks, and vehicular communications. In the near future, mmWave products, systems, theories, and devices will come together to deliver mobile data rates thousands of times faster than today's existing cellular and WiFi networks. In Millimeter Wave Wireless Communications, four of the field's pioneers draw on their immense experience as researchers, entrepreneurs, inventors, and consultants, empowering engineers at all levels to succeed with mmWave. They deliver exceptionally clear and useful guidance for newcomers, as well as the first complete desk reference for design experts. The authors explain mmWave signal propagation, mmWave circuit design, antenna designs, communication theory, and current standards (including IEEE 802.15.3c, Wireless HD, and ECMA/WiMedia). They cover comprehensive mmWave wireless design issues, for 60 GHz and other mmWave bands, from channel to antenna to receiver, introducing emerging design techniques that will be invaluable for research engineers in both industry and academia. Topics include Fundamentals: communication theory, channel propagation, circuits, antennas, architectures, capabilities, and applications Digital communication: baseband signal/channel models, modulation, equalization, error control coding, multiple input multiple output (MIMO) principles, and hardware architectures Radio wave propagation characteristics: indoor and outdoor applications Antennas/antenna arrays, including on-chip and in-package antennas, fabrication, and packaging Analog circuit design: mmWave transistors, fabrication, and transceiver design approaches Baseband circuit design: multi–gigabit-per-second, high-fidelity DAC and ADC converters Physical layer: algorithmic choices, design considerations, and impairment solutions; and how to overcome clipping, quantization, and nonlinearity Higher-layer design: beam adaptation protocols, relaying, multimedia transmission, and multiband considerations 60 GHz standardization: IEEE 802.15.3c for WPAN, Wireless HD, ECMA-387, IEEE 802.11ad, Wireless Gigabit Alliance (WiGig)
Understanding the thermal degradation of polymers is of paramount importance for developing a rational technology of polymer processing and higher-temperature applications. Controlling degradation requires understanding of many different phenomena, including chemical mechanisms, the influence of polymer morphology, the complexities of oxidation chemistry, and the effects of stabilisers, fillers and other additives. This book offers a wealth of information for polymer researchers and processors requiring an understanding of the implications of thermal degradation on material and product performance.
New motion-preserving devices are revolutionizing spine surgery...but the learning curve for these operations is steep, and great attention must be given to patient and device selection and the perfect execution of each procedure. Only one reference spells out exactly how to perform these new techniques...and its peerless author team, comprised of key investigators involved in the devices' actual clinical trials, is uniquely qualified to help you get the best results! These global leaders in this area discuss the advantages and disadvantages of the full range of non-fusion technologies...and present the step-by-step, richly illustrated operative guidance you need to achieve optimal outcomes! Select the best device and approach for each patient! * cervical total disc arthroplasty * lumbar total disc arthroplasty * lumbar partial disc replacement: nucleus replacement * lumbar posterior dynamic stabilization: pedicle screw based * lumbar posterior dynamic stabilization: interspinous based * lumbar facet replacement Produce optimal outcomes with detailed advice on... * advantages and disadvantages of each option * indications and contraindications * patient selection * interpretation of imaging studies * surgical anatomy and biomechanics * surgical techniques * tips and pearls See how to perform each technique, thanks to step-by-step, full-color illustrations
Polysiloxanes are the most studied inorganic and semi-inorganic polymers because of their many medical and commercial uses. The Si-O backbone endows polysiloxanes with intriguing properties: the strength of the Si-O bond imparts considerable thermal stability, and the nature of the bonding imparts low surface free energy. Prostheses, artificial organs, objects for facial reconstruction, vitreous substitutes in the eyes, and tubing take advantage of the stability and pliability of polysiloxanes. Artificial skin, contact lenses, and drug delivery systems utilize their high permeability. Such biomedical applications have led to biocompatibility studies on the interactions of polysiloxanes with proteins, and there has been interest in modifying these materials to improve their suitability for general biomedical application. Polysiloxanes examines novel aspects of polysiloxane science and engineering, including properties, work in progress, and important unsolved problems. The volume, with ten comprehensive chapters, examines the history, preparation and analysis, synthesis, characterization, and applications of these polymeric materials.
