The history of science has shown the majority of hypotheses to be wrong. Sharp scientific criticism and strictly controlled experimental studies reject most of the hypotheses, leaving behind only a small number of assumptions and ideas. Nevertheless, each logical assumption should have its rightful place on the scientific “battlefield” supposed to assess its validity and determine its final fate. Even when a hypothesis is wrong, it still finds its place in the entire efforts of the humankind towards attaining the scientific truth. Namely, the wrong hypotheses serve largely to illuminate the way towards the correct ones or, at least, to show which way not to follow. Correct or not, ideas and hypotheses are necessary for the progress of science. They epitomize the efforts of human thought to elucidate nature without experimental verification and in the circumstances of scant data availability. Finally, hypotheses and ideas represent a symbiotic creation of our knowledge and imagination, the two most impressive appearances in the evolution of humans.
The new fifth edition of Managerial Economics is an ideal text for any course focusing on the practical application of micro-economic principles to management. It includes fresh up-to-date discussion questions from all over the world and is enhanced with detailed instructor supplements. The book is a popular, useful choice for managers learning economics. An accompanying website, featuring a wealth of supplementary material, is available at https://sites.google.com/site/pngecon/
This book has been designed to summarize current, essential information for every one of the world’s 700+ hard tick species. Under each species name, we will cite the original description, followed by information on type depositories, known stages, distribution (by zoogeographic region and ecoregion), hosts, and human infestation (if any). Each species account will also include a list of salient references and, where necessary, remarks on systematic status. We envision eight chapters: six devoted to the major ixodid tick genera (Amblyomma, Dermacentor, Haemaphysalis, Hyalomma, Ixodes, Rhipicephalus), one covering eight minor genera (including two that are fossil), and a concluding summary chapter. There will be two tables on host associations and zoogeography in each major genus chapter, as well as five tables in the summary chapter, for a total of 17 tables. No similar synopsis of the world’s hard tick species exists in any language.
Riverhead Books is proud to present our Fall 2013 Insider, which gives readers a peek inside the inspiration, or more information about, the titles on our Fall 2013 list. Included in the Riverhead Books Fall 2013 Insider are: "Black and White and Red All Over" - an essay by Ivan Doig, author of Sweet Thunder "Self-Recognition" - an essay by Najla Said, author of Looking for Palestine "A Changing Landscape" - an essay by Patrick Flanery, author of Fallen Land "My Faulty Faith" - an essay by David Schickler, author of The Dark Path "Behind the Scenes of America's Best High School Theater Program" - a note from Michael Sokolove, author of Drama High "How to Get a Friend to Face a Fear" - a manual by Patty Chang Anker, author of Some Nerve "Captivity Narratives" - an essay by Daniel Alarcón, author of At Night We Walk in Circles "A Detail Map of Palau" - a note from Wil S. Hylton, author of Vanished "The Appeal of the Forbidden" - an essay by Dana Goodyear, author of Anything That Moves "What is an N-Gram?" - a chart by Erez Aiden and Jean-Baptiste Michel, authors of Uncharted
This book is a work of fiction, but it predicts a "Happening" or "Event" that I can guarantee will occur. And the way I know is that it has already occurred several times. Never has the Earth, or the people on it, been so ill-prepared to deal with it. And never has it been so long-overdue as it is now.What if, in a year, a few years, or your lifetime, but within a 24 hour duration, an Event occurred that destroyed nothing, and killed no people, at least directly, but changed the Earth so drastically and overwhelmingly, your mind would marvel at its occurrence, but dread its ramifications?What if the Event took us literally back in time, leveled the playing field for all religions and societies, made all men and women equal, and made money, power, and military force if not non-existent, than practically useless as a means of manipulation?Who would be best equipped to carry on in this New Age, this Brave New World? Would you?
Many philosophers have been appointed to top-level political positions during Chiles modern history. What makes Chilean philosophers unique in the context of Latin America and beyond, is that they have developed a sophisticated rationale for both their participation and withdrawal from politics. All along, philosophers have grappled with fundamental problems such as the role of religion and politics in society. They have also played a fundamental role in defining the nature and aims of higher education. The philosophers production constitutes a substantial, albeit largely unknown, portion of the intellectual history of Chile and Latin America.
