Provides health professionals with a structured approach to the preventive care of children with congenital disorders. Over 150 conditions ranging from cerebral palsy to Down syndrome are discussed. The large number of conditions covered and the added perspective of a developmental pediatrician (Dr Cooley) provides a valuable resource for carers and parents. For each disorder there is an introductory summary of key information, followed by more detailed listing of general pediatric and speciality concerns, all structured to provide an integrated approach to patient care. For 32 common disorders or disease categories, preventive management checklists are provided: these checklists provide an ongoing record for the child's medical complications and progress and they are designed to be copied and placed in the medical record. The text provides details of medical complications and preventive recommendations supported by key literature and web resources for parents and professionals.
This new edition now titled “Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis” provides the reader with an up-to-date overview of microarrays, fragile sites, copy number variations and whole genome sequencing. Greatly expanding the discussion of microarray analysis in the previous edition of the book, are new chapters on microarray and genomic analysis, plus comprehensive tables on the subtle microdeletions and microduplications that are found on each chromosome, including 235 recurring copy number variants that are associated with well-established or emerging chromosomal syndromes. The current edition features concise information on cytogenetic methods and applications, extending these discussions to DNA analysis and genome sequencing. Sections on euchromatin, heterochromatin, FISH pattern, fragile site, copy number, and DNA sequence variation are integrated with actual clinical examples from cytogenetic laboratories and from clinical practice. The principles that allow for the distinction between benign chromosome / DNA variation and pathogenic heteromorphisms / polymorphisms are discussed and include references to the latest organizational guidelines and genomic or population databases. The two previous incarnations of this book: the ‘Atlas of Human Chromosome Heteromorphism’, and ‘Human Chromosome Variation: Heteromorphism and Polymorphism’ have been standard reference works in most cytogenetic laboratories, used by laboratory directors and clinicians all around the world. While widely used sections from the previous edition on cytogenetic technologies and heteromorphisms are retained intact the present volume adds extensive material on copy number variations (polymorphisms detected by microarray analysis), fragile sites in disease and cancer, and practical views on interpreting emerging technologies, including whole exome sequencing. This book should be of interest to clinicians, technicians and students who are or will be exposed to DNA and/or chromosome analysis and the data derived from these continuously developing techniques. This fully updated book volume will bring the reader up to speed on the latest technologies, their applications, benefits and drawbacks and as such, is a must read for anyone with an interest in DNA and chromosome analysis and the distinction between benign variation and pathogenic mistakes.
Adapted from the groundbreaking bestseller Principles of Comparative Politics, Fourth Edition! Foundations of Comparative Politics, Second Edition presents a scientific approach to the rich world of comparative inquiry, research, and scholarship, providing a guide to cross-national comparison and why it matters. This condensed, more accessible format introduces students to the key questions in comparative politics, using brief insights from tools such as decision, social choice, and game theory to help them understand clearly why some explanations for political phenomena are stronger than others. William Roberts Clark, Matt Golder, and Sona Nadenichek Golder concentrate on describing the core features of regimes and institutions and on analyzing how these fundamental attributes drive variation in the economic and political outcomes we care about most. This approach—constructing and testing theories on political phenomena over basic memorization of country-specific facts—more closely replicates what comparative scholars do to explain, rather than describe. Current examples that show the application of theory help students develop invaluable real-world skills in critical thinking and empirical analysis that they will carry with them long after the course is over. Included with this title: LMS Cartridge: Import this title’s instructor resources into your school’s learning management system (LMS) and save time. Don′t use an LMS? You can still access all of the same online resources for this title via the password-protected Instructor Resource Site. Select the Resources tab on this page to learn more.
Why do some parties coordinate their electoral strategies as part of a pre-electoral coalition, while others choose to compete independently at election time? Scholars have long ignored pre-electoral coalitions in favor of focusing on the government coalitions that form after parliamentary elections. Yet electoral coalitions are common, they affect electoral outcomes, and they have important implications for democratic policy-making itself. The Logic of Pre-Electoral Coalition Formation by Sona Nadenichek Golder includes a combination of methodological approaches (game theoretic, statistical, and historical) to explain why pre-electoral coalitions form in some instances but not in others. The results indicate that pre-electoral coalitions are more likely to form between ideologically compatible parties. They are also more likely to form when the expected coalition size is large (but not too large) and when the potential coalition partners are similar in size. Ideologically polarized party systems and disproportional electoral rules in combination also increase the likelihood of electoral coalition formation. Golder links the analysis of pre-electoral coalition formation to the larger government coalition literature by showing that pre-electoral agreements increase (a) the likelihood that a party will enter government, (b) the ideological compatibility of governments, and (c) the speed with which governments take office. In addition, pre-electoral coalitions provide an opportunity for combining the best elements of the majoritarian vision of democracy with the best elements of the proportional vision of democracy.
William Roberts Clark, Matt Golder, and Sona Nadenichek Golder’s groundbreaking Principles of Comparative Politics offers the most comprehensive and up-to-date introduction to comparative inquiry, research, and scholarship. In this thoroughly revised Third Edition, readers have an even better guide to cross-national comparison and why it matters. Readers are offered a new intuitive take on statistical analyses and a clearer explanation of how to interpret regression results; a thoroughly-revised chapter on culture and democracy that now includes a more extensive discussion of cultural modernization theory and a new overview of survey methods for addressing sensitive topics; and a revised chapter on dictatorships that incorporates a principal-agent framework for understanding authoritarian institutions. Examples from the gender and politics literature have been incorporated into various chapters and empirical examples and data on various types of institutions have been updated. The book's outstanding pedagogy includes more than 250 tables and figures, numerous photos and maps, end of chapter exercises and problem sets, and a broader set of works cited. New to this Edition A new intuitive take on statistical analyses and a clearer explanation of how to interpret regression results are included. A thoroughly-revised chapter on culture and democracy includes a more extensive discussion of cultural modernization theory and a new overview of survey methods for addressing sensitive topics. A revised chapter on dictatorships incorporates a principal-agent framework for understanding authoritarian institutions. Examples from the gender and politics literature have been incorporated into various chapters. Empirical examples and data on various types of institutions have been updated. Online videos and tutorials guide students through some of the methodological components addressed in the book.
