The foundation for the subject of mathematical finance was laid nearly 100 years ago by Bachelier in his fundamental work, Theorie de la speculation. In this work, he provided the first treatment of Brownian motion. Since then, the research of Markowitz, and then of Black, Merton, Scholes, and Samuelson brought remarkable and important strides in the field. A few years later, Harrison and Kreps demonstrated the fundamental role of martingales and stochastic analysis in constructing and understanding models for financial markets. The connection opened the door for a flood of mathematical developments and growth. Concurrently with these mathematical advances, markets have grown, and developments in both academia and industry continue to expand. This lively activity inspired an AMS Short Course at the Joint Mathematics Meetings in San Diego (CA). The present volume includes the written results of that course. Articles are featured by an impressive list of recognized researchers and practitioners. Their contributions present deep results, pose challenging questions, and suggest directions for future research. This collection offers compelling introductory articles on this new, exciting, and rapidly growing field.
Written by top practitioners in the field of neuropsychological screening, Screening for Brain Impairment is the extensively updated new edition of the classic resource. Valuable to a broad range of medical and mental health practitioners, this new edition reflects enormous changes to the field over the past 13 years. Each chapter contains updated information and new empirical data, including extensive information on neurological and psychiatric disorders, adult attention deficit disorder, and screening for and assessing the emotional correlates of brain impairment. Also included are new chapters on computerized assessment and developing relations with other professionals, including clinical neuropsychologists, neurologists, primary care physicians, neurosurgeons, and psychiatrists.
The Ultimate Book of Gangster Movies provides extensive reviews of the Top 100 gangster films of all time, including sidebars like "Reality Check," "Hit and Miss," "I Know That Guy," "Body Count," and other fun and informative features.
Designed to meet the distinctive needs of today’s undergraduates in communication sciences and disorders, Fundamentals of Anatomy and Physiology of Speech, Language, and Hearing provides an accessible and visually engaging comprehensive introduction to the structures and functions of respiration, phonation, voice, articulation, resonance, swallowing, hearing, balance, neuroanatomy, and neurophysiology. Authors Glen M. Tellis and M. Hunter Manasco use their experiences in the classroom to inform their approach to student learning. Each topic is concisely introduced in bullet-point form and then augmented with more detailed text, boxed content, illustrations, and tables. In addition to this easily manageable method of presenting information, the book also provides extensive supplementary material on a companion website. This technology-supported pedagogical approach allows students to review concepts via detailed study guides with anatomical labels, explore cadaver images, and view them as an extension of the textbook. This is the only text with real cadaver images from Anatomage’s 3D dissection table allowing an unparalleled glimpse into the anatomical structures of the human body, featuring true-to-life colors with an impressive level of detail. Drs. Tellis and Manasco’s active learning approach will encourage and challenge students to think deeply and critically about the anatomy and physiology related to speech, language, and hearing. This immersive and technology-centered process is intended to increase student comprehension, retention, performance, and enjoyment of the material. Key Features * Unique bullet-point format to increase comprehension and retention * 340+ color figures boost student engagement and include both anatomical illustrations and real human cadaver images from Anatomage’s 3D anatomy table * Chapter learning objectives to guide instruction * Boxed features with historical and cultural contexts * Bolded key terms and glossary Disclaimer: Please note that online ancillary content (such as documents, quizzes, audio, and video, etc.) may not be included as published in the original print version of this book.
From Dreams to Disillusionment is the first book to cover the planning experiment of the 1960s in full historical detail. Other countries' planners made the approach seem successful, however, the experiment eventually failed, doomed to disappoint given unrealistic expectations, lack of time and an overburdened government.
This volume is a comprehensive statistical analysis of the 2005 UK general election. The pages are tabulated in columns under the headings constituency name, electorate, 2001 result, turnout, candidate, party, votes, percent share, lost deposit, and change 2001-2005.
