The comprehensive history of yeast research. • Traces the growing understanding of yeasts and their role in the evolution of microbiology, biochemistry, cytology, and genetics. • Details how findings in yeast research were used to overcome complex problems and to develop currently accepted scientific concepts and methods. • Emphasizes experimental evidence, by reproducing many figures from the original researchers’ work as well as illustrations of the equipment they used. The book is enlivened with images of many of the scientists and offers accounts of notable incidents in the lives of some of them. • Serves as a resource for microbiology, biochemistry, or general biology students.
The heroism of the men in the Eleventh Battalion Georgia Light Artillery is a story that needs to be told." -Jimmy Carter, former president of the United States "Unique photographs and thorough individual war service record briefs make this book valuable as a research tool for personal, school, and public libraries alike." -Ben C. Sewell III, executive director, Sons of Confederate Veterans Beginning with Georgia's decision to secede from the union, author James L. Speicher chronicles the history of the little-known battalion that bravely fought for the Confederacy from 1861 to 1865. With more than eight hundred members serving at various points during the Civil War, most men in the unit, many of whom died on the battlefield, were from Sumter County, Georgia. Speicher details the horrific conditions they faced during their clashes, including the battle at Dranesville, which resulted in the most bloodshed experienced by the unit. Diary entries and personal letters, provided by descendants of the soldiers, illustrate daily life during the war. Rather than analyze the underlying causes of the war, the author focuses on the men who endured it, the men of the Sumter Flying Artillery. Speicher's scope includes Allen Sherrod Cutts, the battery's first commander and most prominent member. This remarkable man received personal congratulations from Gen. Robert E. Lee for leading his battalion to safety during the deadly battle of South Mountain in 1862. Highlights include pictures of the men before they left for battle, portraits of the Confederates in uniform, and images of the unit's flag. Appendixes provide a full roster listing each member's name, rank, and enlistment date, along with a section detailing the organization of the unit and the specific cannon used by the Sumter Battalion. With maps illustrating the position of the battery during specific battles, such as Gettysburg, and information on each officer, this book is an asset to genealogists and students of the Civil War. ABOUT THE AUTHOR James L. Speicher served in the U.S. Army for thirty years. He is a life member of the Sons of Confederate Veterans and Missouri's Civil War Heritage Foundation, among other organizations. After earning his B.A. in history from the Citadel, he obtained an A.A.S. in law enforcement from Oakland Community College and advanced degrees from Wayne State University and Webster University. Speicher resides in Shawnee, Kansas, with his wife.
The mid-twentieth century witnessed nations across Africa fighting for their independence from colonial forces. By examining black Americans' attitudes toward and responses to these liberation struggles, James Meriwether probes the shifting meaning of Africa in the intellectual, political, and social lives of African Americans. Paying particular attention to such important figures and organizations as W. E. B. Du Bois, Martin Luther King Jr., and the NAACP, Meriwether incisively utilizes the black press, personal correspondence, and oral histories to render a remarkably nuanced and diverse portrait of African American opinion. Meriwether builds the book around seminal episodes in modern African history, including nonviolent protests against apartheid in South Africa, the Mau Mau war in Kenya, Ghana's drive for independence under Kwame Nkrumah, and Patrice Lumumba's murder in the Congo. Viewing these events within the context of their own changing lives, especially in regard to the U.S. civil rights struggle, African Americans have continually reconsidered their relationship to contemporary Africa and vigorously debated how best to translate their concerns into action in the international arena. Grounded in black Americans' encounters with Africa, this transnational history sits astride the leading issues of the twentieth century: race, civil rights, anticolonialism, and the intersections of domestic race relations and U.S. foreign relations.
Mississippi: The Closed Society is a book about an insurrection in modern America, more particularly, about the social and historical background of that insurrection. It is written by a Mississippian who is a historian, and who, on September 30, 1962, witnessed the long night of riot that exploded on the campus of the University of Mississippi at Oxford, when students, and, later, adults with no connection with the University, attacked United States marshals sent to the campus to protect James H. Meredith, the first African American to attend Ole Miss. In the first part of Mississippi: The Closed Society, Silver describes how the state's commitment to the doctrine of white supremacy led to a situation in which the Mississippian found that continued intransigence (and possibly violence) was the only course offered to him. In these chapters the author speaks in the more formal measures of the historian. In the second part of the book, “Some Letters from the Closed Society,” he reproduces (among other correspondence and memoranda) a series of his letters to friends and family—and critics—in the days and weeks after the insurrection. Here he reveals himself more personally and forcefully. In both parts of the book are disclosed the mind and heart of the Mississippian who is as haunted as William Faulkner was by the moral chaos of his native land.