Dreams of Love pursues a wide-ranging interdisciplinary approach to understanding the concert pianist as a "Romantic" and seductive-even erotic-figure in the popular imagination, focusing on the role of technology in perpetuating this mythology over the past two centuries through the touch, sights, and sounds of the pianist's playing.
Ivan Ross takes advantage of the significant growth in the amount of new data available to update and expand his much acclaimed Medicinal Plants of the World: Chemical Constituents, Traditional and Modern Medicinal Uses, Volume 1. This considerably enhanced second edition contains new research and references on the immunomodulatory activity present in Allium sativum, Mangifera indica, and Punica granatum, the antidiabetic effects of Momoridica charantia and Mucuna pruriens, the antiinflammatory activity found in Mangifera indica and Arbus precatorius, the cholesterol lowering effect of Allium sativum and Moringa pterygosperma, and the antitumor effect of Arbus precatorius and Moringa pterygosperma. There are also important new findings concerning the antiherpes simplex virus activity of Mangifera indica, the anti-Parkinson's activity of Mucuna pruriens, the antiviral activity in Phyllanthus niruri and Jatropha curcas, the hyperthyroid regulation properties of Moringa pterygosperma, and the antioxidant activity of Mangifera indica, Punica granatum, Psidium guajava, and Allium sativum. Allium sativum is highlighted for its treatment of unstable angina pectoris, sickle red blood cell dehydration inhibition, senescence ameliorative, chemoprotective, cardiovascular, antineoplastic, anticarcinogenic, and antiatherogenic effects. This revised and enhanced edition provides details on traditional medicinal uses, chemical constituents, pharmacological activities, clinical trials, color illustrations, Latin names, botanical descriptions, as well as providing an index and extensive bibliographies. Authoritative and exhaustively compiled, Medicinal Plants of the World: Chemical Constituents, Traditional and Modern Medicinal Uses, Volume 1, 2nd Edition offers pharmacists, physicians, medicinal chemists, toxicologists, and phytochemists a universal reference on twenty-six of the most widely used medicinal plants in the world.
The oceans represent a vast, complex and poorly understood ecosystem. Marine Ecological Processes is a modern review and synthesis of marine ecology that provides the reader with a lucid introduction to the intellectual concepts, approaches, and methods of this evolving discipline. Comprehensive in its coverage, this book focuses on the processes controlling marine ecosystems, communities, and populations and demonstrates how general ecological principles--derived from terrestrial and freshwater systems as well--apply to marine ecosystems. Global warming and increased eutrophication and wetland destruction in recent years has made the study of ecological processes even more important for the preservation of marine environments. This thoroughly updated and expanded edition will provide students of marine ecology, marine biology, and oceanography with numerous illustrations, examples, and references which clearly impart to the reader the current state of research in this field: its achievements as well as unresolved controversies.
Now in one convenient volume, Atlas of Amputations and Limb Deficiencies: Surgical, Prosthetic, and Rehabilitation Principles, Fifth Edition, remains the definitive reference on the surgical and prosthetic management of acquired and congenital limb loss. Developed in partnership with the American Academy of Orthopaedic Surgeons (AAOS) and edited by Joseph Ivan Krajbich, MD, FRCS(C), Michael S. Pinzur, MD, FAAOS, COL Benjamin K. Potter, MD, FAAOS, FACS, and Phillip M. Stevens, MEd, CPO, FAAOP, it discusses the most recent advances and future developments in prosthetic technology with in-depth treatment and management recommendations for adult and pediatric conditions. With coverage of every aspect of this complex field from recognized experts in amputation surgery, rehabilitation, and prosthetics, it is an invaluable resource for surgeons, physicians, prosthetists, physiatrists, therapists, and all others with an interest in this field.
