Anti-NMDA receptor encephalitis is a newly characterized severe neuroautoimmune syndrome with a progressive, clinical course. Most often seen in females, it usually begins with a prodromal phase suggestive of an acute or subclinical upper respiratory tract infection that lasts for up to 2 weeks. This is followed by a psychotic and seizure phase in which the child may rapidly develop seizures, behavioral changes, and, less commonly in children, psychiatric symptoms, resulting in frequent misdiagnoses. The child may become mute and unresponsive but awake during the akinetic phase. Autonomic instability characterizes the hyperkinetic phase. A teratoma or, more rarely, another tumor type is found in 25% of affected adolescents beyond the first decade of life. The finding of oligoclonal protein electrophoresis (>80%) and antibodies in serum and cerebrospinal fluid directed against the NR1 subunit of the NMDA receptor confirms the diagnosis. Prognosis is improved with the appropriate use of immunosuppressant therapies. Relapses in children may be multiple and occur in 20–25% of cases. Recovery is slow and may take 3 years or longer. Even so, the child may not always regain its premorbid level of health.
Every complex human-machine system includes a computer as a critically important means of work. However, an operator's interaction with a computerized system cannot be reduced to only performing computer-based tasks. Today human-computer interaction (HCI) is not limited to trained software users. People of all ages use all different kinds of gadget
What counts as 'indigenous religion' in today ́s world? Who claims this category? What are the processes through which local entities become recognisable as 'religious' and 'indigenous'? How is all of this connected to struggles for power, rights and sovereignty? This book sheds light on the contemporary lives of indigenous religion(s), through case studies from Sápmi, Nagaland, Talamanca, Hawai`i, and Gujarat, and through a shared focus on translations, performances, mediation and sovereignty. It builds on long term case-studies and on the collaborative comparison of a long-term project, including shared fieldwork. At the center of its concerns are translations between a globalising discourse (indigenous religion in the singular) and distinct local traditions (indigenous religions in the plural). With contributions from leading scholars in the field, this book is a must read for students and researchers in indigenous religions, including those in related fields such as religious studies and social anthropology.
This book offers analytical methods for studying human work in ergonomics and psychology that are similar to ones utilized by the engineering sciences. SSAT offers not only new qualitative but also formalized and quantitative methods of analysis. This book will describe quantitative methods of task complexity and reliability assessment, application
The new edition of this popular, richly illustrated textbook and atlas features a top-notch, diverse editorial team who offer you the most current information and reliable guidance on all aspects of colposcopy. They present unparalleled coverage on the full range of topics, from basic science to clinical colposcopy to the latest information on anal disease and HPV infections in adolescents. More than 800 full-color, high-quality colpophotographs highlight all the variations seen in colposcopic practice and accompanying brief highlighted text further explains every concept. The book’s unique organization emphasizes the correlation among cytology, colposcopy, and histology to help you make the most accurate diagnosis Encompasses the expertise of first-class investigators and clinicians from a variety of disciplines, including family practice, obstetrics, pathology, and gynecology providing you with a wide range of options and perspectives. Presents side-by-side illustrations of colposcopy, cytology, and histology, making correlations easy to see and understand. Features relevant discussions and descriptive graphics to explore low and high-grade CIN and cancer and glandular lesions. Includes a list of key points at the end of each chapter that summarize essential information. Outlines all aspects of patient management, using practical, evidence-based algorithms for at-a-glance review. Features more than 50% new or replaced illustrations, providing higher-quality visual guidance. Presents best-evidence for the latest therapeutic guidelines and treatment options, so you can make better informed decisions. Provides new chapters on anal disease and HPV infections in adolescents to keep you on the cusp of the latest techniques and practices. Discusses the pitfalls and tricks of the trade of colposcopy to help you avoid complications. Includes a DVD of 9 video clips (30 minutes of footage) of procedures offering you step-by-step instructions on performing the colposcopy.
The Control of Fertility is concerned with the experimental control of fertility as a specific biological problem. It is, first of all, an attempt to summarize a collection of data hitherto either partially or not at all presented. Secondly, it attempts to indicate those avenues which hold promise for future investigation. Finally, it attempts an assessment of the implications of understandings and ignorances. The book opens with an account of the sequence of processes essential to successful sexual reproduction in mammals. This is followed by separate chapters on approaches to the inhibition of spermatogenesis, ovulation, fertilization, and free ovum development. Subsequent chapters deal with blastocyst development and implantation, biological activities of compounds affecting fertility, fertility control in men and women, the inhibition of ovulation, biological properties of ovulation inhibitors in human subjects, and effectiveness and acceptability of contraception.
