Rang and Dale's Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. - Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines - Clear figures to aid understanding, including data figures as well as mechanistic diagrams, - Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts - Emphasis on therapeutic drugs to help apply theory to practice - Over 150 questions and 12 clinical cases to test your knowledge - New chapters on drugs and the eye and the pharmacological management of headache - Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. - A completely revised and updated chapter on lifestyle drugs - Recent advances in oxygen sensing and response to reduced oxygen tension - Expanded chapters on dementia and analgesic drugs
A history of American cameramen covering the news of World War I, from the dangerous front line and the risk of execution to red tape and censorship. At the start of hostilities in World War I, when the United States was still neutral, American newsreel companies and newspapers sent a new kind of journalist, the film correspondent, to Europe to record the Great War. These pioneering cameramen, accustomed to carrying the Kodaks and Graflexes of still photography, had to lug cumbersome equipment into the trenches. Facing dangerous conditions on the front, they also risked summary execution as supposed spies while navigating military red tape, censorship, and the business interests of the film and newspaper companies they represented. Based on extensive research in European and American archives, American Cinematographers in the Great War, 1914–1918 follows the adventures of these cameramen as they managed to document and film the atrocities around them in spite of enormous difficulties. “The first book to explore the work and working conditions of American cinematographers active on the different fronts of the First World War. It is a pioneering study which has already attracted a good deal of attention in the academic and archive world.” —Historical Journal of Film, Radio and Television
Many view the IRS compliance and collection programs (CCP) -- such as audits to determine whether taxpayers have accurately reported the amount of taxes that they owe and collection follow-up with taxpayers who have not paid what is owed -- as critical for maintaining the public's confidence in our tax system. But declines in CCP have been dramatic. From FY 1996-2000, the number of individual tax returns audited by IRS declined by over 60%. Further, IRS was unable to pursue many delinq. taxpayers. This report: describes the changes since 1996 in IRS CCP, and the factors contributing to the changes; determines how the program changes have affected taxpayers; and determines how IRS addressed the program changes in its strategic assessments. Also includes a 17-page report, "Tax Deductions: Further Estimates of Taxpayers Who May Have Overpaid Federal Taxes by Not Itemizing.
Rang and Dale's Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. - Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines - Clear figures to aid understanding, including data figures as well as mechanistic diagrams, - Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts - Emphasis on therapeutic drugs to help apply theory to practice - Over 150 questions and 12 clinical cases to test your knowledge - New chapters on drugs and the eye and the pharmacological management of headache - Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. - A completely revised and updated chapter on lifestyle drugs - Recent advances in oxygen sensing and response to reduced oxygen tension - Expanded chapters on dementia and analgesic drugs
What does it look and feel like to be worshipful? Can we find a way to worship in such a robust, thoughtful way that when we aren't in worship, the worship might linger and invigorate us? Is it possible to live in the world--doing the dishes, listening to music, being stuck in traffic, enmeshed in a thicket of meetings at work--with a serene, abiding sense of God's presence despite all the racket, that we might do whatever we do for God, and sense God's presence? And maybe more importantly: could all we do between Sundays--grocery shopping, paying bills, listening to music, taking a walk, visiting aging parents--actually enrich and inform what we do on Sunday morning, making worship itself more vigorous, profound, just plain real, and memorable, and thus heightening the likelihood that the worship will linger through the rest of the week? This book is about living a worshipful life: understanding why we do what we do in Sunday morning worship, and then re-enacting those moods and actions all week long.
Rang & Dale’s Pharmacology provides you with all the knowledge you need to get through your pharmacology course and beyond. Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson present a clear and accessible approach to the analysis of therapeutic agents at the cellular and molecular level through detailed diagrams, full-color illustrations, and pedagogical features. Find and cross-reference information quickly using a color-coded layout that makes navigation easy. Effectively understand and review key concepts through detailed diagrams and full-color illustrations that clarify even the most complex concepts. Reinforce your learning with key points boxes and clinical uses boxes that highlight crucial information and clinical applications. Apply current best practices and clinical applications through thoroughly updated and revised drug information. Stay current with the latest developments in the field thanks to major updates in chapters such as How Drugs Act; Amino Acid Transmitters; Analgesic Drugs; Antidepressant Drugs; and Drug Addiction, Dependence & Abuse. Tap into comprehensive content tailored to your courses with new and reorganized chapters on Host Defense; Inflammatory Mediators; Pharmacogenetics, Pharmacogenomics & Personalized Medicine; Hydroxytoptomine & The Pharmacy of Migraine; and Purines.
