The confluence of the fields of liquid crystals and biomedical engineering is resulting in remarkable interdisciplinary research. This book focuses on the potential for inherently translational research in one field of engineering to radically alter the scope of another. The text reviews the exciting advances being made in displays, spectroscopy, sensors and diagnostics, biomimicking, actuators and lasers with regards to liquid crystalline materials, and biomedicine. The liquid crystal field ? which has delivered revolutionary devices in the display, optics, and telecommunications industries ? is now poised to make significant inroads into biology, medicine, and biomedical engineering.
Vascular Protection explores advances in vascular biology and how they translate into innovations in drug therapy for vascular disease. It addresses recent advances in the knowledge of endothelial vasoactive factors and other biologically active molecules as well as gene therapy. Written by leading experts in their respective fields, each chapter e
The term rapid prototyping (RP) refers to a generic group of emerging technologies that enable very quick fabrication of engineering components primarily targeted for prototyping applications. With RP, very complex three dimensional parts or prototypes can be fabricated without the need of costly tooling and machining. This inevitably leads to much shorter design cycle time and lower cost of building a prototype. Its manifold benefits include significant productivity gains, cost saving, and shortened development time to introduce concept models. As such, RP technologies have attracted tremendous R&D interests from both academia and industry in the past decade. Many different processes and materials have been commercialized and used in industry primarily for the fabrication of physical prototypes. More recent interests in RP technologies are towards functional applications of the fabricated parts, such as in rapid tooling applications and replacements of damaged components. Many processes and materials have been commercialized but are yet to be able to fulfill the aforementioned functional requirements because of limited mechanical strengths of the fabricated parts.
For more than 35 years, Kaufman’s Clinical Neurology for Psychiatrists has been the only reference to focus on the must-know aspects of neurology for psychiatrists. Now in a revised 8th Edition, this classic text brings you up to date with essential knowledge in clinical neurology with new topics, new illustrations, and new questions to help you excel on the American Board of Psychiatry and Neurology examination. Explains each condition's neurologic and psychiatric features, easily performed office and bedside examinations, appropriate tests, differential diagnosis, and management options. Discusses timely, clinically-relevant topics such as traumatic brain injury, Alzheimer and non-Alzheimer dementias, other age-related neurologic conditions, neurologic illnesses that present with symptoms of autism, neurologic effects of illicit drug use, and current treatments. Correlates neurologic illnesses with the DSM-5. Includes nearly 2,000 multiple-choice questions both in print and online, – all written to help you succeed on the ABPN certifying exam. Features new and improved clinical illustrations throughout: life-like patient sketches, anatomy line drawings, CTs, MRIs, and EEGs that demonstrate clinical features.
This work covers the maximal and prime ideals of the incidence algebra, derivations and isomorphisms, radicals and additional ring-theoretic properties. Combinatorial discussions include a study of the Mobius function, reduced incidence subalgebras, and the coalgebra approach to incidence algebras.
This first-of-its-kind publication reviews the most impor-tant literature on the synthesis, properties, and applications of telechelic polymers. Written by a group of internationally known ex-perts in the field, this text contains a review table which allows the reader to search for given polymers with given end groups. Over 1,250 references are listed, covering primary and review articles as well as patents. Chapters include the preparation of telechelics by stepwise polymerization, anionic polymerization, radical polymer-ization, cationic polymerization, ring-opening polymerization and controlled polymer degradation. Polyols for the polyurethane pro-duction are described, as well as halato-telechelic polymers. Also, a more theoretical contribution on the physical properties of net-works formed from telechelic polymers is provided.
From its origins in the minimization of integral functionals, the notion of variations has evolved greatly in connection with applications in optimization, equilibrium, and control. This book develops a unified framework and provides a detailed exposition of variational geometry and subdifferential calculus in their current forms beyond classical and convex analysis. Also covered are set-convergence, set-valued mappings, epi-convergence, duality, and normal integrands.