Using a unique approach, the author explores the disaster through the lives of fifty people linked to the sinking, from all walks of life and geographical regions. To have sailed on ‘the voyage of the century’ aboard White Star Line’s RMS Titanic – described at the time as ‘a floating palace’ – was like being one of the first passengers to fly on Concorde. On 10 April 1912, people from all walks of life began embarking on Titanic, then the largest ship afloat, for what was to be the trip of a lifetime on the ship’s maiden voyage across the north Atlantic. Many were looking forward to starting new lives in the United States. However, just before midnight on Sunday, 14 April 1912, Titanic’s crew began to send out distress signals stating, ‘We have struck an iceberg.' The liner had been steaming at speed when it collided with an enormous iceberg which stripped off her bilge under the waterline for more than 100 yards, opened up five of the front compartments and flooded the coal bunker servicing one of the boilers. The damage was fatal, and some three hours after the disaster began to unfold the last visible part of Titanic slipped beneath the waves. There were only sixteen lifeboats and four collapsible dinghies – which was completely insufficient for the number of passengers making the crossing. As a consequence, more than 1,500 passengers and crew died: two out of every three people onboard perished. Much has been written about the Titanic disaster, and it has been the subject matter for several films. The author is well-known for his depth of research and his attention to detail, and in a new style of format, he has selected fifty people involved in the disaster, and by using their specific eyewitness accounts he has managed to make the confusing situation much clearer, making it possible for the reader to experience the dreadful events as they unfolded. The book also includes biographical tributes to the fifty people, who came from all walks of life and geographical regions, telling who they were, their experiences during the disaster, and what happened to those who were fortunate enough to survive.
How do media find an audience when there is an endless supply of content but a limited supply of public attention? Feature films, television shows, homemade videos, tweets, blogs, and breaking news: digital media offer an always-accessible, apparently inexhaustible supply of entertainment and information. Although choices seems endless, public attention is not. How do digital media find the audiences they need in an era of infinite choice? In The Marketplace of Attention, James Webster explains how audiences take shape in the digital age. Webster describes the factors that create audiences, including the preferences and habits of media users, the role of social networks, the resources and strategies of media providers, and the growing impact of media measures—from ratings to user recommendations. He incorporates these factors into one comprehensive framework: the marketplace of attention. In doing so, he shows that the marketplace works in ways that belie our greatest hopes and fears about digital media. Some observers claim that digital media empower a new participatory culture; others fear that digital media encourage users to retreat to isolated enclaves. Webster shows that public attention is at once diverse and concentrated—that users move across a variety of outlets, producing high levels of audience overlap. So although audiences are fragmented in ways that would astonish midcentury broadcasting executives, Webster argues that this doesn't signal polarization. He questions whether our preferences are immune from media influence, and he describes how our encounters with media might change our tastes. In the digital era's marketplace of attention, Webster claims, we typically encounter ideas that cut across our predispositions. In the process, we will remake the marketplace of ideas and reshape the twenty-first century public sphere.
The Buffalo Trace area - Mason, Bracken, Fleming, Robertson & Lewis counties in northeastern Kentucky, and Adams, Brown & Clermont counties in southwestern Ohio - occupies a unique place in Civil War history. On the borders of North & South, East and West, Slave & Free, Union & Confederate - emotions ran high in a conflict that became known as "The Brothers War," as families and communities chose sides. As we observe the 150th anniversary of the end of this armed conflict, it makes sense to reflect on how our ancestors thought and acted during this crucial time in our national history. Their involvement might surprise you. Over 650 contemporary articles from local and national newspapers illustrate this local history, and serve to remind us of our ancestors opinions, choices and sacrifices. 356 pages.
Advocates for economic development often call for greater transparency. But what does transparency really mean? What are its consequences? This breakthrough book demonstrates how information impacts major political phenomena, including mass protest, the survival of dictatorships, democratic stability, as well as economic performance. The book introduces a new measure of a specific facet of transparency: the dissemination of economic data. Analysis shows that democracies make economic data more available than do similarly developed autocracies. Transparency attracts investment and makes democracies more resilient to breakdown. But transparency has a dubious consequence under autocracy: political instability. Mass-unrest becomes more likely, and transparency can facilitate democratic transition - but most often a new despotic regime displaces the old. Autocratic leaders may also turn these threats to their advantage, using the risk of mass-unrest that transparency portends to unify the ruling elite. Policy-makers must recognize the trade-offs transparency entails.
