Institute of Laboratory Animal Resources's Books

Guide for the Care and Use of Laboratory Animals

Eighth Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals

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Guide for the Care and Use of Laboratory Animals

Eighth Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

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246

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National Academies Press

Published Date

ISBN 10

0309154006

ISBN 13

9780309154000

Guide for the Care and Use of Laboratory Animals

By: Institute of Laboratory Animal Research,Commission on Life Sciences,National Research Council

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Guide for the Care and Use of Laboratory Animals

By: Institute of Laboratory Animal Research,Commission on Life Sciences,National Research Council

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been revised by a committee of experts, based on input from scientists and the public. The Guide incorporates recent research on commonly used species, including farm animals, and includes extensive references. It is organized around major components of animal use: Institutional policies and responsibilities. The committee discusses areas that require policy attention: the role and function of the Institutional Animal Care and Use Committee, protocols for animal care and use, occupational health and safety, personnel qualifications, and other areas. Animal environment, husbandry, and management. The committee offers guidelines on how to design and run a management program, addressing environment, nutrition, sanitation, behavioral and social issues, genetics, nomenclature, and more. Veterinary care. The committee discusses animal procurement and transportation, disease and preventive medicine, and surgery. The Guide addresses pain recognition and relief and issues surrounding euthanasia. Physical plant. The committee identifies design and construction issues, providing guidelines for animal-room doors, drainage, noise control, surgery, and other areas. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities--a resource of proven value, now updated and expanded. This revision will be important to researchers, animal care technicians, facilities managers, administrators at research institutions, policymakers involved in research issues, and animal welfare advocates.

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Page Count

181

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National Academies Press

Published Date

ISBN 10

0309132622

ISBN 13

9780309132626

Guide for the Care and Use of Laboratory Animals -- Korean Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Commission on Life Sciences

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Guide for the Care and Use of Laboratory Animals -- Korean Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Commission on Life Sciences

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128

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National Academies Press

Published Date

ISBN 10

0309103657

ISBN 13

9780309103657

Laboratory Animal Management

Dogs

By: National Research Council,Institute of Laboratory Animal Resources,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on Dogs

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Laboratory Animal Management

Dogs

By: National Research Council,Institute of Laboratory Animal Resources,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on Dogs

This newly revised edition incorporates the regulatory requirements and improved practices for laboratory animal care that have developed over the past two decades. The volume covers: Selection of dogs as research models. Design, construction, and maintenance of facilities. Temperature, humidity, food, water, bedding, sanitation, animal identification, record keeping, and transportation. General veterinary care, as well as special care of breeding animals and random-source animals. Laboratory Animal Management: Dogs examines controversies over proper cage sizes and interpretation of federal requirements for exercise and offers recommendations for researchers. Guidelines are provided on how to recognize and alleviate pain and distress in research dogs and on the sensitive topic of euthanasia. Laboratory Animal Management: Dogs discusses how to assemble a proper research protocol and how to handle conflicts. Outlined are procedures for institutional animal care and use and committee review. The volume also presents guidelines for handling aging dogs, use of radiation in experiments, and a wide range of other special circumstances. Thoroughly referenced, this guide will be indispensable to researchers, research administrators, review committees, and others concerned about laboratory dogs.

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154

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National Academies Press

Published Date

ISBN 10

0309047447

ISBN 13

9780309047449

Rodents

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Rodents

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Rodents

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Rodents

In the 15 years since the last Institute of Laboratory Animal Resources report on the general management of rodents was published, important advances in biomedical research and increased public awareness have created a new environment for animal research. Modern technology-such as insertion of functional genes from other species into mice or rats, elimination of a single selected gene or function in mice, and the re-creation of elements of the human immune system in mice-has greatly expanded the usefulness of rodents in drug development and as models of human diseases. The technologic requirements of such advanced systems have led to improved understanding and implementation of environmental requirements for the care and use of rodents in research. The intent of this report is to provide current information to laboratory animal scientists (including both animal-care technicians and veterinarians), investigators, research technicians, and administrators on general elements of rodent care and use that should be considered both for optimal design and conduct of research and to meet current standards of care and use.

