During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects oflife at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for replicating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macro molecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of informa tion with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective what is known about the field today - and a description of the frontiers of research where our knowledge is increasing steadily.
Tucked between the larger commonwealths of Pennsylvania and Virginia and overshadowed by the political maneuverings of its neighbor, Washington, D.C., Maryland has often been overlooked and neglected in studies of state governmental systems. With the publication of Maryland Politics and Government, the challenging demographic diversity, geographic variety, and dynamic Democratic pragmatism of Maryland finally get their due. Two longtime political analysts, Herbert C. Smith and John T. Willis, conduct a sustained inquiry into topics including the Maryland identity, political history, and interest groups; the three branches of state government; and policy areas such as taxation, spending, transportation, and the environment. Smith and Willis also establish a “Two Marylands” model that explains the dominance of the Maryland Democratic Party, established in the post–Civil War era, that persists to this day even in a time of political polarization. Unique in its scope, detail, and coverage, Maryland Politics and Government sets the standard for understanding the politics of the Free State (or, alternately, the Old Line State) for years to come.
This volume, edited for the last time by H.E. Spiegel, continues the objective of expanding the intellectual horizon of clinical chemistry. The fields of analytical, anatomical, sub-cellular and molecular sciences are all represented in this volume.* Detailed reviews by practicing scientists* Covers a broad range of clinical chemistry on a theoretical and practical basis* Includes easy to read chapters combining science and perspectives in a changing scientific landscape
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