Tom Jacobs and his young friend Ryan will unwittingly be the principal witnesses as the afternoon's events unfold. Tom is currently wrestling with the pressure created by the very high expectation of others for his life as a violinist capable of walking the world concert platforms. He is also smarting from a humiliating experience caused by his new classmate Wendy Fraser, even though they have never spoken. Wendy Fraser's world is a dark place-she is a victim of bullying, without love or hope in her life. She is yelling at a God she believes doesn't love or care and probably even exist; caught up in her despair because she didn't die in a suspicious car accident in Asia with her best friend, Rachel. Will the criminal gang thought to be behind the crash reach out against her family again, just because her father's honesty and integrity cost the gang millions? Juliette and her gang of schoolyard bullies are even now stalking Wendy for the perceived further slights they have imagined during the week, even though they have deliberately targeted Wendy all week. These three are about to collide violently in a way that will change their lives forever. How will their response to the unexpected consequences of this collision play out in their lives? What hope is there for their future?
Uncivil Rights is a guide to workers' rights. Detailed descriptions of employment rights issues and methods for protecting and preserving those rights are provided by way of practical, real-life examples.
PreTest is the closest you can get to seeing the USMLE Step 1 before you take it! 500 USMLE-style questions and answers! Great for course review and the USMLE Step 1, PreTest asks the right questions so you’ll know the right answers. You’ll find 500 clinical-vignette style questions and answers along with complete explanations of correct and incorrect answers. The content has been reviewed by students who recently passed their exams, so you know you are studying the most relevant and up-to-date material possible. No other study guide targets what you really need to know in order to pass like PreTest!
Provides health professionals with a structured approach to the preventive care of children with congenital disorders. Over 150 conditions ranging from cerebral palsy to Down syndrome are discussed. The large number of conditions covered and the added perspective of a developmental pediatrician (Dr Cooley) provides a valuable resource for carers and parents. For each disorder there is an introductory summary of key information, followed by more detailed listing of general pediatric and speciality concerns, all structured to provide an integrated approach to patient care. For 32 common disorders or disease categories, preventive management checklists are provided: these checklists provide an ongoing record for the child's medical complications and progress and they are designed to be copied and placed in the medical record. The text provides details of medical complications and preventive recommendations supported by key literature and web resources for parents and professionals.
This new edition now titled “Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis” provides the reader with an up-to-date overview of microarrays, fragile sites, copy number variations and whole genome sequencing. Greatly expanding the discussion of microarray analysis in the previous edition of the book, are new chapters on microarray and genomic analysis, plus comprehensive tables on the subtle microdeletions and microduplications that are found on each chromosome, including 235 recurring copy number variants that are associated with well-established or emerging chromosomal syndromes. The current edition features concise information on cytogenetic methods and applications, extending these discussions to DNA analysis and genome sequencing. Sections on euchromatin, heterochromatin, FISH pattern, fragile site, copy number, and DNA sequence variation are integrated with actual clinical examples from cytogenetic laboratories and from clinical practice. The principles that allow for the distinction between benign chromosome / DNA variation and pathogenic heteromorphisms / polymorphisms are discussed and include references to the latest organizational guidelines and genomic or population databases. The two previous incarnations of this book: the ‘Atlas of Human Chromosome Heteromorphism’, and ‘Human Chromosome Variation: Heteromorphism and Polymorphism’ have been standard reference works in most cytogenetic laboratories, used by laboratory directors and clinicians all around the world. While widely used sections from the previous edition on cytogenetic technologies and heteromorphisms are retained intact the present volume adds extensive material on copy number variations (polymorphisms detected by microarray analysis), fragile sites in disease and cancer, and practical views on interpreting emerging technologies, including whole exome sequencing. This book should be of interest to clinicians, technicians and students who are or will be exposed to DNA and/or chromosome analysis and the data derived from these continuously developing techniques. This fully updated book volume will bring the reader up to speed on the latest technologies, their applications, benefits and drawbacks and as such, is a must read for anyone with an interest in DNA and chromosome analysis and the distinction between benign variation and pathogenic mistakes.
Is your child failing to meet milestones? Have you noticed sluggish feeding and activity? Do you feel something is wrong and have voiced your concerns to your doctor, only to have your doctor brush you off? Or have you been told that your child has pervasive developmental disorder, autism, or mental retardation? If so, this book is for you. Written by Dr. Golder Wilson, a pediatrician/medical geneticist whose own child has a disability, this book offers hope and inspiration. In this book, Dr. Wilson tells the story of six mothers who have children with disabilities. These women not only tell their story, but also give advice on what to do and how best to handle different situations for other families and health professionals. Dr. Wilson then gives his perspective to help physicians better relate to families with disabled children. You will read how these women and their families have incorporated these children into their lives, dealt with the sadness, met obligations, and moved on to happy, fulfilling lives. Six Mothers - Six Stories of disAbility is a must read for parents of disabled
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