Hans Oettgen's Books

Case Studies in Allergic Disorders

By: Hans Oettgen,Raif Geha

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Case Studies in Allergic Disorders

By: Hans Oettgen,Raif Geha

Case Studies in Allergic Disorders is designed for undergraduate and graduate students in immunology, medical students, and resident physicians. It describes the basic cellular and molecular mechanisms involved in the pathogenesis of commonly occurring allergic diseases and introduces the rationale for targeted treatment of allergy. Replicating the

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Page Count

176

Publisher

Garland Science

Published Date

ISBN 10

1135012857

ISBN 13

9781135012854

MHC Ligands and Peptide Motifs

By: Hans-Georg Rammensee,Jutta Bachmann,Stefan Stevanovic

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MHC Ligands and Peptide Motifs

By: Hans-Georg Rammensee,Jutta Bachmann,Stefan Stevanovic

This book is centered on a comprehensive list of MHC peptide motifs and ligands as known to date, together with selected T cell epitopes, arranged in an easy-to-read fashion. This information is put into context by chapters on MHC gene organization, MHC structure, T cell epitope prediction, antigen processing and T cell responses. In addition, the book provides a great deal of complementary information: amino acid sequences of MHC class I alpha1 and alpha2 domains and of class II alpha1 and beta1 domains, the established or predicted composition and specificity of MHC pockets, notes on MHC nomenclature including old assignments and reference to useful internet addresses. A handy reference manual that should be helpful for all those dealing with MHC-associated peptides.

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Page Count

467

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3662221624

ISBN 13

9783662221624

Molecular Markers of Brain Tumor Cells

Implications for Diagnosis, Prognosis and Anti-Neoplastic Biological Therapy

By: Bela Bodey,Stuart E. Siegel,Hans E. Kaiser

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Molecular Markers of Brain Tumor Cells

Implications for Diagnosis, Prognosis and Anti-Neoplastic Biological Therapy

By: Bela Bodey,Stuart E. Siegel,Hans E. Kaiser

Childhood brain tumors are a diverse group of diseases characterized by the abnormal growth of tissue contained within the skull. Other than leukemia and lymphoma, brain tumors are the most common type of neoplasms that occur in children. The leading cause of death from childhood neoplasms among persons up to 19 years is brain tumors. As such, this book is a review of the most recent molecular biological research concerning brain tumors with references and comparisons to a variety of neoplastic disorders. The book then uses this information to foreshadow the direction that future anti-neoplastic therapies will take. Because of the wide spectrum of the objectives of the book, any individual involved in cancer research will greatly benefit from the work. Histopathologists, neuropathologists, clinical and research oncologists, and medical students will find this book to be an invaluable resource as a reference guide. Patients and their families will also find the book useful as it offers a comprehensive update on new, non-classical therapeutic modality options and contains a detailed description and analysis of brain tumors. Such an endeavor has yet to be undertaken by any other book and may prove to be the most comprehensive book on brain tumors thus far.

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Page Count

365

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1402028040

ISBN 13

9781402028045

Primary Immunodeficiency Diseases

A Molecular & Cellular Approach

By: Hans D. Ochs,C. I. Edward Smith,Jennifer M. Puck

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Primary Immunodeficiency Diseases

A Molecular & Cellular Approach

By: Hans D. Ochs,C. I. Edward Smith,Jennifer M. Puck

The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

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Page Count

745

Publisher

Oxford University Press

Published Date

ISBN 10

0199747962

ISBN 13

9780199747962

Immunological Aspects of Neoplasia — The Role of the Thymus

By: Bela Bodey,Stuart E. Siegel,Hans E. Kaiser

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Immunological Aspects of Neoplasia — The Role of the Thymus

By: Bela Bodey,Stuart E. Siegel,Hans E. Kaiser

Our work began where the greatest classical morphologists left off; their best work was the start of ours. As our work progressed, the rigidity of basic, previous embryological principles was broken down as scientific knowledge advanced. At the same time, the molecular, biological characterization of the cell surface receptor systems progressed enormously with the invention of NUMEROUS monoclonal antibodies. Thus, thymology became once again very important because the thymus is the first and central organ of the human immunological system. Then, the question of immuno-neuroendocrine regulation arose and has only been partially answered. Our book seeks to explore what has not been explored. The topic of thymic epithelial cells is a unique one and has never been explored in any previous book as it is explored in this one. Only a handful of great thymologists remain in the world today, especially after the great loss the medical community suffered with the passing of Dr. Good, the list includes but is not limited to: Dr. Ritter and Dr. Kendall in England, Dr. Savino in Brazil, Dr. Dardenne in France, Dr. von Gaudecker in Germany, a few others in Belgium and Holland, and it is our hope that Dr. Bodey is among them. Nonetheless, a book on the thymus has not been written in the last five years and a book such as this one has never been. This book is based on a 30-year period of research and includes references from a broad range of sources spanning the globe and all sources, even those that were the beginning of thymic research. The book, thus, is uniquely well rounded, more so that previous works.

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Page Count

212

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1402021852

ISBN 13

9781402021855

Case Studies in Allergic Disorders

By: Hans Oettgen,Raif Geha

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Case Studies in Allergic Disorders

By: Hans Oettgen,Raif Geha

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Page Count

176

Publisher

Garland Science

Published Date

ISBN 10

1135012857

ISBN 13

9781135012854

Book's by Hans Oettgen

Case Studies in Allergic Disorders

Case Studies in Allergic Disorders

MHC Ligands and Peptide Motifs

MHC Ligands and Peptide Motifs

Molecular Markers of Brain Tumor Cells

Molecular Markers of Brain Tumor Cells

Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases

Immunological Aspects of Neoplasia — The Role of the Thymus

Immunological Aspects of Neoplasia — The Role of the Thymus

Case Studies in Allergic Disorders

Case Studies in Allergic Disorders

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