Bioinformatics encompasses a broad and ever-changing range of activities involved with the management and analysis of data from molecular biology experiments. Despite the diversity of activities and applications, the basic methodology and core tools needed to tackle bioinformatics problems is common to many projects. This unique book provides an invaluable introduction to three of the main tools used in the development of bioinformatics software - Perl, R and MySQL - and explains how these can be used together to tackle the complex data-driven challenges that typify modern biology. These industry standard open source tools form the core of many bioinformatics projects, both in academia and industry. The methodologies introduced are platform independent, and all the examples that feature have been tested on Windows, Linux and Mac OS. Building Bioinformatics Solutions is suitable for graduate students and researchers in the life sciences who wish to automate analyses or create their own databases and web-based tools. No prior knowledge of software development is assumed. Having worked through the book, the reader should have the necessary core skills to develop computational solutions for their specific research programmes. The book will also help the reader overcome the inertia associated with penetrating this field, and provide them with the confidence and understanding required to go on to develop more advanced bioinformatics skills.
Covers the operations of a leading SS Calvary Regiment and describes fighting under desperate conditions on the Eastern Front. Formed in 1942 8th SS Cavalry Division Florian Geyer was soon deployed to the Eastern Front where Hitler’s ambition to conquer Russia was stalling badly. In common with other SS units the Division was responsible for razing towns and villages, poisoning wells and genocide often against unarmed civilians. This scorched earth policy was aimed at hindering the Red Army’s advance. After moving South, the Division took part in the retreat from the Dnieper River before operating in Hungary and Croatia. The end came when trapped in Budapest by Soviet and Romanian forces, the Division was destroyed in December 1944. By the end of the siege only 800 of the 30,000 men in the SS Corps reached German lines. Using many startling contemporary images, this latest book in the Author’s Images of War series vividly illustrates the horror of warfare on the Eastern Front.
The first comprehensive biography of the godfather of Australian bushranging – Frank Gardiner – leader of the Lachlan gang and mastermind of the largest gold heist in Australian history. Atop the hierarchy of Australian bushrangers sits Ned Kelly – the ultimate outlaw – and just below him, the tragic figure of Ben Hall, who joined a gang led by a man whose name today is less well known, but in his time was much more famous than any other: Frank Gardiner. Mastermind of the largest gold robbery in Australia’s history, Gardiner led an extraordinary life, the full telling of which is long overdue. In a tough country and among a group of tough men, Gardiner was the toughest of them all. But while he engaged in gunfights with police to evade capture, he was always courteous and could lay claim to never killing anyone, and never stole from those who couldn't afford to be robbed. He went by three different surnames in his lifetime and spent almost half of it behind bars, including at some of the colonies' most notorious penal institutions: the Pentridge Stockade, Cockatoo Island and Darlinghurst Gaol. But if Gardiner was never quite the Robin Hood he sometimes imagined himself to be, he was nevertheless a natural leader, and a man capable of inspiring a motley bunch of stockmen and drifters to become the most effective and successful bushranging gang in the country’s history. His Lachlan gang operated with a clockwork efficiency that culminated in the robbery of the Gold Escort at Eugowra Rocks, and from 1861 to 1863 it held reign over the roads of the Western Plains of New South Wales. Richly detailed, The Golden Gang shines a new light onto Gardiner's remarkable life – one that ended in shocking tragedy – and reinstates him in the pantheon of Australian outlaw heroes.
The past, present, and future role of global migration Throughout history, migrants have fueled the engine of human progress. Their movement has sparked innovation, spread ideas, relieved poverty, and laid the foundations for a global economy. In a world more interconnected than ever before, the number of people with the means and motivation to migrate will only increase. Exceptional People provides a long-term and global perspective on the implications and policy options for societies the world over. Challenging the received wisdom that a dramatic growth in migration is undesirable, the book proposes new approaches for governance that will embrace this international mobility. The authors explore the critical role of human migration since humans first departed Africa some fifty thousand years ago—how the circulation of ideas and technologies has benefited communities and how the movement of people across oceans and continents has fueled economies. They show that migrants in today's world connect markets, fill labor gaps, and enrich social diversity. Migration also allows individuals to escape destitution, human rights abuses, and repressive regimes. However, the authors indicate that most current migration policies are based on misconceptions and fears about migration's long-term contributions and social dynamics. Future policies, for good or ill, will dramatically determine whether societies can effectively reap migration's opportunities while managing the risks of the twenty-first century. A guide to vigorous debate and action, Exceptional People charts the past and present of international migration and makes practical recommendations that will allow everyone to benefit from its unstoppable future growth.
