This symposium was dedicated to science opportunities with the VLT. All major areas of astronomical research were discussed in the plenary sessions, ranging from where we stand in cosmology to the new frontiers in the solar system. The workshops published in this volume focussed on different ways of finding clusters of galaxies at high redshift, on gravitational lensing by distant compact clusters, on the use of stellar populations as distance, age or abundance indicators, and on the extraordinary progress made in the discovery of extrasolar planets. This book affords a glimpse of what will be at the center of astrophysical research in the forthcoming decade. It is addressed to researchers and graduate students.
Charlotte Smith's early sonnets established the genre as a Romantic form; her novels advanced sensibility beyond its reliance on emotional facility; and her blank verse initiated one of the most familiar of Romantic verse forms. This volume draws together the best of current scholarship.
Why have cesarean sections become so commonplace in the United States? Between 1965 and 1987, the cesarean section rate in the United States rose precipitously—from 4.5 percent to 25 percent of births. By 2009, one in three births was by cesarean, a far higher number than the 5–10% rate that the World Health Organization suggests is optimal. While physicians largely avoided cesareans through the mid-twentieth century, by the early twenty-first century, cesarean section was the most commonly performed surgery in the country. Although the procedure can be lifesaving, how—and why—did it become so ubiquitous? Cesarean Section is the first book to chronicle this history. In exploring the creation of the complex social, cultural, economic, and medical factors leading to the surgery's increase, Jacqueline H. Wolf describes obstetricians' reliance on assorted medical technologies that weakened the skills they had traditionally employed to foster vaginal birth. She also reflects on an unsettling malpractice climate—prompted in part by a raft of dubious diagnoses—that helped to legitimize "defensive medicine," and a health care system that ensured cesarean birth would be more lucrative than vaginal birth. In exaggerating the risks of vaginal birth, doctors and patients alike came to view cesareans as normal and, increasingly, as essential. Sweeping change in women's lives beginning in the 1970s cemented this markedly different approach to childbirth. Wolf examines the public health effects of a high cesarean rate and explains how the language of reproductive choice has been used to discourage debate about cesareans and the risks associated with the surgery. Drawing on data from nineteenth- and early twentieth-century obstetric logs to better represent the experience of cesarean surgery for women of all classes and races, as well as interviews with obstetricians who have performed cesareans and women who have given birth by cesarean, Cesarean Section is the definitive history of the use of this surgical procedure and its effects on women's and children's health in the United States.
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.
Too often lost in our understanding of the American Cold War crisis, with its nuclear brinkmanship and global political chess game, is the simultaneous crisis on the nation's racial front. Reckoning Day is the first book to examine the relationship of African Americans to the atom bomb in postwar America. It tells the wide-ranging story of African Americans' response to the atomic threat in the postwar period. It examines the anti-nuclear writing and activism of major figures such as W.E.B. Du Bois, Dr. Martin Luther King Jr., and Lorraine Hansberry as well as the placement (or absence) of black characters in white-authored doomsday fiction and nonfiction. Author Jacqueline Foertsch analyzes the work of African American thinkers, activists, writers, journalists, filmmakers, and musical performers in the "atomic" decades of 1945 to 1965 and beyond. Her book tells the dynamic story of commitment and interdependence, as these major figures spoke with force and eloquence for nuclear disarmament, just as they argued unstintingly for racial equality on numerous other occasions. Foertsch also examines the location of African American characters in novels, science fiction, and survivalist nonfiction such as government-sponsored forecasts regarding post-nuclear survival. In these, black characters are often displaced or absented entirely: in doomsday narratives they are excluded from executive decision-making and the stories' often triumphant conclusions; in the nonfiction, they are rarely envisioned amongst the "typical American" survivors charged with rebuilding US society. Throughout Reckoning Day, issues of placement and positioning provide the conceptual framework: abandoned at "ground zero" (America's inner cities) during the height of the atomic threat, African Americans were figured in white-authored survival fiction as compliant servants aiding white victory over atomic adversity, while as historical figures they were often perceived as "elsewhere" (indifferent) to the atomic threat. In fact, African Americans' "position" on the bomb was rarely one of silence or indifference. Ranging from appreciation to disdain to vigorous opposition, atomic-era African Americans developed diverse and meaningful positions on the bomb and made essential contributions to a remarkably American dialogue.