Few people have more experience guiding organizational change than Greg Shea and Cassie Solomon." —Adam Grant, New York Times-bestselling author, Originals and Give and Take Featured on CNBC and in Harvard Business Review and Fast Company, Leading Successful Change is now updated for 2020 and beyond to help leaders successfully navigate the ever-increasing pace of change. When Jack Dorsey returned to Twitter as CEO in 2015, the company was in trouble. But unlike so many other social media platforms that have crumbled under tough conditions, Twitter is still alive—and thriving. How did Twitter turn itself around in one of the most turbulent and competitive industries? The change management approach of authors Gregory P. Shea and Cassie A. Solomon guided a significant area of the organization's turnaround effort. In this revised and updated edition of Leading Successful Change, Shea and Solomon share success stories from a host of companies including Twitter, Viacom, and the Conference of State Bank Supervisors, offering a tested method for leading successful change, which they have developed over a combined 50 years of helping organizations do just that. In Leading Successful Change, Shea and Solomon share: Why most change efforts failThe two key tenets for making successful changeHow to create a scene that will provide a vision of the futureThe 8 Levers of Change, a tried-and-true method for designing the work environment to support the changesHow winning companies—from IKEA to Whirlpool—are successfully implementing change Change is not optional and it is difficult—but it is also not impossible—with Leading Successful Change. "A must-use guide for anyone who is faced with leading others to a future that is better than today." —Annie McKee, author, How to Be Happy at Work. "Greg Shea and Cassie Solomon have written a novel and valuable resource for leaders of change." —Michael Useem, Professor of Management, The Wharton School, and author, The Leader's Checklist "Wonderfully concise." —Richard J. Green, Board Chairman and CEO, Firstrust Bank "The handbook for positive disruption for any leader in any industry in the 2020s." —Stephen K. Klasko, President and CEO, Thomas Jefferson University; Distinguished Fellow for the Future of Health, World Economic Forum
According to R.H. Crabtree, Metal Dihydrogen and sigma-Bond Complexes is described as `the definitive account of twentieth-century work in the area of sigma complexation'. It covers not only Kubas' discovery of dihydrogen coordination and the study of its structure and general properties but also discusses both the theoretical beliefs and experimental results of bonding and activation of dihydrogen on metal centers and the coordination and activation of C-H, B-H, X-H, and X-Y bonds, giving an overview of `one of the hottest areas in chemistry'.
Cryogenic Heat Transfer, Second Edition continues to address specific heat transfer problems that occur in the cryogenic temperature range where there are distinct differences from conventional heat transfer problems. This updated version examines the use of computer-aided design in cryogenic engineering and emphasizes commonly used computer programs to address modern cryogenic heat transfer problems. It introduces additional topics in cryogenic heat transfer that include latent heat expressions; lumped-capacity transient heat transfer; thermal stresses; Laplace transform solutions; oscillating flow heat transfer, and computer-aided heat exchanger design. It also includes new examples and homework problems throughout the book, and provides ample references for further study. New in the Second Edition: Expands on thermal properties at cryogenic temperatures to include latent heats and superfluid helium Develops the material on conduction heat transfer and divides it into four separate chapters to facilitate understanding of the separate features and computational techniques in conduction heat transfer Introduces EES (Engineering Equation Solver), a computer-aided design tool, and other computer applications such as Maple Describes special features of heat transfer at cryogenic temperatures such as analysis with variable thermal properties, heat transfer in the near-critical region, Kapitza conductance, and network analysis for free-molecular heat transfer Includes design procedures for cryogenic heat exchangers Cryogenic Heat Transfer, Second Edition discusses the unique problems surrounding conduction heat transfer at cryogenic temperatures. This second edition incorporates various computational software methods, and provides expanded and updated topics, concepts, and applications throughout. The book is designed as a textbook for students interested in thermal problems occurring at cryogenic temperatures and also serves as reference on heat transfer material for practicing cryogenic engineers.
