Talk is a central activity in social life. But how is ordinary talk organized? How do people coordinate their talk in interaction? And what is the role of talk in wider social processes? Conversation Analysis has developed over the past forty years as a key method for studying social interaction and language use. Its unique perspective and systematic methods make it attractive to an interdisciplinary audience. In this second edition of their highly acclaimed introduction, Ian Hutchby and Robin Wooffitt offer a wide-ranging and accessible overview of key issues in the field. The second edition has been substantially revised to incorporate recent developments, including an entirely new final chapter exploring the contribution of Conversation Analysis to key issues in social science. The book provides a grounding in the theory and methods of Conversation Analysis, and demonstrates its procedures by analyzing a variety of concrete examples. Written in a lively and engaging style, Conversation Analysis has become indispensable reading for students and researchers in sociology, sociolinguistics, applied linguistics, social psychology, communication studies and anthropology.
Nine months after the explosion, a French expedition searching for signs of life discovered a single spider that had crossed to the island on a balloon of silk. Life had returned to Krakatau. Scientists have been studying the island ever since.
This multidisciplinary book focuses on the relationships and interactions between palaeobiogeography, biogeography, dispersal, vicariance, migrations and evolution of organisms in the SE Asia-Australasian region. The book investigates biogeographic links between SE Asia and Australasia which go back more than 500 million years. It also focuses on the links between geological evolution and biological migrations and evolution in the region. It was in the SE Asian region that Alfred Russell Wallace established his biogeographic line, now known as Wallace's Line, which was the beginning of biogeography. Wallace also independently developed his theory of evolution based on his work in this area.;The book brings together, for the first time, geologists, palaeontologists, zoologists, botanists, entomologists, evolutionary biologists and archaeologists, in the one volume, to relate the region's geological past to its present biological peculiarities. The book is organized into six sections. Section 1 Paleobiogeographic Background provides overviews of the geological and tectonic evolution of SE Asia-Australasia, and changing patterns of land and sea for the last 540 million years. Section 2 Palaeozoic and Mesozoic Geology and Biogeography discusses Palaeozoic and Mesozoic biogeography of conodonts, brachiopods, plants, dinosaurs and radiolarians and the recognition of ancient biogeographic boundaries or Wallace Lines in the region. Section 3 Wallace's Line focuses on the biogeographic boundary established by Wallace, including the history of its establishment, its significance to biogeography in general and its applicability in the context of modern biogeography.;Section 4 Plant biogeography and evolution includes discussion on primitive angiosperms, the diaspora of the southern rushes, and environmental, climatic and evolutionary implications of plants and palynomorphs in the region. The biogeography and migration of insects, butterflies, birds, rodents and other non-primate mammals is discussed in section 5, Non Primates. The final section 6 Primates focuses on the biogeographic radiation, migration and evolution of primates and includes papers on the occurrence and migration of early hominids and the requirements for human colonization of Australia.
Don't be mixed up about chemistry! Simplify the complex chemical reactions that take place everywhere in our lives with this engaging, easy-to-follow, question-and-answer guide! Where would we be without atoms and compounds? Gas, liquids, solids, and plasma? Acids and bases? Bonds and reactions? Matter and energy? The Handy Chemistry Answer Book covers the building blocks of life and the universe. The secret life of atoms, how polar bears aren’t actually white, why oil and water don't mix, and much, much more are revealed and explained. This informative guide covers the basics of chemistry (history, atomic structures, chemical bonds and reactions, organic and inorganic chemistry) to more advanced material (nuclear chemistry, biochemistry, physical and theoretical chemistry) by answering nearly 1,000 common chemistry questions, including ... What causes lightning? How does photosynthesis work? What are hard and soft Lewis acids and bases? What makes a fabric “waterproof”? What are the twelve principles of green chemistry? When did alchemists finally abandon trying to make gold? What is Le Chatelier’s principle? What do the different octane ratings mean at the gas pump? What is genetic engineering? Why is calcium important for strong bones? What is the 18-electron rule? Why does chocolate turn white as it ages? Chemical reactions that rule the world; their properties, structure, composition, behavior, and history are tackled and explained in plain English in The Handy Chemistry Answer Book. With many photos, illustrations, a few formulas, molecular diagrams, and other graphics, this fun, fact-filled tome is richly illustrated. A history of chemistry timeline, appendices on Nobel Prize in Chemistry winners, a bibliography, further reading section, glossary of terms, a table of physical constants, a table of conversion factors, and extensive index add to its usefulness.