Asphalt is a complex but popular civil engineering material. Design engineers must understand these complexities in order to optimize its use. Whether or not it is used to pave a busy highway, waterproof a rooftop or smooth out an airport runway, Asphalt Materials Science and Technology acquaints engineers with the issues and technologies surrounding the proper selection and uses of asphalts. With this book in hand, researchers and engineering will find a valuable guide to the production, use and environmental aspect of asphalt. - Covers the Nomenclature and Terminology for Asphalt including: Performance Graded (PG) Binders, Asphalt Cement (AC), Asphalt-Rubber (A-R) Binder, Asphalt Emulsion and Cutback Asphalt - Includes Material Selection Considerations, Testing, and applications - Biodegradation of Asphalt and environmental aspects of asphalt use
With increasing emphasis being placed on screening and early prevention in cancer, this textbook examines the various methods and interventions used in screening in lung cancer, and presents a detailed review of the approaches to prevention and treatment of early disease. It will be of particular interest to lung cancer and respiratory medicine spe
The Cognitive Behavioural Analysis System of Psychotherapy (CBASP) is the only psychotherapy model developed specifically for chronic depression. In the latest addition to the successful Distinctive Features series, the developer of CBASP, James P. McCullough Jr., along with Elisabeth Schramm and J. Kim Penberthy, provides an accessible introduction to this approach, showing how it differs from other cognitive behavioural approaches, and highlighting those features – both theoretical and practical – that make it unique. The unparalleled problems of the chronically depressed patient are some of the most difficult that practitioners face. The disorder has usually continued for a decade or more and patients enter psychotherapy interpersonally withdrawn, detached and with little or no motivation to change. CBASP as A Distinctive Treatment for Persistent Depressive Disorder provides a new look into the phenomenological world of the patient and shows the reader why the world-view of the patient is a valid perception of reality. CBASP is designed to address the problems of the patient in a step-by-step manner. This book explores the therapist role and shows how the CBASP model enables therapists to address the patient’s depression in a zone of interpersonal safety. Patients are taught how to behave in an interpersonally facilitative manner and shown how everything they do has consequences for others (including the therapist) and on the social environment in which they live. CBASP as A Distinctive Treatment for Persistent Depressive Disorder will be essential reading for novice and experienced CBT therapists, counselors and psychotherapists treating chronic depression.
The New York Times has called the work of the Polshek Partnership a "triumph of substance over flash," and New Yorker Paul Goldberger has lauded the firm's ability to create meaningful works that demonstrate that "architecture can be an enriching force in life." This long-awaited monograph is published as the firm celebrates its fortieth anniversary. Guided by a respect for the environment, the innovative use of materials and technology, a progressive aesthetic vision, and its collaborative structure, the Polshek Partnership has produced a catalog of public worksnbsp;-- from theaters sand museums to libraries, hospitals, and schoolsnbsp;-- that collectively ennoble our civic life on a daily basis. In this handsomely produced volume, sixteen, of the partnership's most important works are examined in depth from initial conception through design, construction, and completion. These works include the celebrated Rose Center for Earth and Space at the American Museum of Natural History, the New York Times Printing Plant, and the Ed Sullivan Theater adaptation for David Letterman's Late Show. The book also documents seven of the firm's most recent projects, including the Clinton Presidential Library, Scandinavia House, and Zankel Hall at Carnegie Hall.
With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses
This book is open access under a CC BY-NC 4.0 license. The third edition of this indispensable book in radio interferometry provides extensive updates to the second edition, including results and technical advances from the past decade; discussion of arrays that now span the full range of the radio part of the electromagnetic spectrum observable from the ground, 10 MHz to 1 THz; an analysis of factors that affect array speed; and an expanded discussion of digital signal-processing techniques and of scintillation phenomena and the effects of atmospheric water vapor on image distortion, among many other topics. With its comprehensiveness and detailed exposition of all aspects of the theory and practice of radio interferometry and synthesis imaging, this book has established itself as a standard reference in the field. It begins with an overview of the basic principles of radio astronomy, a short history of the development of radio interferometry, and an elementary discussion of the operation of an interferometer. From this foundation, it delves into the underlying relationships of interferometry, sets forth the coordinate systems and parameters to describe synthesis imaging, and examines configurations of antennas for multielement synthesis arrays. Various aspects of the design and response of receiving systems are discussed, as well as the special requirements of very-long-baseline interferometry (VLBI), image reconstruction, and recent developments in image enhancement techniques and astrometric observations. Also discussed are propagation effects in the media between the source and the observer, and radio interference, factors that limit performance. Related techniques are introduced, including intensity interferometry, optical interferometry, lunar occultations, tracking of satellites in Earth orbit, interferometry for remote Earth sensing, and holographic measurements of antenna surfaces. This book will benefit anyone who is interested in radio interferometry techniques for astronomy, astrometry, geodesy, or electrical engineering.