This stimulating study of Charlotte Brontë's novels draws on extensive original research in a range of early Victorian writings, on subjects ranging from women's day-dreaming to sanitary reform, from the Great Exhibition to early Victorian religious thought. It is not, however, merely a study of context. Through a close consideration of the ways in which Brontë's novels engage with the thinking of their time, it offers a powerful argument for the "literary" as a distinctive mode of intelligence, and reveals a Charlotte Brontë more alert to her historical moment and far more aesthetically sophisticated than she has usually been taken to be. The study will be of interest not only to students of Victorian literature and society, but also to those literary critics and theorists who are beginning to reconsider the nature of the aesthetic and its relation to ideology.
Tells the stories of Australia's best known pop and rock songs. Aussie Rock Anthems names the top 40 classic Australian songs and tells the stories behind them – many unknown. From Hunters & Collectors' 'Throw Your Arms Around Me' to INXS's 'Don't Change' and Redgum's 'I Was Only 19', author Glen Humphries unearths hidden gems and surprising back stories about the bands. It's a celebration of great Australian music that will have you reaching for old vinyl or phone apps to give some of these classics another listen. Chances are, each song is not what you had assumed..
This important subject of Diagnosis of and Treatment for Neurobehavioral manifestations of neurologic disease is directed by three leaders of this field - Dr. Alizeza Minagar, Dr. Glen Finney, and Dr. Kenneth Heilman. Topics include: Neurobehavioral testing for mental status; Behavioral neurology of vascular neurology; Alzheimer's disease; Frontotemporal dementia; Traumatic brain injury; Parkinsonian Syndromes (e.g., Parkinson's disease, Lewy body dementia, progressive supranuclear palsy, corticobasal disease, multisystem atrophy); Behavioral neurology of multiple sclerosis and autoimmune encephalopathies; Infectious Diseases (Neuro-AIDS, Neurosyphilis, HSV); Neurobehavioral aspects of systemic disease; Neurobehavioral aspects of epilepsy; Behavioral neurology aspects of nutritional deficiencies; Neurobehavioral aspects of mitochondrial disease; and Medicinal-induced behavioral disorders.
Illustrative examples from recent research publications and "classic" studies are prominently featured throughout the book. Research techniques are highlighted in "special interest" boxes. Illustrations and descriptions of research techniques are provided with examples such as fire-scars from trees used to reconstruct disturbance, fossil pollen used to reconstruct vegetation change and plant migration, transect and quadrate sampling. Includes key biogeographical theories that link space and time to the distribution of life. Some of these theories include: 1. Ranges, Reflicts, Refuges, Corridors, Barriers, 2. Centers of Origins, 3. Cladistics, 4. Variance, 5. Island BioGeography, 6. Diversity Theory, 7. Gap Analysis for Conservation.
A Canadian platoon embarked under the cover of darkness in late October 1944 near Cesna Italy assigned with a tank hunting mission. Their goal was to help Allied forces establish a bridgehead to build a critical crossing across the Savio River. Ongoing heavy fire from German tanks required an elite group of Canadian soldiers with tank killing experience to break the German advance and in less than one hour, one man changed Canadian history forever. This is a story which outlines the heroic military victory in the Battle of Italy, 1943-45 and the extraordinary valour of Private Ernest "Smokey" Smith who single-handedly destroyed multiple German Panzer tanks with projectile infantry anti-tank guns and protected a wounded comrade with a sub-machine gun from opposition forces. Born in New Westminster, BC Ernest Smith grew up during Canada's depression of the 1930s. Like many young men at the time, Smith "rode the rails" is search of employment where he eventually volunteered and enlisted in the Canadian Expeditionary Force to fight in the new war of 1939. Smokey was an exemplary soldier whose bravery ultimately resulted in him becoming Canada's last surviving recipient of the Victoria Cross.