The planning for the raising of what was to become 16th (Service) Battalion, Northumberland Fusiliers, started within two days of the outbreak of the war. The initial efforts took on a more professional look within a month, when the Newcastle Chambers of Commerce set about raising money and aiming to raise several battalions in response to Lord Kitchener's call for men. The outcome was a Pals battalion, the 1st Newcastle Commercials. Arriving in France at the end of 1915, the battalion, like so many others of its type, had its first experience of a major action on the Somme on 1st July 1916, in its case in the forlorn attempt to capture the German front line village of Thiepval. The outcome is well known; a disaster that ravaged the battalion's ranks. However, the battalion was reinforced, reorganized, and took its part in actions at Ovillers and along the Ancre as the battle grinder on over the next four and a half months. In 1917 it was involved in the advance on the Hindenburg Line and was then transferred to the North Sea coast, with the intention of taking part in the daring plan to launch a major amphibious landing behind the German lines in the summer. This was thwarted by a masterly pre-emptive German counter stroke. By the end of the year the battalion was engaged in operations in the northern part of the Salient after the Battle of Third Ypres (Passchendaele) had formally ended. In early February 1918 the battalion was disbanded as part of a general reorganization of the BEF, which saw divisions losing three of their twelve infantry battalions. In outline it is a common story; but, as for all the Pals battalions, its unusual origins and its very close connection to a local area, in this case Newcastle, provides an enduring fascination for today's generation. Ian Johnson has worked extraordinarily hard to gather documents from members of the battalion - letters, diaries, and recollections - as well as numerous photographs. He has prepared extensive appendices on its membership and its casualties. The outcome is a fitting tribute to these young men from Newcastle men of a century ago who, for whatever motive, answered their country's call, all too many of whom paid for it with their lives or their health.
* Each location is presented on facing pages where possible, so that text and maps can be read without turning pages * Photography has been taken in conditions and standards that walkers and riders will experience along the routes * Most of the routes chosen do not require specialist navigation or bushcraft skills For the first time in a single volume, this book brings together more than 140 of the best walks, tracks or trails in New South Wales, which can be walked by the moderately fit individual. They are located in national parks, coastal parks, state forests, conservation reserves, historic parks and local government and public easements. Other routes follow state highways, minor roads, coastal cliffs, old gold routes, or pass bushranger haunts and back roads linking towns and historical features. Most routes do not require specialist navigation or bushcraft skills, and vary in length from a 45-minute stroll to a 4-day, 65-kilometre camping trip. Walks, Tracks and Trails of New South Wales highlights the best the state has to offer, from an outback ghost town and ancient lake beds, to Australia's highest mountain, coastal environments and World Heritage rainforests. Easy-to-interpret maps are included to help you navigate, and the book's size makes it convenient to bring with you on your adventures.
Bioinformatics encompasses a broad and ever-changing range of activities involved with the management and analysis of data from molecular biology experiments. Despite the diversity of activities and applications, the basic methodology and core tools needed to tackle bioinformatics problems is common to many projects. This unique book provides an invaluable introduction to three of the main tools used in the development of bioinformatics software - Perl, R and MySQL - and explains how these can be used together to tackle the complex data-driven challenges that typify modern biology. These industry standard open source tools form the core of many bioinformatics projects, both in academia and industry. The methodologies introduced are platform independent, and all the examples that feature have been tested on Windows, Linux and Mac OS. Building Bioinformatics Solutions is suitable for graduate students and researchers in the life sciences who wish to automate analyses or create their own databases and web-based tools. No prior knowledge of software development is assumed. Having worked through the book, the reader should have the necessary core skills to develop computational solutions for their specific research programmes. The book will also help the reader overcome the inertia associated with penetrating this field, and provide them with the confidence and understanding required to go on to develop more advanced bioinformatics skills.
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