Drawing on a wide variety of empirical methodologies, including large-scale survey analysis, survey experiments, and content analyses, Following the Ticker explores the complex relationship between stock market performance and political judgments through distinctive patterns of coverage in American news media. Building an eclectic theory that explores the interplay between media agenda-setting and partisan motivated reasoning, author Ian G. Anson helps to explain why the stock market increasingly occupies the minds of Americans when they evaluate the performance of incumbent presidents. In doing so, Following the Ticker contributes to a growing literature exploring the links between public opinion and economic inequality in American society. Because "the stock market is not the economy," the increasing salience of the stock market as a source of political judgments reflects a worrying development for classic models of democratic accountability.
Principles of Legislative and Regulatory Drafting provides a succinct guide to an area of law and practice which has previously been poorly served by English textbooks. It explains how drafters can convert legislative and regulatory policy into a form which has the desired effect in the most direct and accessible way. On the basis that those who seek to communicate must be conscious of how their words will be read, it includes a chapter on interpretation. Other chapters include the nature of drafting instructions (including ethical considerations), the general principles of drafting, the protection of human rights, the creation of statutory corporations and schemes of licensing, subordinate legislation, and the creation of criminal offences. The principles and skills of drafting are very largely common to both the legislative and regulatory fields, but the book draws attention to areas in which significant differences arise. Extracts from the Interpretation Act 1978 and the European Convention on Human Rights are included as Appendices. The book provides an invaluable introduction for those engaged in legislative and regulatory drafting, while also being useful to anyone who is interested in the creation and interpretation of legislative and regulatory texts.
It was 1862, the second year of the Civil War, though Kansans and Missourians had been fighting over slavery for almost a decade. For the 250 Union soldiers facing down rebel irregulars on Enoch Toothman’s farm near Butler, Missouri, this was no battle over abstract principles. These were men of the First Kansas Colored Infantry, and they were fighting for their own freedom and that of their families. They belonged to the first black regiment raised in a northern state, and the first black unit to see combat during the Civil War. Soldiers in the Army of Freedom is the first published account of this largely forgotten regiment and, in particular, its contribution to Union victory in the trans-Mississippi theater of the Civil War. As such, it restores the First Kansas Colored Infantry to its rightful place in American history. Composed primarily of former slaves, the First Kansas Colored saw major combat in Missouri, Indian Territory, and Arkansas. Ian Michael Spurgeon draws upon a wealth of little-known sources—including soldiers’ pension applications—to chart the intersection of race and military service, and to reveal the regiment’s role in countering white prejudices by defying stereotypes. Despite naysayers’ bigoted predictions—and a merciless slaughter at the Battle of Poison Spring—these black soldiers proved themselves as capable as their white counterparts, and so helped shape the evolving attitudes of leading politicians, such as Kansas senator James Henry Lane and President Abraham Lincoln. A long-overdue reconstruction of the regiment’s remarkable combat record, Spurgeon’s book brings to life the men of the First Kansas Colored Infantry in their doubly desperate battle against the Confederate forces and skepticism within Union ranks.