The most comprehensive, current sickle cell disease resource—for both clinicians and researchers A Doody's Core Title for 2023! The first and only resource of its kind, Sickle Cell Disease examines this blood disorder through both clinical and research lenses. More than 80 dedicated experts in the field present their combined clinical knowledge of basic mechanisms, screening, diagnosis, management, and treatment of myriad complex complications of a single base point mutation in the human genome. Case studies with “How I Treat” authoritative insights provide overviews of common and rare complications, and Key Facts offer at-a-glance high-yield information. Filled with clinical photos, illustrations, numerous original diagrams, and with free updates available online, this unmatched resource covers: Mechanisms of sickle cell disease Historic and current research approaches The latest work in gene therapy and editing Guidelines for patient care, diagnosis, unique cases, and therapies Rare and common complications, including domestic and internationally relevant topics Psychosocial and supportive care The newest standards of therapy and future treatment options in children and adults Cardiopulmonary complications
In a landmark decision, the Federal Circuit Court of Appeals, in Signature Financial v. State Street Bank, held that business methods may be patented. This holding, together with the explosive growth of the Internet, has turned the business method patent into the "hot" new growth area of intellectual property. Business Method Patents is your guide to the unique opportunities and risks in this emerging area of IP law. Depend on it as your authoritative source for court-tested guidance on: - Mechanics of the patent application - Prior art researching - Drafting claims - Drafting the complete specification - Drawings required for business method patents - Illustrating the business system through drawings - Building a patent portfolio for attracting capital - Enforcing and licensing business method patents.
This book differs from other thermodynamics texts in its objective, which is to provide engineers with the concepts, tools, and experience needed to solve practical real-world energy problems. The presentation integrates computer tools (such as EES) with thermodynamic concepts to allow engineering students and practising engineers to solve problems they would otherwise not be able to solve. The use of examples, solved and explained in detail, and supported with property diagrams that are drawn to scale, is ubiquitous in this textbook. The examples are not trivial, drill problems, but rather complex and timely real-world problems that are of interest by themselves. As with the presentation, the solutions to these examples are complete and do not skip steps. Similarly the book includes numerous end-of-chapter problems, both typeset and online. Most of these problems are more detailed than those found in other thermodynamics textbooks. The supplements include complete solutions to all exercises, software downloads, and additional content on selected topics. These are available on the book's website www.cambridge.org/KleinandNellis.
Were Acadians better off than their rural counterparts in old regime France? Did they enjoy a Golden Age? To what degree did a distinct Acadian identity emerge before the wars and deportations of the mid-eighteenth century? In Something of a Peasant Paradise?, Gregory Kennedy compares Acadie in North America with a region of western France, the Loudunais, from which a number of the colonists originated. Kennedy considers the natural environment, the role of the state, the economy, the seigneury, and local governance in each place to show that similarities between the two societies have been greatly underestimated or ignored. The Acadian colonists and the people of the Loudunais were frontier peoples, with dispersed settlement patterns based on kin groups, who sought to make the best use of the land and to profit from trade opportunities. Both societies were hierarchical, demonstrated a high degree of political agency, and employed the same institutions of local governance to organize their affairs and negotiate state demands. Neither group was inherently more prosperous, egalitarian, or independent-minded than the other. Rather, the emergence of a distinct Acadian identity can be traced to the gradual adaptation of traditional methods, institutions, and ideas to their new environmental and political situations. A compelling comparative analysis based on archival evidence on both sides of the Atlantic, Something of a Peasant Paradise? Challenges the traditional historiography and demonstrates that Acadian society shared many of its characteristics with other French rural societies of the period.
This is a lavishly illustrated history of the Oregon-American Lumber Company, during its heyday one of the most important lumber firms in the Pacific Northwest. Operating from 1922 until its closure in 1957, the company provides an illuminating example of the history of lumbering in the region, showing in detail both the opportunities and problems encountered by firms seeking to exploit the area’s rich natural stands of Douglas fir. The story is enhanced by the inclusion of 285 illustrations, most of which are previously unpublished, that depict logging, railroading, and sawmilling activities, and 17 period-specific maps that give the reader a unique perspective on the growth of the company. The lumbering industry was pivotal to America’s settlement and development, reaching its zenith in the period covered by this book, which shows how Oregon-American’s survival depended on successfully adapting to great changes in market forces and in industry structures, to natural disasters, and to economic crises like the Great Depression. Essential to the company’s objective of supplying lumber to markets in the Midwest farm belt was its relationship with the Great Northern and Northern Pacific Railroads; accordingly, the book provides much information on the railroad networks that made timber extraction possible. The study is based on fifteen years of archival and on-the-ground research and draws heavily on the extensive collection of Oregon-American records, notably the correspondence files of Judd Greenman, the company president who conceived and executed most of the company’s operating policies. It also includes, as sidebars, engaging oral histories related by employees, which enrich the text and provide a vivid contrast between management and employee viewpoints.
