Canadian literature was born in New York City. It began not in the backwoods of Ontario or the salt flats of New Brunswick, but in the cafés, publishing offices, and boarding houses of late nineteenth-century New York, where writing developed as a profession and where the groundwork for the Canadian canon was laid. So argues Nick Mount in When Canadian Literature Moved to New York. The last decades of the nineteenth century saw an extraordinary exodus from English Canada, draining the country of half its writers and all but a few of its contemporary and future literary celebrities. Motivated by powerful obstacles to a domestic literature, most of these migrants landed in New York - by the 1890s the centre of the continental literary market - and found for the first time a large, receptive literary market and recognition from non-Canadian publishers and reviewers. While the expatriates of the 1880s and 1890s - including Bliss Carman, Ernest Thompson Seton, and Palmer Cox - were recognized for their achievements in Canada, the domestic literature they themselves spurred into existence rekindled a nationalist imperative to distinguish Canadian writing from other literatures, especially American, and this slowly eliminated most of their work from the emerging English Canadian canon. When Canadian Literature Moved to New York is the story of these expatriate writers: who they were, why they left, what they achieved, and how they changed Canadian literary history.
How can we safely and effectively treat musculoskeletal disorders in this fast-growing population? Musculoskeletal Drug Therapy for Geriatric Patients is an essential reference for pharmacists, physicians, and nurses who plan treatment for elderly patients suffering from post-menopausal osteoporosis, osteoarthritis, rheumatoid arthritis, and gout or hyperuricemia. The medical cost of these common ailments is staggering: osteoporosis alone causes more than 1.5 million fractures each year with annual costs to the health system of approximately $14 billion. The human cost--in pain, disfigurement, restricted movement, and lost work--is incalculable. Today pioneering research is being done, and new drugs have become available to alleviate patients’suffering. Musculoskeletal Drug Therapy for Geriatric Patients offers detailed discussions of the newest drug treatments and recent findings on older medications. For example, many authorities agree that acetominophen should be frontline therapy of degenerative arthritis in the elderly, yet the most common adverse drug reaction of geriatric patients in long-term care is for NSAID gastropathy. This book suggests safer options, including the newest COX-2 inhibitors and disease-modifying anti-rheumatic drugs. Musculoskeletal Drug Therapy for Geriatric Patients offers clear strategies for the assessment and treatment of these painful, debilitating disorders in the elderly. Including tables and charts that comprehensively list test results, Musculoskeletal Drug Therapy for Geriatric Patients provides solid advice on the issues of medical management of these common diseases. This valuable book examines specific issues, including: the newest COX-2 inhibitors and how they work the evaluation, diagnosis, and management of osteoporosis osteoarthritis and its drug therapy a scholarly assessment of geriatric rheumatoid arthritis and its treatment. dosage, contraindications, and possible negative effects of various medications determining the need for chronic prophylactic therapy in patients with gout or hyperuricemia Although none of these musculoskeletal diseases can yet be cured, effective drug therapy can keep them in check. Musculoskeletal Drug Therapy for Geriatric Patients will help you give your patients the most powerful new treatments with the fewest side effects, thereby improving their quality of life.
Still considered the definitive work on medicinal herbs and their uses after two decades, the Handbook of Medicinal Herbs has undergone a long-anticipated revision. In the second edition, world-renowned ethnobotanist James A. Duke provides up-to-date data on over 800 of the world's most important medicinal plant species. The book contains mo
For 25 years, Rang and Dale’s Pharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide. Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at studentconsult.com. Consult this title on your favorite e-reader. Get the essential pharmacology information you need from one authoritative source with an outstanding global reputation for excellence. Progress confidently through all relevant aspects of pharmacology, beginning with a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs. Find important content quickly thanks to a color-coded layout that enables easy navigation and cross-referencing. Master difficult concepts with Key Points boxes, Clinical Uses boxes, and full-color illustrations throughout. Stay up to date with new information in the field, including an all-new chapter on drugs that affect the skin. Take advantage of new and unique features online, including 500+ chapter-specific multiple choice questions for immediate self-assessment. eBook version included! For the first time, you can access the entire book online or offline across all devices with the Student Consult eBook!