“A hot-rod joy ride through mid-20th-century American history” (The New York Times Book Review), this one-of-a-kind narrative masterfully recreates the rivalry between the two men who innovated the electric guitar’s amplified sound—Leo Fender and Les Paul—and their intense competition to convince rock stars like the Beatles, Jimi Hendrix, and Eric Clapton to play the instruments they built. In the years after World War II, music was evolving from big-band jazz into rock ’n’ roll—and these louder styles demanded revolutionary instruments. When Leo Fender’s tiny firm marketed the first solid-body electric guitar, the Esquire, musicians immediately saw its appeal. Not to be out-maneuvered, Gibson, the largest guitar manufacturer, raced to build a competitive product. The company designed an “axe” that would make Fender’s Esquire look cheap and convinced Les Paul—whose endorsement Leo Fender had sought—to put his name on it. Thus was born the guitar world’s most heated rivalry: Gibson versus Fender, Les versus Leo. While Fender was a quiet, half-blind, self-taught radio repairman, Paul was a brilliant but headstrong pop star and guitarist who spent years toying with new musical technologies. Their contest turned into an arms race as the most inventive musicians of the 1950s and 1960s—including bluesman Muddy Waters, rocker Buddy Holly, the Beatles, Bob Dylan, and Eric Clapton—adopted one maker’s guitar or another. By 1969 it was clear that these new electric instruments had launched music into a radical new age, empowering artists with a vibrancy and volume never before attainable. In “an excellent dual portrait” (The Wall Street Journal), Ian S. Port tells the full story in The Birth of Loud, offering “spot-on human characterizations, and erotic paeans to the bodies of guitars” (The Atlantic). “The story of these instruments is the story of America in the postwar era: loud, cocky, brash, aggressively new” (The Washington Post).
Marine Mammal Observer and Passive Acoustic Monitoring Handbook is the ultimate instruction manual for mitigation measures to minimise man-made acoustical and physical disturbances to marine mammals from industrial and defence activities.
Nutrition, Toxicity, and Cancer provides practical guidance on methodology for formulating diets and designing nutritional studies in animals and humans, in addition to valuable information on how nutrition influences specific biological processes such as biotransformation of foreign and endogenously produced compounds. The book also presents sample diets and advice on the layout of metabolic suites. Other topics discussed include the complex interactions between nutrition and carcinogenic processes, teratogenesis and mutagenesis. Toxicologists, cancer researchers, nutritionists, and biochemists should consider Nutrition, Toxicity, and Cancer to be an invaluable reference resource that provides up-to-date reviews on the effect of diet on mammalian and microbial metabolic processes in the body.
From the international bestselling author of Dracul comes the authoritative sequel to Bram Stoker’s original horror classic. London, 1912. A quarter of a century after Count Dracula “crumbled into dust,” Quincey Harker—the son of Jonathan and Mina Harker—leaves law school to pursue a career on stage, only to stumble upon the troubled production of Dracula, directed and produced by Bram Stoker himself. As the play plunges Quincey into the world of his parents' terrible secrets, death begins to stalk the original band of heroes that defeated Dracula a quarter-century ago. Could it be that the count survived and is now seeking revenge? Or is there another, far more sinister force at work whose relentless purpose is to destroy anything and anyone associated with Dracula, the most notorious vampire of all time... Dracula the Un-Dead is the true sequel to Bram Stoker’s classic novel, written by his direct descendant and a well-known Dracula historian. Dracula the Un-Dead provides answers to all the questions that the original novel left unexplained, as well as new insights into the world of iniquity and fear lurking just beneath the surface of polite Victorian England.
This book addresses key issues related to teaching pupils from disadvantaged and impoverished backgrounds and provides a valuable reference and pedagogical tool for teachers and teacher educators. Research has consistently shown that the most economically disadvantaged pupils have the poorest educational outcomes. Austerity government policies and pressures of performativity on schools may have exacerbated this inequality. Yet many teachers remain ill-informed about the effects of social disadvantage on students’ learning and consequently are ill-prepared in appropriate teaching methods. The text critically examines the lessons from previous policy and practice, discusses cognitive and affective aspects of school learning for disadvantaged children and explores the pedagogic implications of research evidence. Using insights from existing research, the book examines the reasons why some trainees and teachers lack a critical perspective on the contexts of poverty and may hold deficit views of students in poverty that suggests they are unable to learn and need to be controlled. It explains some of the links between poverty, special needs, literacy and educational achievement and focuses on strategies for improvement.
