Proteomics - the analysis of the whole set of proteins and their functions in a cell - is based on the revolutionary developments which have been achieved in protein analysis during the last years. The number of finished genome projects is growing and in parallel there is a dramatically increasing need to identify the products of revealed genes. Acting on a micro level modern protein chemistry increases our understanding of biological events by elucidating the relevant structure-function relationships. The second edition of the successful title Microcharacterization of Proteins presents a current overview of modern protein analysis: From sample preparation to sequence analysis, mass spectrometry and bioinformatics it informs about the tools needed in protein research. This makes the book indispensable for everyone involved in proteomics!
This book presents a cross-disciplinary and methodologically innovative study, combining historical macro-sociology and a sociology of emotions with historical anthropology and cultural studies. Drawing on the concepts and theories of Norbert Elias on the Civilizing Process, it sets out to pin down and compare qualities that are simultaneously instantly recognisable and highly elusive, that is a kind of typical 'Englishness' and of 'Austrianness' that developed contemporaneously in the period up to the First World War. The authors chart the development of political authority structures in their varied historical manifestations, as well as their affective sedimentation as collective habitus ( national character ), comparing England and Austria from 1700 to 1900 as a case study. Their argument is based on an analysis of literary sources, mainly novels and plays, applying a sociology of literature approach. Axtmann and Kuzmics argue that the very different national characters formed in England and Austria during this time are related to differences in the affective experience of power and powerlessness, in short, of authority. They show that the formation of national character is determined partly by the different mixture of authoritative external constraints and milder self-restraint, and partly by the affective experience of human beings in uneven power balances. Specifically, they show how the formation of the bureaucratic state with strong patrimonial features in Austria, and of a self-organizing civil society with strong bourgeois-liberal features in England resulted both in different institutional structures of authority, and in different modes of the affective experience of this authority. Employing empirical detail of individual cases and texts to analyse and illuminate broad processes, the authors reach a clearer and deeper understanding of seemingly intangible and irrational aspects of national identity.
In the first work to comprehensively cover this all-important topic, the recognized expert Helmut Vorbrüggen provides both organic and bioorganic chemists with much new and valuable information for preparative synthesis. Although every organic chemist may be familiar with different aspects of silylation for the protection of functional groups, this book covers the concept of protection while simultaneously silylating-activating various functional groups, such as amides and ureas. This novel methodology opens thus numerous synthetic pathways while effecting the elimination of water in it volatile persilylated form under rather mild reaction conditions, which are often advantageous compared to conventional methods. The compact form and clear structure of this monograph make this a long-awaited ready reference. From the contents: Introduction * Techniques of Preparative Silylations-Desilylations * Preparation and Properties of Siliconoxy-Leaving Groups * Reactions of Free and Derivatized Carboxylic Acids and Carbon Dioxide * Reactions of Aldehydes and Ketones * Reactions of Alcohols, Ethers and Epoxides * Reaction of N-O Systems * Reactions of S-O and Se-O Systems * Cyclizations and Ring Enlargements * Base and Acid-Catalyzed as well as Thermal Eliminations of Trimethylsilanol. Peterson Reactions * Formation of Carbon-Phosphorous Double- and Triple Bonds * Reductions and Oxidations * Dehydration-Activation as well as Silylation of Inorganic and Organic Salts and Metalorganic Compounds * Formation of Polymers
Biophysics is a new way of looking at living matter. It uses quantitative experimental, theoretical, and computational methods, thereby opening a new window for studying and understanding life processes. This textbook provides a brief introduction to the basics of the field, followed by in-depth discussions of more advanced biophysics subjects, going all the way to state-of-the-art experiments and their theoretical interpretations. The second edition presents some of the newest developments in the field (e.g., biomolecular condensates, loop extrusion), a new chapter on computational methods, and many computer exercises specially designed for this textbook.
The monophylum Oxytrichidae (Ciliophora, Hypotrichia) contains freshwater-, marine-, and soil-dwelling species. Some taxa are extremely widespread in freshwater (e.g. Oxytricha, Stylonychia) or in terrestrial habitats (e.g. Gonostomum). Oxytricha and Stylonychia have been used for many molecular, ultrastructural, and genetic investigations. This is the first book since Ehrenberg's (1838) monumental work to summarize the morphological, morphogenetic, faunistic, and ecological data from the past 220 years, scattered in more than 2500 references from all over the world. One central dichotomous key leads directly to 32 genera comprising about 169 species, which are illustrated by more than 2400 figures, including original ones. Taxonomists, ecologists, limnologists, soil biologists, and cell biologists will find a list of synonyms, a discussion of nomenclatural and taxonomic problems, and a detailed morphological and ecological description, including almost all published faunistic records. This enables both the specialist and the practitioner to determine species without referring back to the original literature. The book offers the interested scientist a thorough and up-to-date revision of the oxytrichids.