The first introductory book on the subject, this book will provide a complete grounding to this pioneering field for students and professionals across biomedical engineering, biology and medicine. It features a comprehensive overview of original work in this revolutionary field. Topics discussed include drug delivery, cell-material interaction and gene therapy, accompanied by real-world examples and over 100 illustrations. The book teaches readers how to design and test their own nanomedical systems for real-world applications in biomedical engineering, medicine and pharmacy. Presenting a thorough discussion of the science and engineering of nanomedicine, it discusses vital environmental, social and ethical impacts of this revolutionary technology. Including over 200 thought-provoking study questions, allowing the reader to self-assess their understanding, this book is a rich source of information that will be of interest and importance in nanomedicine.
Introduction to Solid State Chemistry provides a strong background to the structures of solids and factors that determine this structure. The content presented will also stress transformations of solids both in physical forms and chemical composition. In so doing, topics such as phase transitions, sintering, reactions of coordination compounds, photovoltaic compounds are described, whilst kinetics and mechanisms of solid state reactions are covered in depth. There are currently few books that deal with solid state chemistry, where a considerable number instead deal with solid state physics and materials science/engineering. This book provides someone needing or wishing to learn about the chemistry of solids a comprehensive resource that describes structures of solids, the behaviour of solids under applied stresses, the types of reactions that solids undergo, and the phenomenological aspects of reactions in solids. Kinetics of reactions in solids is very seldom covered in current literature and an understanding of the mechanisms of reactions in solids is necessary for many applications. James E. House provides a balanced treatment of structure, dynamics, and behaviour of solids at a level commensurate with upper-level undergraduates or beginning graduate students who wish to obtain an introduction and overview to solid state chemistry. - Provides a?fundamental introduction and entry point to solid state chemistry, acting as a useful prerequisite for further learning in the area - Presents a balanced approach that not only emphasizes structures of solids but also provides information on reactions of solids and how they occur - Gives much-needed focus to the kinetics of reactions of solids and their mechanisms where existing literature covers little of this - Explores crucial solid state chemistry topics such as solar energy conversion, reactions of solid coordination compounds, diffusion, sintering, and other transformations of solids - Features accessible and well-written examples and case studies featuring many new and bespoke supporting illustrations, offering an excellent framework that will help students to understand reaction mechanisms
This book presents a fascinating and self-contained account of "recruitment learning", a model and theory of fast learning in the neocortex. In contrast to the more common attractor network paradigm for long- and short-term memory, recruitment learning focuses on one-shot learning or "chunking" of arbitrary feature conjunctions that co-occur in single presentations. The book starts with a comprehensive review of the historic background of recruitment learning, putting special emphasis on the ground-breaking work of D.O. Hebb, W.A.Wickelgren, J.A.Feldman, L.G.Valiant, and L. Shastri. Afterwards a thorough mathematical analysis of the model is presented which shows that recruitment is indeed a plausible mechanism of memory formation in the neocortex. A third part extends the main concepts towards state-of-the-art spiking neuron models and dynamic synchronization as a tentative solution of the binding problem. The book further discusses the possible role of adult neurogenesis for recruitment. These recent developments put the theory of recruitment learning at the forefront of research on biologically inspired memory models and make the book an important and timely contribution to the field.
The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.
This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins have and continue to offer remarkable opportunities for research, commercial development and outside confirmation of therapeutic, diagnostic and new paradigms to help explain complex biological processes.
Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
Introduction to Enhanced Recovery Methods for Heavy Oil and Tar Sands, Second Edition, explores the importance of enhanced oil recovery (EOR) and how it has grown in recent years thanks to the increased need to locate unconventional resources such as heavy oil and shale. Unfortunately, petroleum engineers and managers aren't always well-versed in the enhancement methods that are available when needed or the most economically viable solution to maximize their reservoir's productivity. This revised new edition presents all the current methods of recovery available, including the pros and cons of each. Expanded and updated as a great preliminary text for the newcomer to the industry or subject matter, this must-have EOR guide teaches all the basics needed, including all thermal and non-thermal methods, along with discussions of viscosity, sampling, and the technologies surrounding offshore applications. - Enables users to quickly learn how to choose the most efficient recovery method for their reservoir while evaluating economic conditions - Presents the differences between each method of recovery with newly added real-world case studies from around the world - Helps readers stay competitive with the growing need of extracting unconventional resources with new content on how these complex reservoirs interact with injected reservoir fluids
Employing the clear, student-friendly style that made previous editions so popular, Insect Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide to the latest findings in the dynamic field of insect physiology. The book supplies a comprehensive picture of the current state of the function, development, and reproduction of insects. Expanded and updated, now in full colour, this fourth edition adds three new chapters on the role of the nervous system in behavior; the ‘Genomics Revolution’ in entomology; and global climate changes which have a major effect on insects, including warming and weather. It continues to challenge conventional entomological wisdom with the latest research and analytical interpretations. The text will appeal to upper undergraduate and graduate students and to practicing biologists who need to possess a firm knowledge of the broad principles of insect physiology. With detailed full colour illustrations to help explain physiological concepts and important anatomical details, it remains the most easily accessible guide to key concepts in the field.
Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine. - Provides a new and versatile method to fabricating living tissue - Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction - Describes current approaches and future challenges for translational science - Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms
Focusing on fundamental principles, Hydro-Environmental Analysis: Freshwater Environments presents in-depth information about freshwater environments and how they are influenced by regulation. It provides a holistic approach, exploring the factors that impact water quality and quantity, and the regulations, policy and management methods that are necessary to maintain this vital resource. It offers a historical viewpoint as well as an overview and foundation of the physical, chemical, and biological characteristics affecting the management of freshwater environments. The book concentrates on broad and general concepts, providing an interdisciplinary foundation. The author covers the methods of measurement and classification; chemical, physical, and biological characteristics; indicators of ecological health; and management and restoration. He also considers common indicators of environmental health; characteristics and operations of regulatory control structures; applicable laws and regulations; and restoration methods. The text delves into rivers and streams in the first half and lakes and reservoirs in the second half. Each section centers on the characteristics of those systems and methods of classification, and then moves on to discuss the physical, chemical, and biological characteristics of each. In the section on lakes and reservoirs, it examines the characteristics and operations of regulatory structures, and presents the methods commonly used to assess the environmental health or integrity of these water bodies. It also introduces considerations for restoration, and presents two unique aquatic environments: wetlands and reservoir tailwaters. Written from an engineering perspective, the book is an ideal introduction to the aquatic and limnological sciences for students of environmental science, as well as students of environmental engineering. It also serves as a reference for engineers and scientists involved in the management, regulation, or restoration of freshwater environments.
“Extraordinary. . . . Both therapist and patient will benefit hugely from reading this book.” —Deepak Chopra “Exactly what this over-medicated country needs right now.” —Christine Northrup, M.D., author of The Wisdom of Menopause Despite the billions spent on prescription anti-depressant drugs and psychotherapy, people everywhere continue to grapple with depression. James Gordon, one of the nation's most respected psychiatrists, now offers a practical and effective way to get unstuck. Drawing on forty years of pioneering work, Unstuck is Gordon's seven-stage program for relief through food and nutritional supplements; Chinese medicine; movement, exercise, and dance; psychotherapy, meditation, and guided imagery; and spiritual practice. The result is a remarkable guide that puts the power to change in the hands of those ready to say "no" to suffering and drugs and "yes" to hope and happiness.
The unquestioned leader in dermatopathology resources, Weedon’s Skin Pathology returns with expanded and updated coverage in this specialized field of pathology. Offering an enhanced emphasis on differential diagnosis, new author Dr. James W. Patterson provides the most clinically relevant developments in molecular biology and techniques while maintaining Dr. Weedon's consistent, uniform approach to the subject. From practitioners and specialists to pathologists and dermatologists, this medical reference book is an essential addition to any dermatopathological library. Explore in-depth and updated topics covering clinically relevant developments in molecular biology and molecular techniques. Easily comprehend complex issues with improved illustrations focusing on rare conditions and unusual manifestations. Accurately interpret difficult specimens through an increased emphasis on differential diagnosis. Take advantage of expanded content in sections including Drug Reactions, Tumors, and Infections and Infestations. Consult this title on your favorite e-reader.
This book develops and details a rigorous, canonical modeling approach for analyzing spatio-temporal brain wave dynamics. The nonlinear, nonstationary behavior of brain wave measures and general uncertainty associated with the brain makes it difficult to apply modern system identification techniques to such systems. While there is a substantial amount of literature on the use of stationary analyses for brain waves, relatively less work has considered real-time estimation and imaging of brain waves from noninvasive measurements. This book addresses the issue of modeling and imaging brain waves and biomarkers generally, treating the nonlinear and nonstationary dynamics in near real-time. Using a modal state-space formulation leads to intuitive, physically significant models which are used for analysis and diagnosis. A Modal Approach to the Space-Time Dynamics of Cognitive Biomarkers provides a much-needed reference for practicing researchers in biomarker modeling leveraging the lens of engineering dynamics.
Focusing on the embedded press system deployed during Operation Iraqi Freedom, this book attempts to answer the following questions: How effective was the embedded press system in meeting the needs of the three main constituencies-the press, the military, and the citizens of the United States? What policy history led to the innovation of an embedded press system? Where are press-military relations likely to go in the future?
