The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.
Mah bh rata (including Harivam a) and R m yan a, the two great Sanskrit Epics central to the whole of Indian Culture, form the subject of this new work.The book begins by examining the relationship of the epics to the Vedas and the role of the bards who produced them. The core of the work, a study of the linguistic and stylistic features of the epics, precedes the examination of the material culture, the social, economic and political aspects, and the religious aspects. The final chapter presents the wider picture and in conclusion even looks into the future of epic studies.In this long overdue survey work the author synthesizes the results of previous scholarship in the field. Herewith a coherent view is built up of the nature and the significance of these two central epics, both in themselves, and in relation to Indian culture as a whole.
A selection of themes from the two religions of Hinduism and Christianity, chosen to highlight the central concerns of both, while not neglecting their internal diversity and also maintaining a balance between doctrine and practice, in order to compare like with like. The themes addressed are the nature of the divine, divine interaction with mankind, authority and mediation, devotionalism and personal piety, meditation and asceticism, social values and morality, and teleology; the final chapter then outlines the history of contact and dialogue between the two religions. Although the treatment is thematic, the process of historical development is given due attention.
Delegates to the 3rd International Conference on Environmental and Economic Impact on Sustainable Development contributed the peer-reviewed papers contained in this book. The papers discuss the most serious problems affecting sustainable development. They consider the impact of economic constraints on the environment, taking into account the social aspects as well as the over-use of natural resources. Uncontrolled development can also result in damage to the environment in terms of the release of toxic substances and hazardous waste. Thus, attention is paid to issues related to whether some forms of development are compatible with environmental protection, particularly in cases of possible serious contamination and toxicity. The focus in the book is on more constructive and progressive approaches to the problems discussed, to ensure sustainability. The hope is that through the shared experiences of experts, we can learn from past failure, to avoid repeating similar mistakes, while attempting to prevent emerging threats to the environmental and ecological systems. Fundamental to these concepts are an analysis of the inherent risks and the development of appropriate strategies. The papers in this book cover such topics as: Environmental assessments; Environmental policies and planning; Water resources management; Natural resources management; Legislation and regulations; Development issues; Economic impact.
Six years after the symposium on Stability and Stabilization of Enzymes, a second symposium, Stability and Stabilization of Biocatalysts, on which this book is based, was organized. At the symposium, 210 participants representing all continents came together to learn from 150 oral and poster communications.The volume brings up-to-date the work already going on, and identifies possible breakthroughs in the research. This timely book therefore presents cutting edge developments in topics such as non-covalent processes in solution, protein engineering and thermophile enzymes, immobilized enzymes, non-conventional media, and whole cells.An excellent addition to the available literature, it will make a useful contribution to this key area of applied biocatalysis.
Hydrocarbon Fluid Inclusions in Petroliferous Basins trains readers to detect Hydrocarbon Fluid Inclusions (HCFIs) in sedimentary rocks, particularly the wafer preparation techniques to visualize HCFIs, its distinction from aqueous inclusions, petrographic approaches to HCFIs, microthermometric observations on HCFIs, fluorescence emission spectra and Raman spectra of HCFIs, and their interpretations for the petroleum industry. The book features case studies from the Mumbai and Kerala Konkan Basins of the Western Offshore of India - two representative basins where new, non-destructive, fluid inclusion techniques were tested. This book is essential reading for students of petroleum geology and those working in exploration in the oil and gas industry. - Helps readers to identify Hydrocarbon Fluid Inclusions (HCFIs) in sedimentary basins - Covers how to determine the oil window, API gravity and chemical constituents in HCFIs - Includes case studies on key offshore basins
The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.
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