A biography—thoughtful and playful—of the man who founded New Directions and transformed American publishing James Laughlin—poet, publisher, world-class skier—was the man behind some of the most daring, revolutionary works in verse and prose of the twentieth century. As the founder of New Directions, he published Ezra Pound's The Cantos and William Carlos Williams's Paterson; he brought Hermann Hesse and Jorge Luis Borges to an American audience. Throughout his life, this tall, charismatic intellectual, athlete, and entrepreneur preferred to stay hidden. But no longer—in "Literchoor Is My Beat": A Life of James Laughlin, Publisher of New Directions, Ian S. MacNiven has given us a sensitive and revealing portrait of this visionary and the understory of the last century of American letters. Laughlin—or J, as MacNiven calls him—emerges as an impressive and complex figure: energetic, idealistic, and hardworking, but also plagued by doubts—not about his ability to identify and nurture talent but about his own worth as a writer. Haunted by his father's struggles with bipolar disorder, J threw himself into a flurry of activity, pulling together the first New Directions anthology before he'd graduated from Harvard and purchasing and managing a ski resort in Utah. MacNiven's portrait is comprehensive and vital, spiced with Ezra Pound's eccentric letters, J's romantic foibles, and anecdotes from a seat-of-your-pants era of publishing now gone by. A story about the struggle to publish only the best, it is itself an example of literary biography at its finest.
This book assembles a wide range of explanatory perspectives on social inequalities in health. Everywhere in the world, those with less advantage die younger and suffer more illness than the wealthy. Decades of research have documented this reality and yet we lack a comprehensive understanding of the mechanisms through which social circumstances ultimately influence the biological processes that lead to disease. Explanations have been proposed from various disciplines – economics, psychology, behavioral science, geography, and neuroscience – and each sheds light on parts of the overall process. But very few texts assemble these insights into an overall explanatory paradigm. Through a review of concepts and theories from a wide range of disciplines, the author outlines how these may be woven together to offer a more complete picture of how social influences 'get under the skin' to affect health and disease. As well as understanding individual health, the book assembles explanations for social disparities in health. It concludes with a proposal for a set of explanatory models that cross disciplinary boundaries. Topics explored include: Social Inequalities in Health Explanation and Causal Models for Social Epidemiology Social and Economic Theories to Explain Patterns of Disease Biological Pathways Linking Social Determinants to Health Theoretical Models of Health Behavior Work Environment and Health Social Networks, Social Support and Health Positive Influences on Health: Coping and Control The Relationship Between Personality and Health Understanding Health Determinants: Explanatory Theories for Social Epidemiology is a textbook for graduate students in epidemiology, health sciences, health policy, and psychology, as well as social science students who are studying health. It will also be of interest to general readers, and can serve as a reference for researchers in epidemiology and the health sciences who are planning studies of the social determinants of health. The book reviews theories that could be tested in such studies.
What makes a winner?Why do some succeed both in life and in business, and others fail? The 'winner effect' is a term used in biology to describe how an animal that has won a few fights against weak opponents is much more likely to win later bouts against stronger contenders. As Ian Robertson reveals, it applies to humans, too. Success changes the chemistry of the brain, making you more focused, smarter, more confident and more aggressive. And the more you win, the more you will go on to win. But the downside is that winning can become physically addictive.By understanding what the mental and physical changes are that take place in the brain of a 'winner', how they happen, and why they affect some people more than others, Robertson explains what makes a winner or a loser - and how we can use the answers to these questions to understand better the behaviour of our business colleagues, employees, family and friends.
While faith in the Enlightenment was waning elsewhere by 1850, at the United States Military Academy at West Point and in the minds of academy graduates serving throughout the country Enlightenment thinking persisted, asserting that war was governable by a grand theory accessible through the study of military science. Officers of the regular army and instructors at the military academy and their political superiors all believed strongly in the possibility of acquiring a perfect knowledge of war through the proper curriculum. A Scientific Way of War analyzes how the doctrine of military science evolved from teaching specific Napoleonic applications to embracing subjects that were useful for war in North America. Drawing from a wide array of materials, Ian C. Hope refutes earlier charges of a lack of professionalization in the antebellum American army and an overreliance on the teachings of Swiss military theorist Antoine de Jomini. Instead, Hope shows that inculcation in West Point’s American military curriculum eventually came to provide the army with an officer corps that shared a common doctrine and common skill in military problem solving. The proliferation of military science ensured that on the eve of the Civil War there existed a distinctly American, and scientific, way of war. Purchase the audio edition.