In this highly acclaimed work first published in 1974, Glen H. Elder Jr. presents the first longitudinal study of a Depression cohort. He follows 167 individuals born in 1920–1921 from their elementar
Presenting both a theoretical foundation and proven strategies for helping caregivers become more attuned and responsive to their young children's emotional needs (ages 0-5), this is the first comprehensive presentation of the Circle of Security (COS) intervention. The book lucidly explains the conceptual underpinnings of COS and demonstrates the innovative attachment-based assessment and intervention strategies in rich clinical detail, including three chapter-length case examples. Reproducible forms and handouts can be downloaded and printed in a convenient 8 1/2" x 11" size. COS is an effective research-based program that has been implemented throughout the world with children and parents experiencing attachment difficulties. The authors are corecipients of the 2013 Bowlby-Ainsworth Award, presented by the New York Attachment Consortium, for developing and implementing COS. See also the authors' related parent guide: Raising a Secure Child: How Circle of Security Parenting Can Help You Nurture Your Child's Attachment, Emotional Resilience, and Freedom to Explore.
A comprehensive overview of the new business context for biopharma companies, featuring numerous case studies and state-of-the-art marketing models Biotechnology has developed into a key innovation driver especially in the field of human healthcare. But as the biopharma industry continues to grow and expand its reach, development costs are colliding with aging demographics and cost-containment policies of private and public payers. Concurrently, the development and increased affordability of sophisticated digital technologies has fundamentally altered many industries including healthcare. The arrival of new information technology (infotech) companies on the healthcare scene presents both opportunities and challenges for the biopharma business model. To capitalize on new digital technologies from R&D through commercialization requires industry leaders to adopt new business models, develop new digital and data capabilities, and partner with innovators and payers worldwide. Written by two experts, both of whom have had decades of experience in the field, this book provides a comprehensive overview of the new business context and marketing models for biotech companies. Informed by extensive input by senior biotech executives and leading consultancies serving the industry, it analyzes the strategies and key success factors for the financing, development, and commercialization of novel therapeutic products, including strategies for engagement with patients, physicians and healthcare payers. Throughout case studies provide researchers, corporate marketers, senior managers, consultants, financial analysts, and other professionals involved in the biotech sector with insights, ideas, and models. JACQUALYN FOUSE, PhD, RETIRED PRESIDENT AND CHIEF OPERATING OFFICER, CELGENE “Biotech companies have long been innovators, using the latest technologies to enable cutting edge science to help patients with serious diseases. This book is essential to help biotech firms understand how they can–and must–apply the newest technologies including disruptive ones, alongside science, to innovate and bring new value to the healthcare system.” BRUCE DARROW, MD, PhD, CHIEF MEDICAL INFORMATION OFFICER, MOUNT SINAI HEALTH SYSTEM “Simon and Giovannetti have written an essential user’s manual explaining the complicated interplay of the patients who deserve cutting-edge medical care, the biotechnology companies (big and small) creating the breakthroughs, and the healthcare organizations and clinicians who bridge those worlds.” EMMANUEL BLIN, FORMER CHIEF STRATEGY OFFICER AND SENIOR VICE PRESIDENT, BRISTOL-MYERS SQUIBB “If you want to know where biopharma is going, read this book! Our industry is facing unprecedented opportunities driven by major scientific breakthroughs, while transforming itself to address accelerated landscape changes driven by digital revolutions and the emergence of value-based healthcare worldwide. In this ever-changing context, we all need to focus everything we do on the patients. They are why we exist as an industry, and this is ultimately what this insightful essay is really about.” JOHN MARAGANORE, PRESIDENT AND CHIEF EXECUTIVE OFFICER, ALNYLAM PHARMACEUTICALS “Since the mapping of the human genome was completed nearly 15 years ago, the biotechnology industry has led the rapid translation of raw science to today’s innovative medicines. However, the work does not stop in the lab. Delivering these novel medicines to patients is a complex and multifaceted process, which is elegantly described in this new book.”
Human adenoviruses play a central role in human diseases and as vectors for vaccines and gene delivery. This monograph describes the underlying principles of adenovirus molecular and structural biology, pathogenesis, antiviral measures and vector development. Much of the history of this virus and the many contributions made by its study are embedded in these discussions. Topics and questions that require further investigation are also considered.Although current virology textbooks cover topics related to adenoviruses, this book provides a comprehensive description of the virus and its interactions with the host. Students and researchers with a particular interest in adenoviruses, gene therapists, and virologists interested in viral pathogenesis will benefit from this book, which presents a unique integration of the basics with applied research in the field.
