Gregory L. Holmes's Books

Handbook of Epilepsy

By: Thomas R. Browne,Gregory L. Holmes

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Now updated, this bestselling reference is a practical point-of-care guide to the diagnosis and management of epilepsy. This edition's updated coverage of drug therapy includes current American Academy of Neurology guidelines, new drugs, newly approved indications, and more.

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Page Count

292

Publisher

Jones & Bartlett Learning

Published Date

ISBN 10

0781773970

ISBN 13

9780781773973

Children with Seizures

A Guide for Parents, Teachers, and Other Professionals

By: Martin L. Kutscher,Gregory L. Holmes

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Children with Seizures

A Guide for Parents, Teachers, and Other Professionals

By: Martin L. Kutscher,Gregory L. Holmes

This concise, accessible handbook for families, friends and carers of children with seizures provides all the information they need to approach seizures from a position of strength. Part 1 discusses types and causes of seizures, and what to do during a seizure. The medical concepts and technical terminology as well as the available tests and treatments, including anticonvulsant medication, are clearly explained. The author also addresses some of the emotional and social issues that may arise, and there are chapters for kids and teens to read themselves or with their parents. Part 2 covers some of the most common epilepsy syndromes in more detail. Further reading and useful contacts are also provided. This reassuring, informal, and upbeat book will reinforce and help clarify the discussion with the child's treating medical professional.

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Page Count

153

Publisher

Jessica Kingsley Publishers

Published Date

ISBN 10

1843108232

ISBN 13

9781843108238

Pediatric Neurology

By: Gregory L. Holmes MD,Peter M. Bingham MD

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Pediatric Neurology

By: Gregory L. Holmes MD,Peter M. Bingham MD

Part of the "What Do I Do Now?" series, Pediatric Neurology uses a case-based approach to cover common and important topics in the diagnosis and treatment of neurologic conditions in children. Each chapter provides a discussion of the diagnosis, key points to remember, and selected references for further reading. For this edition, the table of contents has been reorganized, and all cases and references have been updated. New cases have been added including: Charcot Marie Tooth, NMDA Receptor AB Encephalopathy, Guillain Barre Syndrome, Transverse Myelitis, Tics/Tourette Syndrome, Conversion Disorder, Chronic Daily Headache, and Chiari I Malformation. Pediatric Neurology is an engaging collection of thought-provoking cases which clinicians can utilize when they encounter difficult patients. The volume is also a self-assessment tool that tests the reader's ability to answer the question, "What do I do now?

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Page Count

217

Publisher

Oxford University Press

Published Date

ISBN 10

0190601523

ISBN 13

9780190601522

Behavioral Aspects of Epilepsy

Principles and Practice

By: Gregory L. Holmes, MD,Steven C. Shachter, MD,Dorothee GA Kasteleijn-Nolst Trenite, MD MPH

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Behavioral Aspects of Epilepsy

Principles and Practice

By: Gregory L. Holmes, MD,Steven C. Shachter, MD,Dorothee GA Kasteleijn-Nolst Trenite, MD MPH

The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. Behavioral Aspects of Epilepsy: Principles and Practice is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers in the fields of epilepsy, neuroscience, and psychology/psychiatry. Behavioral aspects of epilepsy include a patient's experiences during seizures, his or her reaction during and between seizures, the frequency of episodes and what can be determined from the number of seizures. With contributions by dozens of leading international experts, this is the only book to cover all aspects of this critical emerging science. Adult and pediatric patients, animal models, and epilepsy surgery and its effects are all covered in detail. Behavioral Aspects of Epilepsy is the only source for up-to-date information on a topic that has significant and growing interest in the medical community. This comprehensive, authoritative text has a bench to bedside, approach that covers: The mechanisms underlying epilepsy and behavior Neurophysiologic function Neuropsychiatric and behavioral disorders in patients with epilepsy The effects of treatments and surgery on behavior Pediatric and adolescent epilepsy Disorders associated with epilepsy that impact behavior And much more

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Page Count

554

Publisher

Demos Medical Publishing

Published Date

ISBN 10

1934559881

ISBN 13

9781934559888

Disputed Inheritance

The Battle over Mendel and the Future of Biology

By: Gregory Radick

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Disputed Inheritance

The Battle over Mendel and the Future of Biology

By: Gregory Radick

A root-and-branch rethinking of how history has shaped the science of genetics. In 1900, almost no one had heard of Gregor Mendel. Ten years later, he was famous as the father of a new science of heredity—genetics. Even today, Mendelian ideas serve as a standard point of entry for learning about genes. The message students receive is plain: the twenty-first century owes an enlightened understanding of how biological inheritance really works to the persistence of an intellectual inheritance that traces back to Mendel’s garden. Disputed Inheritance turns that message on its head. As Gregory Radick shows, Mendelian ideas became foundational not because they match reality—little in nature behaves like Mendel’s peas—but because, in England in the early years of the twentieth century, a ferocious debate ended as it did. On one side was the Cambridge biologist William Bateson, who, in Mendel’s name, wanted biology and society reorganized around the recognition that heredity is destiny. On the other side was the Oxford biologist W. F. R. Weldon, who, admiring Mendel's discoveries in a limited way, thought Bateson's "Mendelism" represented a backward step, since it pushed growing knowledge of the modifying role of environments, internal and external, to the margins. Weldon's untimely death in 1906, before he could finish a book setting out his alternative vision, is, Radick suggests, what sealed the Mendelian victory. Bringing together extensive archival research with searching analyses of the nature of science and history, Disputed Inheritance challenges the way we think about genetics and its possibilities, past, present, and future.

