Is it possible that the Lord will visit the UK and Southern-Ireland with another heaven-sent Revival? The author believes that this is what the Lord has promised as he prayer-walked the length and breadth of Wales, Northern and Southern- Ireland, Scotland and England, and experienced the Lord guiding and providing each step of the way. The Lord particularly blessed him through the love and kindnesses of the numerous folk he met along the way. Read how from slow stuttering steps on a trial run, when he barely managed to prayer-walk 2 miles, how he was able to complete in total, nearly 2,000 miles. On one particular day (and into the early hours of the next one) he was enabled to prayer-walk 45 miles.
Social work has laboured too long under a 'deficit' model that focuses on failings and problems of practice. Emphasising best practice, strengths and collaborative partnership this ambitious book seeks to redress the balance. Undergraduate and post-qualifying social work students alike will find it a useful resource.
Well-established and highly regarded, Street on Torts provides a detailed yet clear overview of tort law, with strong analysis of case law and contextualisation of individual torts. The highly praised broad coverage and logical structure are maintained, ensuring the book remains a classic 50 years after publication of the first edition.
This two volume set contains comprehensive coverage of management of disorders of the adult hip. It includes all arthroscopic and open procedures as well as extensive coverage of equipment and prostheses.
This volume is an account of scientific discovery related to the hepatitis E virus (HEV). HEV was first identified in Afghanistan in 1982 by a remarkably courageous act of self-experimentation by a Russian scientist. Following this, it was found that, in some developing countries in Asia and Africa, HEV was the cause of enormous outbreaks of hepatitis spread by infected drinking water, with a 25% death rate in pregnant women. For many years, HEV was thought not to be an issue in high-income countries and was only seen in travellers returning from high risk areas: it was considered a “back-packers’” disease. We now know that this was hopelessly wrong as HEV is very common in developed countries, with currently over 2 million infections per year in Europe. Here, HEV is found in pigs and spread mainly via consumption of contaminated pork meat. There has been a major increase in cases of HEV in many developed countries, including patients who have suffered liver failure, some of whom have died. We now know that HEV can also cause severe damage to the nervous system. This book describes an English doctor’s contribution to the discovery of the impact of HEV in humans. Recent cases in the UK appear to have originated from pigs in Continental Europe and HEV was, as a consequence, dubbed by the international press as the ‘Brexit Virus’; perhaps an early leaving present from our friends in the EU. Accessible to lay readers, the text includes case histories and stories from a health service increasingly under pressure and given context by examples of medical discoveries from the past. The role of the meat production industry, including questionable on-going high-risk virological practices, is put under the spotlight, leading to inevitable comparisons with the BSE crisis of the 1980s. HEV continues to exact a heavy toll in some low-income countries, most notably with multiple large outbreaks in African refugee camps. Despite the best efforts of organisations such as Médecins Sans Frontières, each year, pregnant women continue to die by the score. This is particularly poignant as these deaths may be avoidable, as there is a safe and effective vaccine. However, the HEV vaccine is only licensed for use in China, and, so far, efforts to introduce it to Africa have hit a brick wall of politics and red tape.
Epilepsy affects 40 million people worldwide. With appropriate treatment most can become seizure free. For a minority of patients who also suffer from psychiatric comorbidity, however, diagnosis and management may be complicated by uncontrolled seizures, associated stigma or by the treatment of the epilepsy itself. Written by the world's foremost authorities on the neuropsychiatric manifestations of epilepsy, Psychiatric Comorbidity in Epilepsy is a comprehensive clinical, research, and treatment text for health care professionals -- including psychiatrists, neurologists, and neuropsychologists -- who treat patients with epilepsy and comorbid psychiatric problems. Based on a thorough knowledge of contemporary neuroscience, this book addresses the critical psychosocial and psychiatric issues that can affect patient care, including depression, psychosis, nonepileptic seizure-like events, antiepileptic drug toxicity, and family issues. This book also examines the possible links between the neurobiology of neuropsychiatric illness and the neurobiology of seizures, providing insight into brain behavior relations.