Machine Learning for Drug Discovery is designed to suit the needs of graduate students, advanced undergraduates, chemists or biologists otherwise new to this research domain with minimal previous exposure to Machine Learning (ML) methods, or computational scientists with minimal exposure to medicinal chemistry. The e-book covers basic algorithmic theory, data representation methods, and generative modeling at a high level. The authors spotlight antibiotic discovery as a case study in ML for drug development and discuss diverse applications in drug-likeness prediction, antimicrobial resistance, and areas for future inquiry. For a more dynamic learning experience, open-source code demonstrations in Python are included.
An essential introductory textbook that guides students through 300 years of American plays, as well as their remarkable engagement with texts from across the Atlantic. Divided into seven historical periods, Jacqueline Foertsch offers unique overviews of 38 American plays and their reception, from Robert Hunter's Androboros (c.1714) to Lin-Manuel Miranda's Hamilton (2015). Each historical section begins with an overseas play that proved influential to American playwrights in that period, demonstrating to students an astonishing dialogue taking place across the Atlantic. This is an ideal core text for modules on American Drama – or a supplementary text for broader modules on American Literature – which may be offered at the upper levels of an undergraduate literature, drama, theatre studies or American studies degree. In addition it is a crucial resource for students who may be studying American drama as part of a taught postgraduate degree in literature, drama or American studies.
The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.
The story of the Peterloo massacre, a defining moment in the history of British democracy, told with passion and authority. 'Excellent' Zadie Smith 'Fast-paced and full of fascinating detail' Tim Clayton 'A superb account of one of the defining moments in modern British history' Tristram Hunt 'Peterloo is one of the greatest scandals of British political history... Riding tells this tragic story with mesmerising skill' John Bew On a hot late summer's day, a crowd of 60,000 gathered in St Peter's Field. They came from all over Lancashire – ordinary working-class men, women and children – walking to the sound of hymns and folk songs, wearing their best clothes and holding silk banners aloft. Their mood was happy, their purpose wholly serious: to demand fundamental reform of a corrupt electoral system. By the end of the day fifteen people, including two women and a child, were dead or dying and 650 injured, hacked down by drunken yeomanry after local magistrates panicked at the size of the crowd. Four years after defeating the 'tyrant' Bonaparte at Waterloo, the British state had turned its forces against its own people as they peaceably exercised their time-honoured liberties. As well as describing the events of 16 August in shattering detail, Jacqueline Riding evokes the febrile state of England in the late 1810s, paints a memorable portrait of the reform movement and its charismatic leaders, and assesses the political legacy of the massacre to the present day. As fast-paced and powerful as it is rigorously researched, Peterloo: The Story of the Manchester Massacre adds significantly to our understanding of a tragic staging-post on Britain's journey to full democracy.
This book's objective is to provide a focused overview (morphological, biochemical, and functional) of brain development, to exemplify the role of lipids in the important developmental events, and to develop the concepts explaining why physiological changes in brain lipid composition potentially alter these events.
Best Interests of the Student presents both a theoretical model for guiding educators as they confront legal and ethical dilemmas in their schools, as well as highly accessible and annotated court cases for exploration. Stefkovich introduces an ethical decision-making model that focuses on strategies for determining what actions are in the "best interests of the student," and demonstrates the application of this theoretical model for examining legal and ethical dimensions of court cases. Discussion questions at the end of each case encourage readers to examine issues from differing viewpoints, helping them to become more self-reflective school leaders who can effectively address legal dilemmas in their own contexts. This important text is a valuable resource for both aspiring and practicing school administrators and leaders. This thoroughly revised edition features: An entirely new chapter focusing on issues surrounding technology, specifically bullying, harassment, and "sexting" 13 new legal cases to reflect recent developments in school law, including issues of free speech, teacher accountability, and school policies A continued focus on preparing leaders to meet the Interstate School Leaders Licensure Consortium (ISLLC) ethics standard
With over 500 hand-picked titles, Healing Stories recommends carefully selected books essential for any adult looking to help children cope with their growing pains through reading. Annotated with helpful commentary, these titles cover everything from kids' everyday trials (losing baby teeth, starting school, having a bad day) to more emotionally stressful events (death of a pet, moving, illness), giving adults all the information they need to choose the right books. Also features useful tips to make reading fun and helpful for both adults and children. For more information, visit the Healing Stories Web site.
