The authors show how systematic screenings of behavior--used in conjunction with academic data--can enhance teachers' ability to teach and support all students within a response-to-intervention framework. Chapters review reliable, valid screening measures for all grade levels, discuss their strengths and weaknesses, and explain how to administer, score, and interpret them. --from publisher description
Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale clinical trials to cure severe immunodeficiency in children. However, their successes were overshadowed some time later by the occurrence of vector-related leukaemia in a number of treated children. It is in this context that lentiviral vectors have appeared, with improved efficiency and, possibly, increased biosafety. Very recently, the first clinical trials with lentivectors have been carried out with some success. This Brief firstly defines gene therapy, and places lentivectors within this fascinating therapeutic strategy. Then follows a comprehensive description of the development of retroviral and lentiviral vectors and how to specifically target distinct cell types and tissues. The authors also discuss the application of lentivector gene therapy for the treatment of cancer and autoimmune diseases, ending with the application of lentivectors in human gene therapy clinical trials.
A free open access ebook is available upon publication. Learn more at www.luminosoa.org. In this vitally important book, medical anthropologist Holly Wardlow takes readers through a ten-year history of the AIDS epidemic in Tari, Papua New Guinea, focusing on the political and economic factors that make women vulnerable to HIV and on their experiences with antiretroviral therapy. Alive with the women’s stories about being trafficked to gold mines, resisting polygynous marriages, and struggling to be perceived as morally upright, Fencing in AIDS demonstrates that being female shapes every aspect of the AIDS epidemic. Offering crucial insights into the anthropologies of mining, ethics, and gender, this is essential reading for scholars and professionals addressing the global AIDS crisis today.
(FAQ). TV Finales FAQ is the first book devoted exclusively to television's most memorable series finales. From Mary Richards' heartfelt goodbye to the WJM-TV newsroom in the classic finale of The Mary Tyler Moore Show to the puzzling conclusion of the enigmatic adventure series, Lost , to the tumultuous final hours in the life of Breaking Bad 's Walter White, TV Finales FAQ takes an up close, insightful, and entertaining look at the most memorable final episodes of television's most popular prime time, daytime, and late night series. Crafting the final episode to a long-running television series can be challenging for producers and writers who want to remain faithful to the show's characters and history, yet, at the same time, satisfy the high expectations of its loyal fan base. TV Finales FAQ offers television viewers the inside story on the creation, broadcast, and aftermath of the most famous (and infamous) final episodes of over 50 television series from the 1960s through the present day. The books features such shows as Dexter , Roseanne , Will & Grace , X-Files , The Sopranos , and some classic talk and late-night programs such as The Oprah Winfrey Show and The Tonight Show Starring Johnny Carson , and many others.
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