Now fully revised and updated the classic book on effective R&D management "This thoughtful and detailed work outlines what is required in order to achieve the desired end results in a networked world where teamwork and collaboration are increasingly important to globally dispersed workforces." JOHN CHAMBERS, Chairman and CEO, Cisco Praise for the Second Edition "This is a superbly written book and could make an excellent reference and text for related university courses." E. LILE MURPHREE, JR., PHD, former Chairman, Department of Engineering Management, The George Washington University "Provides a superb exposition of the role that social and psychological phenomena play in today's organizations." FRED E. FIEDLER, Professor of Psychology Emeritus, University of Washington, Seattle As the economy shifts from producing goods to producing information, the role of researchers in shaping the future has become immense. By taking advantage of modern technology, the highly trained and predominantly autonomous researchers from around the globe collect and share information better than ever yet, there is still a lack of an effective centralized structure for an R&D organization manager to integrate the efforts from many disparate individuals into a unified plan. Managing Research, Development, and Innovation, Third Edition covers the management skills and leadership theories essential to generating products and excelling in today's global economy. Topics of interest include how to design jobs, organize hierarchies, resolve conflicts, motivate employees, and create an innovative work environment. Discover how superior management skills can increase funding, generate profit, and improve the effectiveness of technologically based organizations. This new revised edition: Covers all aspects of the research and development process with focus on the human management function Includes two new chapters covering the innovation process critical to research and development of new products and services Outlines the challenging issues related to diversity in science and technology organizations and provides insights as to how diversity can be used to enhance creativity Managing Research, Development, and Innovation, Third Edition is the most complete, insightful book of its kind. Useful for professionals and graduate students alike, the text demonstrates in clear, straightforward prose how good management skills will shape the future.
The book is designed to be a textbook for university students (MSc-PhD level) and a reference for researchers and practitioners. It is an introduction to dynamic modelling of forest growth based on ecological theory but aiming for practical applications for forest management under environmental change. It is largely based on the work and research findings of the authors, but it also covers a wide range of literature relevant to process-based forest modelling in general. The models presented in the book also serve as tools for research and can be elaborated further as new research findings emerge. The material in the book is arranged such that the student starts from basic concepts and formulations, then moves towards more advanced theories and methods, finally learning about parameter estimation, model testing, and practical application. Exercises with solutions and hands-on R-code are provided to help the student digest the concepts and become proficient with the methods. The book should be useful for both forest ecologists who want to become modellers, and for applied mathematicians who want to learn about forest ecology. The basic concepts and theory are formulated in the first four chapters, including a review of traditional descriptive forest models, basic concepts of carbon balance modelling applied to trees, and theories and models of tree and forest structure. Chapter 5 provides a synthesis in the form of a core model which is further elaborated and applied in the subsequent chapters. The more advanced theories and methods in Chapters 6 and 7 comprise aspects of competition through tree interactions, and eco-evolutionary modelling, including optimisation and game theory, a topical and fast developing area of ecological modelling under climate change. Chapters 8 and 9 are devoted to parameter estimation and model calibration, showing how empirical and process-based methods and related data sources can be bridged to provide reliable predictions. Chapter 10 demonstrates some practical applications and possible future development paths of the approach. The approach in this book is unique in that the models presented are based on ecological theory and research findings, yet sufficiently simple in structure to lend themselves readily to practical application, such as regional estimates of harvest potential, or satellite-based monitoring of growth. The applicability is also related to the objective of bridging empirical and process-based approaches through data assimilation methods that combine research-based ecological measurements with standard forestry data. Importantly, the ecological basis means that it is possible to build on the existing models to advance the approach as new research findings become available.