Feigin and Cherry's Textbook of Pediatric Infectious Diseases helps you put the very latest knowledge to work for your young patients with unparalleled coverage of everything from epidemiology, public health, and preventive medicine through clinical manifestations, diagnosis, treatment, and much more. Ideal for all physicians, whether in an office or hospital setting, Feigin and Cherry’s equips you with trusted answers to your most challenging clinical infectious disease questions. Meet your most difficult clinical challenges in pediatric infectious disease, including today’s more aggressive infectious and resistant strains as well as emerging and re-emerging diseases, with unmatched, comprehensive coverage of immunology, epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. Find the answers you need quickly thanks to an organization both by organ system and by etiologic microorganism, allowing you to easily approach any topic from either direction.
A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms
Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.
This book on solid state chemistry presents studies of chemical, structural, thermodynamic, electronic, magnetic, and optical properties and processes in solids. Research areas include: bonding in solids, crystal chemistry, crystal growth mechanisms, diffusion epitaxy, high-pressure processes, magnetic properties of materials, optical characterisation of materials, order-disorder, phase equilibria and transformation mechanisms, reactions at surfaces, statistical mechanics of defect interactions, structural studies and transport phenomena.
With thirty revised and updated chapters the new edition of this classic text brings benefits to professors and students alike who will find new sections on many topics concerning modern food microbiology. This authoritative book builds on the trusted and established sections on food preservation by modified atmosphere, high pressure and pulsed electric field processing. It further covers food-borne pathogens, food regulations, fresh-cut produce, new food products, and risk assessment and analysis. In-depth references, appendixes, illustrations, index and thorough updating of taxonomies make this an essential for every food scientist.
Precision Measurement of Microwave Comprehensive resource covering the foundations and analysis of precision noise measurements with a detailed treatment of their uncertainties Precision Measurement of Microwave Thermal Noise presents the basics of precise measurements of thermal noise at microwave frequencies and guides readers through how to evaluate the uncertainties in such measurement. The focus is on measurement methods used at the U.S. National Institute of Standards and Technology (NIST), but the general principles and methods are useful in a wide range of applications. Readers will learn how to perform accurate microwave noise measurements using the respected author’s expertise of calculations to aid understanding of the challenges and solutions. The text covers the background required for the analysis of the measurements and the standards employed to calibrate radiofrequency and microwave radiometers. It also covers measurements of noise temperature (power) and the noise characteristics of amplifiers and transistors. In addition to the usual room-temperature two-port devices, cryogenic devices and multiport amplifiers are also discussed. Finally, the connection of these lab-based measurements to remote-sensing measurement (especially from space) is considered, and possible contributions of the lab-based measurements to remote-sensing applications are discussed. Specific topics and concepts covered in the text include: Noise-temperature standards, covering ambient standards, hot (oven) standards, cryogenic standards, and other standards and noise sources Amplifier noise, covering definition of noise parameters, measurement of noise parameters, uncertainty analysis for noise-parameter measurements, and simulations and strategies On-wafer noise measurements, covering on-wafer microwave formalism, noise temperature, on-wafer noise-parameter measurements, and uncertainties Multiport amplifiers, covering formalism and noise matrix, definition of noise figure for multiports, and degradation of signal-to-noise ratio Containing some introductory material, Precision Measurement of Microwave Thermal Noise is an invaluable resource on the subject for advanced students and all professionals working in (or entering) the field of microwave noise measurements, be it in a standards lab, a commercial lab, or academic research.
How and why human males evolved the capacity to be highly involved caregivers—and why some are more involved than others. We all know the importance of mothers. They are typically as paramount in the wild as they are in human relationships. But what about fathers? In most mammals, including our closest living primate relatives, fathers have little to no involvement in raising their offspring—and sometimes even kill the offspring sired by other fathers. How, then, can we explain modern fathers having the capacity to be highly engaged parents? In Father Nature, James Rilling explores how humans have evolved to endow modern fathers with this potential and considers why this capacity evolved in humans. Paternal caregiving is advantageous to children and, by extension, to society at large, yet variable both across and within human societies. Rilling considers how to explain this variability and what social and policy changes might be implemented to increase positive paternal involvement. Along the way, Father Nature also covers the impact fathers have on children’s development, the evolution of paternal caregiving, how natural selection adapted male physiology for caregiving, and finally, what lessons an expecting father can take away from the book, as well as what benefits they themselves get from raising children, including increased longevity and “younger” brains. A beautifully written book by a father himself, Father Nature is a much-needed—and deeply rewarding—look at the science behind “good” paternal behavior in humans.
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