Metallic Powders for Additive Manufacturing Overview of successful pathways for producing metal powders for additive manufacturing of high-performance metallic parts and components with tailored properties Metallic Powders for Additive Manufacturing introduces the readers to the science and technology of atomized metal powders beyond empirical knowledge and the fundamental relationships among the chemistry, microstructure, and morphology of atomized metallic powders and their behavior during additive manufacturing. The text sets a foundation of the underlying science that controls the formation and microstructure of atomized metallic droplets, including the relations among the properties of metallic powders, their performance during the manufacturing processes, and the resulting products. Other topics covered include the influence of powder on defect formation, residual stress, mechanical behavior, and physical properties. The concluding two chapters encompass considerations of broader societal implications and overarching themes, including the exploration of alternative feedstock materials, economic analysis, and sustainability assessment. These chapters offer valuable perspectives on the prospective trajectory of the field. Written by a team of experienced and highly qualified professors and academics, Metallic Powders for Additive Manufacturing includes information on: Atomization techniques such as Vacuum Induction Gas Atomization (VIGA), Electrode Induction Melting Gas Atomization (EIMGA), and Plasma Rotating Electrode Process (PREP) Atomization science and technology, covering control of atomization parameters, powder size distribution, effect of processing variables, and theoretical models of atomization Heat transfer and solidification of droplets, covering nucleation, microstructure development, and important thermal and solidification conditions during atomization Atomization of Al, Fe, Ni, Co, Ti, and high entropy alloys, as well as composite powders for additive manufacturing, and guidelines for atomization equipment and powder handling Fundamental processing principles in a variety of metal additive manufacturing processes Powder characteristics and requirements for different additive manufacturing processes Effect of powder chemistry and physical characteristics on additive manufacturing processes, and the microstructure and properties of the built parts Evaluation of alternative feedstock sources for metal additive manufacturing, beyond gas atomized powder Economic and sustainability perspectives on powder production and additive manufacturing Metallic Powders for Additive Manufacturing is an excellent combination of rigorous fundamentals and a practice-oriented and forward-looking resource on the subject for materials scientists and practicing engineers seeking to understand, optimize, and further develop the field of powder production and additive manufacturing.
A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.
This book describes every manner in which collagen is involved in normal anddisease-altered states of the various organs and systems. In the first part of the book the biochemical aspects of collagens are reviewed, including their structure, heterogeneity, syntheses, and degradation. The main part focuses on the involvement of collagen in bone, cartilage, tendon, muscle, heart, vessels, lungs, liver, skin, eye, ear, teeth, periodontal tissues, kidneys and reproductive, hemopoietic,and nervous systems. The influence of radiation and nutrition on collagen, the role of collagen in neoplasms, the hormonal control of its metabolism, immunobiology and the pharmacology of collagen are also described. The most important feature of the book is the comprehensive review of the medical aspects of collagen, from those known in detail to those only hypothesized including hereditary disorders affecting collagen and so-called collagen diseases. Each chapter reviewsknown or possible mechanisms of collagen involvement and changes in indices of collagen which can be measured in clinical practice to monitor these phenomena. The fact that collagen is involved into the pathophysiology of almost all organs and body systems means that physicians in almost all branches of medicine will find this book of great interest.
Aerosols play a critical role in a broad range of scientific disciplines, such as atmospheric chemistry and physics, combustion science, drug delivery and human health. This thesis explores the fundamentals of a new technique for capturing single or multiple particles using light, and for characterising these particles by Raman or fluorescence spectroscopy. The outcome of this research represents a significant development in optical manipulation techniques, specifically in optical tweezing. These findings can be applied to studies of the mass accommodation of gas-phase water molecules adsorbing onto a water surface. Not only is this a fundamental process of interest to physical chemists, but it is important for understanding the role of aerosol particles in the atmosphere, including their ability to become cloud droplets. This new strategy for investigating aerosol dynamics is fundamental in helping us understand the indirect effect of aerosols on the climate.