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Page Count

180

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National Academies Press

Published Date

ISBN 10

0309049369

ISBN 13

9780309049368

Guide for the Care and Use of Laboratory Animals -- Japanese Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Commission on Life Sciences

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Guide for the Care and Use of Laboratory Animals -- Japanese Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Commission on Life Sciences

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Page Count

142

Publisher

National Academies Press

Published Date

ISBN 10

0309100186

ISBN 13

9780309100182

Transportation of Laboratory Animals

Proceedings of a Workshop

By: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

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Transportation of Laboratory Animals

Proceedings of a Workshop

By: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

The obligation to treat animals used in research ethically and humanely extends beyond their lives in the laboratory to include their transportation from place to place. Yet transporting animals is a highly regulated and complex process that raises many difficult issues. To examine these issues, the Roundtable on Science and Welfare in Laboratory Animal Use held a workshop on September 3-4, 2014, in Washington, DC. More than 200 people participated in the workshop in person and online, including representatives of academic research institutions, pharmaceutical and consumer product companies, government agencies, research advocacy groups, professional associations, and the public. The workshop was designed to draw attention to the essential thoughtful journey planning behind each transport of laboratory animals.

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Page Count

107

Publisher

National Academies Press

Published Date

ISBN 10

0309373360

ISBN 13

9780309373364

Education and Training in the Care and Use of Laboratory Animals

A Guide for Developing Institutional Programs

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on Educational Programs in Laboratory Animal Science

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Education and Training in the Care and Use of Laboratory Animals

A Guide for Developing Institutional Programs

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on Educational Programs in Laboratory Animal Science

Federal law now requires that institutions provide training for anyone caring for or using laboratory animals. This volume provides the guidelines and resources needed to coordinate a quality training program, as well as to meet all legal requirements. A core module for all personnel takes no more than four hours to present. Most staff then proceed to one or more additional skills-development modules including the species-specific module that can be customized to any species in use at the institution, the pain management module, and the surgery module. The volume provides content information for required topics-from ethics to record keeping-and lists sources of additional publications, audiovisual programs, and computerized teaching aids. Included are: Ready-to-use teaching outlines, with detailed instructions for presenting material. Practical guidelines on logistics, covering scheduling, budgeting, and more. Guidelines on how to design training for adults and how to work with investigators who may resist taking training courses. This practical guidebook will be necessary for research institutions, particularly for staff members responsible for training coordination.

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Page Count

152

Publisher

National Academies Press

Published Date

ISBN 10

0309043824

ISBN 13

9780309043823

The Development of Science-based Guidelines for Laboratory Animal Care

Proceedings of the November 2003 International Workshop

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,International Workshop on the Development of Science-based Guidelines for Laboratory Animal Care Program Committee

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The Development of Science-based Guidelines for Laboratory Animal Care

Proceedings of the November 2003 International Workshop

The Development of Science-based Guidelines for Laboratory Animal Care is the summary of an international workshop held in Washington, DC, in November 2003 to bring together experts from around the world to discuss the available knowledge that can positively influence current and pending guidelines for laboratory animal care, identify gaps in that knowledge in order to encourage future research endeavors, and discuss the scientific evidence that can be used to assess the benefits and costs of various regulatory approaches affecting facilities, research, and animal welfare.

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262

Publisher

National Academies Press

Published Date

ISBN 10

0309093023

ISBN 13

9780309093026

Design, Implementation, Monitoring, and Sharing of Performance Standards for Laboratory Animal Use

Summary of a Workshop

By: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

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Design, Implementation, Monitoring, and Sharing of Performance Standards for Laboratory Animal Use

Summary of a Workshop

By: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

In order to better understand the critical issues pertaining to the concept of performance standards for laboratory animal use, the Institute for Laboratory Animal Research Roundtable on Science and Welfare in Laboratory Animal Use held a public workshop on April 20-21, 2015. The purpose of the workshop was to promote the appropriate and responsible care of animals in research, to provide a balanced and civil forum for discussion and collaboration, and to help build transparency and trust among stakeholders. Participants addressed the challenges of defining, developing, implementing, assessing, and validating performance standards to ensure "optimal practices, management, and operations." This report summarizes the presentations and discussions from the workshop.

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161

Publisher

National Academies Press

Published Date

ISBN 10

030937927X

ISBN 13

9780309379274

Occupational Health and Safety in the Care and Use of Research Animals

By: Committee on Occupational Safety and Health in Research Animal Facilities,Institute for Laboratory Animal Research,Commission on Life Sciences,National Research Council

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Occupational Health and Safety in the Care and Use of Research Animals

By: Committee on Occupational Safety and Health in Research Animal Facilities,Institute for Laboratory Animal Research,Commission on Life Sciences,National Research Council

Much has been written about the care of research animals. Yet little guidance has appeared on protecting the health and safety of the people who care for or use these animals. This book, an implementation handbook and companion to Guide For the Care and Use of Laboratory Animals, identifies principles for building a program and discusses the accountability of institutional leaders, managers, and employees for a program's success. It provides a detailed description of risks-- physical and chemical hazards, allergens and zoonoses, and hazards from experiments--which will serve as a continuing reference for the laboratory. The book offers specific recommendations for controlling risk through administrative procedures, facility design, engineering controls, and periodic evaluations. The volume focuses on the worker, with detailed discussions of work practices, the use of personal protective gear, and the development of an emergency response plan. This handbook will be invaluable to administrators, researchers, and employees in any animal research facility. It will also be of interest to personnel in zoos, animal shelters, and veterinary facilities.

