Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse"--Provided by publisher.
The concept of general oxidoreductase function at the plasma level is new. Oxidoreduction at the Plasma Membrane: Relation to Growth and Transport provides the first truly comprehensive coverage of the oxidoreduction reactions in plasma membranes and the role that can now be attributed to these enzymes in controlling growth and other cell functions in plants and animals. The book describes the nature and orientation of oxidoreductases in plasma membranes; the stimulation of cell growth by oxidants reacting with transplasma membrane electron transport; changes in enzymes in tumor cells; and the basis of the growth effects and oxidoreductase stimulation of membrane transport in relation to known second messenger functions, such as cellular pH changes, calcium transport, protein phosphorylation and oxidation levels of pyridine nucleotides. The book then examines the significance of these enzymes in cell culture, tumor growth, nerve transmission, ion transport, and membrane potential. The book also presents a new approach to understanding the action of antitumor drugs and herbicides. Biochemists, biologists, oncologists, cancer researchers, physiologists, and endocrinologists will find this an indispensible reference source as they conduct studies in this exciting new area.
Written by three leading experts in the field, this textbook describes and explains all aspects of the scanning probe microscopy. Emphasis is placed on the experimental design and procedures required to optimize the performance of the various methods. Scanning Probe Microscopy covers not only the physical principles behind scanning probe microscopy but also questions of instrumental designs, basic features of the different imaging modes, and recurring artifacts. The intention is to provide a general textbook for all types of classes that address scanning probe microscopy. Third year undergraduates and beyond should be able to use it for self-study or as textbook to accompany a course on probe microscopy. Furthermore, it will be valuable as reference book in any scanning probe microscopy laboratory. Novel applications and the latest important results are also presented, and the book closes with a look at the future prospects of scanning probe microscopy, also discussing related techniques in nanoscience. Ideally suited as an introduction for graduate students, the book will also serve as a valuable reference for practising researchers developing and using scanning probe techniques.
Growth, reproduction, and geographical distribution of plants are profoundly influenced by their physiological ecology: the interaction with the surrounding physical, chemical, and biological environments. This textbook highlights mechanisms that underlie plant physiological ecology at the levels of physiology, biochemistry, biophysics, and molecular biology. At the same time, the integrative power of physiological ecology is well suited to assess the costs, benefits, and consequences of modifying plants for human needs and to evaluate the role of plants in natural and managed ecosystems. Plant Physiological Ecology, Third Edition is significantly updated, with many full color illustrations, and begins with the primary processes of carbon metabolism and transport, plant water relations, and energy balance. After considering individual leaves and whole plants, these physiological processes are then scaled up to the level of the canopy. Subsequent chapters discuss mineral nutrition and the ways in which plants cope with nutrient‐deficient or toxic soils. The book then looks at patterns of growth and allocation, life‐history traits, and interactions between plants and other organisms. Later chapters deal with traits that affect decomposition of plant material and with the consequences of plant physiological ecology at ecosystem and global levels. Plant Physiological Ecology, Third Edition features several boxed entries that extend the discussions of selected issues, a glossary, and numerous references to the primary and review literature. This significant new text is suitable for use in plant ecology courses, as well as classes ranging from plant physiology to plant molecular biology.
The fully revised and expanded fourth edition of Plant Biochemistry presents the latest science on the molecular mechanisms of plant life. The book not only covers the basic principles of plant biology, such as photosynthesis, primary and secondary metabolism, the function of phytohormones, plant genetics, and plant biotechnology, but it also addresses the various commercial applications of plant biochemistry. Plant biochemistry is not only an important field of basic science explaining the molecular function of a plant, but is also an applied science that is in the position to contribute to the solution of agricultural and pharmaceutical problems. Plants are the source of important industrial raw material such as fat and starch but they are also the basis for the production of pharmaceutics. It is expected that in the future, gene technology will lead to the extensive use of plants as a means of producing sustainable raw material for industrial purposes. As such, the techniques and use of genetic engineering to improve crop plants and to provide sustainable raw materials for the chemical and pharmaceutical industries are described in this edition. The latest research findings have been included, and areas of future research are identified. Offers the latest research findings in a concise and understandable manner Presents plant metabolism in the context of the structure and the function of plants Includes more than 300 two-color diagrams and metabolic schemes Covers the various commercial applications of plant biochemistry Provides extensive references to the recent scientific literature
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