This book provides a systematic exploration of family literacy, including its historic origins, theoretical expansion, practical applications within the field, and focused topics within family literacy. Grounded in sociocultural approaches to learning and literacy, the book covers research on how families use literacy in their daily lives as well as different models of family literacy programs and interventions that provide opportunities for parent-child literacy interactions and that support the needs of children and parents as adult learners. Chapters discuss key topics, including the roles of race, ethnicity, culture, and social class in family literacy; digital family literacies; family-school relationships and parental engagement in schools; fathers’ involvement in family literacy; accountability and employment; and more. Throughout the book, Lynch and Prins share evidence-based literacy practices and highlight examples of successful family literacy programs. Acknowledging lingering concerns, challenges, and critiques of family literacy, the book also offers recommendations for research, policy, and practice. Accessible and thorough, this book comprehensively addresses family literacies and is relevant for researchers, scholars, graduate students, and instructors and practitioners in language and literacy programs.
The joy for me is that this is my anthology, and I love every single poem in this book.' Jacqueline Wilson This is a gorgeous, stunningly produced collection of classic and modern poems that girls will turn to again and again throughout their lives. Jacqueline has taken great delight in selecting and arranging her favourite poems for this book, and you can hear her voice in the beautiful poems she has chosen, making it a truly personal collection. There are poems that will make you smile, laugh, frown and cry, and poems that will stay with you for the rest of your life.
Best known as the woman who “ran MGM,” Ida R. Koverman (1876–1954) served as talent scout, mentor, executive secretary, and confidant to American movie mogul Louis B. Mayer for twenty-five years. She Damn Near Ran the Studio: The Extraordinary Lives of Ida R. Koverman is the first full account of Koverman’s life and the true story of how she became a formidable politico and a creative powerhouse during Hollywood’s Golden Era. For nearly a century, Koverman’s legacy has largely rested on a mythical narrative while her more fascinating true-life story has remained an enduring mystery—until now. This story begins with Koverman’s early years in Ohio and the sensational national scandal that forced her escape to New York where she created a new identity and became a leader among a community of women. Her second incarnation came in California where she established herself as a hardcore political operative challenging the state’s progressive impulse. During the Roaring Twenties, she was a key architect of the Southland’s conservative female-centric partisan network that refashioned the course of state and national politics and put Herbert Hoover in the White House. As “the political boss of Los Angeles County,” she was the premiere matchmaker in the courtship between Hollywood and national partisan politics, which, as Mayer’s executive secretary, was epitomized by her third incarnation as “one of the most formidable women in Hollywood,” whose unparalleled power emanated from her unique perch inside the executive suite of Metro-Goldwyn-Mayer. Free to adapt her managerial skills and political know-how on behalf of the studio, she quickly drew upon her artistic sensibilities as a talent scout, expanding MGM’s catalog of stars and her own influence on American popular culture. Recognized as “one of the invisible power centers in both MGM and the city of Los Angeles,” she nurtured the city’s burgeoning performing arts by fostering music and musicians and the public financing of them. As the “lioness” of MGM royalty, Ida Koverman was not just a naturalized citizen of the Hollywood kingdom; at times during her long reign, she “damn near ran the studio.”
The place of childhood in popular culture is one that invites new readings both on childhood itself, but also on approaches to studying childhood. Discussing different methods of researching children's popular culture, they argue that the interplay of the age of the players, the status of their popular culture, the transience of the objects, and indeed the ephemerality - and long lastingness - of childhood, all contribute to what could be regarded as a particularized space for childhood studies - and one that challenges many of the conventions of "doing research" involving children.
Decolonizing Data yields valuable insights into the decolonization of research methods by addressing and examining health inequalities from an anti-racist and anti-oppressive standpoint.