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Page Count

167

Publisher

National Academies Press

Published Date

ISBN 10

0309520398

ISBN 13

9780309520393

Guide for the Care and Use of Laboratory Animals

Eighth Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals

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Guide for the Care and Use of Laboratory Animals

Eighth Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals

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246

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National Academies Press

Published Date

ISBN 10

0309154006

ISBN 13

9780309154000

Rodents

By: Committee on Rodents,Institute for Laboratory Animal Research,Commission on Life Sciences,National Research Council

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Rodents

By: Committee on Rodents,Institute for Laboratory Animal Research,Commission on Life Sciences,National Research Council

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180

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National Academies Press

Published Date

ISBN 10

0309585775

ISBN 13

9780309585774

Companion Guide to Infectious Diseases of Mice and Rats

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats

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Companion Guide to Infectious Diseases of Mice and Rats

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats

This companion to Infectious Diseases of Mice and Rats makes practical information on rodent diseases readily accessible to researchers. This volume parallels the three parts of the main volume. Part I, Principles of Rodent Disease Prevention, briefly examines the requirements for maintaining pathogen-free rodents, factors in designing health surveillance programs, and other laboratory management issues. Part II, Disease Agents, is an easy-to-use reference section, listing diagnosis and control methods, the potential for interference with research, and other factors for disease agents ranging from adenoviruses to tapeworms. It covers bacteria, viruses, fungi and common ectoparasites, and endoparasites. Part III, Diagnostic Indexes, presents alphabetical listings of clinical signs, pathology, and research complications and lists infectious agents that might be responsible for each.

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Page Count

106

Publisher

National Academies Press

Published Date

ISBN 10

0309042836

ISBN 13

9780309042833

Infectious Diseases of Mice and Rats

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats

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Infectious Diseases of Mice and Rats

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats

This new editionâ€"a must for all researchers who use these lab animalsâ€"provides practical suggestions for breeding, keeping, and identifying pathogen-free laboratory rodents. It contains three informative sections. The first, Principles of Rodent Disease Prevention, summarizes methods for eliminating infectious agents. It offers information on pathogen terminology; pathogen status of rodents; and breeding, transporting, isolating, testing, and diagnosing rodents. The second section, Individual Disease Agents and Their Effects on Research, describes the diagnosis and control of each infectious agent, and the last section, Diagnostic Indexes: Clinical Signs, Pathology, and Research Complications, contains informative tables covering all the diseases listed in the volume, arranged to help in the diagnosis of infected animals.

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Page Count

410

Publisher

National Academies Press

Published Date

ISBN 10

0309063329

ISBN 13

9780309063326

Use of Laboratory Animals in Biomedical and Behavioral Research

By: National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research

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Use of Laboratory Animals in Biomedical and Behavioral Research

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

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Page Count

113

Publisher

National Academies Press

Published Date

ISBN 10

0309038391

ISBN 13

9780309038393

Book's by Institute of Laboratory Animal Resources

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals -- Korean Edition

Guide for the Care and Use of Laboratory Animals -- Korean Edition

Laboratory Animal Management

Laboratory Animal Management

Rodents

Rodents

Guide for the Care and Use of Laboratory Animals -- Japanese Edition

Guide for the Care and Use of Laboratory Animals -- Japanese Edition

Transportation of Laboratory Animals

Transportation of Laboratory Animals

Education and Training in the Care and Use of Laboratory Animals

Education and Training in the Care and Use of Laboratory Animals

The Development of Science-based Guidelines for Laboratory Animal Care

The Development of Science-based Guidelines for Laboratory Animal Care

Design, Implementation, Monitoring, and Sharing of Performance Standards for Laboratory Animal Use

Design, Implementation, Monitoring, and Sharing of Performance Standards for Laboratory Animal Use

Occupational Health and Safety in the Care and Use of Research Animals

Occupational Health and Safety in the Care and Use of Research Animals

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals

Rodents

Rodents

Companion Guide to Infectious Diseases of Mice and Rats

Companion Guide to Infectious Diseases of Mice and Rats

Infectious Diseases of Mice and Rats

Infectious Diseases of Mice and Rats

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research

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