Dermatology" covers all the classical and related fields of dermatology, providing a wealth of infor- mation on clinical features, pathophysiology, and differen- tial diagnosis. Approximately 850 excellent color figures help the reader become acquainted with the immense variety of dermatological diseases. Each chapter contains detailed proposals for comprehensive therapy. The book is a must for every doctor confronted with dermatological problems.
Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression.*Coenzyme Q: Detection and Quinone Reductases*Plasma Membrane Quinone Reductases*Quinones, Cellular Signaling, and Modulation of Gene Expression
This volume, based on presentations from the symposium on the health effects of alcohol held in Titisee, Germany, examines the physical and psychological consequences of alcohol use and abuse, and considers environmental and ethnic factors that lead to addiction and dependence. Discusses epidemiological studies that show the influence of light to moderate intake of alcoholic beverages on coronary heart disease. Featuring contributions from nearly 60 internationally recognized and respected authors, and over 2900 references for further investigation of the subject, Alcohol in Health and Disease analyzes biochemical, pharmacogenetic, and pathologic disturbances that follow acute and chronic ingestion of alcohol; describes complications that arise from social, biological, and environmental factors; examines alcohol metabolic genes and their role in alcohol sensitivity, drinking habits, and dependence; spotlights hepatic and nutritional disorders associated with alcoholism; considers the relationship of alcohol to cancer; debates the French paradox and more. Covering a multitude of disciplines, including molecular biochemistry, genetics, epidemiology, pathophysiology, neurobiology, and cardiology, Alcohol in Health and Disease is a critical reference for addiction psychiatrists, neuropsychopharmacologists, psychologists, geneticists, toxicologists, biochemists, environmental and public health scientists, health policy makers, social workers, counselors, and graduate and medical school students in these disciplines.
This volume presents the proceedings of a Coimbra Group conference on networking across borders and frontiers in European culture and society that took place at the University of Graz in September 2007. Organised by the Task Force on Culture, Arts and Humanities it brought together researches from ten different European countries and an array of disciplines across the Humanities and Social Sciences spectrum, from Cultural Anthropology, European Ethnology, History, Literary Studies and Fine Arts to Peace Studies, Sociology and Political Sciences. It explores the capacity of the frontier-network binary for describing and analysing historical, cultural and political processes in the formation of European cultures and societies past and present, and across national and disciplinary boundaries.
An individual's life story can provide insights into the character of a particular nation, the events of a specific time period, and the hopes and challenges faced by human beings as they strive to live a life that is consistent with the ideals that they espouse. This memoir of Helmut Hartmann's first seventy years of life serves such a multifaceted purpose. Hartmann was born shortly before Adolf Hitler and the National Socialists gained power in Germany. His memories of his childhood include impressions of a society in turmoil and of the persistent suffering experienced by segments of German society, particularly the Jewish community. In his adult years, Hartmann served as a pastor of the Evangelical Church in the German Democratic Republic. His account of his diverse pastoral ministry; his travels, both within and outside the Soviet Bloc countries; his engagement with the Communist political leaders; and his diligent quest for justice highlights the religious, political, economic, and social challenges faced by East German citizens while they were ruled by a political regime that was ardently anti-religious and eagerly exercised its dictatorial authority. Hartmann's memoir invites readers to consider what it means to be a follower of Christ and how their faith might inform their responses to the societal, political, and economic challenges of their particular time and place.
Since the discovery of ferrocene and the sandwich-type complexes, the development of organometallic chemistry took its course like an avalanche and became one of the scientific success stories of the second half of the twentieth century. Based on this development, the traditional boundaries between inorganic and organic chemistry gradually disappeared and a rebirth of the nowadays highly important field of homogeneous catalysis occurred. It is fair to say that despite the fact that the key discovery, which sparked it all off, was made more than 50 years ago, organometallic chemistry remains a young and lively discipline.
Bringing together a truly global range of scholars, this volume explores heritage, memory, and identity through a diverse set of subjects, including heritage sites, practices of memorialization, museums, sites of contestation, and human rights.
The aim of this monograph is to outline the physics of image formation, electron–specimen interactions, and image interpretation in transmission el- tron microscopy. Since the last edition, transmission electron microscopy has undergone a rapid evolution. The introduction of monochromators and - proved energy ?lters has allowed electron energy-loss spectra with an energy resolution down to about 0.1 eV to be obtained, and aberration correctors are now available that push the point-to-point resolution limit down below 0.1 nm. After the untimely death of Ludwig Reimer, Dr. Koelsch from Springer- Verlag asked me if I would be willing to prepare a new edition of the book. As it had served me as a reference for more than 20 years, I agreed without hesitation. Distinct from more specialized books on speci?c topics and from books intended for classroom teaching, the Reimer book starts with the basic principles and gives a broad survey of the state-of-the-art methods, comp- mented by a list of references to allow the reader to ?nd further details in the literature. The main objective of this revised edition was therefore to include the new developments but leave the character of the book intact. The presentation of the material follows the format of the previous e- tion as outlined in the preface to that volume, which immediately follows. A few derivations have been modi?ed to correspond more closely to modern textbooks on quantum mechanics, scattering theory, or solid state physics.