What makes a winner? Why do some people succeed both in life and in business, and others fail? Why do a few individuals end up supremely powerful, while many remain powerless? The "winner effect" is a term used in biology to describe how an animal that has won a few fights against weak opponents is much more likely to win later bouts against stronger contenders. As Ian Robertson reveals, it applies to humans, too. Success changes the chemistry of the brain, making you more focused, smarter, more confident, and more aggressive. The effect is as strong as any drug. And the more you win, the more you will go on to win. But the downside is that winning can become physically addictive. By understanding what the mental and physical changes are that take place in the brain of a "winner," how they happen, and why they affect some people more than others, Robertson answers the question of why some people attain and then handle success better than others. He explains what makes a winner—or a loser—and how we can use the answers to these questions to understand better the behavior of our business colleagues, family, friends, and ourselves.
For the experienced collector or someone embarking on a new hobby, this newly revised and updated edition of Book Finds reveals the secrets of locating rare and valuable books. Includes information on first editions and reader's copies, auctions and catalogs, avoiding costly and common beginner mistakes, strategies of professional "book scouts," and buying and selling on the Internet.
First Published in 1986, this two-volume set explores the methods of toxicological risk assessment. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for toxicologists and other practitioners in their respective fields.
The reception of the Gospel of Matthew over two millennia: commentary and interpretation Matthew Through the Centuries offers an overview of the reception history of one of the most prominent gospels in Christian worship. Examining the reception of Matthew from the perspectives of a wide range of interpreters—from Origen and Hilary of Poitiers to Mary Cornwallis and Bob Marley—this insightful commentary explains the major trends in the reception of Matthew in various ecclesial, historical, and cultural contexts. Focusing on characteristically Matthean features, detailed chapter-by-chapter commentary highlights diverse receptions and interpretations of the gospel. Broad exploration of areas such as liturgy, literature, drama, film, hymnody, political discourse, and visual art illustrates the enormous impact Matthew continues to have on Judeo-Christian civilization. Known as ‘the Church’s Gospel,’ Matthew’s text has been the subject of apologetic and theological controversy for hundreds of years. It has been seen as justification for political and ecclesial status quo and as a path to radical discipleship. Matthew has influenced divergent political, spiritual, and cultural figures such as Francis of Assisi, John Ruskin, Leo Tolstoy, Dietrich Bonhoeffer, and Mahatma Gandhi. Matthew’s interest in ecclesiology provides early structures of ecclesial life, such as resolution of community disputes, communal prayer, and liturgical prescriptions for the Eucharist and baptism. A significant addition to the acclaimed Blackwell Bible Commentaries series, Matthew Through the Centuries is an indispensable resource for both students and experts in areas including religious and biblical studies, literature, history, politics, and those interested in the influence of the Bible on Western culture.
Dealing With Change Through Information Sculpting looks at information behaviour in relationship creation and breakdown, parenting, starting and ending work, developing sexualities, becoming ill, being a victim of crime, and dying, to show how our we sculpt information solutions that transform our lives and transform ourselves.
The Palgrave Macmillan Law Masters series is a long-running and successful list of titles offering clear, concise and authoritative guides to the main subject areas, written by experienced and respected authors. This ninth edition of Legal Method provides a lively introduction to the nature of the English legal system and its sources, and to the techniques which lawyers use when handling those sources. The text assumes no prior knowledge and makes its content accessible by clarity of expression rather than by dilution of content. In addition to more conventional sources, writers as varied as Jonathan Swift, Alexander Pope and T. S. Eliot are cited. This is an ideal course companion for both law undergraduate and GDL/CPE students. Includes end of chapter summaries and self-test exercises.
A "conductor" based in Philadelphia, Still (1821–1902) helped guide fugitive slaves to safety in the years before the Civil War. He also created this unforgettable history, a collection of carefully preserved letters, newspaper articles, and firsthand accounts about refugees' hardships, narrow escapes, and deadly struggles. Over 50 illustrations. "Highly recommended."— Midwest Book Review.
The focus of the book is monocyclic inorganic ring systems of the p-block elements and the polymers that are, in many cases, derived from them. Bicyclic or polycyclic arrangements are considered when they are closely related to those of monocyclic systems.
