Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of α-crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina. A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.
Ever wanted to start a fitness program but not invest a fortune in a gym membership, equipment, or a set of DVDs? This book has it all! A complete routine that can be done at home with no equipment necessary! A program designed to grow with you and challenge you, whatever your current level of fitness is. Each exercise is thoroughly explained and includes graphics to help you understand. Getting fit isn't easy, but this book will help you get started. Along with a thoroughly explained exercise routine, some tips on proper nutrition are also included. This is a great starter book for those new to exercise and will provide a great challenge to experienced athletes. Fitness truly is for everyone, including you! "I believe this program can help anyone find his or her inner champion. The simplicity and ability to perform all these exercises in the comfort of your own home gives you the upperhand. The knowledge and programming in this book is top quality. I support this program along with AdvoCare products." - Rustie Aguilar (AdvoCare Advisor) ISSA Certified Elite Trainer Level 1 "The No Excuses workout is one of the best full body workouts I have ever done! Whenever I have any fitness questions, Jeff is always there to answer, help, and support me. Thanks for another awesome book!" - Susan Mohler Sales Specialist for Eileen Fisher
Bus Stop for Eternity is a celebration of life lived from the inside out. This series of poems and short stories will provide spiritual insight and encourage deep contemplation. Weaving humor and serendipity throughout profound topics, this book will lead readers to their sacred inner space—the place where thoughts, ideas…even dreams are created and begin to manifest into reality.
From time to time, we all may tell a little liea fib. But what if everyone in your family did? Thats the problem in author Brady Hauswirths Fib Fibinowski: The Fibinowski Fibbers. The Fibinowski parents are fibbers, and they are teaching their children to fib as well. But then one of the Fibinowskis decides not to be a fibber anymore. Learn what happens to the entire family when one person makes a change and vows never to again lie. Parents influence their children for the bad and for the good. Fib Fibinowski: The Fibinowski Fibbers shows that sometimes, children influence their parents. It is a fun way to talk about lying while stressing the importance of truth.
First published in 2006. Purdah, which can be formal law or informal custom, involves keeping women segregated from society, restricting their independence and regulating their dress. This classic work, published in 1032 was the first accurate description of the institution of Purdah, its effects on the women of India and their rising revolt against it. Written by a woman who herself lived the life pictured in the books, this was a seminal book for the women's rights movement and general and Indian's women's movement in particular.
This book develops a conceptual framework for the relationship between organisation and output, and applies it to the analysis of German and British export support services. These findings help to explain why one organisation may be different from another, but equally effective and efficient, and why no panacea for effective and efficient organisation has been found. They also suggest angles from which existing organisations and blueprints of ‘better’ organisations can be examined.
Avoid expensive lawsuits and still fulfill your legal obligations by consulting the PARTICIPANT DIRECTED INVESTMENT ANSWER BOOK. Leading experts in benefits and investment advice explain how you can protect yourself and still provide employees with the information they need to make decisions on individual contribution plans. Clear guidelines are laid out for designing a plan, administering it, and evaluating and managing costs. Complex responsibilities and regulations are simplified and thoroughly explained to ensure that you understand and comply with the latest procedures. Some of the topics covered in the Second Edition include: Fiduciary liabilities and the protections provided by ERISA Customizing the best plan to incorporate appropriate options and features Basic principles of investing and differeing types of investment vehicles Department of Labor guidelines for participant investment education programs Tax advantages or disadvantages of qualified plans and more. This comprehensive book also includes a straightforward Retirement Planning Worksheet with calculation tables to show participants how to estimate retirement income needs. Nowhere else can you find such authoritative answers to all of your questions.
