This book is a comprehensive reference on the methods available for the enhancement of percutaneous penetration. It examines a broad scope of chemical enhancers and various physical methods of enhancement. The range of chemicals discussed in this volume is unsurpassed anywhere in the literature. Scientists can find invaluable information in this single source on 95 percent of the enhancers being researched today! Each well-illustrated chapter is written by the world's leading authorities in the field. Introductory chapters outline the concept of penetration enhancement from first principles and provide a comprehensive classification of different types of enhancers.Chapters covering chemical enhancers are clear, concise, and easy to understand, even for novice readers in this field. The latest techniques by which drugs can be forced physically through the skin are also covered in depth. Equipment is detailed, typical drug candidates for the techniques are described, and the success to date is provided. Percutaneous Penetration Enhancers is the first book to present modern analytical techniques that have been used to assess penetration enhancement. The book also offers future perspectives for enhancers. New approaches and current limitations on knowledge and understanding of the topic are suggested. This timely source book is invaluable for clinical reference or for the design of scientific studies.
The Pyramids and the Taj Mahal are witness to the extravagant architectural tributes that, throughout human history, the great and the wealthy have paid to their dead. In this book, a well-known architectural historian provides a history of funerary architecture in western Europe from the earliest megalithic tombs of prehistory to the establishment of public cemeteries in the nineteenth century. With sensitivity and wit, Howard Colvin traces the ways in which these structures represent changing ideas about the after-life as well as changes in architectural style.
The leading reference in the field of geriatric care, Brocklehurst's Textbook of Geriatric Medicine and Gerontology, 8th Edition, provides a contemporary, global perspective on topics of importance to today's gerontologists, internal medicine physicians, and family doctors. An increased focus on frailty, along with coverage of key issues in gerontology, disease-specific geriatrics, and complex syndromes specific to the elderly, makes this 8th Edition the reference you'll turn to in order to meet the unique challenges posed by this growing patient population. - Consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more make reference quick and easy. - More than 250 figures, including algorithms, photographs, and tables, complement the text and help you find what you need on a given condition. - Clinical relevance of the latest scientific findings helps you easily apply the material to everyday practice. - A new chapter on frailty, plus an emphasis on frailty throughout the book, addresses the complex medical and social issues that affect care, and the specific knowledge and skills essential for meeting your patients' complex needs. - New content brings you up to date with information on gerontechnology, emergency and pre-hospital care, HIV and aging, intensive treatment of older adults, telemedicine, the built environment, and transcultural geriatrics. - New editor Professor John Young brings a fresh perspective and unique expertise to this edition.
Here is the story of a man with a vision for new life in urban churches. In this book, Edington shows how to use innovation to lead a congregation to numerical, financial and spiritual success. He shows pastors in the city environment proven methods for keeping their churches alive and well despite the particular obstacles facing them in the urban landscape.
This book provides a thorough introduction to what is known about why people visit museums, what they do there, and that they learn. It offers recommendations and guidelines to help museum staff understand their clientele and their interactions with them.
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