Treatment of Skin Disease: Comprehensive Therapeutic Strategies has been thoroughly revised to give you the latest treatment options for dermatologic conditions. Mark G. Lebwohl, Warren R. Heymann, John Berth-Jones, and Ian Coulson present an intuitive and easy-to-use, definitive treatment reference that covers the full range of choices for each condition so that you are prepared even when your patients do not respond to primary or secondary therapies. With new chapters on today’s hot topics-methocillin-resistant staphylococcus aureus, atypical nevi, autoimmune progesterone dermatitis, and more-and new contributions from international experts, you’ll have a global and current perspective on therapeutic options. Offer your patients the full range of choices and be prepared when your patients do not respond to primary or secondary therapies. Offers guidance for even the most difficult clinical problems by including third and fourth line therapies, as well as standard treatments, so you have options to try when all else fails. Features a summary of each treatment strategy along with detailed discussions of treatment choices so that you can apply the in-depth knowledge of the authors and editors. Presents each chapter in a tabular format, with checklists of diagnostic and investigative pearls and color-coded boxed text, for quick at-a-glance summaries of key details. Includes a full-color clinical photograph of each disease to help you diagnose more effectively. Includes access to the full text, Gold Standard drug database, and all the images online-fully searchable-at expertconsult.com. Covers new and more commonly presenting disorders in 12 new chapters on today’s hot topics, such as methocillin-resistant staphylococcus aureus, atypical nevi, autoimmune progesterone dermatitis, and more. Presents up-to-date evidence and the latest treatments to keep you on the cutting edge of practice. Describes global best practice on the treatment of key disorders through new contributions from international experts.
The northern regions of the globe were populated by indigenous peoples long before explorers, gold-diggers, missionaries, bureaucrats and others ‘discovered’ their land. Polar Peoples describes the sometimes catastrophic effect these incomers and the changing world in general have had on native ways of life in this vast geographical area. It also outlines the awakening of native political activism and some of the most important steps taken towards self-determination by the indigenous peoples of the North. Greenland: Emergence of an Inuit Homeland (by Mark Nuttall) Unusual because of Home Rule from Denmark Native Peoples of the Russian Far North (by Nikolai Vakhtin) Little known outside Russia, these minority groups face an uncertain future The Alaska Natives (by Fae L. Korsmo) Highly significant because of the Alaska Native Claims Act The Inuit of Canada (by Ian Creery) Dene and Nunavut claims have been the subject of much political activity in recent months The Saami of Lapland (by Hugh Beach) Currently dealing with many different issues, from the ongoing effects of Chernoby] on their reindeer herds, to the disintegration of the Soviet Union. With each section written by a recognized expert in his or her field, Polar Peoples gives a fascinating look at this politically and environmentally changing area on the roof of the world. Please note that the terminology in the fields of minority rights and indigenous peoples’ rights has changed over time. MRG strives to reflect these changes as well as respect the right to self-identification on the part of minorities and indigenous peoples. At the same time, after over 50 years’ work, we know that our archive is of considerable interest to activists and researchers. Therefore, we make available as much of our back catalogue as possible, while being aware that the language used may not reflect current thinking on these issues.
Beginning in the 1950s, "Euro Horror" movies materialized in astonishing numbers from Italy, Spain, and France and popped up in the US at rural drive-ins and urban grindhouse theaters such as those that once dotted New York's Times Square. Gorier, sexier, and stranger than most American horror films of the time, they were embraced by hardcore fans and denounced by critics as the worst kind of cinematic trash. In this volume, Olney explores some of the most popular genres of Euro Horror cinema—including giallo films, named for the yellow covers of Italian pulp fiction, the S&M horror film, and cannibal and zombie films—and develops a theory that explains their renewed appeal to audiences today.
In civil-rights-era Chicago, a dedicated group of black activists, educators, and organizations employed black public history as more than cultural activism. Their work and vision energized a movement that promoted political progress in the crucial time between World War II and the onset of the Cold War. Ian Rocksborough-Smith’s meticulous research and adept storytelling provide the first in-depth look at how these committed individuals leveraged Chicago’s black public history. Their goal: to engage with the struggle for racial equality. Rocksborough-Smith shows teachers working to advance curriculum reform in public schools, while well-known activists Margaret and Charles Burroughs pushed for greater recognition of black history by founding the DuSable Museum of African American History. Organizations like the Afro-American Heritage Association, meanwhile, used black public history work to connect radical politics and nationalism. Together, these people and their projects advanced important ideas about race, citizenship, education, and intellectual labor that paralleled the shifting terrain of mid-twentieth-century civil rights.