Examining US-China-Russia Foreign Relations explores the changing nature and function of the US–China–Russia strategic triangle from the end of the Cold War up to the present. Gregory Hall uses neoclassical realist international relations (IR) theory to argue that, since the mid-2000s, the politics of the strategic triangle have been increasingly influenced by factors related to the Big3 countries’ respective domestic environments. Hall utilizes agency and context for each of the three great powers, expanding on previously established frameworks to include a comparative analysis of each actor’s domestic environment for foreign policy and the interplay between the domestic and external contexts. In IR terms, the book identifies and illustrates how factors including systemic, state and societal, individuals, and small groups influence the foreign relations of the Big3. Hall concludes by exploring the future prospects for great power relations and for global affairs. Incorporating both theoretical and empirical data to offer a fresh and timely look at the myriad challenges facing the three powers, this book provides an excellent companion to students of foreign policy, international security, and post-Cold War international politics.
Experimental Methods and Instrumentation for Chemical Engineers, Second Edition, touches many aspects of engineering practice, research, and statistics. The principles of unit operations, transport phenomena, and plant design constitute the focus of chemical engineering in the latter years of the curricula. Experimental methods and instrumentation is the precursor to these subjects. This resource integrates these concepts with statistics and uncertainty analysis to define what is necessary to measure and to control, how precisely and how often.The completely updated second edition is divided into several themes related to data: metrology, notions of statistics, and design of experiments. The book then covers basic principles of sensing devices, with a brand new chapter covering force and mass, followed by pressure, temperature, flow rate, and physico-chemical properties. It continues with chapters that describe how to measure gas and liquid concentrations, how to characterize solids, and finally a new chapter on spectroscopic techniques such as UV/Vis, IR, XRD, XPS, NMR, and XAS. Throughout the book, the author integrates the concepts of uncertainty, along with a historical context and practical examples.A problem solutions manual is available from the author upon request. - Includes the basics for 1st and 2nd year chemical engineers, providing a foundation for unit operations and transport phenomena - Features many practical examples - Offers exercises for students at the end of each chapter - Includes up-to-date detailed drawings and photos of equipment
Formerly published by Chicago Business Press, now published by Sage Written in an engaging and student-friendly manner, Sales Force Management provides a blend of cutting-edge research and practical strategies. Author Gregory A. Rich delves into the challenges faced by today′s sales managers, covering topics such as technology, globalization, and social selling, keeping your students up-to-date with the latest developments in the field.
Barack Obama’s inauguration as the first African American president of the United States has caused many commentators to conclude that America has entered a postracial age. The Preacher and the Politician argues otherwise, reminding us that, far from inevitable, Obama’s nomination was nearly derailed by his relationship with Jeremiah Wright, the outspoken former pastor of Trinity United Church of Christ on the South Side of Chicago. The media storm surrounding Wright’s sermons, the historians Clarence E. Walker and Gregory D. Smithers suggest, reveals that America’s fraught racial past is very much with us, only slightly less obvious. With meticulous research and insightful analysis, Walker and Smithers take us back to the Democratic primary season of 2008, viewing the controversy surrounding Wright in the context of enduring religious, political, and racial dynamics in American history. In the process they expose how the persistence of institutional racism, and racial stereotypes, became a significant hurdle for Obama in his quest for the presidency. The authors situate Wright's preaching in African American religious traditions dating back to the eighteenth century, but they also place his sermons in a broader prophetic strain of Protestantism that transcends racial categories. This latter connection was consistently missed or ignored by pundits on the right and the left who sought to paint the story in simplistic, and racially defined, terms. Obama’s connection with Wright gave rise to criticism that, according to Walker and Smithers, sits squarely in the American political tradition, where certain words are meant to incite racial fear, in the case of Obama with charges that the candidate was unpatriotic, a Marxist, a Black Nationalist, or a Muslim. Once Obama became the Democratic nominee, the day of his election still saw ballot measures rejecting affirmative action and undermining the civil rights of other groups. The Preacher and the Politician is a concise and timely study that reminds us of the need to continue to confront the legacy of racism even as we celebrate advances in racial equality and opportunity.
