Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.
Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.
This book presents the latest developments in the field of forensic pathology/forensic medicine, including important advances in forensic histopathology, forensic radiology, medical malpractice, understanding of child abuse, and forensic toxicology. Various forms of trauma are addressed in individual chapters, and among the other topics covered are traffic medicine, forensic alcohol toxicology, forensic DNA analysis, forensic osteology, and international regulations. The book includes a wealth of color illustrations and numerous tables presenting key facts. The authors are leading experts in general pathology, forensic radiology, and forensic toxicology. Forensic Pathology/Forensic Medicine: Fundamentals and Perspectives will be of interest not only to specialist pathologists and those working in forensic medicine, but also to coroners, forensic physicians, students, lawyers, attorneys, and policemen.
Distillation Principles and Practice Second Edition covers all the main aspects of distillation including the thermodynamics of vapor/liquid equilibrium, the principles of distillation, the synthesis of distillation processes, the design of the equipment, and the control of process operation. Most textbooks deal in detail with the principles and laws of distilling binary mixtures. When it comes to multi-component mixtures, they refer to computer software nowadays available. One of the special features of the second edition is a clear and easy understandable presentation of the principles and laws of ternary distillation. The right understanding of ternary distillation is the link to a better understanding of multi-component distillation. Ternary distillation is the basis for a conceptual process design, for separating azeotropic mixtures by using an entrainer, and for reactive distillation, which is a rapidly developing field of distillation. Another special feature of the book is the design of distillation equipment, i.e. tray columns and packed columns. In practice, empirical know-how is preferably used in many companies, often in form of empirical equations, which are not even dimensionally correct. The objective of the proposed book is the derivation of the relevant equations for column design based on first principles. The field of column design is permanently developing with respect to the type of equipment used and the know-how of two-phase flow and interfacial mass transfer.
Planning tasks involving existing structures are currently among the most common types of contract, and almost every structure makes different demands and raises individual problems. Reflecting this state of affairs, there are a dizzying number of publications on the market, most of which are quite specialized. The Refurbishment Manual cuts through this jungle of publications. It defines terms and concepts, combines the narrowly focused perspectives of the specialists, and offers concrete approaches to this wide-ranging topic. The Refurbishment Manual closes the gap between basic constructional literature and one-sided, highly specialized technical literature. It constitutes a practical planning aid on the subject of refurbishment, providing a basic introduction to the relevant aspects of building physics, fire protection, sustainability and energy, hazardous materials, construction materials for interior and façade, historic preservation, and technical building equipment. It offers concrete tips on planning steps, methods of building analysis, and cost benchmarks, as well as clear constructional solutions with built projects as examples. A unique feature of the volume is the specially developed timeline, which allows the planner to quickly grasp, categorize, and evaluate a concrete building task and thus obtain an efficient planning overview. Planungsaufgaben im Bestand gehören derzeit zu den häufigsten Auftragsarten und nahezu jedes Bauwerk stellt andere Anforderungen und weist individuelle Probleme auf. Analog dazu gibt es auf dem Markt eine fast unüberschaubare Anzahl Publikationen in meist sehr spezialisierter Form. Der Sanierungsatlas möchte Licht in diesen Publikationsdschungel bringen: Er definiert Begrifflichkeiten, vereint die fokussierenden Betrachtungsweisen der Fachleute und vermittelt konkrete Herangehensweisen an diese weit gefächerte Thematik. Der Sanierungsatlas schließt die Lücke zwischen grundlegender Baukonstruktions- und sehr einseitig spezialisierter Fachliteratur. Das Buch stellt eine praktische Planungshilfe zum Thema Sanierung dar – und zwar in Form von relevanter Grundlagenvermittlung zu Bauphysik, Brandschutz, Nachhaltigkeits- und energetischen Aspekten, Schadstoffen, Baustoffen im Innenraum und an der Fassade, zu Aspekten der Denkmalpflege ebenso wie zur technischen Gebäudeausstattung. Er liefert konkrete Hinweise zu Planungsschritten, Methoden der Bauanalyse und Kostenkennwerten sowie anschauliche Konstruktionslösungen am Beispiel gebauter Projekte. Einzigartig ist die speziell entwickelte Zeitschiene, mit deren Hilfe eine konkrete Bauaufgabe schnell erfasst, kategorisiert und bewertet werden kann – und die dem Planer somit einen effizienten Planungsüberblick verschafft.
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