An alternative introduction to cinema, focusing on the stories of 50 key films that consciously questioned the boundaries, challenged the status quo and made shockwaves we are still feeling today.
The analytical toxicologist may be required to detect, identify,and in many cases measure a wide variety of compounds in samplesfrom almost any part of the body or in related materials such asresidues in syringes or in soil. This book gives principles andpractical information on the analysis of drugs and poisons inbiological specimens, particularly clinical and forensic specimens. After providing some background information the book coversaspects of sample collection, transport, storage and disposal, andsample preparation. Analytical techniques - colour tests andspectrophotometry, chromatography and electrophoresis, massspectrometry, and immunoassay – are covered in depth, and achapter is devoted to the analysis of trace elements and toxicmetals. General aspects of method implementation/validation andlaboratory operation are detailed, as is the role of the toxicologylaboratory in validating and monitoring the performance of point ofcare testing (POCT) devices. The book concludes with reviews ofxenobiotic absorption, distribution and metabolism,pharmacokinetics, and general aspects of the interpretation ofanalytical toxicology results. A clearly written, practical, integrated approach to the basicsof analytical toxicology. Focuses on analytical, statistical and pharmacokineticprinciples rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and linksto related sites. Written by an experienced team of authors,Fundamentals ofAnalytical Toxicology is an invaluable resource for thosestarting out in a career in analytical toxicology across a widerange of disciplines including clinical and forensic science, foodsafety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail themany and varied aspects of the science of toxicological analysis.The 17 chapters cover every foreseeable aspect, from specimencollection through analytical techniques and quality control topharmacological principles and interpretation of results. Theauthors bring together a great deal of experience in the field andhave succeeded admirably in achieving their goal: "to giveprinciples and practical information on the analysis of drugs,poisons and other relevant analytes in biological specimens...".The book is very readable and quite up-to-date, and contains manyillustrative figures, charts and tables. Both the student and thepracticing professional would do well to study this materialcarefully, as there is something here for every conceivable levelof interest.” Review from RandallBaselt "This text comes highly recommended for any analyticaltoxicology trainee." The Bulletin of the Royal College ofPathologists “Overall, this book provides a comprehensive, thorough,clear, up to date and practical treatment of analytical toxicologyat a high standard. Understanding of the text is enhanced bythe use of many illustrations. Specifications, guidelines,and methods are highlighted in grey background“Boxes”. The many and up to date literaturereferences in each chapter demonstrate the authors’ thoroughwork and permit easy access to deeper information. Thereforethis book can be highly recommended as a valuable source ofknowledge in analytical toxicology both as an introduction and forthe advanced reader.” GTFCh Bulletin“Toxichem + Krimtech”, May 2008 (translated,original review in German) “Many toxicologists will add this important referenceto their libraries because it competently fills a need...” International Journal of Toxicology “The book is very well illustrated, easy to understandand pleasant to read, and contains a wealth of dedicatedinformation.” International Journal of EnvironmentalAnalytical Chemistry
This fast-paced book by Yale professors Michael Graetz and Ian Shapiro unravels the following mystery: How is it that the estate tax, which has been on the books continuously since 1916 and is paid by only the wealthiest two percent of Americans, was repealed in 2001 with broad bipartisan support? The mystery is all the more striking because the repeal was not done in the dead of night, like a congressional pay raise. It came at the end of a multiyear populist campaign launched by a few individuals, and was heralded by its supporters as a signal achievement for Americans who are committed to the work ethic and the American Dream. Graetz and Shapiro conducted wide-ranging interviews with the relevant players: members of congress, senators, staffers from the key committees and the Bush White House, civil servants, think tank and interest group representatives, and many others. The result is a unique portrait of American politics as viewed through the lens of the death tax repeal saga. Graetz and Shapiro brilliantly illuminate the repeal campaign's many fascinating and unexpected turns--particularly the odd end result whereby the repeal is slated to self-destruct a decade after its passage. They show that the stakes in this fight are exceedingly high; the very survival of the long standing American consensus on progressive taxation is being threatened. Graetz and Shapiro's rich narrative reads more like a political drama than a conventional work of scholarship. Yet every page is suffused by their intimate knowledge of the history of the tax code, the transformation of American conservatism over the past three decades, and the wider political implications of battles over tax policy.