This publication characterizes the environmental burden of disease in the United Arab Emirates (UAE), measured by the excess number of deaths and illnesses in the population due to exposure to environmental hazards. The robust methods used in this risk analysis can be applied to any country or region. This publication documents the systematic, multi-step process used to identify environmental priorities and the detailed methods used to quantify the disease burden attributable to each risk. Based on the results of the burden of disease assessment, the publication summarizes the subsequent steps that are recommended to further reduce the burden of disease resulting from various environmental risk factors. Authors and Contributors This book represents the synthesis of research carried out by a large, interdisciplinary team from several institutions and multiple nations between June 2008 and June 2011.The lead authors are responsible for weaving together the pieces prepared by the team.Nonetheless, this book would not have been possible without major contributions from each team member.The list below shows contributors to each chapter.Following this list are biographies of all of the authors and contributors. Lead Authors Jacqueline MacDonald Gibson, Frederic J. P. Launay, Jens T. W. Thomsen, Angela Brammer, Christopher Davidson Additional Contributors (by Chapter) Chapter 2: Prioritizing Environmental Risks to Health Henry H. Willis, Aimee Curtright, Gary Cecchine, Zeinab S. Farah,Sandra A. Geschwind, Jianhui Hu, Ying Li, Melinda Moore, Sarah Olmstead, Hanine Salem, Regina A. Shih, J. Jason West Chapter 3: Assessing the Environmental Burden of Disease:Method Overview Tiina Folley, Elizabeth S. Harder, Mejs Hasan Chapter 4: Burden of Disease from Outdoor Air Pollution Ying Li, Gavino Puggioni, Prahlad Jat, Mejs Hasan, Marc Serre, Kenneth G. Sexton, J. Jason West, Saravanan Arunachalam, Uma Shankar, William Vizuete, Mohammed Zuber Farooqui Chapter 5: Burden of Disease from Indoor Air Pollution Chris B. Trent Chapter 6: Burden of Disease from Occupational Exposures Tiina Folley, Leena A. Nylander-French Chapter 7: Burden of Disease from Climate Change Richard N. L. Andrews, Leslie Chinery, Elizabeth S. Harder, J. Jason West Chapter 8: Burden of Disease from Drinking Water Contamination Gregory W. Characklis, Joseph N. LoBuglio Chapter 9: Burden of Disease from Coastal Water Pollution Gregory W. Characklis, Leigh-Anne H. Krometis, Joseph N. LoBuglio Chapter 10: Burden of Disease from Soil and Groundwater Contamination Chidsanuphong Chart-asa, Stephanie Soucheray-Grell Chapter 11: Burden of Disease from Produce and Seafood Contamination Leigh-Anne H. Krometis, Leslie Chinery
The result of years of work by scholars from all over the world, The UNESCO General History of Africa reflects how the different peoples of Africa view their civilizations and shows the historical relationships between the various parts of the continent. Historical connections with other continents demonstrate Africa's contribution to the development of human civilization. Each volume is lavishly illustrated and contains a comprehensive bibliography.
Emily Briggs is transformed into the Bride from Hell when her mother gets a little too involved with her wedding plans, a gorgeous blonde begins stalking their Tribeca loft, and she becomes attracted to the one man who will listen to her tales of woe--artist J3 Hopper. Reprint.
In this witty historical fiction middle grade novel set at the turn of the century, an 11-year-old girl explores the natural world, learns about science and animals, and grows up. A Newbery Honor Book. “The most delightful historical novel for tweens in many, many years. . . . Callie's struggles to find a place in the world where she'll be encouraged in the gawky joys of intellectual curiosity are fresh, funny, and poignant today.” —The New Yorker Calpurnia Virginia Tate is eleven years old in 1899 when she wonders why the yellow grasshoppers in her Texas backyard are so much bigger than the green ones. With a little help from her notoriously cantankerous grandfather, an avid naturalist, she figures out that the green grasshoppers are easier to see against the yellow grass, so they are eaten before they can get any larger. As Callie explores the natural world around her, she develops a close relationship with her grandfather, navigates the dangers of living with six brothers, and comes up against just what it means to be a girl at the turn of the century. Author Jacqueline Kelly deftly brings Callie and her family to life, capturing a year of growing up with unique sensitivity and a wry wit. The Evolution of Calpurnia Tate by Jacqueline Kelly was a 2010 Newbery Honor Book and the winner of the 2010 Bank Street - Josette Frank Award. This title has Common Core connections. This is perfect for young readers who like historical fiction, STEM topics, animal stories, and feminist middle grade novels. Don't miss the sequel! The Curious World of Calpurnia Tate To follow Calpurnia Tate on more adventures, read the Calpurnia Tate, Girl Vet chapter book series: Skunked! Counting Sheep Who Gives a Hoot? A Prickly Problem
Globalisation, and the vast migrations of capital and labour that have accompanied it in recent decades, has transformed family law in once unimaginable ways. Families have been torn apart and new families have been created. Borders have become more porous, allowing adoptees and mail order brides to join new families and women fleeing domestic violence to escape from old ones. People of different nationalities marry, have children, and divorce, not necessarily in that order. They file suits in their respective home states or third states, demanding support, custody, and property. Otherwise law-abiding parents risk jail in desperate efforts to abduct their own children from foreign ex-spouses. The aim of this Handbook is to provide scholars, postgraduate students, judges, and practioners with a broad but authoritative review of current research in the area of International Family Law. The contributors reflect on a range of jurisdictions and legal traditions and their approaches vary. Each chapter has a distinct subject matter and was written by an author who was invited because of his or her expertise on that subject. This volume provides a valuable contribution to emerging understandings of the subject.
