Diseases of the Liver and Biliary System continues to be the pre-eminent textbook of choice for trainee as well as practising gastroenterologists who want a clear and lucid description of the very latest issues in this growing discipline. Every chapter has been updated with the most recent advances in the study and control of hepatitis, in its various forms. Technical and therapeutic advances have appeared in all areas of hepatology, in particular portal hypertension, liver tumours, genetic diseases and imaging, both diagnostic and therapeutic. All are brought up-to-date in the very readable style characteristic of this standard text.
On the night of November 4th 1605, the English authorities uncovered an alleged plot by a group of discontented Catholics to blow up the Houses of Parliament with the lords, princes, queen and king in attendance. The failure of the plot is celebrated to this day and is known as Guy Fawkes Day. In Poets, Players and Preachers, Anne James explores the literary responses to the discovery of the Gunpowder Plot in poetry, drama, and sermons. This book is the first full-length study of the literary repercussions of the conspiracy. By analyzing the genres of poems, plays, and sermons produced between 1605 and 1688, the author argues that not only did the continuous reinterpretation of the conspiracy serve religious and political purposes but that such literary reinterpretations produced generic changes.
Monoclonal Antibodies now have applications in virtually all areas of biology and medicine, and much of the world's biotechnology industry has its foundations in the exploitation of this technology. The Third Edition of this well established book meets the needs of both newcomers to the area and experienced researchers, by providing an integrated treatment of both the production and application of monoclonal antibodies. As in previous editions, detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies are given, along with descriptions of their use in antigen characterization, affinity chromatography and immunofluorescence. The present volume has been comprehensively updated to cover recent rapid advances, particularly with respect to the applications of molecular biology, the use of antibodies in closing and heterologous expression of genes, immunohistology and phage display libraries. Since the previous edition, there has been a growing trend towards the replacement of procedures using radioactive isotopes, and the current edition incorporates these newer technologies. The text is oriented towards problems solving, and makes it easy to adapt each procedure to individual needs. Extensive cross-referencing, a glossary and a comprehensive index make this book an essential reference. This book will be vital both for laboratories already producing or using monoclonal antibodies, and for workers in many disciplines who are contemplating their use. - Provides an integrated treatment of both the production and application of monoclonals in cell biology, biochemistry, and immunology - Gives detailed and critical accounts of the theory, production, purification, storage, and relabelling of monoclonals, and their use in antigen characterization, affinity chromorography, and immunofluroscence - Comprehensively updated to cover the rapid advances that have occurred since the publication of the Second Edition
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