Expertly bridging the gap between basic science and clinical information, Williams Textbook of Endocrinology, 14th Edition, brings together an outstanding collection of world-renowned authors to provide authoritative discussions of the full spectrum of adult and pediatric endocrine system disorders. New chapters and significant revisions throughout keep you up to date with recent advances in medications, therapies, clinical trials, and more. This essential reference is a must-have resource for endocrinologists, endocrine surgeons, gynecologists, internists, pediatricians, and other clinicians who need current, comprehensive coverage of this multifaceted field. - Up to date with recent advances in medications, therapies, and clinical trials. - Provides state-of-the-art coverage of diabetes, metabolic syndrome, metabolic bones disorders, obesity, thyroid disease, testicular disorders, newly defined adrenal disorders and much more - all designed to help you provide optimal care to every patient. - Contains new chapters on Global Burden of Endocrine Disease, Navigation of Endocrine Guidelines, and Transgender Endocrinology. - Includes significant updates to the Diabetes section, including a new chapter on Physiology of Insulin Secretion and greater coverage of Type 2 Diabetes. - Presents current information in a highly illustrated, user-friendly format for quick reference. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Safely and effectively treat a full range of skin disorders with Comprehensive Dermatologic Drug Therapy, 3rd Edition! This trusted dermatology reference provides concise, complete, up-to-date guidance on today's full spectrum of topical, intralesional, and systemic drugs. Dr. Steven E. Wolverton and a team of leading international experts clearly explain what drugs to use, when to use them, and what to watch out for. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you’re using or where you’re located. Prescribe with confidence thanks to quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Assess your knowledge and prepare for certification or recertification with more than 800 review questions and answers throughout. Contain costs and meet patient expectations with purchase information provided for major drugs. Quickly evaluate drug options for each disease discussed using a highly detailed, disease-specific index. Discover the best uses for new biologic therapeutics such as ustekinumab and rituximab, as well as newly improved TNF inhibitors. Offer your patients the very latest in cosmetic procedures, including chemical peels, intradermal fillers, and botulinum toxin. Use the safest and most effective drugs possible with new chapters on irritants and allergens in topical therapeutic agents, plus a new, separate chapter on mycophenolate mofetil. Review drugs recently taken off the market by the FDA, and use that knowledge to improve your current dermatologic drug therapy.
Internationally lauded as the preeminent text in the field, Campbell-Walsh Urology continues to offer the most comprehensive coverage of every aspect of urology. Perfect for urologists, residents, and practicing physicians alike, this updated text highlights all of the essential concepts necessary for every stage of your career, from anatomy and physiology through the latest diagnostic approaches and medical and surgical treatments. The predominant reference used by The American Board of Urology for its examination questions. Algorithms, photographs, radiographs, and line drawings illustrate essential concepts, nuances of clinical presentations and techniques, and decision making. Key Points boxes and algorithms further expedite review. Features hundreds of well-respected global contributors at the top of their respective fields. A total of 22 new chapters, including Evaluation and Management of Men with Urinary Incontinence; Minimally-Invasive Urinary Diversion; Complications Related to the Use of Mesh and Their Repair; Focal Therapy for Prostate Cancer; Adolescent and Transitional Urology; Principles of Laparoscopic and Robotic Surgery in Children; Pediatric Urogenital Imaging; and Functional Disorders of the Lower Urinary Tract in Children. Previous edition chapters have been substantially revised and feature such highlights as new information on prostate cancer screening, management of non–muscle invasive bladder cancer, and urinary tract infections in children. Includes new guidelines on interstitial cystitis/bladder pain syndrome, uro-trauma, and medical management of kidney stone disease. Anatomy chapters have been expanded and reorganized for ease of access. Boasts an increased focus on robotic surgery, image-guided diagnostics and treatment, and guidelines-based medicine. Features 130 video clips that are easily accessible via Expert Consult. Periodic updates to the eBook version by key opinion leaders will reflect essential changes and controversies in the field. Expert Consult eBook version included with purchase. This enhanced eBook experience offers access to all of the text, figures, tables, diagrams, videos, and references from the book on a variety of devices.
Therapy in Sleep Medicine, by Drs. Teri J. Barkoukis, Jean K. Matheson, Richard Ferber, and Karl Doghrami, provides the clinically focused coverage you need for rapid diagnosis and effective treatment of sleep disorders. A multidisciplinary team of leading authorities presents the latest on sleep breathing disorders (including obstructive sleep apnea), neuropharmacology, parasomnias, neurologic disorders affecting sleep, sleep therapy for women, sleep therapy in geriatric patients, controversies, and future trends in therapy in a highly illustrated, easy-to-follow format. Diagnose and treat patients effectively with complete coverage of the full range of sleep disorders. Find diagnostic and treatment information quickly and easily thanks to a highly illustrated, easy-to-read format that highlights key details. Stay current on discussions of hot topics, including sleep breathing disorders (including obstructive sleep apnea), neuropharmacology, parasomnias, neurologic disorders affecting sleep, sleep therapy for women, sleep therapy in geriatric patients, controversies, and future trends in therapy. Tap into the expertise of a multidisciplinary team of leading authorities for well-rounded, trusted guidance.