The true story of five talented young men in exile in the time of Hitler and Mao Tse-Tung. 'Altogether they knew five wars, three revolutions and - in the case of Ian Milner, accused in the Cold War of being a spy - a slander.' Regarded by one critic as 'the best book published in New Zealand in the last twenty years', this is a fascinating story based on letters, diaries and interviews in several countries. It is the story of a group of Rhodes scholars, five young men - James Bertram, Geoffrey Cox, Dan Davin, Ian Milner, John Mulgan - caught up in the turmoil of their times: Spain, Hitler's Germany, Greece and North Africa, Eastern Europe, China. They left New Zealand in the thirties for 'the dreaming spires' of Oxford. War intervened. Only one returned.
Obtain all the core knowledge in pain management you need from one of the most trusted resources in the field. The new edition of Practical Management of Pain gives you completely updated, multidisciplinary overview of every aspect of pain medicine, including evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. It is all the expert guidance necessary to offer your patients the best possible relief. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Access up-to-the-minute knowledge on all aspects of pain management, from general principles to specific management techniques, with contributions from renowned pain management experts. Understand and apply the latest developments in pain management with brand-new chapters covering disability assessment, central post-stroke pain, widespread chronic pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics).
Rang and Dale's Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. - Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines - Clear figures to aid understanding, including data figures as well as mechanistic diagrams, - Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts - Emphasis on therapeutic drugs to help apply theory to practice - Over 150 questions and 12 clinical cases to test your knowledge - New chapters on drugs and the eye and the pharmacological management of headache - Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. - A completely revised and updated chapter on lifestyle drugs - Recent advances in oxygen sensing and response to reduced oxygen tension - Expanded chapters on dementia and analgesic drugs
Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.
The verdicts have made headlines, but little is known about the inner workings of the court in which they were delivered. In Fifty Years of Justice, James Denham presents the fascinating history of the U.S. Middle District Court of Florida from its founding in 1962 to the present. Readers will discover the intricacies of rulings, the criminal defendants and civil litigants, and the dedicated officials—the unsung heroes—who keep the justice system running day to day. From desegregation to discrimination, espionage to the environment, trafficking to terrorism, and a host of cases in between, litigation in these courtrooms has shaped and shaken both state and nation.
Understanding the key components of the diagnosis, assessment and management of inflammatory arthritis patients is essential to improving patient care. This book aims to cover these areas. It places inflammatory arthritis into a historical context; deals with the epidemiology, pathology, clinical assessment and investigation of inflammatory arthritis patients and provides a comprehensive overview of currently available treatment options. It provides insight into stratified medicine, an area of emerging importance in the management of heterogeneous diseases like RA. Finally, it provides an overview of what treatments strategies are in development.
Geography and Geographers continues to be the most comprehensive and up-to-date overview of human geography available. It provides a survey of the major debates, key thinkers and schools of thought in the English-speaking world, setting them within the context of economic, social, cultural, political and intellectual changes. It is essential reading for all undergraduate geography students. It draws on a wide reading of the geographical literature and addresses the ways geography and its history are understood and the debates among geographers regarding what the discipline should study and how. This extensively updated seventh edition offers a thoroughly contemporary perspective on human geography for new and more experienced students alike.
The hope is that by measuring soluble, circulating markers, targets for cancer therapy can be identified with non-invasive procedures. To help attain that goal, Wu (pathology, U. of Utah-Salt Lake City) identifies and describes any circulating tumor markers he thinks might help. Annotation copyrighted by Book News, Inc., Portland, OR
Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Chief among its contents we find abstracts of land grants, court records, conveyances, births, deaths, marriages, wills, petitions, military records (including a list of North Carolina Officers and Soldiers of the Continental Line, 1775-1782), licenses, and oaths. The abstracts derive from records now located in the state archives and from the public records of the following present-day counties of the Old Albemarle region: Beaufort, Bertie, Camden, Chowan, Currituck, Dare, Gates, Halifax, Hyde, Martin, Northampton, Pasquotank, Perquimans, Tyrrell, and Washington, and the Virginia counties of Surry and Isle of Wight.