In an era far removed from the African American celebrity athletes of today, Olympic great Jesse Owens achieved fame by running faster and jumping farther than anyone in the world. Author Jacqueline Edmondson explores Owens' struggles and hard-earned accomplishments, as well as how he paved the way for future generations of athletes, including color-line shatterer Jackie Robinson. It is difficult to imagine a time when African Americans were not part of professional sports in the United States. So many admired and beloved African-American athletes are national heroes today: Michael Jordan, Venus and Serena Williams, Tiger Woods, Florence Griffin-Joyner, Shaquille O'Neal, Muhammad Ali, to name a few. No such celebrity athletes appeared on magazine covers when Jesse Owens was a boy in the 1920s, no African American stars for him to hope to emulate. As the first American in track and field to win four gold medals in a single Olympic Games, Owens' athletic accomplishments were achieved despite seemingly insurmountable odds. This insightful biography tells the life story of a boy who grew up in poverty in the Deep South, won Olympic gold in Hitler's Germany by running faster and jumping farther than anyone in the world, and achieved fame and sometimes fortune in the midst of the Great Depression and a nation deeply divided by race. Yet while Owens broke world records in track and gained attention from the general public, few athletes could understand his experiences, including the overt racial discrimination he faced-even fewer who understood the complexities his fame brought. Author Jacqueline Edmondson explores Owens' struggles and hard-earned accomplishments, as well as how he paved the way for future generations of athletes, including color line shatterer, Jackie Robinson. A timeline, photos, and extensive bibliography of print and electronic sources supplement this biography of one of the greatest Olympic athletes in American history.
In this masterful portrait of life in Savannah before, during, and after the Civil War, prize-winning historian Jacqueline Jones transports readers to the balmy, raucous streets of that fabled Southern port city. Here is a subtle and rich social history that weaves together stories of the everyday lives of blacks and whites, rich and poor, men and women from all walks of life confronting the transformations that would alter their city forever. Deeply researched and vividly written, Saving Savannah is an invaluable contribution to our understanding of the Civil War years.
As a medical doctor and daughter of a skin-cancer survivor, Dr. Jacqueline Schaffer has created a unique guide to the complicated world of Skincare. This book provides valuable insight into how the skincare regimen you adhere to, the products you choose, your diet and nutrition, and fitness routine affects your skin. Written to provide help to ALL skin types, How to Get Clear Skin includes recipes, how to guides, skincare product and makeup recommendations based on YOUR specific skin type - giving you a step-by-step manual to look and feel your very best.
This investigation into Karl Lagerfeld’s (1933–2019) artistry explores his extraordinary sixty-five-year career, from the designs for Chloé and Fendi in the 1960s and 1970s to his celebrated leadership in the 1980s and beyond at Chanel and his own label. Inspired by the “line of beauty” theorized by eighteenth-century English painter William Hogarth, this dazzling publication pursues the straight and serpentine “lines” and their intersections in Lagerfeld’s work as a means of understanding his unique creative process.
Accusations of betrayal played a significant role in the shaping and maintenance of solidarity in socialist and other modern radical political organisations in Australia and Britain. This fascinating study of trust and betrayal focuses on case studies of 6 'rats' or renegades: H.H. Champion; William Trenwith; John Burns; Albert Victor Grayson; Adela Pankhurst Walsh; and Ada Holman. Renegades and Rats will appeal to scholars of history and sociology alike, and to anyone intersted in the subject of trust: what it is, and how it is lost.
This textbook provides an interdisciplinary overview of theories of crime, explanations of how and why criminal typologies are developed, literature reviews for each of the major crime catagories, and discussions of how theories of crime are used at different stages of the criminal justice process.
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