Avoid expensive lawsuits and still fulfill your legal obligations by consulting the Participant Directed Investment Answer Book. Leading experts in benefits and investment advice explain how you can protect yourself and still provide employees with the information they need to make decisions on individual contribution plans. Clear guidelines are laid out for designing a plan, administering it, and evaluating and managing costs. Complex responsibilities and regulations are simplified and thoroughly explained to ensure that you understand and comply with the latest procedures. Some of the topics covered in the Answer Book include: Fiduciary liabilities and the protections provided by ERISA Various types of plans and the advantages and disadvantages of each Customizing the best plan to incorporate appropriate options and features Basic principles of investing and different types of investment vehicles Important administrative issues such as plan communication Department of Labor guidelines for participant investment education programs Tax advantages or disadvantages of qualified plans Trends in participant directed investment plans and more! This comprehensive book also includes a straightforward Retirement Planning Worksheet with calculation tables to show you how to estimate retirement income needs. Nowhere else can you find such authoritative answers to all of your questions.
This book constitutes the proceedings of the 12th International Conference on Web Information Systems Engineering, WISE 2011, held in Sydney, Australia, in October 2011. The 17 revised full papers and 11 revised short papers presented together with 7 demo papers were carefully reviewed and selected from 96 submissions. The papers contained in these proceedings address challenging issues in software services, Web application engineering and modelling, Web search, social networks, Web semantics, and information retrieval and extraction.
Hatha Yoga for Teachers and Practitioners is a must-read if you want to derive maximum benefits from your yoga practice and master the art of comprehensive sequencing. You will be presented with powerful tools to classify yoga poses and instantly create customized sequences for different levels, themes, and goals. Starting from the traditional approach to yoga, you will discover how yoga poses affect the internal body and how systematic yoga sequencing can increase your holistic health and well being. You will also understand the medically-proven benefits of yoga and you will learn the ancient principles of sequencing asanas according to their corresponding chakras (energy centres). Esteemed yoga teachers and trainers of more than 2000 yoga teachers, Ram Jain and Kalyani Hauswirth-Jain describe how to create safe, fulfilling, and holistic Hatha Yoga practices. Ram and Kalyani provide you with practical descriptions of over 200 asanas, with their respective instructions, alignment cues, contraindications, and modifications - which will bring your yoga classes and practice to a whole new level. Ram Jain Ram is Founding Director of the Arhanta Yoga Ashrams (India and The Netherlands). Within the last 10 years, the Arhanta Yoga Ashrams have become renowned internationally for their professional yoga teacher training courses, and have up to present trained over 1,500 yoga teachers from all over the world. Born in New Delhi, India, in a traditional and spiritual family, his yoga and Vedic philosophy education started at the age of eight years as a part of his primary school education. He has in-depth knowledge of classical Hatha Yoga and is also well versed in ancient Indian scriptures. During his 19 years of teaching career, he has worked with various anatomy and physiology experts and has developed unique teaching, adjustment, and modification techniques. Presently, he is the lead teacher for various teacher training programs, ranging from Hatha Yoga, Yin Yoga, Vinyasa Yoga, to Meditation and Yoga Nidra. He teaches for several months a year in India and the rest of the year in the Netherlands, where he also lives with his wife and two children. Kalyani Hauswirth-Jain Kalyani was born and raised in Switzerland. Since early adolescence she has been fascinated by art, bodywork, the body-mind connection, and alternative therapies. Following her strong inclination for art and physical expression she emigrated to the Netherlands at the age of 19 to study Modern Dance. Soon after she was exposed to the teachings and practice of yoga and was immediately mesmerized. The mother of two children now, she has been teaching yoga for 10 years, training yoga teachers for more than six years at the Arhanta Yoga Ashrams in India and the Netherlands. Starting off with physical challenges, she transformed her body, mastering many advanced asanas with her regular practice and discipline. By following a diligent self-practice, working with many different teachers, styles, and techniques, she gained a profound understanding of physiology and movement techniques. This, in combination with her extensive teaching experience, gave her an understanding of the importance of structure and sequencing for a holistic yoga asana practice.
Have you ever wanted to start weight training, but didn't know where to start? Have you ever gone to the gym, only to be frustrated because you don't know what you should be doing?
Things My Mother Told Me: Reflections on Parenthood is a book written from the perspective of one who longs to conceive and nurture a child. Its warm anecdotes describe emotional and spiritual milestones in the life of a child, via memorable examples of thoughtful parenting.
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