The proverbial American dream of owning a home has become an all-too-real nightmare for a growing number of families. The most vulnerable segments of our society—including minorities, the elderly, and working families—are being victimized by financiers who lure them into commitments they cannot fulfill. Collectively known as predatory lending, these practices include offering higher interest rates than can be justified by the risk, high pre-payment penalties that lock families into exploitative loans, and monstrous balloon payments that often result in default and the loss of the home. The net result can be disastrous: damage to one's credit rating, bankruptcy, and even the loss of lifelong savings. Why the Poor Pay More is an incisive exposure of these practices: how they have evolved, why they have become so prevalent in recent years, and how their negative effects can be quantified. It features in-depth analysis from prominent scholars, legal experts, and community leaders, who shed new light on the social, political, and economic consequences of predatory lending. Why the Poor Pay More is much more than an indictment of these insidious discriminatory practices. It is a call to arms for anyone concerned about how the financial-political system can be corrupted to serve the needs of the wealthy. Highlighting community initiatives already underway to combat predatory lending and an extensive listing of practical resources, Why the Poor Pay More outlines active roles that individuals, advocacy groups, financial and legal service providers, and policymakers can play in reversing this destructive trend.
New Albany's historic homes boast unique histories and fascinating stories of those who inhabited them. Founded in 1813 below the falls of the Ohio River, the city was Indiana's most populous by the middle of the nineteenth century. Many leading citizens built grand mansions and family dwellings that beamed with prosperity and influence. The architectural legacy during these formative years continued into the early twentieth century and produced historic neighborhoods with a rich collection of housing styles. Join authors David C. Barksdale and Gregory A. Sekula as they delve into the history of New Albany's most cherished old homes.
Communicate Science Papers, Presentations, and Posters Effectively is a guidebook on science writing and communication that professors, students, and professionals in the STEM fields can use in a practical way. This book advocates a clear and concise writing and presenting style, enabling users to concentrate on content. The text is useful to both native and non-native English speakers. The book includes chapters on the publishing industry (discussing bibliometrics, h-indexes, and citations), plagiarism, and how to report data properly. It also offers practical guidance for writing equations and provides the reader with extensive practice material consisting of both exercises and solutions. - Covers how to accurately and clearly exhibit results, ideas, and conclusions - Identifies phrases common in scientific literature that should never be used - Discusses the theory of presentation, including "before and after examples highlighting best practices - Provides concrete, step-by-step examples on how to make camera ready graphs and tables
Ever since the DeAnza expedition camped in the area in 1776, residents and visitors have been making their way to San Mateo--situated in the shadow of its famous northern neighbor, San Francisco. This book trains the spotlight on the unique peninsular city of San Mateo, and illustrates its development from sleepy, oak-studded ranchos to today's bustling city with its own college, three high schools, churches, hospitals, and a population approaching 100,000.
Development, deployment, and evaluation of interactive technologies for individuals with autism have been rapidly increasing over the last decade. There is great promise for the use of these types of technologies to enrich interventions, facilitate communication, and support data collection. Emerging technologies in this area also have the potential to enhance assessment and diagnosis of individuals with autism, to understand the nature of autism, and to help researchers conduct basic and applied research. This book provides an in-depth review of the historical and state-of-the-art use of technology by and for individuals with autism. The intention is to give readers a comprehensive background in order to understand what has been done and what promises and challenges lie ahead. By providing a classification scheme and general review, this book can also help technology designers and researchers better understand what technologies have been successful, what problems remain open, and where innovations can further address challenges and opportunities for individuals with autism and the variety of stakeholders connected to them.
This book provides an in-depth review of the historical and state-of-the-art use of technology by and for individuals with autism. The design, development, deployment, and evaluation of interactive technologies for use by and with individuals with autism have been rapidly increasing over the last few decades. There is great promise for the use of these technologies to enrich lives, improve the experience of interventions, help with learning, facilitate communication, support data collection, and promote understanding. Emerging technologies in this area also have the potential to enhance assessment and diagnosis of autism, to understand the nature and lived experience of autism, and to help researchers conduct basic and applied research. The intention of this book is to give readers a comprehensive background for understanding what work has already been completed and its impact as well as what promises and challenges lie ahead. A large majority of existing technologies have been designed for autistic children, there is increased interest in technology’s intersection with the lived experiences of autistic adults. By providing a classification scheme and general review, this book can help technology designers, researchers, autistic people, and their advocates better understand how technologies have been successful or unsuccessful, what problems remain open, and where innovations can further address challenges and opportunities for individuals with autism and the variety of stakeholders connected to them.
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