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Page Count

643

Publisher

University of Chicago Press

Published Date

ISBN 10

0226822710

ISBN 13

9780226822716

Pediatric Neurology Part I

Chapter 47. Brain maturation and epilepsy

By: Olivier Dulac,Mathieu Milh,Gregory L. Holmes

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Pediatric Neurology Part I

Chapter 47. Brain maturation and epilepsy

By: Olivier Dulac,Mathieu Milh,Gregory L. Holmes

At full term, both glutamate and gamma-amino-butyric acid (GABA) are excitatory; cortical synapses are beginning to appear, there is little myelin in the cerebral hemispheres, and long tracts hardly start to develop. Neonatal myoclonic encephalopathy can result from premature activation of N-methyl-D-aspartate (NMDA) transmission. Benign neonatal seizures and migrating partial seizures in infancy could involve excessive or premature excitability of deep cortical layers. Benign rolandic epilepsy and continuous spike waves in slow sleep are consistent with an excess of both excitatory and inhibitory cortical synapses. West and Lennox−Gastaut syndromes express age-related diffuse cortical hyperexcitability, the pattern depending on the age of occurrence; synchronization of spikes is becoming possible with maturation of the myelin. Idiopathic generalized epilepsy is itself modulated by maturation that causes frontal hyperexcitability generating myoclonic-astatic seizures, between the ages of infantile and juvenile myoclonic epilepsies. Physiological delay of hippocampo-neocortical pathways maturation could account for the delayed occurrence of mesial temporal epilepsy following infantile damage, whereas premature maturation could contribute to fronto-temporal damage characteristic of fever-induced epileptic encephalopathy in school-age children, a dramatic school-age epileptic encephalopathy.

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Elsevier Inc. Chapters

Published Date

ISBN 10

0128077522

ISBN 13

9780128077528

Pediatric Neurology

By: Gregory L. Holmes,Peter M. Bingham

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Pediatric Neurology

By: Gregory L. Holmes,Peter M. Bingham

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217

Publisher

Oxford University Press

Published Date

ISBN 10

0190601507

ISBN 13

9780190601508

Epilepsy

By: Gregory Goodfellow,Greg Goodfellow

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Epilepsy

By: Gregory Goodfellow,Greg Goodfellow

Discusses the causes, diagnosis, and treatment of epilepsy, the types of seizures, and the challenges of living with the disease.

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Page Count

102

Published Date

ISBN 10

1560067012

ISBN 13

9781560067016

Pediatric Neurology

By: Gregory Holmes

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Pediatric Neurology

By: Gregory Holmes

What do I do now? Pediatric patients with neurological symptoms or problems pose many clinical challenges and even experienced clinicians occasionally arrive at the point where diagnostic, work-up, treatment, or prognostic thinking becomes blocked. From time to time, children are brought into the pediatrician's office with puzzling neurological symptoms--breath holding spells, refusal to walk, infantile spasms, skin lesions, floppy or absent reflexes--that leave their doctors wondering "what do I do now?" Pediatric Neurology serves the need for a quick reference tool to address these perplexing pediatric neurological symptoms and disorders. Dr. Gregory L. Holmes, Department Chair and Professor of Pediatrics and Neurology at Dartmouth Medical School, presents 28 representative cases of both common and rare pediatric neurological problems and diseases including but not limited to: Dopamine Responsive Dystonia, Fragile X Syndrome, Hashimoto's Encephalopathy and Rett Syndrome. The bedside consultation presentation of the cases encourages the reader, whether she or he be a pediatrician, primary care practitioner or medical student, to formulate a differential diagnosis and treatment plan for a wide variety of pediatric neurological problems and diseases.

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Page Count

164

Publisher

Oxford University Press

Published Date

ISBN 10

0199750475

ISBN 13

9780199750474

Book's by Gregory L. Holmes

Handbook of Epilepsy

Handbook of Epilepsy

Children with Seizures

Children with Seizures

Pediatric Neurology

Pediatric Neurology

Behavioral Aspects of Epilepsy

Behavioral Aspects of Epilepsy

Disputed Inheritance

Disputed Inheritance

Pediatric Neurology Part I

Pediatric Neurology Part I

Pediatric Neurology

Pediatric Neurology

Epilepsy

Epilepsy

Pediatric Neurology

Pediatric Neurology

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