Beneath the wholesome image of Archer Daniels Midland lie some of the dirtiest practices in American business: price-fixing, bribery, and cover-ups. Unfolding like a legal thriller, Rats in the Grain portrays the crime and punishment of ADM during the largest white-collar criminal trial of the 1990s. James Lieber profiles the witnesses, the defense lawyers and federal prosecutors, the inner workings of the Justice Department's Antitrust Division, and the unpredictable mole Lieber had access to. "A detailed account of how an influential corporation can go rotten." -- The Cleveland Plain Dealer
THE STORY: In the words of Stanley Kauffmann, the play, ...which is a fantasy of the corruption of innocence, concerns a fourteen- or fifteen-year-old boy, well-dressed and well-spoken, who--when we meet him--has been sitting daily on a bench in front
Rang & Dale’s Pharmacology provides you with all the knowledge you need to get through your pharmacology course and beyond. Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson present a clear and accessible approach to the analysis of therapeutic agents at the cellular and molecular level through detailed diagrams, full-color illustrations, and pedagogical features. Find and cross-reference information quickly using a color-coded layout that makes navigation easy. Effectively understand and review key concepts through detailed diagrams and full-color illustrations that clarify even the most complex concepts. Reinforce your learning with key points boxes and clinical uses boxes that highlight crucial information and clinical applications. Apply current best practices and clinical applications through thoroughly updated and revised drug information. Stay current with the latest developments in the field thanks to major updates in chapters such as How Drugs Act; Amino Acid Transmitters; Analgesic Drugs; Antidepressant Drugs; and Drug Addiction, Dependence & Abuse. Tap into comprehensive content tailored to your courses with new and reorganized chapters on Host Defense; Inflammatory Mediators; Pharmacogenetics, Pharmacogenomics & Personalized Medicine; Hydroxytoptomine & The Pharmacy of Migraine; and Purines.
Published originally in 1981, the work at hand is an alphabetical listing of all free African-American heads of household listed in the five U.S. censuses for the State of New York taken between 1790 and 1830. Since it was during this 40-year period that the New York legislature passed a series of statutes resulting in the gradual emancipation of the state's slave population, the scope of this work documents the emergence of a completely free black population by 1830. In all, there are 15,000 references to freedmen, many of whom appear in more than one census.
Provides guidelines on how to prevent and alleviate the signs and symptoms of aging, introducing a variety of herbs, nutritional supplements, and diet tips to help cope with illnesses associated with aging.
Through 10 outstanding editions, Kelley & Firestein's Textbook of Rheumatology has provided authoritative, in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. The 11th Edition of this classic text continues this tradition of excellence, while keeping you abreast of recent advances in genetics and the microbiome, new therapies such as biologics and biosimilars, and other rapid changes in the field. It provides comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, in a user-friendly, full color reference. - Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes—including key data on therapeutic outcomes to better inform clinical decision making. - Includes new chapters on Innate Lymphoid Cells and Natural Killer Cells, Pathogenesis of Inflammasome Mediated Diseases, Bisphosphonates, Ultrasound Evaluation of the Musculoskeletal System, and Evaluation of Monoarticular and Polyarticular Arthritis. - Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs. - Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editor Dr. Gary Koretzky, specialist in immunology and rheumatology. - Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Get the core knowledge in pain medicine you need from one of the most trusted resources in the field. The new fourth edition guides you through every aspect of pain medicine with concise descriptions of evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. From commonly seen pain syndromes, including headaches, trunk pain, orofacial pain, back pain, and extremity pain...through specific pain management challenges such as postoperative pain, pain due to cancer, phantom pain, and pain in the management of AIDS patients...this popular text will equip you with the know-how you need to effectively manage even your most challenging cases. A practical, multidisciplinary approach to pain management makes key concepts and techniques easier to apply to everyday practice. Expert contributors provide the latest knowledge on all aspects of pain management, from general principles through to specific management techniques. Detailed discussions of the latest concepts and treatment plans help you provide the best possible outcomes for all your patients. Extensively updated chapters acquaint you with the most current trends and techniques in pain management. A new section on complications helps you avoid and manage potential pitfalls. A new editorial team ensures that you are getting the freshest, most clinically relevant information available today. New, full-color art clarifies key concepts and techniques.