What motivates people to care about others is a fundamental question in the social and cognitive sciences. Here we discuss economic models of social preferences and how they help us to understand the psychological costs and benefits in social decisions. We then analyze recent neuroeconomic findings on social preferences with the goal of creating a coherent picture of the neural circuitry involved in social decisions. We argue that the insula and anterior cingulate cortex first determine what is socially appropriate and whether any norms have or will be violated, the amygdala generates emotional responses to these outcomes, the temporoparietal junction promotes perspective-taking, and finally the dorsolateral prefrontal cortex incorporates this information to modulate the overall utilities, and thus decisions, in the striatum and ventromedial prefrontal cortex. We conclude by discussing the implications of this research for understanding deficits in social behavior and how to potentially improve our own social behavior.
Confer with leading surgeons on the most effective way to solve complex surgical problems. 110+ pioneering surgeons share tips, pearls, and strategies Step-by-step guidance for 65+ challenging techniques 600+ illustrations demonstrate crucial details
Now with a new epilogue-- an unprecedented and unwavering history of the Supreme Court showing how its decisions have consistently favored the moneyed and powerful. Few American institutions have inflicted greater suffering on ordinary people than the Supreme Court of the United States. Since its inception, the justices of the Supreme Court have shaped a nation where children toiled in coal mines, where Americans could be forced into camps because of their race, and where a woman could be sterilized against her will by state law. The Court was the midwife of Jim Crow, the right hand of union busters, and the dead hand of the Confederacy. Nor is the modern Court a vast improvement, with its incursions on voting rights and its willingness to place elections for sale. In this powerful indictment of a venerated institution, Ian Millhiser tells the history of the Supreme Court through the eyes of the everyday people who have suffered the most from it. America ratified three constitutional amendments to provide equal rights to freed slaves, but the justices spent thirty years largely dismantling these amendments. Then they spent the next forty years rewriting them into a shield for the wealthy and the powerful. In the Warren era and the few years following it, progressive justices restored the Constitution's promises of equality, free speech, and fair justice for the accused. But, Millhiser contends, that was an historic accident. Indeed, if it weren't for several unpredictable events, Brown v. Board of Education could have gone the other way. In Injustices, Millhiser argues that the Supreme Court has seized power for itself that rightfully belongs to the people's elected representatives, and has bent the arc of American history away from justice.
Covering nearly 260 of the most common dermatologic conditions from A to Z, Treatment of Skin Disease, 6th Edition, by Drs. Mark G. Lebwohl, Warren R. Heymann, Ian Coulson, and Dedee Murrell, is your go-to resource for authoritative, evidence-based treatment strategies in your daily practice. This award-winning text provides guidance on the fast-moving dermatological therapy options for virtually any skin disease you're likely to encounter, including third-line and unusual therapies when initial options have not been successful. Summaries of each treatment strategy are accompanied by detailed discussions of treatment choices, with ratings on a consistent scale ranging from clinical studies to anecdotal reports. - Puts every possible therapeutic option at your disposal – including management strategies, first- to third-line therapies, and off-label uses – for a truly complete guide to the vast array of dermatologic treatment options. - Features 4 all-new chapters on COVID-19 dermatoses, including the associated pediatric multisystem inflammatory syndrome; DRESS syndrome; keratosis lichenoides chronica; and tinea corporis and tinea cruris. - Presents information in a consistent, tabular format, with checklists of diagnostic and investigative pearls and color-coded boxes for quick reference. - Provides more than 260 full-color clinical images of skin diseases, most of which are new to this edition. - Offers the combined knowledge and expertise of the world's leading authorities in dermatology. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
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