Immunization Safety Review Committee's Books

Immunization Safety Review

SV40 Contamination of Polio Vaccine and Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Immunization Safety Review

SV40 Contamination of Polio Vaccine and Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.

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Page Count

118

Publisher

National Academies Press

Published Date

ISBN 10

0309086108

ISBN 13

9780309086103

Immunization Safety Review

SV40 Contamination of Polio Vaccine and Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Immunization Safety Review

SV40 Contamination of Polio Vaccine and Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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118

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National Academies Press

Published Date

ISBN 10

0309168910

ISBN 13

9780309168915

Immunization Safety Review

Thimerosal-Containing Vaccines and Neurodevelopmental Disorders

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Immunization Safety Review

Thimerosal-Containing Vaccines and Neurodevelopmental Disorders

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

In this report, the Immunization Safety Review committee examines the hypothesis of whether or not the use of vaccines containing the preservative thimerosal can cause neurodevelopmental disorders (NDDs), specifically autism, attention deficit/hyperactivity disorder (ADHD), and speech or language delay.

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Page Count

137

Publisher

National Academies Press

Published Date

ISBN 10

0309170370

ISBN 13

9780309170376

Immunization Safety Review

Influenza Vaccines and Neurological Complications

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Immunization Safety Review

Influenza Vaccines and Neurological Complications

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

Infection with the influenza virus can have a serious effect on the health of people of all ages, although it is particularly worrisome for infants, the elderly, and people with underlying heart or lung problems. A vaccine exists (the "flu" shot) that can greatly decrease the impact of influenza. Because the strains of virus that are expected to cause serious illness and death are slightly different every year, the vaccine is also slightly different every year and it must be given every year, unlike other vaccines. The Immunization Safety Review committee reviewed the data on influenza vaccine and neurological conditions and concluded that the evidence favored rejection of a causal relationship between influenza vaccines and exacerbation of multiple sclerosis. For the other neurological conditions studied, the committee concluded the evidence about the effects of influenza vaccine is inadequate to accept or reject a causal relationship. The committee also reviewed theories on how the influenza vaccine could damage the nervous system. The evidence was at most weak that the vaccine could act in humans in ways that could lead to these neurological problems.

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Page Count

190

Publisher

National Academies Press

Published Date

ISBN 10

0309090865

ISBN 13

9780309090865

Immunization Safety Review

SV40 Contamination of Polio Vaccine and Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Immunization Safety Review

SV40 Contamination of Polio Vaccine and Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Page Count

118

Publisher

National Academies Press

Published Date

ISBN 10

0309086108

ISBN 13

9780309086103

Immunization Safety Review

Multiple Immunizations and Immune Dysfunction

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Immunization Safety Review

Multiple Immunizations and Immune Dysfunction

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

By two years of age, healthy infants in the United States can receive up to 20 vaccinations to protect against 11 diseases. Although most people know that vaccines effectively protect against serious infectious diseases, approximately one-quarter of parents in a recent survey believe that infants get more vaccines than are good for them, and that too many immunizations could overwhelm an infant's immune system. The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction. Specifically, the committee looked at evidence of potential biological mechanisms and at epidemiological evidence for or against causality related to risk for infections, the autoimmune disease type 1 diabetes, and allergic disorders.

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Page Count

304

Publisher

National Academies Press

Published Date

ISBN 10

0309169887

ISBN 13

9780309169882

Vaccine Safety Research, Data Access, and Public Trust

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on the Review of the National Immunization Program's Research Procedures and Data Sharing Program

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Vaccine Safety Research, Data Access, and Public Trust

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on the Review of the National Immunization Program's Research Procedures and Data Sharing Program

The Vaccine Safety Datalink (VSD) is a large, linked database of patient information that was developed jointly by CDC and several private managed care organizations in 1991. It includes data on vaccination histories, health outcomes, and characteristics of more than 7 million patients of eight participating health organizations. Researchers from CDC and the managed care groups have used VSD information to study whether health problems are associated with vaccinations. The subsequent VSD data sharing program was launched in 2002 to allow independent, external researchers access to information in the database. In this report, the committee that was asked to review aspects of this program recommends that two new oversight groups are needed to ensure that the policies and procedures of the VSD and its data sharing program are implemented as fairly and openly as possible.