Jess Willard, the "Pottawatomie Giant," won the heavyweight title in 1915 with his defeat of Jack Johnson, the first black heavyweight champion. At 6 feet, 6 inches and 240 pounds, Willard was considered unbeatable in his day. He nonetheless lost to Jack Dempsey in 1919 in one of the most brutally one-sided contests in fistic history. Willard later made an initially successful comeback but was defeated by Luis Firpo in 1923 and retired from the ring. He died in 1968, largely forgotten by the boxing public. Featuring photographs from the Willard family archives, this first full-length biography provides a detailed portrait of one of America's boxing greats.
Paddy Costello was a scholar, a soldier, a diplomat, a maverick, an exemplary father, a lover of good wine. But this fascinating biography also asks was he a spy? Auckland. Cambridge. Moscow. Paris. New Zealand’s 'most brilliant linguist and ablest foreign envoy'. The man who alerted the West to Soviet possession of the atom bomb. The first Allied diplomat to enter and report on the Nazi death camps at the end of the war. General Freyberg’s favourite Intelligence officer. This masterful biography explores the truth behind the rumours and reveals a fascinating man.
- NEW! Eight new chapters include the latest information on: - the human-animal bond - local and regional techniques - preventive and multimodal analgesia - energy modalities - acupuncture - physical examination with emphasis on isolating and locating pain - therapeutic goals - pain in laboratory animals - NEW! Completely updated drug information, with new agents, doseforms, and routes provides the most current pain management therapies for use in the clinical setting. - NEW! Expanded sections on the cat and exotics address the growing popularity of these pets by providing additional species-specific information.
**Selected for Doody's Core Titles® 2024 in Veterinary Medicine** Use the veterinarian's #1 reference on general pathology and the pathology of organ systems! Pathologic Basis of Veterinary Disease, 7th Edition helps you understand and diagnose diseases of domestic animals by using the latest scientific and medical research. Focusing on dogs, cats horses, cattle, sheep, goats, and pigs, this reference describes and vividly illustrates and explores the pathogeneses of animal diseases, how cells and tissues respond to injury, and the morphology (lesions) of this injury. New to this edition is basic coverage of tumor, inflammatory, and microbial cytology. Edited by veterinary pathologist James F. Zachary and a team of expert veterinary pathologists, this book includes access to an enhanced eBook with every new print purchase, featuring a fully searchable version of the entire text, an image collection, and much more – and available on a variety of devices. - Clear, up-to-date illustrations and explanations of the macroscopic (gross) and microscopic lesions resulting from diseases occurring in domestic animals - Complete coverage of both general pathology and the pathology of organ systems that includes the latest research, practice, and diagnostic information on disease mechanisms, pathogenesis, and lesions. - Clear explanations of disease mechanisms that describe cell, tissue, and organ system responses to injury and infection. - Easy-to-follow organization for each systemic disease chapter including a brief review of the study of diseases that occur in specific tissues, organs, and organ systems, with basic principles related to anatomy, structure, and function, followed by congenital and functional abnormalities and discussions of infectious disease responses, helping students apply principles to veterinary practice. - More than 2,100 full-color illustrations featuring color photographs, schematics, flow charts, and diagrammatic representations of disease processes as well as summary tables and boxes, making it easier to understand difficult concepts. - Content on cellular and organ system pathology updated throughout the book, with expanded coverage of genetics and disease. - Key Readings Index in each chapter with page numbers for key topics. - Essential Concept boxes in each General Pathology chapter break down complicated topics that are critical to understanding lesions and pathogeneses. - More than 20 recognized experts deliver the most relevant information for the practitioner, student, or individual preparing for the American College of Veterinary Pathologists' board examination. - An enhanced eBook is included with new print purchase, featuring the complete, fully searchable text plus an image collection; the text, tables, and boxes linked to the website that are cited throughout the book; ten new appendices that focus on veterinary diagnostic pathology, postmortem examination, interpretation of lesions, and more; plus an established appendix of photographic techniques used in veterinary diagnostic pathology.
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