Since 1954, Campbell-Walsh Urology has been internationally recognized as the pre-eminent text in its field. Edited by Alan J. Wein, MD, PhD(hon), Louis R. Kavoussi, MD, Alan W. Partin, MD, PhD, Craig A. Peters, MD, FACS, FAAP, and the late Andrew C. Novick, MD, it provides you with everything you need to know at every stage of your career, covering the entire breadth and depth of urology - from anatomy and physiology through the latest diagnostic approaches and medical and surgical treatments. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, definitive text in the field! Required reading for all urology residents, Campbell-Walsh Urology is the predominant reference used by The American Board of Urology for its board examination questions. Visually grasp and better understand critical information with the aid of algorithms, photographs, radiographs, and line drawings to illustrate essential concepts, nuances of clinical presentation and technique, and decision making. Stay on the cutting edge with online updates. Get trusted perspectives and insights from hundreds of well-respected global contributors, all of whom are at the top and the cutting edge of their respective fields. Stay current with the latest knowledge and practices. Brand-new chapters and comprehensive updates throughout include new information on perioperative care in adults and children, premature ejaculation, retroperitoneal tumors, nocturia, and more! Meticulously revised chapters cover the most recent advancements in robotic and laparoscopic bladder surgery, open surgery of the kidney, management of metastic and invasive bladder cancer, and many other hot topics! Reference information quickly thanks to a new, streamlined print format and easily searchable online access to supplemental figures, tables, additional references, and expanded discussions as well as procedural videos and more at www.expertconsult.com.
Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease. The book includes 23 completely new chapters, and has updated information on: Genetics Pathology Biomarkers Pathogenesis Impulse control disorders in Parkinson's disease Updated outcome measures Complementary and alternative medicine for the treatment of Parkinson's disease Together the chapters form a comprehensive review of the many issues facing PD physicians today. Lucid and easily readable from beginning to end, each chapter may also stand on its own as a scholarly review of the individual subject. Each one is concisely written and heavily referenced for this purpose. The second edition of Parkinson's Disease: Diagnosis and Clinical Management provides a state-of-the-art review of where we've been, where we are now, and where we are going in treating this disease.
From new research and equipment to new procedures, applications, and approaches, the field of interventional cardiology is one of the fastest-changing areas in medicine. Increasing data and recent technological advances have resulted in exciting changes – and an even greater need for cutting-edge, authoritative guidance on current practice. Textbook of Interventional Cardiology, 8th Edition, covers the theories, trends, and applications of diagnostic and interventional cardiology that cardiologists, cardiac surgeons, vascular surgeons, referring physicians, and advanced practitioners need to know. - Focuses on the latest treatment protocols for managing patients at every level of complexity. - Includes all-new chapters on Coronary Stenting, Diagnosis and Treatment of Coronary Microvascular Disease, Percutaneous Transcatheter Valve in Valve Implantation, and Percutaneous Tricuspid Valve Repair. - Features hundreds of new illustrations, tables, and boxes for visual clarity and quick reference. - Offers expanded coverage of transcatheter aortic valve interventions with extensive updates on practice implications. - Discusses hot topics such new atherectomy devices, percutaneous mitral valve replacement, and percutaneous treatment of paravalvular leak. - Provides the unique insights of expert leaders in the field who have pioneered today's innovative devices and techniques and lend their own analysis of practical, evidence-based clinical applications. - Presents the most recent data on how genomics and genetics impact interventional cardiology. - Provides an in-depth understanding of cardiology, making it well suited for cardiology and interventional cardiology exam preparation. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
ENDOCRINOLOGY, edited by J. Larry Jameson, MD, PhD and Leslie J. De Groot, MD, has been considered the definitive source in its field for decades. Now this landmark reference has been exhaustively updated to bring you the latest clinical guidance on all aspects of diagnosis and treatment for the full range of endocrine and metabolism disorders, including new information on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors. Entirely new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis keep you well informed on today’s hot topics. You’ll benefit from unique, global perspectives on adult and pediatric endocrinology prepared by an international team of renowned authorities. This reference is optimally designed to help you succeed in your demanding practice and ensure the best possible outcomes for every patient. Overcome virtually any clinical challenge with detailed, expert coverage of every area of endocrinology, authored by hundreds of leading luminaries in the field. Provide state-of-the-art care with comprehensive updates on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors ... brand-new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis ... expanded coverage of sports performance, including testosterone, androgen research, and bone growth and deterioration ... and the newest discoveries in genetics and how they affect patient care. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. Rapidly consult with trusted authorities thanks to new expert-opinion treatment strategies and recommendations. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information more quickly, while still getting the complete coverage you expect.