When Franklin D. Roosevelt was inaugurated in March 1933, the White House staff numbered fewer than fifty people. In the ensuing years, as the United States became a world power and both the foreign and domestic duties of the president grew more complex, the White House staff has increased twentyfold. This books asks how best to manage a presidency that itself has become a bureaucracy. In the third edition of Organizing the Presidency, Stephen Hess, with the assistance of James P. Pfiffner, surveys presidential organizations from Roosevelt¡¯s to George W. Bush¡¯s, examining the changing responsibilities of the executive branch jobs and their relationships with one another, Capitol Hill, and the permanent government. He also describes the kinds of people who have filled these positions and the intentions of the presidents who appointed them.
Route 6 in Massachusetts runs from Provincetown to Seekonk and passes through some of the most beautiful scenery in the state. Route 6 winds its way around tiny fishing villages, sand dunes, marshes, beaches, lighthouses, campgrounds, hotels, restaurants, and historic cities. The combination of Route 6 and the automobile would make Cape Cod a world-renowned tourist destination.
There is no doubt that the task of preaching can sometimes be overwhelming. Combining veteran wisdom, practicality, and a contagious reverence for the beauty of God's Word, veteran pastor James C. Howell leads pastors and teachers through the joyful and perplexing craft and practice of preaching. Drawing on a wide range of resources, Howell provides discussions on the "Subject Matters of Preaching," "Where Sermons Happen," "When Sermons Happen," and the "Life of the Body." The conclusion on "The Preaching Self" considers the person of the preacher. These seasoned reflections will be of great help for all who preach.
Diagnose oral diseases quickly and accurately! Oral Pathology: Clinical Pathologic Correlations, 7th Edition presents diseases and conditions by appearance and presentation, so that you can easily identify and plan treatment for common oral and paraoral problems. An atlas-style overview of pathologic conditions opens the book, and then each chapter describes pathologies in detail - depicting each with full-color clinical photos and photomicrographs. In addition to covering the latest advances in oral pathology, this edition includes new radiographic images demonstrating advanced imaging techniques. Expert educators Joseph Regezi, James Sciubba, and Richard Jordan provide a quick reference that's ideal for the lab, NBDE review, or chairside use! Organization of oral and maxillofacial diseases by clinical appearance - such as red-blue lesions or pigmented lesions - matches what you would expect to see upon a patient's presentation, and provides a practical tool for developing differential diagnoses and planning treatment. Nearly 1,000 full-color clinical photographs, photomicrographs, radiographs, and drawings help you learn to identify lesions and disease states. An atlas-style Clinical Overview section makes it easy to find key information, with one page showing clinical photos of common conditions and the facing page listing symptoms, causes, and significance. Nearly 200 summary boxes and tables offer clear, at-a-glance information on the clinical features, diagnosis, and treatment for many conditions. Correlation of histopathology with clinical features of oral diseases assists the clinician in recognizing specific conditions and developing differential diagnoses and rational treatment approaches. Student resources on an Evolve companion website include 30 case studies, interactive lecture modules, and a 150-question practice exam to prepare you for the NBDE and for clinical practice. UPDATED content reflects current information and the latest advances in oral and maxillofacial pathology.
A devastating, compelling account of the federal government's leading role in bringing about today's climate crisis. In 2015, a group of twenty-one young people sued the federal government in Juliana v. United States for violating their constitutional rights by promoting climate catastrophe and thereby depriving them of life, liberty, and property without due process and equal protection of law. They Knew offers evidence supporting the children's claims, presenting a devastating and compelling account of the federal government's role in bringing about today's climate crisis. James Gustave Speth, tapped by the plaintiffs as one of twenty-one preeminent experts in their climate case, analyzes how administrations from Carter to Trump—despite having information about the impending climate crisis and the connection to fossil fuels—continued aggressive support of a fossil fuel based energy system. What did the federal government know and when did it know it? Speth asks, echoing another famous cover-up. What did the federal government actively do and what did it fail to do? They Knew (an updated version of the Expert Report Speth prepared for the lawsuit) presents the most definitive indictment yet of the US government's role in the climate crisis. Since Juliana v. United States was filed, the federal government has repeatedly taken unprecedented steps to delay the case and force it to the appellate courts' shadow dockets. Yet as the case progresses slowly but certainly, it is inspiring a generation of youthful climate activists. An Our Children's Trust Book
Gregory reaches into the migrants' lives to reveal both their economic trials and their impact on California's culture and society. He traces the development of an 'Okie subculture' which is now an essential element of California's cultural landscape.
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