James Stewart Lockhart called it "the great difference". Returned from an inspection tour of the newly leased extension to Hong Kong territory in August 1898, Lockhart, a senior Hong Kong colonial official, had used this phrase to describe the gulf between the New Territories and its people and the existing British colony of Hong Kong and its inhabitants. In this volume, James Hayes argues that this "the great difference" led the colonial government to administer the New Territories and its people differently from the old urban area from the outset, resulting in repercussions that affect present-day Hong Kong. The study covers the whole period of the Lease, with all its crowded events and dramatic changes, as they affected the native inhabitants and their relationship with the government and, over time, the many times larger new urban population. James Hayes (PhD Lond; HonDLitt, HK) is a scholar of the Hong Kong region and its people. He worked in the New Territories for almost half his thirty-two years of government service, and was Regional Secretary in charge of district administration there in 1985-87. His publications include Friends and Teachers: Hong Kong and Its People 1953-87 (Hong Kong University Press, 1996) and South China Village Culture (2001).
Sites of gruesome murders, stories of killings, frauds, jewel thefts and treachery are all part of Mad Frankie Fraser's grand tour of Britain's criminal underworld. As one of the most notorious gangsters of the 20th Century, he is perfectly placed to give us the lowdown on crimes from up and down the country, plus his take on crimes he was personally involved in and cases as yet unsolved. Written with crime author James Morton, this is the definitive guide to Britain's many lives of crime.
Rang and Dale's Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. - Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines - Clear figures to aid understanding, including data figures as well as mechanistic diagrams, - Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts - Emphasis on therapeutic drugs to help apply theory to practice - Over 150 questions and 12 clinical cases to test your knowledge - New chapters on drugs and the eye and the pharmacological management of headache - Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. - A completely revised and updated chapter on lifestyle drugs - Recent advances in oxygen sensing and response to reduced oxygen tension - Expanded chapters on dementia and analgesic drugs
This book evaluates the newest efforts and initiative aimed at preventing burglary, discusses their merits and short- comings, and suggests how improvements might be incorporated in burglary prevention programs.
An authoritative, self-contained overview of time series analysis for students and researchers The past decade has brought dramatic changes in the way that researchers analyze economic and financial time series. This textbook synthesizes these advances and makes them accessible to first-year graduate students. James Hamilton provides comprehensive treatments of important innovations such as vector autoregressions, generalized method of moments, the economic and statistical consequences of unit roots, time-varying variances, and nonlinear time series models. In addition, he presents basic tools for analyzing dynamic systems—including linear representations, autocovariance generating functions, spectral analysis, and the Kalman filter—in a way that integrates economic theory with the practical difficulties of analyzing and interpreting real-world data. Time Series Analysis fills an important need for a textbook that integrates economic theory, econometrics, and new results. This invaluable book starts from first principles and should be readily accessible to any beginning graduate student, while it is also intended to serve as a reference book for researchers.
World-renowned coverage of today's pharmacology at your fingertips - Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more. - Includes access to unique features, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment. - Features a color-coded layout for faster navigation and cross-referencing. - Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout.
Thoroughly updated for its Second Edition, Non-Hodgkin Lymphomas is the definitive textbook on the biology, diagnosis, staging, and treatment of all forms of non-Hodgkin lymphomas. With backgrounds in medical and radiation oncology, molecular biology, and pathology, the editors and contributors provide an international, multidisciplinary approach to the topic. This edition is the first text using the new World Health Organization classification of non-Hodgkin lymphomas. The book offers complete coverage of the most current techniques for diagnosis, staging, and treatment, the approach to specific types of lymphoma, and special problems common to the management of patients with these disorders.
Lyotard and the Political is the first book to consider the full range of the political thought of the French philosopher François Lyotard and its broader implications for an understanding of the political. James Williams clearly and carefully traces the development of Lyotard's thought from his early Marxist essays on the Algerian struggle for independence to his break with the thought of Marx and Freud. This is compared with Lyotard's later, highly influental writings on the politics of desire and his attempts to base a postmodern political discourse on the sublime. An indispensable work for all who are interested in modern continental philosophy, Lyotard and the Political offers the first systematic analysis of the political dimension of the work of one of the most controversial and influential philosophers of the twentieth century. Also available in this series: Lacan and the Political Pb: 0-415-17187-3: £12.99 Heidegger and the Political Pb:0-415-13064-6: £12.99 Derrida and the Political Pb: 0-415-10967-1: £13.99 Nietzche and the Political Pb: 0-41510069-0: £12.99 Foucault and the Political Pb: 0-415-10066-6: £12.99
The must-have book for sports lovers! For sport fans everywhere, the 2014 edition of Year in Sports features an exciting new cover, full-color action photographs throughout, completely updated facts and stats, brand-new interior design, new chapter openers, and new Top 10 moments from lists from the past year in sports. With info about all of the top athletes, championships, and legends from the major and secondary sports. If you love sports, then you have to have this book.