Introducing Language in Use, second edition, provides a lively and accessible introduction to the study of language and linguistics. Drawing on a vast range of data and examples of language in its many forms, this book provides students with the tools they need to analyse real language in diverse contexts. The second edition of this best-selling textbook has been fully revised and updated with entirely new chapters on Phonology and Sociolinguistics, two separate chapters on syntax and grammar, completely rewritten chapters on Multilingualism, Psycholinguistics and World Englishes, and a greater focus on corpus linguistics. Introducing Language in Use: covers all the core areas and topics of language study, including semiotics, communication, grammar, phonetics, phonology, words, semantics, variety in language, history of English, world Englishes, multilingualism, psycholinguistics, sociolinguistics, language acquisition, conversation analysis, pragmatics and politeness adopts a 'how to' approach, encouraging students to apply their knowledge as they learn it draws on examples of language from around the world in forms ranging from conversation to advertising and text messaging, always giving precedence to real language in use includes activities throughout the text and an extensive glossary of terms The book is supported by a companion website offering a wealth of additional resources including commentaries on the activities in the book, suggested further reading and references, links to useful websites, more texts to analyse, additional web activities, ‘fun with language’ exercises, discussion questions and an additional ‘Language in Education’ chapter. This is an essential coursebook for all introductory courses in English language, communication and linguistics. Visit the companion website at www.routledge.com/cw/merrison
Ideal for cardiologists, surgeons, and referring physicians who need a clinical guide to interventional procedures, Textbook of Interventional Cardiology focuses on the latest treatment protocols for managing heart disorders at every level of complexity. In this updated edition, Dr. Topol continues to bring together experts in the field who present the current state of knowledge and clinical practice in interventional cardiology, including cutting-edge theories, trends, and applications of diagnostic and interventional cardiology, as well as peripheral vascular techniques and practices. Offers an in-depth understanding of cardiology, making it well suited for cardiology and interventional cardiology exam preparation. Expert guidance from leading authorities ensures a fresh and balanced perspective on every aspect of interventional cardiology. Presents the most recent genetic information and clinical trials related to interventional cardiology. Highlights the latest treatment advances, procedures, devices, and techniques, including transcatheter aortic valve implantation (TAVI). Brand-new chapters include Radiation Safety, Renal Denervation for Resistant Hypertension, Post PCI Hospitalization, Length of Stay and Discharge Planning, and Interventional Heart Failure. Offers balanced coverage of the entire scope of technologies available, without favoring one particular device over another. Integrates the latest trial data into discussions on clinical practice and recommendations. Multiple images of devices and intra-procedural imaging enhance your visual understanding of the material. Key Points boxes at the beginning of each chapter summarize the most important facts. Features 45 videos easily accessible via Expert Consult. Expert Consult eBook version included with purchase. This enhanced eBook experience offers access to all of the text, figures, videos, and references from the book on a variety of devices.
Conversation is one of the most widespread uses of human language, but what is actually happening when we interact this way? How is conversation structured? How does it function? Answering these questions and more, An Introduction to Conversation Analysis is an essential overview of this topic for students in a wide range of disciplines including sociolinguistics, discourse analysis and sociology. This is the only book you need to learn how to do conversation analysis. Beginning by positioning conversation analysis amongst other methodologies, this book explains the advantages before guiding you step-by-step through how to do conversation analysis and what it reveals about the ways language works in communication. Chapters introduce every aspect of conversation analysis logically and clearly, covering topics such as transcription, turn-taking, sequence organisation, repair, and storytelling. Now fully revised and expanded to take account of recent developments, this third edition includes: - 3 new chapters, covering action formation and epistemics, multimodality and spoken interaction, and written conversation - New topics including online and mobile technology, cross-cultural conversation and medical discourse - A glossary of key terms, brand new exercises and updated lists of further reading - A fully updated companion website, featuring tutorials, audio and video files, and a range of different exercises covering turn taking, organisation and repair
Over 30,000 entries to current medical terminology. Intended to serve personnel in the health sciences. Also includes taxonomic terminology, eponyms, and abbreviations. Tables of arteries, bones, muscles, nerves, synovial joints, ligaments, and veins.