Unusual place names evoke a sense of mystery and wonder. How did a place come to be called the "Wolf Pen" or the "Shot Factory"? Where in the world were the "Indian Old Fields" and "Brandenburg's Mill"? Researching these names often reveals fascinating stories about local history, families, events, and politics. Clark County, Kentucky is blessed with many such interesting places. The articles in this book are collected from a column in the Winchester Sun called "Where in the World? " Each article describes an historic place or person in Clark County, some well known, some not so well known. The articles were written for the Bluegrass Heritage Museum in hopes of fostering an interest in local history and the Museum. This book is intended to do the same. This work includes 62 articles that appeared in the Sun between September 6, 2007 to June 3, 2016. A few articles were updated for this publication after additional information became available.
This title is directed primarily towards health care professionals outside of the United States. The authors combine the latest evidence-based knowledge from the fields of orthodontics, plastic and neurosurgery, as well as otolaryngeal treatments, physiotherapy and manual therapy to provide new treatment strategies for clinicians interested in craniofacial problems. This approach is based on the latest clinical reasoning models. Grounded in pain science theory and modern craniofacial growth concepts, the techniques can be integrated into any manual, neuro-orthopaedic orientated treatment model. This approach can be easily used in the daily clinic and adapted to a variety of patterns of craniofacial pain. Practical, evidence-based and comprehensive Highly illustrated Clearly described manual techniques and management strategies Clinically relevant Includes contributions from leaders in the field Covers adult and paediatric treatment
Pathogenic bacteria have unique biological properties, which enable them to invade a host and cause sickness. The molecular bases of these biological properties are the determinants of pathogenicity, and the research objectives are to recognize them, identify them chemically and relate their structure to function. Most of our present knowledge comes from studies with cultures in vitro . However, there is a rising interest in bacterial behaviour in the infected host and new methods have been developed for studying it. This book describes those methods and shows how they, and a recent surge in conventional studies, are shedding light on the activities of bacterial pathogens in vivo . It discusses bacterial and host factors that operate in vivo to cause illness, showing how phenomena recognized in vitro relate to behaviour in vivo and, if evidence of relevance is not available now, indicating how it might be obtained. Sample Chapter(s). Chapter 1.1: Introduction (144 KB). Chapter 1.2: Questions about the Determinants of Bacterial Growth in Vivo (202 KB). Chapter 1.3: Questions about the Production in Vivo of Determinants of Mucosal Colonization, Penetration, Interference with Host Defence and Damage to the Host (179 KB). Chapter 1.4: Sialylation of Gonococcal Lps by Host CMP-NANA and Effect of Lactate: A Paradigm for Investigation of Behaviour in Vivo (191 KB). Chapter 1.5: Concluding Remarks (215 KB). Contents: Introduction: Questions about the Behaviour of Bacterial Pathogens In Vivo (H Smith); DNA Topology and Adaptation of Salmonella Typhimurium to an Intracellular Environment (D G Marshall et al.); New Methods for Studying Bacterial Behaviour In Vivo: The Pathogenesis of Shigella Flexneri Infection: Lessons from In Vitro and In Vivo Studies (D J Philpott et al.); Detection and Analysis of Gene Expression During Infection by In Vivo Expression Technology (D S Merrell & A Camilli); Measurement of Bacterial Gene Expression In Vivo (I Hautefort & J C D Hinton); Identification and Analysis of Bacterial Virulence Genes In Vivo (K E Unsworth & D W Holden); Salmonella Interactions with Host Cells: In Vitro to In Viv o (B B Finlay & J H Brumell); Impact of the New Methods: In Vivo Gene Expression and the Adaptive Response: From Pathogenesis to Vaccines and Antimicrobials (D M Heithoff et al.); Challenge of Investigating Biologically Relevant Functions of Virulence Factors in Bacterial Pathogens (R Moxon & C Tang); Virulence Gene Regulation Inside and Outside (V J DiRita et al.); Evidence for Operation In Vivo of Aspects of Pathogenicity Revealed by Recent Work In Vivo: Potential Use of New Methods: Quorum Sensing and the Population-Dependent Control of Virulence (P Williams et al.); Type III Secretion: A Bacterial Device for Close Combat with Cells of Their Eukaryotic Host (G R Cornelis); Evolution of Microbial Pathogens (J Morschhnuser et al.); The Immune Responses to Bacterial Antigens Encountered In Vivo at Mucosal Surfaces (G Dougan et al.). Readership: Graduate students and researchers in microbiology.