It is well known that the numbers of organs that become available each year for transplantation fall far short of the numbers that are actually required. In this boldly argued book James Stacey Taylor contends that, given both this shortage and the desperate poverty that some people endure, it is morally imperative that the current methods of organ procurement be supplemented by a legal, regulated market for human transplant organs purchased from live vendors. Taylor pays particular attention to outlining the implications that recognizing the moral legitimacy of these market transactions in human body parts and reproductive capacities have for public policy.
The thoroughly updated Fifth Edition of Pediatric Neuroimaging is a highly illustrated text-reference that describes and illustrates the full range of pediatric disorders diagnosable by modern neuroimaging. Covering the diagnosis of brain, spinal, and head and neck disorders in the pediatric patient, the text is rooted in the principle that the proper interpretation of studies requires the acquisition of high-quality images and an understanding of the basic concepts of neuroembryology, normal development, and pathophysiology. Much coverage is given to the disorders seen in everyday practice. The emphasis is on CT and MRI, which are the optimal imaging modalities in children. The first two chapters describe useful imaging techniques in this patient population and the imaging manifestations of normal development, to distinguish that from manifestations of disease. The final ten chapters of the book are divided by groups of diseases, with numerous drawings and images that illuminate the underlying pathologic and embryologic/genetic bases of each disorder. The goal is provide a basic approach to groups of diseases, then offer detailed information about the clinical manifestations, underlying biochemistry, molecular biology, genetics and/or pathology of specific disorders. The book incorporates the essential concepts for obtaining good images and understanding normal development, which helps the reader to distinguish normal developmental changes from disease
The Digital Hand, Volume 2, is a historical survey of how computers and telecommunications have been deployed in over a dozen industries in the financial, telecommunications, media and entertainment sectors over the past half century. It is past of a sweeping three-volume description of how management in some forty industries embraced the computer and changed the American economy. Computers have fundamentally changed the nature of work in America. However it is difficult to grasp the full extent of these changes and their implications for the future of business. To begin the long process of understanding the effects of computing in American business, we need to know the history of how computers were first used, by whom and why. In this, the second volume of The Digital Hand, James W. Cortada combines detailed analysis with narrative history to provide a broad overview of computing's and telecomunications' role in over a dozen industries, ranging from Old Economy sectors like finance and publishing to New Economy sectors like digital photography and video games. He also devotes considerable attention to the rapidly changing media and entertainment industries which are now some of the most technologically advanced in the American economy. Beginning in 1950, when commercial applications of digital technology began to appear, Cortada examines the ways different industries adopted new technologies, as well as the ways their innovative applications influenced other industries and the US economy as a whole. He builds on the surveys presented in the first volume of the series, which examined sixteen manufacturing, process, transportation, wholesale and retail industries. In addition to this account, of computers' impact on industries, Cortada also demonstrates how industries themselves influenced the nature of digital technology. Managers, historians and others interested in the history of modern business will appreciate this historical analysis of digital technology's many roles and future possibilities in an wide array of industries. The Digital Hand provides a detailed picture of what the infrastructure of the Information Age really looks like and how we got there.
Rpresentative agent models have become a predominant means of studying the macroeconomy in modern economics without there being much discussion in the literature about their propriety or usefulness. This volume evaluates the use of these models in macroeconomics, examining the justifications for their use and concluding that representative agent models are neither a proper nor a particularly useful means of studying aggregate behaviour.
Health Care Operations Management: A Systems Perspective, Second Edition provides comprehensive and practical coverage of all aspects of operations management specific to the healthcare industry. It covers everything from hospital finances to project management, patient flows, performance management, process improvement, and supply chain management. This is an ideal text for university courses in healthcare management at all levels. It is also an excellent professional reference for healthcare administrators, clinical support managers, and supply chain professionals. The Second Edition has been thoroughly updated with the most recent data, statistics, and references. It also offers expanded coverage of quality, financial, and systems management, as well as a new chapter entitled "Operational Metrics in Health Care Organization".