The Australide orogen, the southern hemisphere Neoproterozoic to Mesozoic terrane accretionary orogen that forms the palaeo-Pacific margin of Gondwana, is one of the largest and longest-lived orogens on Earth. This book brings together a series of reviews and multidisciplinary research papers that comprehensively cover the Australides from the Tasman orogen of eastern Australia to the Neoproterozoic and Palaeozoic orogens of South America, taking in New Zealand and Antarctica along the way. It deals with the evolution of the southern Gondwana margin, as it grew during a series of terrane accretion episodes from the late Proterozoic through to final fragmentation in mid-Cretaceous times. Global perspectives are given by comparison with the Palaeozoic northern Gondwana margin and documentation of world-wide terrane accretion episodes in the Late Triassic-Early Jurassic and mid-Cretaceous. The Tasmanides of eastern Australia, and the terrane histories of New Zealand and southern South America are given comprehensive up-to-date reviews.
Completely updated edition, written by a close-knit author team Presents a unique approach to stroke - integrated clinical management that weaves together causation, presentation, diagnosis, management and rehabilitation Includes increased coverage of the statins due to clearer evidence of their effectiveness in preventing stroke Features important new evidence on the preventive effect of lowering blood pressure Contains a completely revised section on imaging Covers new advances in interventional radiology
Many genes have been cloned from chicken cells, and during the next decade numerous laboratories will be concentrating their resources in developing ways of using these tools. Manipulation of the Avian Genome contains the most recent information from leading research laboratories in the areas of developmental and molecular genetics of the chicken. This information was presented at the Keystone Symposium held at Lake Tahoe in March, 1991. The book discusses potential applications of emerging technology in basic science and poultry production. Various techniques for altering genomic DNA, such as microinjection, retroviral vectors, and lipofection are covered. Genome evaluation using DNA fingerprinting and conventional breeding techniques are presented.
Advanced Metrology: Freeform Surfaces provides the perfect guide for engineering designers and manufacturers interested in exploring the benefits of this technology. The inclusion of industrial case studies and examples will help readers to implement these techniques which are being developed across different industries as they offer improvements to the functional performance of products and reduce weight and cost. - Includes case studies in every chapter to help readers implement the techniques discussed - Provides unique advice from industry on hot subjects, including surface description and data processing - Features links to online content, including video, code and software
An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.
This state-of-the-art reference details current and effective symptom-specific strategies for the diagnosis and management of diabetic patients-emphasizing the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes. Addresses the pathophysiology underlying advanced heart
Efficiently review the latest clinical recommendations, developments, and procedures with Women’s Health Review. This comprehensive, yet succinct summary is just the medical reference book you need to ensure that your knowledge is up to date! Zero in on the most important new information with "update boxes," and dig deeper into the surrounding text for more background or complementary discussions. Review key points quickly with the aid of relevant tables and images. Take an organized approach to review with a subspecialty-based structure and a convenient outline format. Get the authoritative coverage you need thanks to the collaboration of contributions from University of California medical schools, each at the top of their specialty.
Principles of Cardiac and Vascular Computed Tomography has everything you need to successfully obtain and interpret CT and CTA images. Stuart J. Hutchison-a premier cardiac imaging specialist-explains the dos and don’ts of CCT so you get the best images and avoid artifacts. Get only the coverage-from evidence-based CTA to noncoronary lesions-you need with clinically oriented, practical information presented in a consistent format that makes finding everything quick and easy. High-quality images and access to the text and more at Expert Consult makes this the one cardiovascular computed tomography resource that has it all. Access videos of CTA procedures at Expert Consult. Get only the coverage that you need-from evidence-based CTA to determination of coronary calcium to noncoronary lesions-from focused, clinically oriented, and practical information. Obtain the best image quality and avoid artifacts through instructions on how to and how not to perform cardiovascular computed tomography. Gain a clear visual understanding through high-quality images-many in color-that reinforce the quality of information in the text. Master probe settings and measurements using numerous tables with useful values and settings. Find information easily thanks to a consistent format.
Reprint of the original, first published in 1874. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Often, the tissues involved require certain mechanical and structural properties for proper function. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bioartificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues. This book presents recent and important research in the field.
This authoritative introduction to African American English (AAE) is the first textbook to look at the grammar as a whole. Clearly organised, it describes patterns in the sentence structure, sound system, word formation and word use in AAE. The textbook examines topics such as education, speech events in the secular and religious world, and the use of language in literature and the media to create black images. It includes exercises to accompany each chapter and will be essential reading for students in linguistics, education, anthropology, African American studies and literature.
Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.
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