This new edition presents an integrated approach to neurotoxicology, the study of organisms' responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects - from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs simila
Control Theory for Linear Systems deals with the mathematical theory of feedback control of linear systems. It treats a wide range of control synthesis problems for linear state space systems with inputs and outputs. The book provides a treatment of these problems using state space methods, often with a geometric flavour. Its subject matter ranges from controllability and observability, stabilization, disturbance decoupling, and tracking and regulation, to linear quadratic regulation, H2 and H-infinity control, and robust stabilization. Each chapter of the book contains a series of exercises, intended to increase the reader's understanding of the material. Often, these exercises generalize and extend the material treated in the regular text.
Rothman-Simeone The Spine helps you achieve optimal outcomes in the clinical practice of spine surgery in adults and children. Drs. Harry N. Herkowitz, Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Richard Balderston, and an internationally diverse group of authorities help you keep up with the fast-paced field and get the best results from state-of-the-art treatments and surgical techniques, such as spinal arthroplasty and the latest spinal implants and equipment. An all-new full-color design and surgical videos online at www.expertconsult.com make this classic text more invaluable than ever before. Get the best results from the full range of both surgical and non-surgical treatment approaches with guidance from the world’s most trusted authorities in orthopaedic spine surgery. Find important information quickly through pearls, pitfalls, and key points that highlight critical points. Watch experts perform key techniques in real time with videos, on DVD and online, demonstrating minimally invasive surgery: SED procedure; thorascopic techniques; lumbar discectomy; pedicle subtraction osteotomy (PSO); C1, C2 fusion; intradural tumor; cervical laminoforaminoty; and much more. Apply the newest developments in the field thanks to expert advice on minimally invasive surgery, spinal arthroplasty and the latest spinal implants and equipments. See procedures clearly through an all new full-color design with 2300 color photographs and illustrations placed in context. Access the fully searchable contents of text online at www.expertconsult.com.
Who are the Jews--a race, a people, a religious group? For over a century, non-Jews and Jews alike have tried to identify who they were--first applying the methods of physical anthropology and more recently of population genetics. In Legacy, Harry Ostrer, a medical geneticist and authority on the genetics of the Jewish people, explores not only the history of these efforts, but also the insights that genetics has provided about the histories of contemporary Jewish people. Much of the book is told through the lives of scientific pioneers. We meet Russian immigrant Maurice Fishberg; Australian Joseph Jacobs, the leading Jewish anthropologist in fin-de-siècle Europe; Chaim Sheba, a colorful Israeli geneticist and surgeon general of the Israeli Army; and Arthur Mourant, one of the foremost cataloguers of blood groups in the 20th century. As Ostrer describes their work and the work of others, he shows that to look over the genetics of Jewish groups, and to see the history of the Diaspora woven there, is truly a marvel. Here is what happened as the Jews migrated to new places and saw their numbers wax and wane, as they gained and lost adherents and thrived or were buffeted by famine, disease, wars, and persecution. Many of these groups--from North Africa, the Middle East, India--are little-known, and by telling their stories, Ostrer brings them to the forefront at a time when assimilation is literally changing the face of world Jewry. A fascinating blend of history, science, and biography, Legacy offers readers an entirely fresh perspective on the Jewish people and their history. It is as well a cutting-edge portrait of population genetics, a field which may soon take its place as a pillar of group identity alongside shared spirituality, shared social values, and a shared cultural legacy.
As knee replacement surgeries continue to grow in number worldwide, the need for an authoritative and comprehensive reference in this key area is a must for today’s orthopaedic surgeon. The Adult Knee: Knee Arthroplasty, Second Edition, brings together the knowledge and expertise of internationally recognized experts in the field in one convenient volume.
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