A book of heroic dimensions, this is the first full-length biography of one of the greatest artists of the twentieth century—a man as fascinating, difficult, and compelling as the paintings he produced. Drawing on exclusive access to Mark Rothko's personal papers and over one hundred interviews with artists, patrons, and dealers, James Breslin tells the story of a life in art—the personal costs and professional triumphs, the convergence of genius and ego, the clash of culture and commerce. Breslin offers us not only an enticing look at Rothko as a person, but delivers a lush, in-depth portrait of the New York art scene of the 1930s, ’40s, and ’50s—the world of Abstract Expressionism, of Pollock, Rothko, de Kooning, and Klein, which would influence artists for generations to come. "In Breslin, Rothko has the ideal biographer—thorough but never tedious, a good storyteller with an ear for the spoken word, fond but not fawning, and possessed of a most rare ability to comment on non-representational art without sounding preposterous."—Robert Kiely, Boston Book Review "Breslin impressively recreates Mark Rothko's troubled nature, his tormented life, and his disturbing canvases. . . . The artist's paintings become almost tangible within Breslin's pages, and Rothko himself emerges as an alarming physical force."—Robert Warde, Hungry Mind Review "This remains beyond question the finest biography so far devoted to an artist of the New York School."-Arthur C. Danto, Boston Sunday Globe "Clearly written, full of intelligent insights, and thorough."—Hayden Herrera, Art in America "Breslin spent seven years working on this book, and he has definitely done his homework."-Nancy M. Barnes, Boston Phoenix "He's made the tragedy of his subject's life the more poignant."—Eric Gibson, The New Criterion "Mr. Breslin's book is, in my opinion, the best life of an American painter that has yet been written . . . a biographical classic. It is painstakingly researched, fluently written and unfailingly intelligent in tracing the tragic course of its subject's tormented character."—Hilton Kramer, New York Times Book Review, front page review James E. B. Breslin (1936-1996) was professor of English at the University of California, Berkeley, and author of From Modern to Contemporary: American Poetry, 1945-1965 and William Carlos Williams: An American Artist.
Rang & Dale’s Pharmacology provides you with all the knowledge you need to get through your pharmacology course and beyond. Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson present a clear and accessible approach to the analysis of therapeutic agents at the cellular and molecular level through detailed diagrams, full-color illustrations, and pedagogical features. Find and cross-reference information quickly using a color-coded layout that makes navigation easy. Effectively understand and review key concepts through detailed diagrams and full-color illustrations that clarify even the most complex concepts. Reinforce your learning with key points boxes and clinical uses boxes that highlight crucial information and clinical applications. Apply current best practices and clinical applications through thoroughly updated and revised drug information. Stay current with the latest developments in the field thanks to major updates in chapters such as How Drugs Act; Amino Acid Transmitters; Analgesic Drugs; Antidepressant Drugs; and Drug Addiction, Dependence & Abuse. Tap into comprehensive content tailored to your courses with new and reorganized chapters on Host Defense; Inflammatory Mediators; Pharmacogenetics, Pharmacogenomics & Personalized Medicine; Hydroxytoptomine & The Pharmacy of Migraine; and Purines.
Most research on two-party elections has considered the outcome as a single, dichotomous event: either one or the other party wins. In this groundbreaking book, James Fowler and Oleg Smirnov investigate not just who wins, but by how much, and they marshal compelling evidence that mandates-in the form of margin of victory-matter. Using theoretical models, computer simulation, carefully designed experiments, and empirical data, the authors show that after an election the policy positions of both parties move in the direction preferred by the winning party-and they move even more if the victory is large. In addition, Fowler and Smirnov not only show that the divergence between the policy positions of the parties is greatest when the previous election was close, but also that policy positions are further influenced by electoral volatility and ideological polarization. This pioneering book will be of particular interest to political scientists, game theoreticians, and other scholars who study voting behavior and its short-term and long-range effects on public policy.
Power Without Responsibility is a classic introduction to the history, sociology, theory and politics of the media in Britain. It is an essential guide, both for students and teachers of media and communication studies, and for all those involved in the production and consumption of the media. The new edition has been substantially revised to bring it right up-to-date with developments in the media industry, new media technologies and changes in the political and academic debates surrounding media policy. In this new edition, the authors consider: * whether we are on the threshold of a new communications revolution * the role of global media empires * the rise of video, cable and satellite * the global information society and contradictions in media policy * the BBC and broadcasting at the end of the 1990s * the evolving relationship of the press and the Conservative party. Assessing the press and broadcasting at a time of radical change, the authors suggest a manifesto for media reform.
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