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Page Count

152

Publisher

National Academies Press

Published Date

ISBN 10

0309165245

ISBN 13

9780309165242

Immunization Safety Review

Thimerosal - Containing Vaccines and Neurodevelopmental Disorders

By: Immunization Safety Review Committee,Board on Health Promotion and Disease Prevention,Institute of Medicine

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Immunization Safety Review

Thimerosal - Containing Vaccines and Neurodevelopmental Disorders

By: Immunization Safety Review Committee,Board on Health Promotion and Disease Prevention,Institute of Medicine

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Page Count

105

Publisher

National Academies Press

Published Date

ISBN 10

0309090083

ISBN 13

9780309090087

Immunization Safety Review

Hepatitis B Vaccine and Demyelinating Neurological Disorders

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

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Immunization Safety Review

Hepatitis B Vaccine and Demyelinating Neurological Disorders

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

Immunization to protect infants and children from vaccine-preventable diseases is one of the greatest achievements of public health. Immunization is not without risks, however. It is well established, for example, that the oral polio vaccine can on rare occasion cause paralytic polio. The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the available evidence on a series of immunization safety concerns. The committee is charged with examining three immunization safety hypotheses each year during the three-year study period (2001- 2003). While all of the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. In this report, which is the fourth in the series, the committee examines the hypothesis that the hepatitis B vaccine increases the risk for demyelinating disorders of the central or peripheral nervous systems, including multiple sclerosis (MS) and Guillain-Barré syndrome (GBS).

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Page Count

120

Publisher

National Academies Press

Published Date

ISBN 10

0309084695

ISBN 13

9780309084697

Canadian Immunization Guide

By: Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization

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Canadian Immunization Guide

By: Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

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392

Published Date

ISBN 10

0660193922

ISBN 13

9780660193922

Immunization Safety Review

Influenza Vaccines and Neurological Complications

By: Immunization Safety Review Committee,Board on Health Promotion and Disease Prevention,Institute of Medicine

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Immunization Safety Review

Influenza Vaccines and Neurological Complications

By: Immunization Safety Review Committee,Board on Health Promotion and Disease Prevention,Institute of Medicine

Infection with the influenza virus can have a serious effect on the health of people of all ages, although it is particularly worrisome for infants, the elderly, and people with underlying heart or lung problems. A vaccine exists (the â€œfluâ€ shot) that can greatly decrease the impact of influenza. Because the strains of virus that are expected to cause serious illness and death are slightly different every year, the vaccine is also slightly different every year and it must be given every year, unlike other vaccines. The Immunization Safety Review committee reviewed the data on influenza vaccine and neurological conditions and concluded that the evidence favored rejection of a causal relationship between influenza vaccines and exacerbation of multiple sclerosis. For the other neurological conditions studied, the committee concluded the evidence about the effects of influenza vaccine is inadequate to accept or reject a causal relationship. The committee also reviewed theories on how the influenza vaccine could damage the nervous system. The evidence was at most weak that the vaccine could act in humans in ways that could lead to these neurological problems.

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Page Count

190

Publisher

National Academies Press

Published Date

ISBN 10

0309388015

ISBN 13

9780309388016

The Childhood Immunization Schedule and Safety

Stakeholder Concerns, Scientific Evidence, and Future Studies

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Assessment of Studies of Health Outcomes Related to the Recommended Childhood Immunization Schedule

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The Childhood Immunization Schedule and Safety

Stakeholder Concerns, Scientific Evidence, and Future Studies

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Assessment of Studies of Health Outcomes Related to the Recommended Childhood Immunization Schedule

Vaccines are among the most safe and effective public health interventions to prevent serious disease and death. Because of the success of vaccines, most Americans today have no firsthand experience with such devastating illnesses as polio or diphtheria. Health care providers who vaccinate young children follow a schedule prepared by the U.S. Advisory Committee on Immunization Practices. Under the current schedule, children younger than six may receive as many as 24 immunizations by their second birthday. New vaccines undergo rigorous testing prior to receiving FDA approval; however, like all medicines and medical interventions, vaccines carry some risk. Driven largely by concerns about potential side effects, there has been a shift in some parents' attitudes toward the child immunization schedule. The Childhood Immunization Schedule and Safety identifies research approaches, methodologies, and study designs that could address questions about the safety of the current schedule. This report is the most comprehensive examination of the immunization schedule to date. The IOM authoring committee uncovered no evidence of major safety concerns associated with adherence to the childhood immunization schedule. Should signals arise that there may be need for investigation, however, the report offers a framework for conducting safety research using existing or new data collection systems.

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Age

Page Count

237

Publisher

National Academies Press

Published Date

ISBN 10

0309267056

ISBN 13

9780309267052

Book's by Immunization Safety Review Committee

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Vaccine Safety Research, Data Access, and Public Trust

Vaccine Safety Research, Data Access, and Public Trust

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Immunization Safety Review

Canadian Immunization Guide

Canadian Immunization Guide

Immunization Safety Review

Immunization Safety Review

The Childhood Immunization Schedule and Safety

The Childhood Immunization Schedule and Safety

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