This completely new textbook takes an integrative, problem-based approach to pathophysiology, creating an effective bridge from basic science to clinical practice. Preeminent pathology practitioner, author, and instructor Ivan Damjanov, MD, PhD skillfully provides you with the rich understanding of disease mechanisms you need to succeed on the USMLE and beyond. Clinical vignettes in each chapter, presented in a problem-based format, demonstrate the practical relevance of pathophysiology principles, and hundreds of full-color diagrams clarify even the most difficult concepts. The result is a comprehensive yet succinct source that is ideal for today's medical students. Discussions of each organ system's disorders include key clinical function tests and lab tests - valuable aspects of laboratory medicine that are highly relevant to clinical practice, but are not covered in other pathophysiology texts. A consistent, logical format for each chapter makes the material easy to master. Abundant full-color conceptual diagrams, algorithms, and charts present complex information in an easy-to-absorb manner. Glossaries of key terms, review questions, and other learning tools facilitate study. Clinical case studies help you succeed in problem-based learning courses and on the USMLE.
The leading and definitive reference on the surgical and prosthetic management of acquired and congenital limb loss. The fourth edition of the Atlas of Amputations and Limb Deficiencies is written by recognized experts in the fields of amputation surgery, rehabilitation, and prosthetics.
The present Catalogue comprises information on 48 genera and 1802 valid species of the coleopterous subfamily Scaphidiinae. Unlike previous catalogues of the group, it gives exact type localities, depositories and sexes of primary types whenever traceable. Genera are listed with their type species and grammatical gender. References are given to subsequent taxonomic and nomenclatural acts, records, and to all other relevant information. Distributional information is provided per country, for larger or insular countries per subunits. An overview of fungus and slime mould hosts is annexed. The references to all taxa have been checked by the author. Infrasubspecific entities and priorities are dealt to comply with the ICZN. Nomenclatural problems are highlighted, and several new records are given. Extinct taxa are listed separately.
Because of their simple preparation and low expense, carbon pastes and carbon paste electrodes are widely used in a myriad of instrumental measurements. With an emphasis on practical applications, Electroanalysis with Carbon Paste Electrodes provides a comprehensive overview of carbon paste electrodes. The text offers a comprehensive and unprecedentedly wide insight into the realm of the carbon paste material, culminating with a systematic presentation of all the methods and procedures applicable to the determination of a myriad of inorganic and organic substances when employing the individual types and variants of carbon paste-based electrodes, sensors, and detectors. With a lengthy list of up-to-date references, this handy reference source includes many typical as well as specific experimental data, serving as a practical guide for daily laboratory work. More specifically, this monograph, the first of its kind, contains: All types of carbon pastes in contemporary classification ,with particular emphasis on chemically and biologically modified configurations, or newly propagated mixtures made of alternate components Details on the preparation of carbon pastes, with a number of practical hints and recommendations, including some hitherto unreported approaches Practical guidance for experimental laboratory work on the preparation and characterization of carbon pastes, including guides on the testing of newly made mixtures Individual methods and procedures for the determination of hundreds of various substances in a complete survey of applications Nearly 3300 original references presented as full-text citations
Ophthalmic Surgery, edited by Drs. George Spaeth, Helen Danesh-Meyer, Ivan Goldberg, and Anselm Kampik, provides the detailed, full-color, step-by-step guidance you need to master essential ophthalmic surgery procedures. The international team of expert editors and contributors present coverage of the latest surgical developments and video demonstrations of key techniques across subspecialties, including cataract, cornea, refractive, glaucoma, oculoplastic, extra-ocular muscle, vitreoretinal, and ocular tumor procedures. What’s more, the fully searchable text, procedural videos, and a downloadable image gallery are all online at www.expertconsult.com, making this multimedia resource the key to performing confidently in the operating room. Refer to the most important steps in each procedure quickly and easily with an appendix of step-by-step hand notes. Perform a wide variety of procedures with confidence using the focused coverage that pinpoints essential information and avoids extraneous details. Get comprehensive coverage across key subspecialties—oculoplastic, strabismus, cornea, refractive, cataract, glaucoma, ocular tumors, and vitreoretinal—and master the basics for every common procedure. Access the fully searchable contents online at www.expertconsult.com, along with procedural videos and a downloadable image gallery. Apply the latest advances in laser surgery that have become standard practice with the new section on refractive surgery. Master key techniques thanks to more than four hours of narrated online videos that demonstrate procedures across eight subspecialties. Gain a more nuanced visual understanding through a new full-color art program with over 800 illustrations, updated and revised drawings, color images, and step-by-step illustrated procedures. Tap into the expertise of leading authorities in the field with a brand new editorial team from North America, Europe, and Australasia, as well as international contributors who provide global perspectives across all subspecialties in ophthalmic surgery.