This is the 7th Edition of John Tiley's major text on revenue law, now massively restructured to focus upon the UK Tax system, Income Tax, Capital Gains Tax, and Inheritance Tax. What were previously sections dealing with Corporation Tax, International and European Tax, Savings and Charities have been spun-off to an entirely new book entitled Advanced Topics in Revenue Law. While this narrowing of the scope of Revenue Law means that it focuses on the most important UK taxes, its reduced size also makes it a more manageable and portable volume for law students and practitioners. As with previous editions, the text has been revised to incorporate changes wrought by new enactments in the past four years. This, however, remains the only book on tax law which continues to explain the new law found in ITEPA, ITTOIA and ITA in light of its legislative predecessors, with references to the former enactments still remaining where relevant. Those familiar with the old law of income tax but wanting to find their way round the new will find this work particularly valuable. The book is designed for law students taking the subject in the final year of their law degree course or for more advanced courses and is intended to be of interest to all who enjoy tax law. Its purpose is not only to provide an account of the rules but to include citation of the relevant literature from legal periodicals and some discussion of, or reference to, the background material in terms of policy, history or other countries' tax systems.
Professor-Politician challenges common depictions of politics as a constant struggle of good-versus-evil and heroes-versus-villains, with "dirty politics" usually winning. The truth is that good government can prevail in Montgomery and Washington. Journalist Geni Certain recounts Glen Browder's civic adventures as one of Alabama's prominent scholars and public officials over the past half-century. This is a story of practical and reform politics told by someone specially positioned to comment on the Alabama government and American democracy. Certain interviewed knowledgeable people, researched public records, and scoured the Browder Collection at Jacksonville State University for this intriguing and inspiring biography of a civic-oriented leader.
For some time immunotherapy has been heralded as a breakthrough approach for cancer treatment. Although the potential of this strategy remains solid, the approach needs considerable refinement. Whilst some programmes are looking to increase the understanding of molecular and cellular mechanisms underlying the stimulation of antitumor immunity, others are trying to find the most appropriate clinical setting that will reveal the role of the immune system in combating cancer. Among the most important discoveries have been tumor-specific antigens. This thematic volume highlights some key issues and discusses where they may move forward. It has been put together by two leading cancer immunotherapists from two eminent institutions that focus on cancer research.
This is the first book to cover the British people’s late twentieth century engagement with water in all its domestic, national and international forms, and from bathing and household chores to controversies about maritime pollution. The British Isles, a relatively wet and rainy archipelago, cannot in any way be said to be short of liquid resources. Even so, it was the site of highly contentious and revealing political controversies over the meaning and use of water after the Second World War. A series of such issues divided political parties, pressure groups, government and voters, and form the subject matter of this book: problems as diverse as flood defence to river and beach cleanliness, from the teaching of swimming to the installation of hot and cold running water in the home, from international controls over maritime pollution, and from the different housework duties of men and women to the British state’s proposals to fluoridise the drinking water supply.
This is the ninth edition of John Tiley's major text on revenue law, covering the UK tax system, income tax, capital gains tax and inheritance tax, as well as incorporating sections dealing with corporation tax, international and European tax, savings and charities. This new edition is fully revised and updated with the latest case law, statutory and other developments, including Finance Act 2019. The book is designed for law students taking the subject in the final year of their law degree, or for more advanced courses, and is intended to be of interest to all who enjoy tax law. Its purpose is not only to provide an account of the rules but also to include citation of the relevant literature from legal periodicals and some discussion of, or reference to, the background material in terms of policy, history or other countries' tax systems. Copy the URL below to read a 2021 supplement highlighting new developments since the book's publication in 2019: https://www.bloomsbury.com/media/2v1ej5vw/tileys-revenue-law-supplement-2021.pdf
The Roman province of Arabia occupied a crucial corner of the Mediterranean world, encompassing most of what is now Jordan, southern Syria, northwest Saudi Arabia, and the Negev. Mr. Bowersock's book is the first authoritative history of the region from the fourth century B.C. to the age of Constantine. The book opens with the arrival of the Nahataean Arabs in their magnificent capital at Petra and describes the growth of their hellenized culture based on trade in perfume and spices. It traces the transformation of the region from an Arab kingdom under Roman influence into an imperial province, one that played an increasingly important role in the Roman strategy for control of the Near East. While the primary emphasis is on the relations of the Arabs of the region with the Romans, their interactions with neighboring states, Jewish, Egyptian, and Syrian, are also stressed. The narrative concludes with the breakup of the Roman province at the start of the Byzantine age.