A complete guide to colonoscopy featuring more than 1,000 superb illustrations! In recent decades, colonoscopy has developed into one of the most essential techniques for early screening, detection, and diagnosis of colorectal cancer, inflammatory bowel disease, and other disorders. And rapid advances in interventional endoscopy offer doctors and patients an ever-increasing array of treatment possibilities. For newcomers to the technique and advanced practitioners alike, this lavishly illustrated atlas is a state-of-the-art guide to total colonoscopy. Atlas of Colonoscopy is... Accessible: Expert authors present all of the necessary instruments and examination techniques, as well as guidelines on preparation, related medications, complications, and more. Tips and tricks for instrument insertion and guidance Illustrated, thorough descriptions of normal findings in all colon segments A logical structure and easy-to-use-layout Practical: Detailed descriptions and multiple illustrations of numerous pathological findings Endoscopic criteria and differential diagnoses for all major diseases Useful guide to examination procedures depending on clinical findings Detailed: Coverage of the complete spectrum of interventional colonoscopy, including polypectomy, mucosectomy, tumor treatment, removing foreign objects, treating fistulas, and suture insufficiency Indications and success rates of various treatments, including thermocoagulation, injection, and mechanical treatments Compiled by a team of experts with decades of combined experience in the field, the Atlas of Colonoscopy is an essential resource for anyone working in an endoscopy unit.
First authoritative, comprehensive study of photography from a purely aesthetic point of view, spanning its history from daguerreotypes to modern photo-reportage. 240 superb photographs. First inexpensive paperback edition.
The idea for the present volume stems from the In many cases we had to decide ourselves what long time friendship between the series editor and changes had to be made in the manuscript. This the volume editor. The field work was carried out was done, however, with the prior consent of during several years of the last two decades by Professor Pandeya. We hope that we did not Professor Pandeya and his team of workers: overlook any items which should have been S. C. Sharma, H. K. Jain, K. C. Paliwal, V. M. changed - if we did, it is our responsibility. In Bhanot, S. J. Pathak, R. Sharma, S. C. Bhatt, P. K. order to demonstrate our responsibility I have Mathur, Y. N. Rao and G. V. Saratbabu. The wide signed as co-editor of this volume. scope of the undertaking required expeditions and The series editor accepted this unusual task individual field studies for which reports were because the topic is of great significance for dry available. subtropical regions of the world. It was the task of Professor Pandey a to sift all The Cenchrus grasslands are of great importance this information and put it together in a form in the dry areas of South East Asia. The value of understandable for an international audience. the ecological grassland study for range manage The manuscript was delivered to the series edi ment is therefore obvious.
The Cylinder investigates the surprising proliferation of cylindrical objects in the nineteenth century, such as steam engines, phonographs, panoramas, rotary printing presses, silos, safety locks, and many more. Examining this phenomenon through the lens of kinematics, the science of forcing motion, Helmut Müller-Sievers provides a new view of the history of mechanics and of the culture of the industrial revolution, including its literature, that focuses on the metaphysics and aesthetics of motion. Müller-Sievers explores how nineteenth-century prose falls in with the specific rhythm of cylindrical machinery, re-imagines the curvature of cylindrical spaces, and conjoins narrative progress and reflection in a single stylistic motion. Illuminating the intersection of engineering, culture, and literature, he argues for a concept of culture that includes an epoch’s relation to the motion of its machines.
Anglo-Saxon Manuscripts is the first publication to list every surviving manuscript or manuscript fragment written in Anglo-Saxon England between the seventh and the eleventh centuries or imported into the country during that time. Each of the 1,291 entries in Helmut Gneuss and Michael Lapidge's Bibliographical Handlist not only details the origins, contents, current location, script, and decoration of the manuscript, but also provides bibliographic entries that list facsimiles, editions, linguistic analyses, and general studies relevant to that manuscript. A general bibliography, designed to provide full details of author-date references cited in the individual entries, includes more than 4,000 items. Compiled by two of the field's greatest living scholars, the Gneuss-Lapidge Bibliographical Handlist stands to become the most important single-volume research tool to appear in the field since Greenfield and Robinson's Bibliography of Publications on Old English Literature. Their achievement in the present book will endure for many decades and serve as a catalyst for new research across several disciplines.
This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1964.
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