This is the first book-length biography of Andrés Bello, the nineteenth-century Latin American intellectual, to appear in English. Bello was also a poet, a literary critic, and an influential statesman whose contributions to nation-building and Spanish American identity are widely recognized across the region. This work provides a comprehensive interpretation of Bello's work, gives an account of Bello's life based on new information from archives in four countries, and sheds new light on this critical period in Latin American history.
By examining historical applications of the compounds found in plants, this five-volume series serves as a reference for quality assurance, research, product development, and regulatory guidance of the compounds found in plant-based medicines. This work supports the growing consumers' interest in herbal medicine for wellness and health. Plant-Based Therapeutics, Volume 1: Cannabis sativa, the first in the series, covers a unique plant species and provides the framework to integrate its evidence-based scientific discoveries with healthcare therapies. Cannabis has been used in religious ceremonies and medical purposes for thousands of years. Cannabidiol (CBD), the main non-psychoactive component of Cannabis, was isolated in the 1940s, and its structure was established in the 1960s. In 1964 tetrahydrocannabinol (THC), the psychoactive component, was isolated. Cannabis has more than 500 components, of which 104 cannabinoids have been identified. Two of them, THC and CBD, have been the primary components of scientific investigations. They were approved by the FDA for chemotherapy-induced nausea and vomiting in 1985; for appetite stimulation in wasting conditions, such as AIDS, in 1992, and in 2018 for treating two forms of pediatric epilepsy, Dravet syndrome and Lennox-Gastaut syndrome. Beyond the indications for which cannabinoids are FDA-approved, the evidence reveals that cannabinoid receptors are present throughout the body, embedded in cell membranes, and are believed to be more numerous than any other receptor system. When cannabinoid receptors are stimulated, a variety of physiologic processes ensue. Thus, other constituents of Cannabis are extremely promising either as individual compounds or their potential synergistic or entourage effects in the treatment of numerous medical conditions.
An extraordinary compendium of information on herbal medicine, Medicinal Plants of the World, Volume 3 comprehensively documents the medicinal value of 16 major plant species widely used around the world in medical formulations. The book's exhaustive summary of available scientific data for the plants provides detailed information on how each plant is used in different countries, describing both traditional therapeutic applications and what is known from its use in clinical trials. A comprehensive bibliography of over 3000 references cites the literature available from a wide range of disciplines. This book offers an unprecedented collection of vital scientific information for pharmacologists, herbal medicine practitioners, drug developers, medicinal chemists, phytochemists, toxicologists, and researchers who want to explore the use of plant materials for medicinal and related purposes.
The Anesthesiology Review features an unparalleled collection of 1,800 questions, meticulously crafted from 320 specific topics that span the entire spectrum of anesthesiology practice. Each question challenges and expands the reader's understanding, ensuring a solid grasp of both fundamental concepts and advanced techniques. The questions cover the entire field of Anesthesiology, providing a 360-degree view of the field. Access the latest published information, ensuring that readers are not only preparing with comprehensive content but are also up to date with the most current standards and practices in anesthesiology. Each question has been written and reviewed by NYSORA’s team of top experts, guaranteeing a level of precision and expertise that is unmatched. A rationale for the best answer with every question enhances the learning experience, allowing readers to understand not just the 'what,' but the 'why' behind each answer, fostering deeper learning and retention. "Anesthesiology Review" is not just another question book; it is the most comprehensive text available for the review of anesthesia, tailored for both oral and written board examinations. Its format is designed to cater to a wide range of learning preferences.