This book re-examines the role of urban policy and planning in relation to the housing market in an era of global uncertainty and change. The relationship between planning and the housing market is a contested problem across research, policy, and practice. Problems with housing supply and affordability in many nations have been linked to planning system constraints, while the global financial crisis has raised new questions about the role of urban planning regulation and processes in responding to housing market trends. With reference to international cases from the United Kingdom, the United States, Ireland, Hong Kong and Australia, the book examines how different systems of urban planning and governance address complex and dynamic housing market trends. It also offers practical guidance on how urban planning can support an efficient supply of appropriate and affordable homes in preferred locations. A detailed study, which explains and decodes the workings of the planning system and housing market, this book will be of particular interest to scholars of human geography and urban planning, as well as housing policy makers and practitioners. To view Nicole Gurran’s related TEDx talk please visit: Housing Crisis? How about housing solutions. TEDx Sydney 2018 (http://bit.ly/2psfpMw)
Examining cycling from a range of geographical perspectives, this book uses historical and contemporary case studies to look at the history, politics, economy and culture of cycling. Pursuing a post-structural position in viewing understandings of the bicycle as contingent upon time and place, author Glen Norcliffe argues for the need for widespread processes such as gendered use of the bicycle, the Cyclists’ Rights Movement, and the globalization of bicycle-making to be interpreted in different ways in different settings. With this in mind, the essays in the book are divided into two sections: relational aspects are examined as Spaces of Cycling which treats technological development, innovation, and the location of production and trade of cycles, while Places of Cycling interprets specific sites of consumption - the streets of the city, in the cycling clubs, among men and women, and at the trade show. Written from a geographer’s integrative perspective to offer a broad understanding of cycling, this book will also be of interest to other social scientists in urban studies, cultural studies, technology and society, sociology, history and environmental planning.
This book explores the historical and social foundations of Canadian higher education and provides a detailed analysis of university boards within this broader context of university governance. By examining rich empirical data from a sociological perspective, it offers unique insights into the role of boards, and the structures and practices that frame their work. It explores board composition, the professional backgrounds of board members, how members perceive their role, and the complex relationships between the board and the university president. The authors also compare and contrast the Canadian experience with governance reforms in Europe and other regions over recent decades. Drawing on multiple theoretical perspectives, the authors provide a nuanced analysis of the role of boards in terms of oversight, protecting university autonomy, representing societal interests, and dealing with increasing complexity and expectations. This innovative, original study makes an enormous contribution to our understanding of the role and work of Canadian university boards, and to international scholarship on higher education governance. It will appeal to scholars and researchers with interests across higher education, international and comparative education, and the sociology of education.
This Brief will review the methods that are currently available for the detection, isolation, and typing of pathogenic E. coli with a particular focus on foodborne diseases caused by the Shiga toxigenic E. coli group, which have been implicated in a number of significant outbreaks in recent years. Pathogenic forms of E. coli can cause a variety of diarrheal diseases in hosts due to the presence of specific colonization and virulence factors, and pathogenicity-associated genes, which are generally not present in other E. coli. Six pathotypes of pathogenic E. coli are recognized (Shiga toxigenic E. coli, Enteropathogenic E. coli, Enterotoxigenic E. coli, Enteroinvasive E. coli, Enteroaggregative E. coli and Diffusely Adherent E. coli) and certain strains among these groups are major public health concerns due to the severity of disease that they can cause. Methods to detect and isolate these pathogens from a variety of sources are constantly evolving. In addition, the accumulation of knowledge on these pathogens allows for improved intervention strategies.
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