Scientific and anthropological evidence for multiple Atlantean empires and the global catastrophes that destroyed them • Reveals that there was not one but three Atlantises--the first in Antarctica, the second in South America, and the third in the Mediterranean • Examines geological evidence of super-floods 15,000, 11,600, and 8,700 years ago • Shows how these flood dates directly parallel the freezing of Antarctica, the migrations of Cro-Magnon men, and the destruction of Atlantis according to Plato 15,000 years ago the Earth’s axis tilted, shifting the geographic poles. Volcanoes erupted, the icecaps melted, and the seas rose dramatically. Antarctica was enveloped in ice, destroying the high civilization of prehistory: Atlantis. But before the survivors could reestablish what they had lost, catastrophe struck again--twice. Uniting scientific findings with theories on the location of Atlantis, the authors reveal that there was not one but three Atlantises--the first in Antarctica, the second in South America, and the third in the Mediterranean. Examining paleoclimatology data, they show that Antarctica was temperate 15,000 years ago and home to the original Atlantis. They explore geological evidence of three worldwide super-floods 15,000, 11,600, and 8,700 years ago and show how these dates directly parallel the freezing of Antarctica, the arrival of Cro-Magnon man in Europe, and the destruction of Atlantis according to Plato. Uncovering the influence of the Atlanteans in Proto-Indo-European languages and in massive ancient monuments aligned with the stars, they show how the civilization founders in all early myths--the Pelasgians, Danaans, Viracocha, Aryans, and others--were part of the Atlantean diaspora and how this migration split into two major movements, one to Latin America and the other to Europe and Asia. Following the Atlanteans from a warm Antarctica up to Peru, Mexico, and the Mediterranean, they reveal that Cro-Magnon men are the people of Atlantis and that we are just now returning to their advanced levels of science, technology, and spirituality.
This book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.
This unique book is written with the novice in mind, providing an introduction to all aspects of working with cockroaches. The focus of this writing is on the neuroendocrine system of cockroaches, which was collected by entomologists, primarily with the aim of improving methods of insect pest control. It includes some chapters devoted exclusively to techniques with detailed instructions. This comprehensive work also covers details of anatomy along with illustrations and experimental results. This is one of the few books available which provides such a broad coverage of areas of neurobiology of one organism. This handbook is a must for all researchers in the biomedical/veterinary field. Entomologists will find this reading exciting as well.
Hunger, disease, poverty, environmental insecurity, illegitimate governance, civil war, and international conflict are only a few of the causes of today's global turmoil and gross human suffering. Written in honour of Ivan Head, foreign affairs advisor to former Prime Minister Pierre Trudeau, past president of Canada's International Development Research Centre, and professor emeritus of International law at the University of British Columbia, this collection of distinguished essays addresses the imperative to enhance human dignity and protect human life by humanizing our global order and improving international relations - goals Professor Head strove for throughout his career. The authors argue that the search for possible solutions to these challenges, which has so far tended to proceed without due recognition of the needs, demands, and solutions that emanate from the geo-political South, must in future be conducted with alternate visions that take these factors into account. Each essay seeks to re-assess and re-imagine a specific topic that relates in some significant way to our current global circumstance in ways that advance the book's thematic. With essays grappling with such issues as Multilateral Environmental Agreements, the Use of Force, the Prevention of Civil War through Minority Protection, Common Heritage of Humankind, and the Civil Dimensions of Strategy, the volume deals with a range of diverse topics that are as crucial as they are topical.
Molecular Breeding and Nutritional Aspects of Buckwheat describes the general characterization and genetic diversity of buckwheat (family Polygonaceae, genus Fagopyrum) around the globe (especially in Russia, China, India, and Eastern Europe), the arid and cool regions where it is most frequently consumed, and nutritional information on a variety of buckwheat uses, including tea, groats, flour, and noodles. With detailed information on buckwheat regeneration, genetic transformation, gene function analysis, and the metabolic engineering of bioactive compounds, the book guides readers through a variety of buckwheat varietal adaptations, providing foundation information on which additional research should be conducted. It is divided into four parts, including genetic resource and phylogenetic relationship, food nutrition, growth and cultivation, and molecular breeding, with each section providing insights into the most current developments. - Addresses all aspects of buckwheat research, including genetic resources, biological nutrition, genetic transformation, and molecular breeding - Presents global characterization on the genetic resource of Fagopyrum, giving researchers insights that will help them breed new cultivars - Explores the bioactivity of buckwheat - Includes detailed information on the environmental factors that affect the growth and production of buckwheat
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